Author results

2H8N
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STRUCTURE OF A GLUTAMINE-RICH DOMAIN FROM HISTONE DEACETYLASE 4
Descriptor:Histone deacetylase 4
Authors:Guo, L., Han, A., Bates, D.L., Chen, L.
Deposit date:2006-06-07
Release date:2007-02-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of a conserved N-terminal domain of histone deacetylase 4 reveals functional insights into glutamine-rich domains.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2O94
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THE 97H/F MUTANT STRUCTURE OF A GLUTAMINE-RICH DOMAIN FROM HISTONE DEACETYLASE 4
Descriptor:Histone deacetylase 4
Authors:Guo, L., Han, A., Bates, D.L., Chen, L.
Deposit date:2006-12-13
Release date:2007-02-27
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of a conserved N-terminal domain of histone deacetylase 4 reveals functional insights into glutamine-rich domains.
Proc.Natl.Acad.Sci.Usa, 104, 2007
5YY8
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CRYSTAL STRUCTURE OF THE KELCH DOMAIN OF HUMAN NS1-BP
Descriptor:Influenza virus NS1A-binding protein
Authors:Guo, L., Liu, Y., Liang, H.
Deposit date:2017-12-08
Release date:2018-03-14
Method:X-RAY DIFFRACTION (1.979 Å)
Cite:Crystal structure of the Kelch domain of human NS1-binding protein at 1.98 angstrom resolution.
Acta Crystallogr F Struct Biol Commun, 74, 2018
2JTM
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SOLUTION STRUCTURE OF SSO6901 FROM SULFOLOBUS SOLFATARICUS P2
Descriptor:Putative uncharacterized protein
Authors:Feng, Y., Guo, L., Huang, L., Wang, J.
Deposit date:2007-08-03
Release date:2008-04-29
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Biochemical and structural characterization of Cren7, a novel chromatin protein conserved among Crenarchaea
Nucleic Acids Res., 36, 2008
5GT7
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CRYSTAL STRUCTURE OF ARG-BOUND CASTOR1
Descriptor:GATS-like protein 3, ARGININE, MALONATE ION
Authors:Guo, L., Deng, D.
Deposit date:2016-08-18
Release date:2017-08-23
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.048 Å)
Cite:Crystal structures of arginine sensor CASTOR1 in arginine-bound and ligand free states
Biochem. Biophys. Res. Commun., 508, 2019
5GT8
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CRYSTAL STRUCTURE OF APO-CASTOR1
Descriptor:GATS-like protein 3
Authors:Guo, L., Deng, D.
Deposit date:2016-08-18
Release date:2017-08-23
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of arginine sensor CASTOR1 in arginine-bound and ligand free states
Biochem. Biophys. Res. Commun., 508, 2019
3J9B
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ELECTRON CRYO-MICROSCOPY OF AN RNA POLYMERASE
Descriptor:Polymerase, RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 2, ...
Authors:Chang, S.H., Sun, D.P., Liang, H.H., Wang, J., Li, J., Guo, L., Wang, X.L., Guan, C.C., Boruah, B.M., Yuan, L.M., Feng, F., Yang, M.R., Wojdyla, J., Wang, J.W., Wang, M.T., Wang, H.W., Liu, Y.F.
Deposit date:2014-12-16
Release date:2015-02-18
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Cryo-EM Structure of Influenza Virus RNA Polymerase Complex at 4.3 angstrom Resolution.
Mol.Cell, 2015
2AS5
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STRUCTURE OF THE DNA BINDING DOMAINS OF NFAT AND FOXP2 BOUND SPECIFICALLY TO DNA.
Descriptor:5'-D(TP*TP*AP*GP*GP*AP*AP*AP*AP*TP*TP*TP*GP*TP*TP*TP*CP*AP*TP*AP*GP*)-3', 5'-D(AP*AP*CP*TP*AP*TP*GP*AP*AP*AP*CP*AP*AP*AP*TP*TP*TP*TP*CP*CP*TP*)-3', Nuclear factor of activated T-cells, ...
Authors:Wu, Y., Stroud, J.C., Borde, M., Bates, D.L., Guo, L., Han, A., Rao, A., Chen, L.
Deposit date:2005-08-22
Release date:2006-08-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:FOXP3 Controls Regulatory T Cell Function through Cooperation with NFAT.
Cell(Cambridge,Mass.), 126, 2006
3DFV
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ADJACENT GATA DNA BINDING
Descriptor:DNA (5'-D(*DTP*DTP*DCP*DTP*DGP*DAP*DTP*DAP*DAP*DGP*DAP*DCP*DTP*DTP*DAP*DTP*DCP*DTP*DGP*DC)-3'), DNA (5'-D(*DAP*DAP*DGP*DCP*DAP*DGP*DAP*DTP*DAP*DAP*DGP*DTP*DCP*DTP*DTP*DAP*DTP*DCP*DAP*DG)-3'), Trans-acting T-cell-specific transcription factor GATA-3, ...
Authors:Bates, D.L., Kim, G.K., Guo, L., Chen, L.
Deposit date:2008-06-12
Release date:2008-07-29
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structures of multiple GATA zinc fingers bound to DNA reveal new insights into DNA recognition and self-association by GATA.
J.Mol.Biol., 381, 2008
3DFX
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OPPOSITE GATA DNA BINDING
Descriptor:DNA (5'-D(*DTP*DTP*DGP*DAP*DTP*DAP*DAP*DAP*DTP*DCP*DAP*DGP*DAP*DGP*DAP*DTP*DAP*DAP*DCP*DC)-3'), DNA (5'-D(*DAP*DAP*DGP*DGP*DTP*DTP*DAP*DTP*DCP*DTP*DCP*DTP*DGP*DAP*DTP*DTP*DTP*DAP*DTP*DC)-3'), Trans-acting T-cell-specific transcription factor GATA-3, ...
Authors:Bates, D.L., Kim, G.K., Guo, L., Chen, L.
Deposit date:2008-06-12
Release date:2008-07-29
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structures of multiple GATA zinc fingers bound to DNA reveal new insights into DNA recognition and self-association by GATA.
J.Mol.Biol., 381, 2008
3LWH
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CRYSTAL STRUCTURE OF CREN7-DSDNA COMPLEX
Descriptor:Chromatin protein Cren7, DNA (5'-D(*GP*TP*AP*AP*TP*TP*AP*C)-3')
Authors:Zhang, Z.F., Gong, Y., Guo, L., Jiang, T., Huang, L.
Deposit date:2010-02-23
Release date:2010-05-26
Last modified:2014-03-05
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insights into the interaction of the crenarchaeal chromatin protein Cren7 with DNA
Mol.Microbiol., 76, 2010
3LWI
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CRYSTAL STRUCTURE OF CREN7-DSDNA COMPLEX
Descriptor:Chromatin protein Cren7, DNA (5'-D(*GP*CP*GP*AP*TP*CP*GP*C)-3')
Authors:Zhang, Z.F., Gong, Y., Guo, L., Jiang, T., Huang, L.
Deposit date:2010-02-23
Release date:2010-05-26
Last modified:2014-03-05
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural insights into the interaction of the crenarchaeal chromatin protein Cren7 with DNA
Mol.Microbiol., 76, 2010
3TLQ
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CRYSTAL STRUCTURE OF EAL-LIKE DOMAIN PROTEIN YDIV
Descriptor:Regulatory protein YdiV, PHOSPHATE ION, GLYCEROL
Authors:Li, B., Li, N., Wang, F., Guo, L., Liu, C., Zhu, D., Xu, S., Gu, L.
Deposit date:2011-08-30
Release date:2012-09-12
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Structural insight of a concentration-dependent mechanism by which YdiV inhibits Escherichia coli flagellum biogenesis and motility
Nucleic Acids Res., 40, 2012
5EGM
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DEVELOPMENT OF A NOVEL TRICYCLIC CLASS OF POTENT AND SELECTIVE FIXA INHIBITORS
Descriptor:Coagulation factor IX, SODIUM ION, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, ...
Authors:Meng, D., Andre, P., Bateman, T.J., Berger, R., Chen, Y., Desai, K., Dewnani, S., Ellsworth, K., Feng, D., Geissler, W.M., Guo, L., Hruza, A., Jian, T., Li, H., Parker, D.L., Reichert, P., Sherer, E.C., Smith, C.J., Sonatore, L.M., Tschirret-Guth, R., Wu, J., Xu, J., Zhang, T., Campeau, L., Orr, R., Poirier, M., McCabe-Dunn, j., Araki, K., Nishimura, T., Sakurada, I., Hirabayashi, T., Wood, H.B.
Deposit date:2015-10-27
Release date:2015-11-18
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.841 Å)
Cite:Development of a novel tricyclic class of potent and selective FIXa inhibitors.
Bioorg.Med.Chem.Lett., 25, 2015
2AKE
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STRUCTURE OF HUMAN TRYPTOPHANYL-TRNA SYNTHETASE IN COMPLEX WITH TRNA(TRP)
Descriptor:transfer RNA-Trp, Tryptophanyl-tRNA synthetase, SULFATE ION, ...
Authors:Shen, N., Guo, L., Yang, B., Jin, Y., Ding, J.
Deposit date:2005-08-03
Release date:2006-07-11
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of human tryptophanyl-tRNA synthetase in complex with tRNA(Trp) reveals the molecular basis of tRNA recognition and specificity
Nucleic Acids Res., 34, 2006
2DR2
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STRUCTURE OF HUMAN TRYPTOPHANYL-TRNA SYNTHETASE IN COMPLEX WITH TRNA(TRP)
Descriptor:transfer RNA-Trp, Tryptophanyl-tRNA synthetase, SULFATE ION, ...
Authors:Shen, N., Guo, L., Yang, B., Jin, Y., Ding, J.
Deposit date:2006-06-05
Release date:2006-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of human tryptophanyl-tRNA synthetase in complex with tRNA(Trp) reveals the molecular basis of tRNA recognition and specificity
Nucleic Acids Res., 34, 2006
3M0E
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CRYSTAL STRUCTURE OF THE ATP-BOUND STATE OF WALKER B MUTANT OF NTRC1 ATPASE DOMAIN
Descriptor:Transcriptional regulator (NtrC family), ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Chen, B., Sysoeva, T.A., Chowdhury, S., Rusu, M., Birmanns, S., Guo, L., Hanson, J., Yang, H., Nixon, B.T.
Deposit date:2010-03-02
Release date:2010-11-03
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:Engagement of Arginine Finger to ATP Triggers Large Conformational Changes in NtrC1 AAA+ ATPase for Remodeling Bacterial RNA Polymerase.
Structure, 18, 2010
3ODO
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CRYSTAL STRUCTURE OF THE DH/PH DOMAINS OF P115-RHOGEF
Descriptor:Rho guanine nucleotide exchange factor 1
Authors:Chen, Z., Guo, L., Sprang, S.R., Sternweis, P.C.
Deposit date:2010-08-11
Release date:2011-01-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Modulation of a GEF switch: Autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoREF
Protein Sci., 20, 2011
3ODW
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CRYSTAL STRUCTURE OF THE LINKER-DH/PH DOMAINS OF P115-RHOGEF
Descriptor:Rho guanine nucleotide exchange factor 1
Authors:Chen, Z., Guo, L., Sprang, S.R., Sternweis, P.C.
Deposit date:2010-08-11
Release date:2011-01-05
Last modified:2014-02-19
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Modulation of a GEF switch: Autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoREF
Protein Sci., 20, 2011
3ODX
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CRYSTAL STRUCTURE OF AN N-TERMINALLY TRUNCATED LINKER-DH/PH DOMAINS OF P115-RHOGEF
Descriptor:Rho guanine nucleotide exchange factor 1
Authors:Chen, Z., Guo, L., Sprang, S.R., Sternweis, P.C.
Deposit date:2010-08-12
Release date:2011-01-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Modulation of a GEF switch: Autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoREF
Protein Sci., 20, 2011
3P6A
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CRYSTAL STRUCTURE OF THE DH/PH DOMAINS OF P115-RHOGEF (R399E MUTANT)
Descriptor:Rho guanine nucleotide exchange factor 1
Authors:Chen, Z., Guo, L., Sprang, S.R., Sternweis, P.C.
Deposit date:2010-10-11
Release date:2011-01-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Modulation of a GEF switch: Autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoREF
Protein Sci., 20, 2011
3QZQ
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HUMAN ENTEROVIRUS 71 3C PROTEASE MUTANT E71D IN COMPLEX WITH RUPINTRIVIR
Descriptor:3C protein, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER
Authors:Wang, J., Fan, T., Yao, X., Wu, Z., Guo, L., Lei, X., Wang, J., Wang, M., Jin, Q., Cui, S.
Deposit date:2011-03-07
Release date:2011-08-10
Last modified:2015-05-06
Method:X-RAY DIFFRACTION (1.7001 Å)
Cite:Crystal Structures of Enterovirus 71 3C Protease Complexed with Rupintrivir Reveal the Roles of Catalytically Important Residues.
J.Virol., 85, 2011
3QZR
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HUMAN ENTEROVIRUS 71 3C PROTEASE MUTANT E71A IN COMPLEX WITH RUPINTRIVIR
Descriptor:3C protein, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER, 1,2-ETHANEDIOL
Authors:Wang, J., Fan, T., Yao, X., Wu, Z., Guo, L., Lei, X., Wang, J., Wang, M., Jin, Q., Cui, S.
Deposit date:2011-03-07
Release date:2011-08-10
Last modified:2015-05-06
Method:X-RAY DIFFRACTION (1.039 Å)
Cite:Crystal Structures of Enterovirus 71 3C Protease Complexed with Rupintrivir Reveal the Roles of Catalytically Important Residues.
J.Virol., 85, 2011
3R0F
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HUMAN ENTEROVIRUS 71 3C PROTEASE MUTANT H133G IN COMPLEX WITH RUPINTRIVIR
Descriptor:3C protein, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER, 1,2-ETHANEDIOL
Authors:Wang, J., Fan, T., Yao, X., Wu, Z., Guo, L., Lei, X., Wang, J., Wang, M., Jin, Q., Cui, S.
Deposit date:2011-03-08
Release date:2011-08-10
Last modified:2015-05-06
Method:X-RAY DIFFRACTION (1.3083 Å)
Cite:Crystal Structures of Enterovirus 71 3C Protease Complexed with Rupintrivir Reveal the Roles of Catalytically Important Residues.
J.Virol., 85, 2011
4LY6
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NUCLEOTIDE-INDUCED ASYMMETRY WITHIN ATPASE ACTIVATOR RING DRIVES S54-RNAP INTERACTION AND ATP HYDROLYSIS
Descriptor:Transcriptional regulator (NtrC family), [[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-tris(fluoranyl)beryllium, MAGNESIUM ION, ...
Authors:Sysoeva, T.A., Chowdhury, S., Guo, L., Nixon, B.T.
Deposit date:2013-07-30
Release date:2013-12-04
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Nucleotide-induced asymmetry within ATPase activator ring drives sigma 54-RNAP interaction and ATP hydrolysis.
Genes Dev., 27, 2013
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