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3MA2
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BU of 3ma2 by Molmil
Complex membrane type-1 matrix metalloproteinase (MT1-MMP) with tissue inhibitor of metalloproteinase-1 (TIMP-1)
Descriptor: CALCIUM ION, Matrix metalloproteinase-14, Metalloproteinase inhibitor 1, ...
Authors:Grossman, M, Tworowski, D, Dym, O, Lee, M.-H, Levy, Y, Sagi, I.
Deposit date:2010-03-23
Release date:2010-06-30
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The Intrinsic Protein Flexibility of Endogenous Protease Inhibitor TIMP-1 Controls Its Binding Interface and Affects Its Function.
Biochemistry, 49, 2010
4IJO
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BU of 4ijo by Molmil
Unraveling hidden allosteric regulatory sites in structurally homologues metalloproteases
Descriptor: CALCIUM ION, Macrophage metalloelastase, ZINC ION
Authors:Udi, Y, Fragai, M, Grossman, M, Mitternacht, S, Arad-Yellin, R, Calderone, V, Melikian, M, Toccafondi, M, Berezovsky, I.N, Luchinat, C, Sagi, I.
Deposit date:2012-12-22
Release date:2013-05-01
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Unraveling hidden regulatory sites in structurally homologous metalloproteases
J.Mol.Biol., 425, 2013
4QXU
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BU of 4qxu by Molmil
Novel Inhibition Mechanism of Membrane Metalloprotease by an Exosite-Swiveling Conformational antibody
Descriptor: Matrix metalloproteinase-14, SULFATE ION, anti_MT1-MMP Heavy chain, ...
Authors:Udi, Y, Grossman, M, Solomonov, I, Dym, O, Rozenberg, H, Moreno, v, Cuiniasse, P, Dive, V, Arroyo, A.G, Sagi, I, Israel Structural Proteomics Center (ISPC)
Deposit date:2014-07-22
Release date:2014-12-17
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Inhibition mechanism of membrane metalloprotease by an exosite-swiveling conformational antibody.
Structure, 23, 2015
4OUU
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BU of 4ouu by Molmil
anti-MT1-MMP monoclonal antibody
Descriptor: anti_MT1-MMP Heavy chain, anti_MT1-MMP light chain
Authors:Udi, Y, Grossman, M, Solomonov, I, Dym, O, Rozenberg, H, Koziol, A, Cuniasse, P, Dive, V, Arroyo, A.G, Irit, S, Israel Structural Proteomics Center (ISPC)
Deposit date:2014-02-19
Release date:2014-12-17
Last modified:2015-01-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Inhibition mechanism of membrane metalloprotease by an exosite-swiveling conformational antibody.
Structure, 23, 2015
5H0U
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BU of 5h0u by Molmil
Crystal structure of the catalytic domain of membrane type 1 matrix metalloproteinase
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ...
Authors:Ogata, H, Decaneto, E, Lubitz, W.
Deposit date:2016-10-07
Release date:2017-10-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.239 Å)
Cite:Solvent water interactions within the active site of the membrane type I matrix metalloproteinase.
Phys Chem Chem Phys, 19, 2017
4P3C
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BU of 4p3c by Molmil
MT1-MMP:Fab complex (Form I)
Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, ...
Authors:Rozenberg, H, Udi, Y, Sagi, I.
Deposit date:2014-03-06
Release date:2014-12-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.943 Å)
Cite:Inhibition mechanism of membrane metalloprotease by an exosite-swiveling conformational antibody.
Structure, 23, 2015
4P3D
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BU of 4p3d by Molmil
MT1-MMP:Fab complex (Form II)
Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ...
Authors:Rozenberg, H, Udi, Y, Sagi, I.
Deposit date:2014-03-07
Release date:2014-12-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.949 Å)
Cite:Inhibition mechanism of membrane metalloprotease by an exosite-swiveling conformational antibody.
Structure, 23, 2015

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