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3TWQ
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BU of 3twq by Molmil
Crystal structure of ARC4 from human Tankyrase 2 (apo form)
Descriptor: GLYCEROL, SULFATE ION, Tankyrase-2
Authors:Guettler, S, Sicheri, F.
Deposit date:2011-09-22
Release date:2011-12-07
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.151 Å)
Cite:Structural basis and sequence rules for substrate recognition by tankyrase explain the basis for cherubism disease.
Cell(Cambridge,Mass.), 147, 2011
3TWW
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BU of 3tww by Molmil
Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human LNPEP (chimeric peptide)
Descriptor: SULFATE ION, Tankyrase-2, human LNPEP
Authors:Guettler, S, Sicheri, F.
Deposit date:2011-09-22
Release date:2011-12-07
Last modified:2011-12-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis and sequence rules for substrate recognition by tankyrase explain the basis for cherubism disease.
Cell(Cambridge,Mass.), 147, 2011
3TWS
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BU of 3tws by Molmil
Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human TERF1 (chimeric peptide)
Descriptor: 1,2-ETHANEDIOL, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, HEXAETHYLENE GLYCOL, ...
Authors:Guettler, S, Sicheri, F.
Deposit date:2011-09-22
Release date:2011-12-07
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis and sequence rules for substrate recognition by tankyrase explain the basis for cherubism disease.
Cell(Cambridge,Mass.), 147, 2011
3TWV
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BU of 3twv by Molmil
Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human NUMA1 (chimeric peptide)
Descriptor: 1,2-ETHANEDIOL, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, SULFATE ION, ...
Authors:Guettler, S, Sicheri, F.
Deposit date:2011-09-22
Release date:2011-12-07
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Structural basis and sequence rules for substrate recognition by tankyrase explain the basis for cherubism disease.
Cell(Cambridge,Mass.), 147, 2011
3TWR
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BU of 3twr by Molmil
Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human 3BP2
Descriptor: 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, SH3 domain-binding protein 2, SULFATE ION, ...
Authors:Guettler, S, Sicheri, F.
Deposit date:2011-09-22
Release date:2011-12-07
Last modified:2011-12-28
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural basis and sequence rules for substrate recognition by tankyrase explain the basis for cherubism disease.
Cell(Cambridge,Mass.), 147, 2011
3TWX
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BU of 3twx by Molmil
Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human FNBP1 (chimeric peptide)
Descriptor: 1,2-ETHANEDIOL, HEXAETHYLENE GLYCOL, SULFATE ION, ...
Authors:Guettler, S, Sicheri, F.
Deposit date:2011-09-22
Release date:2011-12-07
Last modified:2011-12-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis and sequence rules for substrate recognition by tankyrase explain the basis for cherubism disease.
Cell(Cambridge,Mass.), 147, 2011
3TWT
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BU of 3twt by Molmil
Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human MCL1 (chimeric peptide)
Descriptor: 1,2-ETHANEDIOL, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, NONAETHYLENE GLYCOL, ...
Authors:Guettler, S, Sicheri, F.
Deposit date:2011-09-22
Release date:2011-12-07
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural basis and sequence rules for substrate recognition by tankyrase explain the basis for cherubism disease.
Cell(Cambridge,Mass.), 147, 2011
3TWU
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BU of 3twu by Molmil
Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human MCL1
Descriptor: Induced myeloid leukemia cell differentiation protein Mcl-1, Tankyrase-2
Authors:Guettler, S, Sicheri, F.
Deposit date:2011-09-22
Release date:2011-12-07
Last modified:2011-12-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis and sequence rules for substrate recognition by tankyrase explain the basis for cherubism disease.
Cell(Cambridge,Mass.), 147, 2011
5JRT
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BU of 5jrt by Molmil
Crystal structure of the human Tankyrase 2 (TNKS2) SAM domain (DH902/924RE)
Descriptor: Tankyrase-2
Authors:Guettler, S, Mariotti, L, Cronin, N.
Deposit date:2016-05-06
Release date:2016-08-03
Last modified:2016-08-17
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Tankyrase Requires SAM Domain-Dependent Polymerization to Support Wnt-beta-Catenin Signaling.
Mol.Cell, 63, 2016
8ALY
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BU of 8aly by Molmil
Cryo-EM structure of human tankyrase 2 SAM-PARP filament (G1032W mutant)
Descriptor: Poly [ADP-ribose] polymerase tankyrase-2, ZINC ION
Authors:Mariotti, L, Inian, O, Desfosses, A, Beuron, F, Morris, E.P, Guettler, S.
Deposit date:2022-08-01
Release date:2022-11-16
Last modified:2022-12-14
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Structural basis of tankyrase activation by polymerization.
Nature, 612, 2022
2V52
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BU of 2v52 by Molmil
Structure of MAL-RPEL2 complexed to G-actin
Descriptor: ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Mouilleron, S, Guettler, S, Langer, C.A, Treisman, R, McDonald, N.Q.
Deposit date:2008-10-01
Release date:2008-11-25
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Molecular basis for G-actin binding to RPEL motifs from the serum response factor coactivator MAL.
EMBO J., 27, 2008
2V51
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BU of 2v51 by Molmil
Structure of MAL-RPEL1 complexed to actin
Descriptor: ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Mouilleron, S, Guettler, S, Langer, C.A, Treisman, R, McDonald, N.Q.
Deposit date:2008-10-01
Release date:2008-11-25
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Molecular basis for G-actin binding to RPEL motifs from the serum response factor coactivator MAL.
EMBO J., 27, 2008
2YJF
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BU of 2yjf by Molmil
Oligomeric assembly of actin bound to MRTF-A
Descriptor: ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Mouilleron, S, Langer, C.A, Guettler, S, McDonald, N.Q, Treisman, R.
Deposit date:2011-05-19
Release date:2011-07-06
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of a pentavalent G-actin*MRTF-A complex reveals how G-actin controls nucleocytoplasmic shuttling of a transcriptional coactivator.
Sci Signal, 4, 2011
2YJE
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BU of 2yje by Molmil
Oligomeric assembly of actin bound to MRTF-A
Descriptor: ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Mouilleron, S, Langer, C.A, Guettler, S, McDonald, N.Q, Treisman, R.
Deposit date:2011-05-19
Release date:2011-07-06
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of a pentavalent G-actin*MRTF-A complex reveals how G-actin controls nucleocytoplasmic shuttling of a transcriptional coactivator.
Sci Signal, 4, 2011
6BXI
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BU of 6bxi by Molmil
X-ray crystal structure of NDR1 kinase domain
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase 38
Authors:Xiong, S, Sicheri, F.
Deposit date:2017-12-18
Release date:2018-08-29
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis for Auto-Inhibition of the NDR1 Kinase Domain by an Atypically Long Activation Segment.
Structure, 26, 2018
5TWH
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BU of 5twh by Molmil
human MOB1A bound to MST1 phosphorylated T367 peptide
Descriptor: MOB kinase activator 1A, T367 peptide, ZINC ION
Authors:Xiong, S, Sicheri, F.
Deposit date:2016-11-13
Release date:2017-04-12
Last modified:2017-06-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:MOB1 Mediated Phospho-recognition in the Core Mammalian Hippo Pathway.
Mol. Cell Proteomics, 16, 2017
5TWG
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BU of 5twg by Molmil
human MOB1A bound to human MST1 phosphorylated T353 peptide
Descriptor: MOB kinase activator 1A, T353 peptide, ZINC ION
Authors:Xiong, S, Sicheri, F.
Deposit date:2016-11-13
Release date:2017-04-12
Last modified:2017-06-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:MOB1 Mediated Phospho-recognition in the Core Mammalian Hippo Pathway.
Mol. Cell Proteomics, 16, 2017
5TWF
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BU of 5twf by Molmil
Regulation of protein interactions by MOB1 phosphorylation
Descriptor: MOB kinase activator 1A, ZINC ION
Authors:Xiong, S, Sicheri, F.
Deposit date:2016-11-13
Release date:2017-04-12
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.136 Å)
Cite:Regulation of Protein Interactions by Mps One Binder (MOB1) Phosphorylation.
Mol. Cell Proteomics, 16, 2017
5JU5
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BU of 5ju5 by Molmil
Crystal structure of the human Tankyrase 1 (TNKS) SAM domain (D1055R), crystal form 1
Descriptor: Tankyrase-1
Authors:Guetter, S, Mariotti, L, Cronin, N.
Deposit date:2016-05-10
Release date:2016-08-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Tankyrase Requires SAM Domain-Dependent Polymerization to Support Wnt-beta-Catenin Signaling.
Mol.Cell, 63, 2016
5JTI
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BU of 5jti by Molmil
Crystal structure of the human Tankyrase 1 (TNKS) SAM domain (D1055R), crystal form 2
Descriptor: Tankyrase-1
Authors:Guetter, S, Mariotti, L, Cronin, N.
Deposit date:2016-05-09
Release date:2016-08-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Tankyrase Requires SAM Domain-Dependent Polymerization to Support Wnt-beta-Catenin Signaling.
Mol.Cell, 63, 2016
1OPK
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BU of 1opk by Molmil
Structural basis for the auto-inhibition of c-Abl tyrosine kinase
Descriptor: 6-(2,6-DICHLOROPHENYL)-2-{[3-(HYDROXYMETHYL)PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE, GLYCEROL, MYRISTIC ACID, ...
Authors:Nagar, B, Hantschel, O, Young, M.A, Scheffzek, K, Veach, D, Bornmann, W, Clarkson, B, Superti-Furga, G, Kuriyan, J.
Deposit date:2003-03-06
Release date:2003-04-08
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for the autoinhibition of c-Abl tyrosine kinase
Cell(Cambridge,Mass.), 112, 2003
1OPJ
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BU of 1opj by Molmil
Structural basis for the auto-inhibition of c-Abl tyrosine kinase
Descriptor: 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, CHLORIDE ION, MYRISTIC ACID, ...
Authors:Nagar, B, Hantschel, O, Young, M.A, Scheffzek, K, Veach, D, Bornmann, W, Clarkson, B, Superti-Furga, G, Kuriyan, J.
Deposit date:2003-03-06
Release date:2003-04-08
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural basis for the autoinhibition of c-Abl tyrosine kinase
Cell(Cambridge,Mass.), 112, 2003
1OPL
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BU of 1opl by Molmil
Structural basis for the auto-inhibition of c-Abl tyrosine kinase
Descriptor: 6-(2,6-DICHLOROPHENYL)-2-{[3-(HYDROXYMETHYL)PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE, MYRISTIC ACID, proto-oncogene tyrosine-protein kinase
Authors:Nagar, B, Hantschel, O, Young, M.A, Scheffzek, K, Veach, D, Bornmann, W, Clarkson, B, Superti-Furga, G, Kuriyan, J.
Deposit date:2003-03-06
Release date:2003-04-08
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.42 Å)
Cite:Structural basis for the autoinhibition of c-Abl tyrosine kinase
Cell(Cambridge,Mass.), 112, 2003

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