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4LLW
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BU of 4llw by Molmil
Crystal structure of Pertuzumab Clambda Fab with variable domain redesign (VRD2) at 1.95A
Descriptor: SULFATE ION, light chain Clambda, mutated Pertuzumab Fab heavy chain
Authors:Pustilnik, A, Lewis, S.M, Wu, X, Sereno, A, Huang, F, Guntas, G, Leaver-Fay, A, Smith, E.M, Ho, C, Hansen-Estruch, C, Chamberlain, A.K, Truhlar, S.M, Kuhlman, B, Demarest, S.J, Atwell, S.
Deposit date:2013-07-09
Release date:2014-01-29
Last modified:2019-06-26
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface.
Nat.Biotechnol., 32, 2014
4LLD
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BU of 4lld by Molmil
Structure of wild-type IgG1 antibody heavy chain constant domain 1 and light chain lambda constant domain (IgG1 CH1:Clambda) at 1.19A
Descriptor: Ig gamma-1 chain C region, Ig lambda-2 chain C region
Authors:Pustilnik, A, Lewis, S.M, Wu, X, Sereno, A, Huang, F, Guntas, G, Leaver-Fay, A, Smith, E.M, Ho, C, Hansen-Estruch, C, Chamberlain, A.K, Truhlar, S.M, Kuhlman, B, Demarest, S.J, Atwell, S.
Deposit date:2013-07-09
Release date:2014-01-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.19 Å)
Cite:Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface.
Nat.Biotechnol., 32, 2014
4LLY
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BU of 4lly by Molmil
Crystal structure of Pertuzumab Clambda Fab with variable and constant domain redesigns (VRD2 and CRD2) at 1.6A
Descriptor: GLYCEROL, MAGNESIUM ION, light chain Clambda, ...
Authors:Pustilnik, A, Lewis, S.M, Wu, X, Sereno, A, Huang, F, Guntas, G, Leaver-Fay, A, Smith, E.M, Ho, C, Hansen-Estruch, C, Chamberlain, A.K, Truhlar, S.M, Kuhlman, B, Demarest, S.J, Atwell, S.
Deposit date:2013-07-09
Release date:2014-01-29
Last modified:2019-06-26
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface.
Nat.Biotechnol., 32, 2014
4LLQ
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BU of 4llq by Molmil
Structure of redesigned IgG1 first constant and lambda domains (CH1:Clambda constant redesign 2 beta, CRD2b) at 1.42A
Descriptor: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, mutated CH1, mutated light chain Clambda
Authors:Pustilnik, A, Lewis, S.M, Wu, X, Sereno, A, Huang, F, Guntas, G, Leaver-Fay, A, Smith, E.M, Ho, C, Hansen-Estruch, C, Chamberlain, A.K, Truhlar, S.M, Kuhlman, B, Demarest, S.J, Atwell, S.
Deposit date:2013-07-09
Release date:2014-01-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface.
Nat.Biotechnol., 32, 2014
4LLU
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BU of 4llu by Molmil
Structure of Pertuzumab Fab with light chain Clambda at 2.16A
Descriptor: ACETATE ION, Light chain CLAMBDA, PERTUZUMAB FAB Heavy chain, ...
Authors:Pustilnik, A, Lewis, S.M, Wu, X, Sereno, A, Huang, F, Guntas, G, Leaver-Fay, A, Smith, E.M, Ho, C, Hansen-Estruch, C, Chamberlain, A.K, Truhlar, S.M, Kuhlman, B, Demarest, S.J, Atwell, S.
Deposit date:2013-07-09
Release date:2014-01-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface.
Nat.Biotechnol., 32, 2014
4LLM
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BU of 4llm by Molmil
Structure of redesigned IgG1 first constant and lambda domains (CH1:Clambda constant redesign 1, CRD1) at 1.75A
Descriptor: Ig gamma-1 chain C region, Ig lambda-2 chain C region
Authors:Pustilnik, A, Lewis, S.M, Wu, X, Sereno, A, Huang, F, Guntas, G, Leaver-Fay, A, Smith, E.M, Ho, C, Hansen-Estruch, C, Chamberlain, A.K, Truhlar, S.M, Kuhlman, B, Demarest, S.J, Atwell, S.
Deposit date:2013-07-09
Release date:2014-01-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface.
Nat.Biotechnol., 32, 2014
4WF0
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BU of 4wf0 by Molmil
Crystal Structure of iLID - an Improved Light-Inducible Dimer
Descriptor: CHLORIDE ION, FLAVIN MONONUCLEOTIDE, NPH1-1
Authors:Hallett, R, Williams, T, Kuhlman, B.
Deposit date:2014-09-11
Release date:2014-12-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Engineering an improved light-induced dimer (iLID) for controlling the localization and activity of signaling proteins.
Proc.Natl.Acad.Sci.USA, 112, 2015
3HPI
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BU of 3hpi by Molmil
Crystal structure of maltose-binding protein mutant with bound sucrose
Descriptor: ACETATE ION, Maltose-binding periplasmic protein, ZINC ION, ...
Authors:Gould, A.D, Shilton, B.H.
Deposit date:2009-06-04
Release date:2010-02-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Studies of the maltose transport system reveal a mechanism for coupling ATP hydrolysis to substrate translocation without direct recognition of substrate.
J.Biol.Chem., 285, 2010
5KAY
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BU of 5kay by Molmil
Structure of Spelter bound to Zn2+
Descriptor: SODIUM ION, Spelter, ZINC ION
Authors:Guffy, S.L, Der, B.S, Kuhlman, B.
Deposit date:2016-06-02
Release date:2016-08-03
Last modified:2019-11-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Probing the minimal determinants of zinc binding with computational protein design.
Protein Eng.Des.Sel., 29, 2016

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