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2V8N
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BU of 2v8n by Molmil
Wild-type Structure of Lactose Permease
Descriptor: LACTOSE PERMEASE
Authors:Guan, L, Mirza, O, Verner, G, Iwata, S, Kaback, H.R.
Deposit date:2007-08-09
Release date:2007-09-11
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural Determination of Wild-Type Lactose Permease.
Proc.Natl.Acad.Sci.USA, 104, 2007
7L16
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BU of 7l16 by Molmil
Crystal structure of sugar-bound melibiose permease MelB
Descriptor: Melibiose carrier protein, dodecyl 6-O-alpha-D-galactopyranosyl-beta-D-glucopyranoside
Authors:Guan, L.
Deposit date:2020-12-14
Release date:2021-08-04
Last modified:2021-08-25
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:X-ray crystallography reveals molecular recognition mechanism for sugar binding in a melibiose transporter MelB.
Commun Biol, 4, 2021
7L17
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BU of 7l17 by Molmil
Crystal structure of sugar-bound melibiose permease MelB
Descriptor: 4-nitrophenyl alpha-D-galactopyranoside, Melibiose carrier protein
Authors:Guan, L.
Deposit date:2020-12-14
Release date:2021-08-04
Last modified:2021-08-25
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:X-ray crystallography reveals molecular recognition mechanism for sugar binding in a melibiose transporter MelB.
Commun Biol, 4, 2021
8T60
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BU of 8t60 by Molmil
CryoEM structure of an inward-facing MelBSt at a Na(+)-bound and sugar low-affinity conformation
Descriptor: Melibiose permease, NabFab_H Chain, NabFab_L Chain, ...
Authors:Guan, L.
Deposit date:2023-06-14
Release date:2024-02-28
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Mobile barrier mechanisms for Na + -coupled symport in an MFS sugar transporter.
Elife, 12, 2024
6PA0
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BU of 6pa0 by Molmil
Structure of the G77A mutant in Sodium Chloride
Descriptor: Antibody HEAVY fragment, Antibody LIGHT fragment, DIACYL GLYCEROL, ...
Authors:Cuello, L.G, Guan, L.
Deposit date:2019-06-11
Release date:2019-08-07
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure, function, and ion-binding properties of a K+channel stabilized in the 2,4-ion-bound configuration.
Proc.Natl.Acad.Sci.USA, 116, 2019
2Y5Y
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BU of 2y5y by Molmil
Crystal structure of LacY in complex with an affinity inactivator
Descriptor: 2-sulfanylethyl beta-D-galactopyranoside, BARIUM ION, LACTOSE PERMEASE
Authors:Chaptal, V, Kwon, S, Sawaya, M.R, Guan, L, Kaback, H.R, Abramson, J.
Deposit date:2011-01-19
Release date:2011-06-15
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.38 Å)
Cite:Crystal Structure of Lactose Permease in Complex with an Affinity Inactivator Yields Unique Insight Into Sugar Recognition.
Proc.Natl.Acad.Sci.USA, 108, 2011
2CFP
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BU of 2cfp by Molmil
Sugar Free Lactose Permease at acidic pH
Descriptor: LACTOSE PERMEASE, MERCURY (II) ION
Authors:Mirza, O, Guan, L, Verner, G, Iwata, S, Kaback, H.R.
Deposit date:2006-02-22
Release date:2006-03-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural Evidence for Induced Fit and a Mechanism for Sugar/H(+) Symport in Lacy.
Embo J., 25, 2006
2CFQ
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BU of 2cfq by Molmil
Sugar Free Lactose Permease at neutral pH
Descriptor: LACTOSE PERMEASE, MERCURY (II) ION
Authors:Mirza, O, Guan, L, Verner, G, Iwata, S, Kaback, H.R.
Deposit date:2006-02-22
Release date:2006-03-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural Evidence for Induced Fit and a Mechanism for Sugar/H(+) Symport in Lacy.
Embo J., 25, 2006
4QFV
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BU of 4qfv by Molmil
Crystal structure of a unique ankyrin
Descriptor: ACETATE ION, ANK-N5C-281
Authors:Ethayathulla, A.S, Tikhonova, E.B, Guan, L.
Deposit date:2014-05-21
Release date:2015-05-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:A transcription blocker isolated from a designed repeat protein combinatorial library by in vivo functional screen.
Sci Rep, 5, 2015
6NFV
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BU of 6nfv by Molmil
Structure of the KcsA-G77C mutant or the 2,4-ion bound configuration of a K+ channel selectivity filter.
Descriptor: (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, NONAN-1-OL, POTASSIUM ION, ...
Authors:Tilegenova, C, Cortes, D.M, Jahovic, N, Hardy, E, Parameswaran, H, Guan, L, Cuello, L.G.
Deposit date:2018-12-20
Release date:2019-08-07
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Structure, function, and ion-binding properties of a K+channel stabilized in the 2,4-ion-bound configuration.
Proc.Natl.Acad.Sci.USA, 116, 2019
6NFU
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BU of 6nfu by Molmil
Structure of the KcsA-G77A mutant or the 2,4-ion bound configuration of a K+ channel selectivity filter.
Descriptor: (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, NONAN-1-OL, POTASSIUM ION, ...
Authors:Tilegenova, C, Cortes, D.M, Jahovic, N, Hardy, E, Parameswaran, H, Guan, L, Cuello, L.G.
Deposit date:2018-12-20
Release date:2019-08-07
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structure, function, and ion-binding properties of a K+channel stabilized in the 2,4-ion-bound configuration.
Proc.Natl.Acad.Sci.USA, 116, 2019
4M64
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BU of 4m64 by Molmil
3D crystal structure of Na+/melibiose symporter of Salmonella typhimurium
Descriptor: Melibiose carrier protein
Authors:Ethayathulla, A.S, Guan, L.
Deposit date:2013-08-08
Release date:2014-01-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Structure-based mechanism for Na(+)/melibiose symport by MelB.
Nat Commun, 5, 2014
4O60
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BU of 4o60 by Molmil
Structure of ankyrin repeat protein
Descriptor: ANK-N5C-317
Authors:Ethayathulla, A.S, Guan, L.
Deposit date:2013-12-20
Release date:2015-03-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:A transcription blocker isolated from a designed repeat protein combinatorial library by in vivo functional screen.
Sci Rep, 5, 2015
3WI7
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BU of 3wi7 by Molmil
Crystal Structure of the Novel Haloalkane Dehalogenase DatA from Agrobacterium tumefaciens C58
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL, Haloalkane dehalogenase
Authors:Guan, L.J, Yabuki, H, Okai, M, Ohtsuka, J, Tanokura, M.
Deposit date:2013-09-06
Release date:2014-07-23
Last modified:2022-08-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of the novel haloalkane dehalogenase DatA from Agrobacterium tumefaciens C58 reveals a special halide-stabilizing pair and enantioselectivity mechanism.
Appl.Microbiol.Biotechnol., 98, 2014
3WIB
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BU of 3wib by Molmil
Crystal structure of Y109W Mutant Haloalkane Dehalogenase DatA from Agrobacterium tumefaciens C58
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Haloalkane dehalogenase
Authors:Guan, L.J, Yabuki, H, Okai, M, Ohtsuka, J, Tanokura, M.
Deposit date:2013-09-09
Release date:2014-07-23
Last modified:2022-08-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of the novel haloalkane dehalogenase DatA from Agrobacterium tumefaciens C58 reveals a special halide-stabilizing pair and enantioselectivity mechanism.
Appl.Microbiol.Biotechnol., 98, 2014
5B7J
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BU of 5b7j by Molmil
Structure model of Sap1-DNA complex
Descriptor: DNA (5'-D(*AP*AP*TP*AP*TP*TP*GP*TP*TP*TP*TP*G)-3'), DNA (5'-D(*CP*AP*AP*AP*AP*CP*AP*AP*TP*AP*TP*T)-3'), Switch-activating protein 1
Authors:Jin, C, Hu, Y, Ding, J, Zhang, Y.
Deposit date:2016-06-07
Release date:2017-02-22
Last modified:2017-05-24
Method:SOLUTION NMR
Cite:Sap1 is a replication-initiation factor essential for the assembly of pre-replicative complex in the fission yeast Schizosaccharomyces pombe
J. Biol. Chem., 292, 2017
5JDK
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BU of 5jdk by Molmil
Crystal structure of the DNA binding domain of Sap1 in fission yeast S.pombe
Descriptor: GLYCEROL, Switch-activating protein 1
Authors:He, P, Wang, T.
Deposit date:2016-04-17
Release date:2017-02-22
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (0.998 Å)
Cite:Sap1 is a replication-initiation factor essential for the assembly of pre-replicative complex in the fission yeast Schizosaccharomyces pombe.
J. Biol. Chem., 292, 2017
8IY0
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BU of 8iy0 by Molmil
Structure of Acb2 complexed with cAAA
Descriptor: [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] dihydrogen phosphate, p26
Authors:Cao, X.L, Xiao, Y, Feng, Y.
Deposit date:2023-04-03
Release date:2024-02-07
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Phage anti-CBASS protein simultaneously sequesters cyclic trinucleotides and dinucleotides.
Mol.Cell, 84, 2024
8IY2
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BU of 8iy2 by Molmil
Structure of Acb2 complexed with 3',3'-cGAMP and cAAA
Descriptor: 1,2-ETHANEDIOL, GUANOSINE-3'-MONOPHOSPHATE, [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] dihydrogen phosphate, ...
Authors:Cao, X.L, Xiao, Y, Feng, Y.
Deposit date:2023-04-03
Release date:2024-02-07
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Phage anti-CBASS protein simultaneously sequesters cyclic trinucleotides and dinucleotides.
Mol.Cell, 84, 2024
8IXZ
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BU of 8ixz by Molmil
Structure of Acb2 complexed with 3',2'-cGAMP
Descriptor: 3'2'-cGAMP, p26
Authors:Cao, X.L, Xiao, Y, Feng, Y.
Deposit date:2023-04-03
Release date:2024-02-07
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Phage anti-CBASS protein simultaneously sequesters cyclic trinucleotides and dinucleotides.
Mol.Cell, 84, 2024
8IY1
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BU of 8iy1 by Molmil
Structure of Acb2 complexed with cAAG
Descriptor: GUANOSINE-3'-MONOPHOSPHATE, [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] dihydrogen phosphate, p26
Authors:Cao, X.L, Xiao, Y, Feng, Y.
Deposit date:2023-04-03
Release date:2024-02-07
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Phage anti-CBASS protein simultaneously sequesters cyclic trinucleotides and dinucleotides.
Mol.Cell, 84, 2024
8J8O
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BU of 8j8o by Molmil
Structure of Acb2 complexed with 2',3'-cGAMP
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, cGAMP, ...
Authors:Cao, X.L, Xiao, Y, Feng, Y.
Deposit date:2023-05-02
Release date:2024-02-07
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Phage anti-CBASS protein simultaneously sequesters cyclic trinucleotides and dinucleotides.
Mol.Cell, 84, 2024
4K27
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BU of 4k27 by Molmil
Myotonic Dystrophy Type 2 RNA: Structural Studies and Designed Small Molecules that Modulate RNA Function
Descriptor: CHLORIDE ION, MAGNESIUM ION, Myotonic Dystrophy Type 2 RNA
Authors:Park, H, Lohman, J, Disney, M.D.
Deposit date:2013-04-08
Release date:2013-11-27
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Myotonic Dystrophy Type 2 RNA: Structural Studies and Designed Small Molecules that Modulate RNA Function
ACS CHEM.BIOL., 2013

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