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4R32
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BU of 4r32 by Molmil
Crystal Structure Analysis of Pyk2 and Paxillin LD motifs
Descriptor: Paxillin, Protein-tyrosine kinase 2-beta
Authors:Vanarotti, M, Miller, D.J, Guibao, C.D, Nourse, A, Zheng, J.J.
Deposit date:2014-08-13
Release date:2014-09-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.505 Å)
Cite:Structural and Mechanistic Insights into the Interaction between Pyk2 and Paxillin LD Motifs.
J.Mol.Biol., 426, 2014
2JX0
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BU of 2jx0 by Molmil
The paxillin-binding domain (PBD) of G Protein Coupled Receptor (GPCR)-kinase (GRK) interacting protein 1 (GIT1)
Descriptor: ARF GTPase-activating protein GIT1
Authors:Zhang, Z, Guibao, C.D, Simmerman, J.A, Zheng, J.
Deposit date:2007-11-01
Release date:2008-04-29
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:GIT1 paxillin-binding domain is a four-helix bundle, and it binds to both paxillin LD2 and LD4 motifs.
J.Biol.Chem., 283, 2008
3U3F
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BU of 3u3f by Molmil
Structural basis for the interaction of Pyk2 PAT domain with paxillin LD motifs
Descriptor: Paxillin LD2 peptide, Protein-tyrosine kinase 2-beta
Authors:Vanarotti, M, Miller, D.J, Guibao, C.C, Zheng, J.J.
Deposit date:2011-10-05
Release date:2012-10-24
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.101 Å)
Cite:Structural and Mechanistic Insights into the Interaction between Pyk2 and Paxillin LD Motifs.
J.Mol.Biol., 426, 2014
2LK4
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BU of 2lk4 by Molmil
Structural and mechanistic insights into the interaction between PAT Pyk2 and Paxillin LD motif
Descriptor: Protein-tyrosine kinase 2-beta
Authors:Vanarotti, M, Miller, D, Guibao, C, Zheng, J.
Deposit date:2011-10-04
Release date:2012-10-10
Last modified:2014-12-31
Method:SOLUTION NMR
Cite:Structural and Mechanistic Insights into the Interaction between Pyk2 and Paxillin LD Motifs.
J.Mol.Biol., 426, 2014
5W93
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BU of 5w93 by Molmil
p130Cas complex with paxillin LD1
Descriptor: Breast cancer anti-estrogen resistance protein 1, Paxillin
Authors:Miller, D.J, Zheng, J.J.
Deposit date:2017-06-22
Release date:2017-09-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Structural and functional insights into the interaction between the Cas family scaffolding protein p130Cas and the focal adhesion-associated protein paxillin.
J. Biol. Chem., 292, 2017
6CKV
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BU of 6ckv by Molmil
Solution NMR structure of human BOK
Descriptor: Bcl-2-related ovarian killer protein
Authors:Grace, C.R, Zheng, J, Moldoveanu, T.
Deposit date:2018-03-01
Release date:2018-05-09
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Intrinsic Instability of BOK Enables Membrane Permeabilization in Apoptosis.
Cell Rep, 23, 2018
6D74
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BU of 6d74 by Molmil
Direct Activation of the Executioner Domain of MLKL by a Select Repertoire of Inositol Phosphates
Descriptor: Mixed lineage kinase domain-like protein
Authors:Royappa, G.C, McNamara, D.E, Moldoveanu, T.
Deposit date:2018-04-24
Release date:2019-05-15
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Direct Activation of Human MLKL by a Select Repertoire of Inositol Phosphate Metabolites.
Cell Chem Biol, 26, 2019
7M5C
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BU of 7m5c by Molmil
Crystal Structure of human BAK in complex with WT BAK BH3 peptide
Descriptor: Bcl-2 homologous antagonist/killer, COPPER (II) ION, SULFATE ION
Authors:Singh, G, Aggarwal, A, Moldoveanu, T.
Deposit date:2021-03-23
Release date:2022-01-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.06 Å)
Cite:Structural basis of BAK activation in mitochondrial apoptosis initiation.
Nat Commun, 13, 2022
7M5B
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BU of 7m5b by Molmil
Crystal Structure of human BAK in complex with M3W5_BID
Descriptor: BH3-interacting domain death agonist p15, Bcl-2 homologous antagonist/killer, COPPER (II) ION
Authors:Singh, G, Aggarwal, A, Moldoveanu, T.
Deposit date:2021-03-23
Release date:2022-01-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural basis of BAK activation in mitochondrial apoptosis initiation.
Nat Commun, 13, 2022
7M5A
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BU of 7m5a by Molmil
Crystal Structure of human BAK in complex with W3W5_BID
Descriptor: BH3-interacting domain death agonist p15, Bcl-2 homologous antagonist/killer
Authors:Singh, G, Aggarwal, A, Moldoveanu, T.
Deposit date:2021-03-23
Release date:2022-01-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural basis of BAK activation in mitochondrial apoptosis initiation.
Nat Commun, 13, 2022
4XEK
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BU of 4xek by Molmil
Pyk2-FAT domain in complex with leupaxin LD4 motif
Descriptor: 19-mer peptide containing Leupaxin LD4 motif, Protein-tyrosine kinase 2-beta
Authors:Miller, D.J.
Deposit date:2014-12-24
Release date:2015-12-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.793 Å)
Cite:Structural Basis for the Interaction between Pyk2-FAT Domain and Leupaxin LD Repeats.
Biochemistry, 55, 2016
4XEV
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BU of 4xev by Molmil
Fusion of Pyk2-FAT domain with Leupaxin LD1 motif, complexed with Leupaxin LD4 peptide
Descriptor: 19-mer peptide containing Leupaxin LD4 motif, Fusion protein of Protein-tyrosine kinase 2-beta FAT domain and Leupaxin LD1 motif
Authors:Miller, D.J.
Deposit date:2014-12-24
Release date:2015-12-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.0073 Å)
Cite:Structural Basis for the Interaction between Pyk2-FAT Domain and Leupaxin LD Repeats.
Biochemistry, 55, 2016
4XEF
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BU of 4xef by Molmil
Pyk2-FAT complexed with Leupaxin LD motif LD1
Descriptor: 20-mer peptide containing LD1 motif of leupaxin, Protein-tyrosine kinase 2-beta
Authors:Miller, D.J.
Deposit date:2014-12-23
Release date:2015-12-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for the Interaction between Pyk2-FAT Domain and Leupaxin LD Repeats.
Biochemistry, 55, 2016
2MAH
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BU of 2mah by Molmil
Solution structure of Smoothened
Descriptor: Protein smoothened
Authors:Rana, R, Lee, H, Zheng, J.J.
Deposit date:2013-07-09
Release date:2014-03-05
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural insights into the role of the Smoothened cysteine-rich domain in Hedgehog signalling.
Nat Commun, 4, 2013
2HRJ
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BU of 2hrj by Molmil
NMR solution structure of the F2 subdomain of talin
Descriptor: Talin-1
Authors:Liu, G, Arroyo, M.M, Zheng, J.
Deposit date:2006-07-20
Release date:2008-04-29
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Structural characterization of the talin F2 FERM subdomain with Coenzyme A and PI(4,5)P2
To be Published

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PDB entries from 2024-04-24

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