Author results

1SC9
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HYDROXYNITRILE LYASE FROM HEVEA BRASILIENSIS IN COMPLEX WITH THE NATURAL SUBSTRATE ACETONE CYANOHYDRIN
Descriptor:(S)-acetone-cyanohydrin lyase, SULFATE ION, 2-HYDROXY-2-METHYLPROPANENITRILE
Authors:Gruber, K., Gartler, G., Krammer, B., Schwab, H., Kratky, C.
Deposit date:2004-02-12
Release date:2004-06-29
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Reaction mechanism of hydroxynitrile lyases of the alpha/beta-hydrolase superfamily: the three-dimensional structure of the transient enzyme-substrate complex certifies the crucial role of LYS236
J.Biol.Chem., 279, 2004
1SCI
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K236L MUTANT OF HYDROXYNITRILE LYASE FROM HEVEA BRASILIENSIS
Descriptor:(S)-acetone-cyanohydrin lyase, SULFATE ION
Authors:Gruber, K., Gartler, G., Krammer, B., Schwab, H., Kratky, C.
Deposit date:2004-02-12
Release date:2004-06-29
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Reaction mechanism of hydroxynitrile lyases of the alpha/beta-hydrolase superfamily: the three-dimensional structure of the transient enzyme-substrate complex certifies the crucial role of LYS236
J.Biol.Chem., 279, 2004
1SCK
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K236L MUTANT OF HYDROXYNITRILE LYASE FROM HEVEA BRASILIENSIS IN COMPLEX WITH ACETONE
Descriptor:(S)-acetone-cyanohydrin lyase, SULFATE ION, ACETONE
Authors:Gruber, K., Gartler, G., Krammer, B., Schwab, H., Kratky, C.
Deposit date:2004-02-12
Release date:2004-06-29
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Reaction mechanism of hydroxynitrile lyases of the alpha/beta-hydrolase superfamily: the three-dimensional structure of the transient enzyme-substrate complex certifies the crucial role of LYS236
J.Biol.Chem., 279, 2004
1SCQ
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K236L MUTANT OF HYDROXYNITRILE LYASE FROM HEVEA BRASILIENSIS IN COMPLEX WITH ACETONECYANOHYDRIN
Descriptor:(S)-acetone-cyanohydrin lyase, SULFATE ION, 2-HYDROXY-2-METHYLPROPANENITRILE
Authors:Gruber, K., Gartler, G., Krammer, B., Schwab, H., Kratky, C.
Deposit date:2004-02-12
Release date:2004-06-29
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Reaction mechanism of hydroxynitrile lyases of the alpha/beta-hydrolase superfamily: the three-dimensional structure of the transient enzyme-substrate complex certifies the crucial role of LYS236
J.Biol.Chem., 279, 2004
15C8
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CATALYTIC ANTIBODY 5C8, FREE FAB
Descriptor:IGG 5C8 FAB (LIGHT CHAIN), IGG 5C8 FAB (HEAVY CHAIN)
Authors:Gruber, K., Wilson, I.A.
Deposit date:1998-03-18
Release date:1999-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Ligand-Induced Conformational Changes in a Catalytic Antibody: Comparison of the Bound and Unbound Structure of Fab 5C8
To be Published
1I9C
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GLUTAMATE MUTASE FROM CLOSTRIDIUM COCHLEARIUM: COMPLEX WITH ADENOSYLCOBALAMIN AND SUBSTRATE
Descriptor:GLUTAMATE MUTASE, COBALAMIN, 5'-DEOXYADENOSINE, ...
Authors:Gruber, K., Kratky, C.
Deposit date:2001-03-19
Release date:2002-03-19
Last modified:2012-10-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Radical Shuttling in a Protein: Ribose Pseudorotation Controls Alkyl-Radical Transfer in the Coenzyme B(12) Dependent Enzyme Glutamate Mutase
Angew.Chem.Int.Ed.Engl., 40, 2001
25C8
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CATALYTIC ANTIBODY 5C8, FAB-HAPTEN COMPLEX
Descriptor:IGG 5C8, N-METHYL-N-(PARA-GLUTARAMIDOPHENYL-ETHYL)-PIPERIDINIUM ION
Authors:Gruber, K., Wilson, I.A.
Deposit date:1998-03-18
Release date:1999-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for antibody catalysis of a disfavored ring closure reaction.
Biochemistry, 38, 1999
35C8
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CATALYTIC ANTIBODY 5C8, FAB-INHIBITOR COMPLEX
Descriptor:IGG 5C8, N-(PARA-GLUTARAMIDOPHENYL-ETHYL)-PIPERIDINIUM-N-OXIDE
Authors:Gruber, K., Wilson, I.A.
Deposit date:1998-03-18
Release date:1999-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for antibody catalysis of a disfavored ring closure reaction.
Biochemistry, 38, 1999
1YNA
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ENDO-1,4-BETA-XYLANASE, ROOM TEMPERATURE, PH 4.0
Descriptor:ENDO-1,4-BETA-XYLANASE
Authors:Gruber, K., Kratky, C.
Deposit date:1996-08-22
Release date:1997-02-12
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Thermophilic xylanase from Thermomyces lanuginosus: high-resolution X-ray structure and modeling studies.
Biochemistry, 37, 1998
6FY4
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STRUCTURE OF HUMAN NAD(P) H:QUINONE OXIDOREDUCTASE IN COMPLEX WITH N-(2-BROMOPHENYL)PYRROLIDINE-1-SULFONAMIDE
Descriptor:NAD(P)H dehydrogenase [quinone] 1, FLAVIN-ADENINE DINUCLEOTIDE, N-(2-bromophenyl)pyrrolidine-1-sulfonamide
Authors:Gruber, K., Hromic, A.
Deposit date:2018-03-10
Release date:2019-03-20
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Structure of NOQ1 in complex with N-(2-bromophenyl)pyrrolidine-1-sulfonamide
to be published
1YB6
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HYDROXYNITRILE LYASE FROM HEVEA BRASILIENSIS IN COMPLEX WITH MANDELONITRILE
Descriptor:(S)-acetone-cyanohydrin lyase, SULFATE ION, (S)-MANDELIC ACID NITRILE
Authors:Gruber, K., Gartler, G., Kratky, C.
Deposit date:2004-12-20
Release date:2005-12-20
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Structural determinants of the enantioselectivity of the hydroxynitrile lyase from Hevea brasiliensis
J.Biotechnol., 129, 2007
1YB7
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HYDROXYNITRILE LYASE FROM HEVEA BRASILIENSIS IN COMPLEX WITH 2,3-DIMETHYL-2-HYDROXY-BUTYRONITRILE
Descriptor:(S)-acetone-cyanohydrin lyase, SULFATE ION, (S)-2-HYDROXY-2,3-DIMETHYLBUTANENITRILE
Authors:Gruber, K., Gartler, G., Kratky, C.
Deposit date:2004-12-20
Release date:2005-12-20
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structural determinants of the enantioselectivity of the hydroxynitrile lyase from Hevea brasiliensis
J.Biotechnol., 129, 2007
1QJ4
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HYDROXYNITRILE-LYASE FROM HEVEA BRASILIENSIS AT ATOMIC RESOLUTION
Descriptor:HYDROXYNITRILE LYASE, GLYCEROL, SULFATE ION
Authors:Gugganig, M., Gruber, K., Kratky, C.
Deposit date:1999-06-21
Release date:1999-10-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Atomic Resolution Crystal Structure of Hydroxynitrile Lyase from Hevea Brasiliensis
Biol.Chem., 380, 1999
1CB7
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GLUTAMATE MUTASE FROM CLOSTRIDIUM COCHLEARIUM RECONSTITUTED WITH METHYL-COBALAMIN
Descriptor:PROTEIN (GLUTAMATE MUTASE), CO-METHYLCOBALAMIN, D(-)-TARTARIC ACID
Authors:Gruber, K., Reitzer, R., Kratky, C.
Deposit date:1999-03-03
Release date:2000-02-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Glutamate mutase from Clostridium cochlearium: the structure of a coenzyme B12-dependent enzyme provides new mechanistic insights.
Structure Fold.Des., 7, 1999
2YAS
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HYDROXYNITRILE LYASE FROM HEVEA BRASILIENSIS COMPLEXED WITH RHODANIDE
Descriptor:PROTEIN (HYDROXYNITRILE LYASE), THIOCYANATE ION, SULFATE ION
Authors:Gruber, K., Gugganig, M., Kratky, C.
Deposit date:1999-03-11
Release date:1999-10-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Three-dimensional structures of enzyme-substrate complexes of the hydroxynitrile lyase from Hevea brasiliensis.
Protein Sci., 8, 1999
3ZOC
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CRYSTAL STRUCTURE OF FMN-BINDING PROTEIN (NP_142786.1) FROM PYROCOCCUS HORIKOSHII WITH BOUND P-HYDROXYBENZALDEHYDE
Descriptor:FMN-BINDING PROTEIN, FLAVIN MONONUCLEOTIDE, P-HYDROXYBENZALDEHYDE
Authors:Pavkov-Keller, T., Steinkellner, G., Gruber, C.C., Steiner, K., Winkler, C., Schwamberger, O., Schwab, H., Faber, K., Gruber, K.
Deposit date:2013-02-21
Release date:2014-05-14
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Identification of Promiscuous Ene-Reductase Activity by Mining Structural Databases Using Active Site Constellations.
Nat.Commun., 5, 2014
3ZOD
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CRYSTAL STRUCTURE OF FMN-BINDING PROTEIN (NP_142786.1) FROM PYROCOCCUS HORIKOSHII WITH BOUND BENZENE-1,4-DIOL
Descriptor:FMN-BINDING PROTEIN, FLAVIN MONONUCLEOTIDE, benzene-1,4-diol
Authors:Pavkov-Keller, T., Steinkellner, G., Gruber, C.C., Steiner, K., Winkler, C., Schwamberger, O., Schwab, H., Faber, K., Gruber, K.
Deposit date:2013-02-21
Release date:2014-05-14
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Identification of Promiscuous Ene-Reductase Activity by Mining Structural Databases Using Active Site Constellations.
Nat.Commun., 5, 2014
3ZOE
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CRYSTAL STRUCTURE OF FMN-BINDING PROTEIN (YP_005476) FROM THERMUS THERMOPHILUS WITH BOUND P-HYDROXYBENZALDEHYDE
Descriptor:FLAVOREDOXIN, P-HYDROXYBENZALDEHYDE, FLAVIN MONONUCLEOTIDE
Authors:Pavkov-Keller, T., Steinkellner, G., Gruber, C.C., Steiner, K., Winkler, C., Schwamberger, O., Schwab, H., Faber, K., Gruber, K.
Deposit date:2013-02-21
Release date:2014-05-14
Last modified:2014-07-02
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Identification of Promiscuous Ene-Reductase Activity by Mining Structural Databases Using Active Site Constellations.
Nat.Commun., 5, 2014
3ZOF
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CRYSTAL STRUCTURE OF FMN-BINDING PROTEIN (YP_005476) FROM THERMUS THERMOPHILUS WITH BOUND BENZENE-1,4-DIOL
Descriptor:FLAVOREDOXIN, benzene-1,4-diol, FLAVIN MONONUCLEOTIDE
Authors:Pavkov-Keller, T., Steinkellner, G., Gruber, C.C., Steiner, K., Winkler, C., Schwamberger, O., Schwab, H., Faber, K., Gruber, K.
Deposit date:2013-02-21
Release date:2014-05-14
Last modified:2014-07-02
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Identification of Promiscuous Ene-Reductase Activity by Mining Structural Databases Using Active Site Constellations.
Nat.Commun., 5, 2014
3ZOG
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CRYSTAL STRUCTURE OF FMN-BINDING PROTEIN (NP_142786.1) FROM PYROCOCCUS HORIKOSHII WITH BOUND 1-CYCLOHEX-2-ENONE
Descriptor:FMN-BINDING PROTEIN, FLAVIN MONONUCLEOTIDE, cyclohex-2-en-1-one
Authors:Pavkov-Keller, T., Steinkellner, G., Gruber, C.C., Steiner, K., Winkler, C., Schwamberger, O., Schwab, H., Faber, K., Gruber, K.
Deposit date:2013-02-21
Release date:2014-05-14
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Identification of Promiscuous Ene-Reductase Activity by Mining Structural Databases Using Active Site Constellations.
Nat.Commun., 5, 2014
3ZOH
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CRYSTAL STRUCTURE OF FMN-BINDING PROTEIN (YP_005476) FROM THERMUS THERMOPHILUS WITH BOUND 1-CYCLOHEX-2-ENONE
Descriptor:FLAVOREDOXIN, cyclohex-2-en-1-one, FLAVIN MONONUCLEOTIDE
Authors:Pavkov-Keller, T., Steinkellner, G., Gruber, C.C., Steiner, K., Winkler, C., Schwamberger, O., Schwab, H., Faber, K., Gruber, K.
Deposit date:2013-02-21
Release date:2014-05-14
Last modified:2014-07-02
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Identification of Promiscuous Ene-Reductase Activity by Mining Structural Databases Using Active Site Constellations.
Nat.Commun., 5, 2014
4CE5
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FIRST CRYSTAL STRUCTURE OF AN (R)-SELECTIVE OMEGA-TRANSAMINASE FROM ASPERGILLUS TERREUS
Descriptor:AT-OMEGATA, PYRIDOXAL-5'-PHOSPHATE, N-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-D-GLUTAMIC ACID, ...
Authors:Lyskowski, A., Gruber, C., Steinkellner, G., Schurmann, M., Schwab, H., Gruber, K., Steiner, K.
Deposit date:2013-11-08
Release date:2014-02-12
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Crystal Structure of an (R)-Selective Omega-Transaminase from Aspergillus Terreus
Plos One, 9, 2014
5M58
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CRYSTAL STRUCTURE OF COUO, A C-METHYLTRANSFERASE FROM STREPTOMYCES RISHIRIENSIS
Descriptor:C-methyltransferase CouO, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Pavkov-Keller, T., Gruber, K.
Deposit date:2016-10-20
Release date:2017-02-15
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal Structure and Catalytic Mechanism of CouO, a Versatile C-Methyltransferase from Streptomyces rishiriensis.
PLoS ONE, 12, 2017
5E46
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HYDROXYNITRILE LYASE FROM THE FERN DAVALLIA TYERMANII
Descriptor:Hydroxynitrile lyase
Authors:Pavkov-Keller, T., Diepold, M., Gruber, K.
Deposit date:2015-10-05
Release date:2016-10-05
Last modified:2016-12-21
Method:X-RAY DIFFRACTION (1.854 Å)
Cite:Unique and novel enzymes catalyze cyanide release from fern
to be published
5E4B
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HYDROXYNITRILE LYASE FROM THE FERN DAVALLIA TYERMANII IN COMPLEX WITH (R)-MANDELONITRILE / BENZALDEHYDE
Descriptor:Hydroxynitrile lyase, benzaldehyde, (2R)-hydroxy(phenyl)ethanenitrile
Authors:Pavkov-Keller, T., Diepold, M., Gruber, K.
Deposit date:2015-10-05
Release date:2016-10-05
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Unique and novel enzymes catalyze cyanide release from fern
to be published