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5MIM
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Xray structure of human furin bound with the 2,5-dideoxystreptamine derived small molecule inhibitor 1n
Descriptor: 1-[(1~{R},2~{R},4~{S},5~{S})-2,4-bis(4-carbamimidamidophenoxy)-5-[(4-carbamimidamidophenyl)amino]cyclohexyl]guanidine, CALCIUM ION, CHLORIDE ION, ...
Authors:Dahms, S.O, Guan-Sheng, J, Than, M.E.
Deposit date:2016-11-28
Release date:2017-05-10
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Studies Revealed Active Site Distortions of Human Furin by a Small Molecule Inhibitor.
ACS Chem. Biol., 12, 2017

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