Author results

4V98
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THE 8S SNRNP ASSEMBLY INTERMEDIATE
Descriptor:Small nuclear ribonucleoprotein Sm D1, Small nuclear ribonucleoprotein Sm D2, Small nuclear ribonucleoprotein E, ...
Authors:Grimm, C., Pelz, J.P., Schindelin, H., Diederichs, K., Kuper, J., Kisker, C.
Deposit date:2012-05-15
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural Basis of Assembly Chaperone- Mediated snRNP Formation.
Mol.Cell, 49, 2013
1MUM
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STRUCTURE OF THE 2-METHYLISOCITRATE LYASE (PRPB) FROM ESCHERICHIA COLI
Descriptor:2-methylisocitrate lyase, MAGNESIUM ION
Authors:Grimm, C., Reuter, K.
Deposit date:2002-09-24
Release date:2003-04-29
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of 2-methylisocitrate lyase (PrpB) from Escherichia coli and modelling of its ligand bound active centre.
J.Mol.Biol., 328, 2003
4F7U
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THE 6S SNRNP ASSEMBLY INTERMEDIATE
Descriptor:Small nuclear ribonucleoprotein Sm D1, Small nuclear ribonucleoprotein Sm D2, Small nuclear ribonucleoprotein E, ...
Authors:Grimm, C., Pelz, J.P.
Deposit date:2012-05-16
Release date:2013-01-30
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (1.898 Å)
Cite:Structural Basis of Assembly Chaperone- Mediated snRNP Formation.
Mol.Cell, 49, 2013
1FJH
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THE CRYSTAL STRUCTURE OF 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE FROM COMAMONAS TESTOSTERONI, A MEMBER OF THE SHORT CHAIN DEHYDROGENASE/REDUCTASE FAMILY
Descriptor:3ALPHA-HYDROXYSTEROID DEHYDROGENASE/CARBONYL REDUCTASE
Authors:Grimm, C., Ficner, R., Maser, E., Klebe, G., Reuter, K.
Deposit date:2000-08-08
Release date:2001-01-17
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:The crystal structure of 3alpha -hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni shows a novel oligomerization pattern within the short chain dehydrogenase/reductase family.
J.Biol.Chem., 275, 2000
1FK8
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THE CRYSTAL STRUCTURE OF THE BINARY COMPLEX WITH NAD OF 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE FROM COMAMONAS TESTOSTERONI, A MEMBER OF THE SHORT CHAIN DEHYDROGENASE/REDUCTASE FAMILY
Descriptor:3ALPHA-HYDROXYSTEROID DEHYDROGENASE/CARBONYL REDUCTASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Grimm, C., Ficner, R., Maser, E., Klebe, G., Reuter, K.
Deposit date:2000-08-09
Release date:2001-01-17
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The crystal structure of 3alpha -hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni shows a novel oligomerization pattern within the short chain dehydrogenase/reductase family.
J.Biol.Chem., 275, 2000
1YY3
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STRUCTURE OF S-ADENOSYLMETHIONINE:TRNA RIBOSYLTRANSFERASE-ISOMERASE (QUEA)
Descriptor:S-adenosylmethionine:tRNA ribosyltransferase-isomerase
Authors:Grimm, C., Ficner, R., Reuter, K.
Deposit date:2005-02-23
Release date:2006-03-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:Crystal structure of Bacillus subtilis S-adenosylmethionine:tRNA ribosyltransferase-isomerase
Biochem.Biophys.Res.Commun., 351, 2006
2R57
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CRYSTAL STRUCTURE OF THE TWO MBT REPEATS FROM SEX-COMB ON MIDLEG (SCM)
Descriptor:Polycomb protein Scm
Authors:Grimm, C., Steuerwald, U., Mueller, C.W.
Deposit date:2007-09-03
Release date:2007-10-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and functional analyses of methyl-lysine binding by the malignant brain tumour repeat protein Sex comb on midleg.
Embo Rep., 8, 2007
2R58
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CRYSTAL STRUCTURE OF THE TWO MBT REPEATS FROM SEX-COMB ON MIDLEG (SCM) IN COMPLEX WITH DI-METHYL LYSINE
Descriptor:Polycomb protein Scm, N-DIMETHYL-LYSINE
Authors:Grimm, C., Steuerwald, U., Mueller, C.W.
Deposit date:2007-09-03
Release date:2007-10-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and functional analyses of methyl-lysine binding by the malignant brain tumour repeat protein Sex comb on midleg.
Embo Rep., 8, 2007
2R5A
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CRYSTAL STRUCTURE OF THE TWO MBT REPEATS FROM SEX-COMB ON MIDLEG (SCM) IN COMPLEX WITH METHYL LYSINE
Descriptor:Polycomb protein Scm, N-METHYL-LYSINE
Authors:Grimm, C., Steuerwald, U., Mueller, C.W.
Deposit date:2007-09-03
Release date:2007-10-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and functional analyses of methyl-lysine binding by the malignant brain tumour repeat protein Sex comb on midleg.
Embo Rep., 8, 2007
2R5M
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CRYSTAL STRUCTURE OF THE TWO MBT REPEATS FROM SEX-COMB ON MIDLEG (SCM) IN COMPLEX WITH PEPTIDE R-(ME)K-S
Descriptor:Polycomb protein Scm, peptide R(me)KS
Authors:Grimm, C., Steuerwald, U., Mueller, C.W.
Deposit date:2007-09-04
Release date:2007-10-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural and functional analyses of methyl-lysine binding by the malignant brain tumour repeat protein Sex comb on midleg.
Embo Rep., 8, 2007
3H6Z
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CRYSTAL STRUCTURE OF THE FOUR MBT REPEATS OF DROSOPHILA MELANOGASTER SFMBT IN COMPLEX WITH PEPTIDE RHR (ME)K VLR
Descriptor:Polycomb protein Sfmbt, 'HR(MLZ)VLR, SUCROSE
Authors:Grimm, C., Mueller, C.W.
Deposit date:2009-04-24
Release date:2009-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular recognition of histone lysine methylation by the Polycomb group repressor dSfmbt
Embo J., 28, 2009
3PTH
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THE PABC1 MLLE DOMAIN BOUND TO THE VARIANT PAM2 MOTIF OF LARP4B
Descriptor:Polyadenylate-binding protein 1, La-related protein 4B
Authors:Grimm, C., Pelz, J.P.
Deposit date:2010-12-03
Release date:2011-12-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:LARP4B binds to the PABC1 MLLE domain via a variant PAM2 motif
To be Published
4FL9
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CRYSTAL STRUCTURE OF BOVINE HSC70(AA1-554)E213A/D214A AT 1.9A RESOLUTION
Descriptor:Heat shock cognate 71 kDa protein, trimethylamine oxide, 2,3-DIHYDROXY-1,4-DITHIOBUTANE
Authors:Grimm, C.
Deposit date:2012-06-14
Release date:2013-10-02
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Crystal Structure of bovine hsc70(aa1-554)E213A/D214A at 1.9A Resolution
TO BE PUBLISHED
4Q1P
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GALECTIN-1 IN COMPLEX WITH LIGAND NB169
Descriptor:Galectin-1, propyl 2-(acetylamino)-4-O-{3-O-[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]-beta-D-galactopyranosyl}-2-deoxy-beta-D-glucopyranoside, BETA-MERCAPTOETHANOL, ...
Authors:Grimm, C., Bertleff-Zieschang, N.
Deposit date:2014-04-04
Release date:2015-10-07
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Galectin-1 in Complex with Ligand NB169
To be Published
4Q1R
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GALECTIN-1 IN COMPLEX WITH LIGAND AN027
Descriptor:Galectin-1, propyl 2-(acetylamino)-2-deoxy-4-O-[3-O-({1-[2-(3-hydroxyphenyl)-2-oxoethyl]-1H-1,2,3-triazol-4-yl}methyl)-beta-D-galactopyranosyl]-beta-D-glucopyranoside, SULFATE ION
Authors:Grimm, C., Bertleff-Zieschang, N.
Deposit date:2014-04-04
Release date:2015-10-07
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Galectin-1 in Complex with Ligand AN027
To be Published
4Q26
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CRYSTAL STRUCTURE OF GALECTIN-1 IN COMPLEX WITH N-ACETYLLACTOSAMINE
Descriptor:Galectin-1, 2-(ACETYLAMINO)-2-DEOXY-4-O-BETA-D-GALACTOPYRANOSYL-ALPHA-D-GLUCOPYRANOSE, GLYCEROL
Authors:Grimm, C., Bertleff-Zieschang, N.
Deposit date:2014-04-07
Release date:2015-10-07
Method:X-RAY DIFFRACTION (1.399 Å)
Cite:Crystal Structure of Galectin-1 in Complex with N-Acetyllactosamine
To be Published
4Q27
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GALECTIN-1 IN COMPLEX WITH A CLICK-ACTIVATED N-ACETYLLACTOSAMINE
Descriptor:Galectin-1, prop-2-en-1-yl 2-(acetylamino)-2-deoxy-4-O-[3-O-(prop-2-yn-1-yl)-beta-D-galactopyranosyl]-beta-D-glucopyranoside, SULFATE ION
Authors:Grimm, C., Bertleff-Zieschang, N.
Deposit date:2014-04-07
Release date:2015-10-07
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Galectin-1 in Complex with a Click-Activated N-Acetyllactosamine
To be Published
4Q2F
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GALECTIN-1 IN COMPLEX WITH LIGAND AN020
Descriptor:Galectin-1, prop-2-en-1-yl 2-(acetylamino)-4-O-(3-O-{[1-(5-amino-1H-1,2,4-triazol-3-yl)-1H-1,2,3-triazol-4-yl]methyl}-beta-D-galactopyranosyl)-2-deoxy-beta-D-glucopyranoside, SULFATE ION
Authors:Grimm, C., Bertleff-Zieschang, N.
Deposit date:2014-04-08
Release date:2015-10-07
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Galectin-1 in Complex with Ligand AN020
To be Published
5MB2
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STRUCTURE OF SUCROSE PHOSPHORYLASE FROM BIFIDOBACTERIUM ADOLESCENTIS BOUND TO NIGEROSE
Descriptor:Sucrose phosphorylase, GLYCEROL
Authors:Grimm, C., Kraus, M.
Deposit date:2016-11-07
Release date:2017-12-20
Method:X-RAY DIFFRACTION (1.752 Å)
Cite:Structure of sucrose phosphorylase from Bifidobacterium adolescentis bound to nigerose
To Be Published
5MWT
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GALECTIN-1 IN COMPLEX WITH LIGAND JB97
Descriptor:Galectin-1, BETA-MERCAPTOETHANOL, ~{N}-[(2~{R},3~{R},4~{R},5~{S},6~{R})-5-[(2~{S},3~{R},4~{S},5~{S},6~{R})-4-[[1-[[3-[(~{Z})-3-[bis(azanyl)methylideneamino]prop-1-enyl]phenyl]methyl]-1,2,3-triazol-4-yl]methoxy]-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-2-yl]oxy-6-(hydroxymethyl)-4-oxidanyl-2-prop-2-enoxy-oxan-3-yl]ethanamide, ...
Authors:Grimm, C., Bechold, J.
Deposit date:2017-01-19
Release date:2018-02-14
Method:X-RAY DIFFRACTION (1.711 Å)
Cite:Structural insights into the redesign of a sucrose phosphorylase by induced loop repositioning
To Be Published
5MWX
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GALECTIN-1 IN COMPLEX WITH LIGAND JB60
Descriptor:Galectin-1, BETA-MERCAPTOETHANOL, ~{N}-[(2~{R},3~{R},4~{R},5~{S},6~{R})-5-[(2~{S},3~{R},4~{S},5~{S},6~{R})-4-[[1-[[3-(3-azanylprop-1-ynyl)phenyl]methyl]-1,2,3-triazol-4-yl]methoxy]-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-2-yl]oxy-6-(hydroxymethyl)-4-oxidanyl-2-propoxy-oxan-3-yl]ethanamide, ...
Authors:Grimm, C., Bechold, J.
Deposit date:2017-01-20
Release date:2018-02-28
Method:X-RAY DIFFRACTION (1.29 Å)
Cite:Galectin-1 in Complex with Ligand JB60
To Be Published
6FME
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STRUCTURE OF SUCROSE PHOSPHORYLASE FROM BIFIDOBACTERIUM ADOLESCENTIS BOUND TO GLYCOSYLATED RESVERATROL
Descriptor:Sucrose phosphorylase, GLYCEROL
Authors:Grimm, C., Kraus, M.
Deposit date:2018-01-31
Release date:2019-03-13
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Structure of sucrose phosphorylase from Bifidobacterium adolescentis bound to glycosylated resveratrol
To Be Published
4WKG
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THE CRYSTAL STRUCTURE OF APO ARNA FEATURES AN UNEXPECTED CENTRAL BINDING POCKET AND PROVIDES AN EXPLANATION FOR ENZYMATIC COOP-ERATIVITY
Descriptor:Bifunctional polymyxin resistance protein ArnA, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ACETATE ION
Authors:Grimm, C.
Deposit date:2014-10-02
Release date:2014-12-17
Last modified:2016-07-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The structure of apo ArnA features an unexpected central binding pocket and provides an explanation for enzymatic cooperativity.
Acta Crystallogr.,Sect.D, 71, 2015
5C8B
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STRUCTURAL INSIGHTS INTO THE REDESIGN OF A SUCROSE PHOSPHORYLASE BY INDUCED LOOP REPOSITIONING
Descriptor:Sucrose phosphorylase, BETA-D-GLUCOSE
Authors:Grimm, C., Kraus, M.
Deposit date:2015-06-25
Release date:2016-01-20
Last modified:2016-07-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Redesign of the Active Site of Sucrose Phosphorylase through a Clash-Induced Cascade of Loop Shifts.
Chembiochem, 17, 2016
5M9X
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STRUCTURE OF SUCROSE PHOSPHORYLASE FROM BIFIDOBACTERIUM ADOLESCENTIS BOUND TO GLYCOSYLATED RESVERATROL
Descriptor:Sucrose phosphorylase, (2~{R},3~{S},4~{S},5~{R},6~{R})-2-(hydroxymethyl)-6-[3-[(~{E})-2-(4-hydroxyphenyl)ethenyl]-5-oxidanyl-phenoxy]oxane-3,4,5-triol
Authors:Grimm, C., Kraus, M.
Deposit date:2016-11-02
Release date:2017-12-20
Method:X-RAY DIFFRACTION (2.349 Å)
Cite:Switching enzyme specificity from phosphate to resveratrol glucosylation.
Chem. Commun. (Camb.), 53, 2017
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