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4CHE
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BU of 4che by Molmil
Crystal structure of the putative cap-binding domain of the PB2 subunit of Thogoto virus polymerase
Descriptor: POLYMERASE BASIC PROTEIN 2
Authors:Guilligay, D, Kadlec, J, Crepin, T, Lunardi, T, Bouvier, D, Kochs, G, Ruigrok, R.W.H, Cusack, S.
Deposit date:2013-12-01
Release date:2014-02-05
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Comparative Structural and Functional Analysis of Orthomyxovirus Polymerase CAP-Snatching Domains.
Plos One, 9, 2014
4CHC
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BU of 4chc by Molmil
Crystal structure of the N-terminal domain of the PA subunit of Thogoto virus polymerase (form 2)
Descriptor: POLYMERASE ACIDIC PROTEIN
Authors:Guilligay, D, Kadlec, J, Crepin, T, Lunardi, T, Bouvier, D, Kochs, G, Ruigrok, R.W.H, Cusack, S.
Deposit date:2013-12-01
Release date:2014-02-05
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Comparative Structural and Functional Analysis of Orthomyxovirus Polymerase CAP-Snatching Domains.
Plos One, 9, 2014
4CGS
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BU of 4cgs by Molmil
Crystal structure of the N-terminal domain of the PA subunit of Dhori virus polymerase
Descriptor: GLYCEROL, POLYMERASE SUBUNIT PA
Authors:Guilligay, D, Kadlec, J, Crepin, T, Lunardi, T, Bouvier, D, Kochs, G, Ruigrok, R.W.H, Cusack, S.
Deposit date:2013-11-26
Release date:2014-02-05
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Comparative Structural and Functional Analysis of Orthomyxovirus Polymerase CAP-Snatching Domains.
Plos One, 9, 2014
4CHF
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BU of 4chf by Molmil
Crystal structure of the putative cap-binding domain of the PB2 subunit of Thogoto virus polymerase (form 2)
Descriptor: POLYMERASE BASIC PROTEIN 2
Authors:Guilligay, D, Kadlec, J, Crepin, T, Lunardi, T, Bouvier, D, Kochs, G, Ruigrok, R.W.H, Cusack, S.
Deposit date:2013-12-01
Release date:2014-02-05
Method:X-RAY DIFFRACTION (3 Å)
Cite:Comparative Structural and Functional Analysis of Orthomyxovirus Polymerase CAP-Snatching Domains.
Plos One, 9, 2014
4CHD
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BU of 4chd by Molmil
Crystal structure of the '627' domain of the PB2 subunit of Thogoto virus polymerase
Descriptor: POLYMERASE ACIDIC PROTEIN
Authors:Guilligay, D, Kadlec, J, Crepin, T, Lunardi, T, Bouvier, D, Kochs, G, Ruigrok, R.W.H, Cusack, S.
Deposit date:2013-12-01
Release date:2014-02-05
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Comparative Structural and Functional Analysis of Orthomyxovirus Polymerase CAP-Snatching Domains.
Plos One, 9, 2014
4CGX
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BU of 4cgx by Molmil
Crystal structure of the N-terminal domain of the PA subunit of Thogoto virus polymerase (form 1)
Descriptor: POLYMERASE ACIDIC PROTEIN
Authors:Guilligay, D, Kadlec, J, Crepin, T, Lunardi, T, Bouvier, D, Kochs, G, Ruigrok, R.W.H, Cusack, S.
Deposit date:2013-11-27
Release date:2014-02-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Comparative Structural and Functional Analysis of Orthomyxovirus Polymerase CAP-Snatching Domains.
Plos One, 9, 2014
2VQZ
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BU of 2vqz by Molmil
Structure of the cap-binding domain of influenza virus polymerase subunit PB2 with bound m7GTP
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, POLYMERASE BASIC PROTEIN 2
Authors:Guilligay, D, Tarendeau, F, Resa-Infante, P, Coloma, R, Crepin, T, Sehr, P, Lewis, J, Ruigrok, R.W.H, Ortin, J, Hart, D.J, Cusack, S.
Deposit date:2008-03-21
Release date:2008-05-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Structural Basis for CAP Binding by Influenza Virus Polymerase Subunit Pb2.
Nat.Struct.Mol.Biol., 15, 2008
5EPI
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BU of 5epi by Molmil
CRYSTAL STRUCTURE OF INFLUENZA B POLYMERASE WITH BOUND 5' CRNA EXHIBITS A NOVEL DOMAIN ARRANGEMENT
Descriptor: CRNA 5' END, Polymerase acidic protein, Polymerase basic protein 2, ...
Authors:Guilligay, D, Cusack, S.
Deposit date:2015-11-11
Release date:2016-01-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Influenza Polymerase Can Adopt an Alternative Configuration Involving a Radical Repacking of PB2 Domains.
Mol.Cell, 61, 2016
5FMZ
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BU of 5fmz by Molmil
Crystal structure of Influenza B polymerase with bound 5' vRNA
Descriptor: 5'-R(*AP*GP*UP*AP*GP*UP*AP*AP*CP*AP*AP*GP)-3', POLYMERASE ACIDIC PROTEIN, POLYMERASE BASIC PROTEIN 2, ...
Authors:Guilligay, D, Cusack, S.
Deposit date:2015-11-10
Release date:2016-01-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Influenza Polymerase Can Adopt an Alternative Configuration Involving a Radical Repacking of Pb2 Domains.
Mol.Cell, 61, 2016
5FML
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BU of 5fml by Molmil
Crystal structure of the endonuclease from the PA subunit of influenza B virus bound to the PB2 subunit NLS peptide
Descriptor: GLYCEROL, MAGNESIUM ION, PA SUBUNIT OF INFLUENZA B POLYMERASE, ...
Authors:Guilligay, D, Gaudon, S, Cusack, S.
Deposit date:2015-11-06
Release date:2016-01-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Influenza Polymerase Can Adopt an Alternative Configuration Involving a Radical Repacking of Pb2 Domains.
Mol.Cell, 61, 2016
4WRT
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BU of 4wrt by Molmil
Crystal structure of Influenza B polymerase with bound vRNA promoter (form FluB2)
Descriptor: Influenza virus polymerase vRNA promoter 3' end, Influenza virus polymerase vRNA promoter 5' end, PA, ...
Authors:Reich, S, Guilligay, D, Pflug, A, Cusack, S.
Deposit date:2014-10-25
Release date:2014-11-19
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural insight into cap-snatching and RNA synthesis by influenza polymerase.
Nature, 516, 2014
7AEJ
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BU of 7aej by Molmil
Crystal structure of asymmetric HIV-1 gp41 containing all membrane anchors
Descriptor: 2H10, Envelope glycoprotein gp160,Envelope glycoprotein gp160
Authors:Caillat, C, Guilligay, D, Weissenhorn, W.
Deposit date:2020-09-17
Release date:2021-05-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structure of HIV-1 gp41 with its membrane anchors targeted by neutralizing antibodies.
Elife, 10, 2021
5MSG
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BU of 5msg by Molmil
Influenza B polymerase bound to vRNA promoter and capped RNA primer
Descriptor: PHOSPHATE ION, Polymerase acidic protein, Polymerase basic protein 2, ...
Authors:Cusack, S, Guilligay, D.
Deposit date:2017-01-04
Release date:2017-02-08
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:An in vitro fluorescence based study of initiation of RNA synthesis by influenza B polymerase.
Nucleic Acids Res., 45, 2017
4WSB
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BU of 4wsb by Molmil
Bat Influenza A polymerase with bound vRNA promoter
Descriptor: Influenza A polymerase vRNA promoter 3' end, Influenza A polymerase vRNA promoter 5' end, PHOSPHATE ION, ...
Authors:Cusack, S, Pflug, A, Guilligay, D, Reich, S.
Deposit date:2014-10-26
Release date:2014-11-19
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural insight into cap-snatching and RNA synthesis by influenza polymerase.
Nature, 516, 2014
4WSA
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BU of 4wsa by Molmil
Crystal structure of Influenza B polymerase bound to the vRNA promoter (FluB1 form)
Descriptor: Influenza B vRNA promoter 3' end, Influenza B vRNA promoter 5' end, PA, ...
Authors:Reich, S, Guilligay, D, Pflug, A, Cusack, S.
Deposit date:2014-10-26
Release date:2014-11-19
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural insight into cap-snatching and RNA synthesis by influenza polymerase.
Nature, 516, 2014
1UXE
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BU of 1uxe by Molmil
ADENOVIRUS AD37 FIBRE HEAD
Descriptor: ACETATE ION, FIBER PROTEIN, ZINC ION
Authors:Burmeister, W.P, Guilligay, D, Cusack, S, Wadell, G, Arnberg, N.
Deposit date:2004-02-24
Release date:2004-07-02
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Species D Adenovirus Fiber Knobs and Their Sialic Acid Binding Sites
J.Virol., 78, 2004
1UXB
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BU of 1uxb by Molmil
ADENOVIRUS AD19p FIBRE HEAD in complex with sialyl-lactose
Descriptor: ACETATE ION, FIBER PROTEIN, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose, ...
Authors:Burmeister, W.P, Guilligay, D, Cusack, S, Wadell, G, Arnberg, N.
Deposit date:2004-02-24
Release date:2004-07-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal Structure of Species D Adenovirus Fiber Knobs and Their Sialic Acid Binding Sites
J.Virol., 78, 2004
1UXA
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BU of 1uxa by Molmil
ADENOVIRUS AD37 FIBRE HEAD in complex with sialyl-lactose
Descriptor: ACETATE ION, FIBER PROTEIN, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose, ...
Authors:Burmeister, W.P, Guilligay, D, Cusack, S, Wadell, G, Arnberg, N.
Deposit date:2004-02-24
Release date:2004-07-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal Structure of Species D Adenovirus Fiber Knobs and Their Sialic Acid Binding Sites
J.Virol., 78, 2004
2VY7
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BU of 2vy7 by Molmil
The 627-domain from influenza A virus polymerase PB2 subunit
Descriptor: POLYMERASE BASIC PROTEIN 2
Authors:Tarendeau, F, Crepin, T, Guilligay, D, Ruigrok, R, Cusack, S, Hart, D.
Deposit date:2008-07-18
Release date:2008-09-09
Last modified:2012-06-06
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Host Determinant Residue Lysine 627 Lies on the Surface of a Discrete, Folded Domain of Influenza Virus Polymerase Pb2 Subunit
Plos Pathog., 4, 2008
2VY8
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BU of 2vy8 by Molmil
The 627-domain from influenza A virus polymerase PB2 subunit with Glu- 627
Descriptor: POLYMERASE BASIC PROTEIN 2
Authors:Tarendeau, F, Crepin, T, Guilligay, D, Ruigrok, R, Cusack, S, Hart, D.
Deposit date:2008-07-19
Release date:2008-09-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Host Determinant Residue Lysine 627 Lies on the Surface of a Discrete, Folded Domain of Influenza Virus Polymerase Pb2 Subunit
Plos Pathog., 4, 2008
2VY6
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BU of 2vy6 by Molmil
Two domains from the C-terminal region of influenza A virus polymerase PB2 subunit
Descriptor: POLYMERASE BASIC PROTEIN 2
Authors:Tarendeau, F, Crepin, T, Guilligay, D, Ruigrok, R, Cusack, S, Hart, D.
Deposit date:2008-07-18
Release date:2008-09-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Host Determinant Residue Lysine 627 Lies on the Surface of a Discrete, Folded Domain of Influenza Virus Polymerase Pb2 Subunit
Plos Pathog., 4, 2008
2GMO
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BU of 2gmo by Molmil
NMR-structure of an independently folded C-terminal domain of influenza polymerase subunit PB2
Descriptor: Polymerase basic protein 2
Authors:Boudet, J, Tarendeau, F, Guilligay, D, Mas, P, Bougault, C.M, Cusack, S, Simorre, J.-P, Hart, D.J.
Deposit date:2006-04-07
Release date:2007-02-27
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Structure and nuclear import function of the C-terminal domain of influenza virus polymerase PB2 subunit.
Nat.Struct.Mol.Biol., 14, 2007
2IYK
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BU of 2iyk by Molmil
Crystal structure of the UPF2-interacting domain of nonsense mediated mRNA decay factor UPF1
Descriptor: REGULATOR OF NONSENSE TRANSCRIPTS 1, ZINC ION
Authors:Kadlec, J, Guilligay, D, Ravelli, R.B, Cusack, S.
Deposit date:2006-07-18
Release date:2006-08-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Crystal Structure of the Upf2-Interacting Domain of Nonsense-Mediated Mrna Decay Factor Upf1.
RNA, 12, 2006
2JDQ
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BU of 2jdq by Molmil
C-terminal domain of influenza A virus polymerase PB2 subunit in complex with human importin alpha5
Descriptor: IMPORTIN ALPHA-1 SUBUNIT, POLYMERASE BASIC PROTEIN 2
Authors:Tarendeau, F, Guilligay, D, Mas, P, Boulo, S, Baudin, F, Ruigrok, R.W.H, Hart, D.J, Cusack, S.
Deposit date:2007-01-11
Release date:2007-02-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure and Nuclear Import Function of the C- Terminal Domain of Influenza Virus Polymerase Pb2 Subunit
Nat.Struct.Mol.Biol., 14, 2007
2WGU
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BU of 2wgu by Molmil
Structure of human adenovirus serotype 37 fibre head in complex with a sialic acid derivative, O-Methyl 5-N- methoxycarbonyl -3,5-dideoxy- D-glycero-a-D-galacto-2-nonulopyranosylonic acid
Descriptor: 3,5-dideoxy-5-[(methoxycarbonyl)amino]-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid, FIBER PROTEIN, ZINC ION
Authors:Johansson, S, Nilsson, E, Qian, W, Guilligay, D, Crepin, T, Cusack, S, Arnberg, N, Elofsson, M.
Deposit date:2009-04-27
Release date:2009-11-24
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Design, Synthesis, and Evaluation of N-Acyl Modified Sialic Acids as Inhibitors of Adenoviruses Causing Epidemic Keratoconjunctivitis.
J.Med.Chem., 52, 2009

 

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