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1RF8
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BU of 1rf8 by Molmil
Solution structure of the yeast translation initiation factor eIF4E in complex with m7GDP and eIF4GI residues 393 to 490
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, Eukaryotic initiation factor 4F subunit p150, Eukaryotic translation initiation factor 4E, ...
Authors:Gross, J.D, Moerke, N.J, von der Haar, T, Lugovskoy, A.A, Sachs, A.B, McCarthy, J.E.G, Wagner, G.
Deposit date:2003-11-07
Release date:2003-12-23
Last modified:2024-03-06
Method:SOLUTION NMR
Cite:Ribosome loading onto the mRNA cap is driven by conformational coupling between eIF4G and eIF4E.
Cell(Cambridge,Mass.), 115, 2003
3OEO
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BU of 3oeo by Molmil
The crystal structure E. coli Spy
Descriptor: CADMIUM ION, Spheroplast protein Y
Authors:Kwon, E, Kim, D.Y, Gross, C.A, Gross, J.D, Kim, K.K.
Deposit date:2010-08-13
Release date:2010-09-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The crystal structure Escherichia coli Spy.
Protein Sci., 19, 2010
5KQ4
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BU of 5kq4 by Molmil
Crystal structure of S. pombe Dcp1/Dcp2 in complex with H. sapiens PNRC2 and synthetic cap analog
Descriptor: Proline-rich nuclear receptor coactivator 2, [[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanylidene-3~{H}-purin-7-ium-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-sulfanyl-phosphoryl] [[[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanylidene-3~{H}-purin-7-ium-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-sulfanyl-phosphoryl]oxy-oxidanyl-phosphoryl] hydrogen phosphate, mRNA decapping complex subunit 2, ...
Authors:Mugridge, J.S, Ziemniak, M, Jemielity, J, Gross, J.D.
Deposit date:2016-07-05
Release date:2016-10-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Structural basis of mRNA-cap recognition by Dcp1-Dcp2.
Nat.Struct.Mol.Biol., 23, 2016
5KQ1
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BU of 5kq1 by Molmil
Crystal structure of S. pombe Dcp1/Dcp2 in complex with H. sapiens PNRC2
Descriptor: Proline-rich nuclear receptor coactivator 2, mRNA decapping complex subunit 2, mRNA-decapping enzyme subunit 1
Authors:Mugridge, J.S, Ziemniak, M, Jemielity, J, Gross, J.D.
Deposit date:2016-07-05
Release date:2016-10-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.002 Å)
Cite:Structural basis of mRNA-cap recognition by Dcp1-Dcp2.
Nat.Struct.Mol.Biol., 23, 2016
3V67
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BU of 3v67 by Molmil
Periplasmic domain of Vibrio parahaemolyticus CpxA
Descriptor: Sensor protein CpxA
Authors:Kwon, E, Kim, D.Y, Ngo, T.D, Gross, J.D, Kim, K.K.
Deposit date:2011-12-19
Release date:2012-09-26
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The crystal structure of the periplasmic domain of Vibrio parahaemolyticus CpxA
Protein Sci., 21, 2012
2KEM
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BU of 2kem by Molmil
Extended structure of citidine deaminase domain of APOBEC3G
Descriptor: DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION
Authors:Harjes, E, Gross, P.J, Chen, K, Lu, Y, Shindo, K, Nowarski, R, Gross, J.D, Kotler, M, Harris, R.S, Matsuo, H.
Deposit date:2009-01-30
Release date:2009-06-02
Last modified:2021-11-10
Method:SOLUTION NMR
Cite:An extended structure of the APOBEC3G catalytic domain suggests a unique holoenzyme model
J.Mol.Biol., 389, 2009
4KG4
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BU of 4kg4 by Molmil
Crystal structure of Saccharomyces cerevisiae Dcp2 Nudix domain (E198Q mutation)
Descriptor: mRNA-decapping enzyme subunit 2
Authors:Aglietti, R.A, Floor, S.N, Gross, J.D.
Deposit date:2013-04-28
Release date:2013-08-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Active site conformational dynamics are coupled to catalysis in the mRNA decapping enzyme dcp2.
Structure, 21, 2013
4K6E
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BU of 4k6e by Molmil
Crystal structure of Saccharomyces cerevisiae Dcp2 Nudix domain in complex with Mg
Descriptor: MAGNESIUM ION, mRNA-decapping enzyme subunit 2
Authors:Aglietti, R.A, Floor, S.N, Gross, J.D.
Deposit date:2013-04-15
Release date:2013-08-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Active site conformational dynamics are coupled to catalysis in the mRNA decapping enzyme dcp2.
Structure, 21, 2013
4KG3
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BU of 4kg3 by Molmil
Crystal structure of Saccharomyces cerevisiae Dcp2 Nudix domain in complex with Mg (E153Q mutation)
Descriptor: MAGNESIUM ION, mRNA-decapping enzyme subunit 2
Authors:Aglietti, R.A, Floor, S.N, Gross, J.D.
Deposit date:2013-04-28
Release date:2013-08-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Active site conformational dynamics are coupled to catalysis in the mRNA decapping enzyme dcp2.
Structure, 21, 2013
1ZGW
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BU of 1zgw by Molmil
NMR structure of E. Coli Ada protein in complex with DNA
Descriptor: 5'-D(*GP*CP*AP*AP*AP*TP*TP*AP*AP*AP*GP*CP*GP*CP*AP*AP*GP*A)-3', 5'-D(*TP*CP*TP*TP*GP*CP*GP*CP*TP*TP*TP*AP*AP*TP*TP*TP*GP*C)-3', Ada polyprotein, ...
Authors:He, C, Hus, J.C, Sun, L.J, Zhou, P, Norman, D.P, Doetsch, V, Wei, H, Gross, J.D, Lane, W.S, Wagner, G, Verdine, G.L.
Deposit date:2005-04-22
Release date:2005-10-18
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:A Methylation-Dependent Electrostatic Switch Controls DNA Repair and Transcriptional Activation by E. coli Ada.
Mol.Cell, 20, 2005
1TVC
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BU of 1tvc by Molmil
FAD and NADH binding domain of methane monooxygenase reductase from Methylococcus capsulatus (Bath)
Descriptor: DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, METHANE MONOOXYGENASE COMPONENT C
Authors:Chatwood, L.L, Mueller, J, Gross, J.D, Wagner, G, Lippard, S.J.
Deposit date:2004-06-29
Release date:2004-10-12
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:NMR Structure of the Flavin Domain from Soluble Methane Monooxygenase Reductase from Methylococcus capsulatus (Bath)
Biochemistry, 43, 2004
1U8B
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BU of 1u8b by Molmil
Crystal structure of the methylated N-ADA/DNA complex
Descriptor: 5'-D(*AP*AP*TP*CP*TP*TP*GP*CP*GP*CP*TP*TP*T)-3', 5'-D(*TP*AP*AP*AP*TP*T)-3', 5'-D(P*AP*AP*AP*GP*CP*GP*CP*AP*AP*GP*AP*T)-3', ...
Authors:He, C, Hus, J.-C, Sun, L.J, Zhou, P, Norman, D.P.G, Dotsch, V, Gross, J.D, Lane, W.S, Wagner, G, Verdine, G.L.
Deposit date:2004-08-05
Release date:2005-10-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A methylation-dependent electrostatic switch controls DNA repair and transcriptional activation by E. coli ada.
Mol.Cell, 20, 2005
6AM0
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BU of 6am0 by Molmil
Crystal structure of K. lactis Edc1-Dcp1-Dcp2-Edc3 decapping complex with synthetic cap substrate analog
Descriptor: KLLA0A01474p, KLLA0A11308p, KLLA0E01827p, ...
Authors:Mugridge, J.S, Gross, J.D.
Deposit date:2017-08-08
Release date:2018-03-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Structure of the activated Edc1-Dcp1-Dcp2-Edc3 mRNA decapping complex with substrate analog poised for catalysis.
Nat Commun, 9, 2018
6P59
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BU of 6p59 by Molmil
Crystal structure of SIVrcm Vif-CBFbeta-ELOB-ELOC complex
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Core-binding factor subunit beta, Elongin-B, ...
Authors:Binning, J.M, Chesarino, N.M, Emerman, M, Gross, J.D.
Deposit date:2019-05-29
Release date:2019-12-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.942214 Å)
Cite:Structural Basis for a Species-Specific Determinant of an SIV Vif Protein toward Hominid APOBEC3G Antagonism.
Cell Host Microbe, 26, 2019
8CX1
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BU of 8cx1 by Molmil
Cryo-EM structure of human APOBEC3G/HIV-1 Vif/CBFbeta/ELOB/ELOC dimeric complex in State 1
Descriptor: Core-binding factor subunit beta, DNA dC->dU-editing enzyme APOBEC-3G, Elongin-B, ...
Authors:Li, Y, Langley, C, Azumaya, C.M, Echeverria, I, Chesarino, N.M, Emerman, M, Cheng, Y, Gross, J.D.
Deposit date:2022-05-19
Release date:2023-02-15
Last modified:2023-04-05
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:The structural basis for HIV-1 Vif antagonism of human APOBEC3G.
Nature, 615, 2023
8CX0
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BU of 8cx0 by Molmil
Cryo-EM structure of human APOBEC3G/HIV-1 Vif/CBFbeta/ELOB/ELOC monomeric complex
Descriptor: Core-binding factor subunit beta, DNA dC->dU-editing enzyme APOBEC-3G, Elongin-B, ...
Authors:Li, Y, Langley, C, Azumaya, C.M, Echeverria, I, Chesarino, N.M, Emerman, M, Cheng, Y, Gross, J.D.
Deposit date:2022-05-19
Release date:2023-02-15
Last modified:2023-04-05
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:The structural basis for HIV-1 Vif antagonism of human APOBEC3G.
Nature, 615, 2023
8CX2
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BU of 8cx2 by Molmil
Cryo-EM structure of human APOBEC3G/HIV-1 Vif/CBFbeta/ELOB/ELOC dimeric complex in State 2
Descriptor: Core-binding factor subunit beta, DNA dC->dU-editing enzyme APOBEC-3G, Elongin-B, ...
Authors:Li, Y, Langley, C, Azumaya, C.M, Echeverria, I, Chesarino, N.M, Emerman, M, Cheng, Y, Gross, J.D.
Deposit date:2022-05-19
Release date:2023-02-15
Last modified:2023-04-05
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:The structural basis for HIV-1 Vif antagonism of human APOBEC3G.
Nature, 615, 2023
7SEZ
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BU of 7sez by Molmil
Crystal structure of Vaccinia Virus decapping enzyme D9 in complex with m7GDP
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, DNA repair NTP-phosphohydrolase, SODIUM ION
Authors:Peters, J.K, Tibble, R.W, Warminski, M, Jemielity, J, Gross, J.D.
Deposit date:2021-10-02
Release date:2022-03-30
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.70001245 Å)
Cite:Structure of the poxvirus decapping enzyme D9 reveals its mechanism of cap recognition and catalysis.
Structure, 30, 2022
7SF0
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BU of 7sf0 by Molmil
Crystal structure of Vaccinia Virus decapping enzyme D9 in complex with trinucleotide substrate
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, DNA repair NTP-phosphohydrolase, MAGNESIUM ION, ...
Authors:Peters, J.K, Tibble, R.W, Warminski, M, Jemielity, J, Gross, J.D.
Deposit date:2021-10-02
Release date:2022-03-30
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.95000446 Å)
Cite:Structure of the poxvirus decapping enzyme D9 reveals its mechanism of cap recognition and catalysis.
Structure, 30, 2022
7T7H
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BU of 7t7h by Molmil
Crystal structure of Vaccinia Virus decapping enzyme D9 in complex with inhibitor CP100356
Descriptor: 4-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-6,7-dimethoxyquinazolin-2-amine, DNA repair NTP-phosphohydrolase, SODIUM ION
Authors:Peters, J.K, Gross, J.D.
Deposit date:2021-12-15
Release date:2022-06-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.78000259 Å)
Cite:Fluorescence-Based Activity Screening Assay Reveals Small Molecule Inhibitors of Vaccinia Virus mRNA Decapping Enzyme D9.
Acs Chem.Biol., 17, 2022
2JVB
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BU of 2jvb by Molmil
Solution Structure of Catalytic Domain of yDcp2
Descriptor: mRNA-decapping enzyme subunit 2
Authors:Deshmukh, M, Gross, J.
Deposit date:2007-09-16
Release date:2008-03-04
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:mRNA Decapping Is Promoted by an RNA-Binding Channel in Dcp2.
Mol.Cell, 29, 2008
6C3R
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BU of 6c3r by Molmil
Cricket paralysis virus RNAi suppressor protein CrPV-1A
Descriptor: Cricket paralysis virus 1A protein
Authors:Nayak, A, Kim, D.Y, Andino, R, Gross, J.
Deposit date:2018-01-10
Release date:2018-10-17
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A Viral Protein Restricts Drosophila RNAi Immunity by Regulating Argonaute Activity and Stability.
Cell Host Microbe, 24, 2018

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PDB entries from 2024-03-27

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