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5TE5
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CRYSTAL STRUCTURE OF BOS TAURUS OPSIN REGENERATED WITH 6-CARBON RING RETINAL CHROMOPHORE
Descriptor:Rhodopsin, (2E)-{(4E)-4-[(3E)-4-(2,6,6-trimethylcyclohex-1-en-1-yl)but-3-en-2-ylidene]cyclohex-2-en-1-ylidene}acetaldehyde
Authors:Gulati, S., Banerjee, S., Katayama, K., Kiser, P.D., Palczewski, K.
Deposit date:2016-09-20
Release date:2017-03-15
Last modified:2017-04-05
Method:X-RAY DIFFRACTION (4.01 Å)
Cite:Photocyclic behavior of rhodopsin induced by an atypical isomerization mechanism.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5TE3
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CRYSTAL STRUCTURE OF BOS TAURUS OPSIN AT 2.7 ANGSTROM
Descriptor:Rhodopsin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Gulati, S., Kiser, P.D., Palczewski, K.
Deposit date:2016-09-20
Release date:2017-03-15
Last modified:2017-04-05
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Photocyclic behavior of rhodopsin induced by an atypical isomerization mechanism.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6B20
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CRYSTAL STRUCTURE OF A COMPLEX BETWEEN G PROTEIN BETA GAMMA DIMER AND AN INHIBITORY NANOBODY REGULATOR
Descriptor:Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, Nanobody against G protein beta gamma dimer, ...
Authors:Gulati, S., Kiser, P.D., Palczewski, K.
Deposit date:2017-09-19
Release date:2018-05-30
Last modified:2018-08-15
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Targeting G protein-coupled receptor signaling at the G protein level with a selective nanobody inhibitor.
Nat Commun, 9, 2018
6MZB
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CRYO-EM STRUCTURE OF PHOSPHODIESTERASE 6
Descriptor:Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta, Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha, Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma, ...
Authors:Gulati, S., Palczewski, K.
Deposit date:2018-11-04
Release date:2019-03-06
Last modified:2019-03-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structure of phosphodiesterase 6 reveals insights into the allosteric regulation of type I phosphodiesterases.
Sci Adv, 5, 2019