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3J45
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STRUCTURE OF A NON-TRANSLOCATING SECY PROTEIN CHANNEL WITH THE 70S RIBOSOME
Descriptor:Protein translocase subunit SecY, Preprotein translocase subunit SecE, Protein-export membrane protein SecG, ...
Authors:Menetret, J.F., Park, E., Gumbart, J.C., Ludtke, S.J., Li, W., Whynot, A., Rapoport, T.A., Akey, C.W.
Deposit date:2013-06-18
Release date:2013-10-23
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (9.5 Å)
Cite:Structure of the SecY channel during initiation of protein translocation.
Nature, 506, 2013
3J46
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STRUCTURE OF THE SECY PROTEIN TRANSLOCATION CHANNEL IN ACTION
Descriptor:Protein translocase subunit SecY, Preprotein translocase subunit SecE, Protein-export membrane protein SecG, ...
Authors:Akey, C.W., Park, E., Menetret, J.F., Gumbart, J.C., Ludtke, S.J., Li, W., Whynot, A., Rapoport, T.A.
Deposit date:2013-06-18
Release date:2013-10-23
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (10.1 Å)
Cite:Structure of the SecY channel during initiation of protein translocation.
Nature, 506, 2013
4LF0
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THE E142D MUTANT OF THE AMIDASE FROM GEOBACILLUS PALLIDUS
Descriptor:Aliphatic amidase
Authors:Sewell, B.T., Weber, B.W., Kimani, S.W., Cowan, D.A., Hunter, R., Venter, G.A., Gumbart, J.C., Thuku, R.N., Varsani, A.
Deposit date:2013-06-26
Release date:2013-08-21
Last modified:2014-02-12
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:The mechanism of the amidases: mutating the glutamate adjacent to the catalytic triad inactivates the enzyme due to substrate mispositioning.
J.Biol.Chem., 288, 2013
4V4N
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STRUCTURE OF THE METHANOCOCCUS JANNASCHII RIBOSOME-SECYEBETA CHANNEL COMPLEX
Descriptor:Preprotein translocase subunit SecE, Preprotein translocase subunit SecG, 50S ribosomal protein L39E, ...
Authors:Menetret, J.F., Park, E., Gumbart, J.C., Ludtke, S.J., Li, W., Whynot, A., Rapoport, T.A., Akey, C.W.
Deposit date:2013-06-17
Release date:2014-07-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Structure of the SecY channel during initiation of protein translocation.
Nature, 506, 2013
4V7I
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RIBOSOME-SECY COMPLEX.
Descriptor:5S ribosomal RNA, 23S ribosomal RNA, PREPROTEIN TRANSLOCASE SECY SUBUNIT, ...
Authors:Gumbart, J.C., Trabuco, L.G., Schreiner, E., Villa, E., Schulten, K.
Deposit date:2009-10-21
Release date:2014-07-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (9.6 Å)
Cite:Regulation of the protein-conducting channel by a bound ribosome.
Structure, 17, 2009
4EYY
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CRYSTAL STRUCTURE OF THE ICMR-ICMQ COMPLEX FROM LEGIONELLA PNEUMOPHILA
Descriptor:IcmR, IcmQ
Authors:Farelli, J.D., Gumbart, J., Akey, I.V., Amyot, W., Hempstead, A.D., Head, J.F., McKnight, C.J., Isberg, R.R., Akey, C.W.
Deposit date:2012-05-02
Release date:2013-05-22
Last modified:2014-07-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:IcmQ in the Type 4b secretion system contains an NAD+ binding domain.
Structure, 21, 2013
4EWL
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CRYSTAL STRUCTURE OF MSHB WITH GLYCEROL AND ACETATE BOUND IN THE ACTIVE SITE
Descriptor:1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, GLYCEROL, ...
Authors:Broadley, S.G., Sewell, B.T., Weber, B.W., Marakalala, M.J., Steenkamp, D.J.
Deposit date:2012-04-27
Release date:2012-09-26
Last modified:2012-11-21
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:A new crystal form of MshB from Mycobacterium tuberculosis with glycerol and acetate in the active site suggests the catalytic mechanism.
Acta Crystallogr.,Sect.D, 68, 2012
4GYL
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THE E142L MUTANT OF THE AMIDASE FROM GEOBACILLUS PALLIDUS SHOWING THE RESULT OF MICHAEL ADDITION OF ACRYLAMIDE AT THE ACTIVE SITE CYSTEINE
Descriptor:Aliphatic amidase, PROPIONAMIDE, CHLORIDE ION
Authors:Weber, B.W., Sewell, B.T., Kimani, S.W., Varsani, A., Cowan, D.A., Hunter, R.
Deposit date:2012-09-05
Release date:2013-08-21
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The mechanism of the amidases: mutating the glutamate adjacent to the catalytic triad inactivates the enzyme due to substrate mispositioning.
J.Biol.Chem., 288, 2013
4GYN
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THE E142L MUTANT OF THE AMIDASE FROM GEOBACILLUS PALLIDUS
Descriptor:Aliphatic amidase, CHLORIDE ION
Authors:Weber, B.W., Sewell, B.T., Kimani, S.W., Varsani, A., Cowan, D.A., Hunter, R.
Deposit date:2012-09-05
Release date:2013-08-21
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The mechanism of the amidases: mutating the glutamate adjacent to the catalytic triad inactivates the enzyme due to substrate mispositioning.
J.Biol.Chem., 288, 2013
4K3B
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THE CRYSTAL STRUCTURE OF BAMA FROM NEISSERIA GONORRHOEAE
Descriptor:Outer membrane protein assembly factor BamA
Authors:Noinaj, N., Lukacik, P., Chang, H., Easley, N., Buchanan, S.K.
Deposit date:2013-04-10
Release date:2013-09-04
Last modified:2013-10-02
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural insight into the biogenesis of beta-barrel membrane proteins.
Nature, 501, 2013
4K3C
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THE CRYSTAL STRUCTURE OF BAMA FROM HAEMOPHILUS DUCREYI LACKING POTRA DOMAINS 1-3
Descriptor:Outer membrane protein assembly factor BamA
Authors:Noinaj, N., Lukacik, P., Chang, H., Easley, N., Buchanan, S.K.
Deposit date:2013-04-10
Release date:2013-09-04
Last modified:2013-10-02
Method:X-RAY DIFFRACTION (2.913 Å)
Cite:Structural insight into the biogenesis of beta-barrel membrane proteins.
Nature, 501, 2013
4KZF
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THE MECHANISM OF THE AMIDASES: THE EFFECT OF THE MUTATION E142L IN THE AMIDASE FROM GEOBACILLUS PALLIDUS
Descriptor:Aliphatic amidase, CHLORIDE ION
Authors:Weber, B.W., Sewell, B.T., Kimani, S.W., Varsani, A., Cowan, D.A., Hunter, R.
Deposit date:2013-05-29
Release date:2013-08-21
Last modified:2014-02-12
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The mechanism of the amidases: mutating the glutamate adjacent to the catalytic triad inactivates the enzyme due to substrate mispositioning.
J.Biol.Chem., 288, 2013
4X0K
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ENGINEERED FAB FRAGMENT SPECIFIC FOR EYMPME (EE) PEPTIDE
Descriptor:Fab fragment heavy chain, Fab fragment light chain
Authors:Johnson, J.L., Lieberman, R.L.
Deposit date:2014-11-21
Release date:2015-04-08
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Structural and biophysical characterization of an epitope-specific engineered Fab fragment and complexation with membrane proteins: implications for co-crystallization.
Acta Crystallogr.,Sect.D, 71, 2015
4YS0
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CONFORMATIONAL CHANGES OF THE CLAMP OF THE PROTEIN TRANSLOCATION ATPASE SECA FROM THERMOTOGA MARITIMA
Descriptor:Protein translocase subunit SecA, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Chen, Y., Rapoport, T.A.
Deposit date:2015-03-16
Release date:2015-06-03
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.897 Å)
Cite:Conformational Changes of the Clamp of the Protein Translocation ATPase SecA.
J.Mol.Biol., 427, 2015
5IV8
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THE LPS TRANSPORTER LPTDE FROM KLEBSIELLA PNEUMONIAE, CORE COMPLEX
Descriptor:LPS biosynthesis protein, LPS-assembly lipoprotein LptE, (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE
Authors:Botos, I., McCarthy, J.G., Buchanan, S.K.
Deposit date:2016-03-20
Release date:2016-05-18
Last modified:2016-06-15
Method:X-RAY DIFFRACTION (2.938 Å)
Cite:Structural and Functional Characterization of the LPS Transporter LptDE from Gram-Negative Pathogens.
Structure, 24, 2016
5IV9
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THE LPS TRANSPORTER LPTDE FROM KLEBSIELLA PNEUMONIAE, FULL-LENGTH
Descriptor:LPS-assembly protein LptD, LPS-assembly lipoprotein LptE, (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE
Authors:Botos, I., McCarthy, J.G., Buchanan, S.K.
Deposit date:2016-03-20
Release date:2016-05-18
Last modified:2016-06-15
Method:X-RAY DIFFRACTION (4.369 Å)
Cite:Structural and Functional Characterization of the LPS Transporter LptDE from Gram-Negative Pathogens.
Structure, 24, 2016
5IVA
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THE LPS TRANSPORTER LPTDE FROM PSEUDOMONAS AERUGINOSA, CORE COMPLEX
Descriptor:LPS-assembly protein LptD, LPS-assembly lipoprotein LptE, (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE
Authors:Botos, I., Buchanan, S.K.
Deposit date:2016-03-20
Release date:2016-05-18
Last modified:2016-06-15
Method:X-RAY DIFFRACTION (2.988 Å)
Cite:Structural and Functional Characterization of the LPS Transporter LptDE from Gram-Negative Pathogens.
Structure, 24, 2016
5IXM
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THE LPS TRANSPORTER LPTDE FROM YERSINIA PESTIS, CORE COMPLEX
Descriptor:LPS-assembly protein LptD, LPS-assembly lipoprotein LptE, (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE
Authors:Botos, I., Mayclin, S.J., McCarthy, J.G., Buchanan, S.K.
Deposit date:2016-03-23
Release date:2016-05-18
Last modified:2016-06-15
Method:X-RAY DIFFRACTION (2.746 Å)
Cite:Structural and Functional Characterization of the LPS Transporter LptDE from Gram-Negative Pathogens.
Structure, 24, 2016
5VR2
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MOUSE MYOCILIN LEUCINE ZIPPER C-TERMINAL 7 HEPTAD REPEAT
Descriptor:Myocilin
Authors:Lieberman, R.L., Hill, S.E.
Deposit date:2017-05-10
Release date:2017-11-08
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.922 Å)
Cite:Structure and Misfolding of the Flexible Tripartite Coiled-Coil Domain of Glaucoma-Associated Myocilin.
Structure, 25, 2017