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1NL4
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Crystal Structure of Rat Farnesyl Transferase in Complex With A Potent Biphenyl Inhibitor
Descriptor: 4-[(3-CYANO-BENZYL)-(3-METHYL-3H-IMIDAZOL-4-YLMETHYL)-AMINO]-2-NAPHTHALEN-1-YL-BENZONITRILE, ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID, Protein farnesyltransferase alpha subunit, ...
Authors:Curtin, M.L, Florjancic, A.S, Cohen, J, Gu, W.-J, Frost, D.J, Muchmore, S.W, Sham, H.L.
Deposit date:2003-01-06
Release date:2003-02-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Novel and Selective Imidazole-containing Biphenyl Inhibitors of Protein Farnesyltransferase
BIOORG.MED.CHEM.LETT., 13, 2003

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