2V4H
 
 | | NEMO CC2-LZ domain - 1D5 DARPin complex | | Descriptor: | 1D5 DARPIN, NF-KAPPA-B ESSENTIAL MODULATOR | | Authors: | Grubisha, O, Duquerroy, S, Cordier, F, Haouz, A, Delepierre, M, Veron, M, Agou, F. | | Deposit date: | 2008-09-22 | | Release date: | 2009-11-03 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Darpin-Assisted Crystallography of the Cc2-Lz Domain of Nemo Reveals a Coupling between Dimerization and Ubiquitin-Binding.
J.Mol.Biol., 395, 2010
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6ZUJ
 | | Human serine racemase holoenzyme from 20% DMSO soak (XChem crystallographic fragment screen). | | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, DIMETHYL SULFOXIDE, ... | | Authors: | Koulouris, C.R, Bax, B.D, Roe, S.M, Atack, J.R. | | Deposit date: | 2020-07-23 | | Release date: | 2021-03-03 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Tyrosine 121 moves revealing a ligandable pocket that couples catalysis to ATP-binding in serine racemase.
Commun Biol, 5, 2022
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6ZSP
 | | Human serine racemase bound to ATP and malonate. | | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, ... | | Authors: | Koulouris, C.R, Bax, B.D, Roe, S.M, Atack, J.R. | | Deposit date: | 2020-07-16 | | Release date: | 2021-03-03 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Tyrosine 121 moves revealing a ligandable pocket that couples catalysis to ATP-binding in serine racemase.
Commun Biol, 5, 2022
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7NBG
 | | Crystal structure of human serine racemase in complex with DSiP fragment Z52314092, XChem fragment screen. | | Descriptor: | 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, CALCIUM ION, ... | | Authors: | Koulouris, C.R, Roe, S.M. | | Deposit date: | 2021-01-26 | | Release date: | 2021-03-03 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.53 Å) | | Cite: | Tyrosine 121 moves revealing a ligandable pocket that couples catalysis to ATP-binding in serine racemase.
Commun Biol, 5, 2022
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7NBH
 | | Crystal structure of human serine racemase in complex with DSiP fragment Z26781964, XChem fragment screen. | | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Koulouris, C.R, Roe, S.M. | | Deposit date: | 2021-01-26 | | Release date: | 2021-03-03 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.77 Å) | | Cite: | Tyrosine 121 moves revealing a ligandable pocket that couples catalysis to ATP-binding in serine racemase.
Commun Biol, 5, 2022
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7NBD
 | | Crystal structure of human serine racemase in complex with DSiP fragment Z235449082, XChem fragment screen. | | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, GLYCEROL, ... | | Authors: | Koulouris, C.R, Roe, S.M. | | Deposit date: | 2021-01-26 | | Release date: | 2021-03-03 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.865 Å) | | Cite: | Tyrosine 121 moves revealing a ligandable pocket that couples catalysis to ATP-binding in serine racemase.
Commun Biol, 5, 2022
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7NBC
 | | Crystal structure of human serine racemase in complex with DSiP fragment Z2856434779, XChem fragment screen. | | Descriptor: | 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, CALCIUM ION, ... | | Authors: | Koulouris, C.R, Roe, S.M. | | Deposit date: | 2021-01-26 | | Release date: | 2021-03-03 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.71 Å) | | Cite: | Tyrosine 121 moves revealing a ligandable pocket that couples catalysis to ATP-binding in serine racemase.
Commun Biol, 5, 2022
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7NBF
 | | Crystal structure of human serine racemase in complex with DSiP fragment Z126932614, XChem fragment screen. | | Descriptor: | 1,2-ETHANEDIOL, 2-[(methylsulfonyl)methyl]-1H-benzimidazole, CALCIUM ION, ... | | Authors: | Koulouris, C.R, Roe, S.M. | | Deposit date: | 2021-01-26 | | Release date: | 2021-03-03 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Tyrosine 121 moves revealing a ligandable pocket that couples catalysis to ATP-binding in serine racemase.
Commun Biol, 5, 2022
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4BWN
 | | NEMO CC2-LZ DOMAIN | | Descriptor: | NF-KAPPA-B ESSENTIAL MODULATOR | | Authors: | Dubosclard, V, Duquerroy, S, Fontan, E, Agou, F. | | Deposit date: | 2013-07-03 | | Release date: | 2014-07-23 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.27 Å) | | Cite: | High-Resolution of Crystal Structure of the Human Cc2-Lz Domain of Nemo by Protein Engineering
To be Published
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