Author results

5NWX
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INSIGHT INTO THE MOLECULAR RECOGNITION MECHANISM OF THE COACTIVATOR NCOA1 BY STAT6
Descriptor:Nuclear receptor coactivator 1, Signal transducer and activator of transcription 6
Authors:Russo, L., Giller, K., Pfitzner, E., Griesinger, C., Becker, S.
Deposit date:2017-05-08
Release date:2017-12-13
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Insight into the molecular recognition mechanism of the coactivator NCoA1 by STAT6.
Sci Rep, 7, 2017
5NWM
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INSIGHT INTO THE MOLECULAR RECOGNITION MECHANISM OF THE COACTIVATOR NCOA1 BY STAT6
Descriptor:Nuclear receptor coactivator 1, Signal transducer and activator of transcription 6
Authors:Russo, L., Becker, S., Griesinger, C.
Deposit date:2017-05-06
Release date:2017-12-06
Last modified:2017-12-13
Method:SOLUTION NMR
Cite:Insight into the molecular recognition mechanism of the coactivator NCoA1 by STAT6.
Sci Rep, 7, 2017
5JDP
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E73V MUTANT OF THE HUMAN VOLTAGE-DEPENDENT ANION CHANNEL
Descriptor:Voltage-dependent anion-selective channel protein 1
Authors:Jaremko, M., Jaremko, L., Villinger, S., Schmidt, C., Giller, K., Griesinger, C., Becker, S., Zweckstetter, M.
Deposit date:2016-04-17
Release date:2016-08-10
Last modified:2016-08-31
Method:SOLUTION NMR
Cite:High-Resolution NMR Determination of the Dynamic Structure of Membrane Proteins.
Angew.Chem.Int.Ed.Engl., 55, 2016
5FQ1
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STRUCTURE OF THE CYTOPLASMIC PAS DOMAIN OF THE GEOBACILLUS THERMODENITRIFICANS HISTIDINE KINASE CITA
Descriptor:HISTIDINE KINASE, GLYCEROL, PHOSPHATE ION
Authors:Schomburg, B., Giller, K., Becker, S.
Deposit date:2015-12-03
Release date:2017-01-11
Last modified:2017-03-01
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Cryogenic optical localization provides 3D protein structure data with Angstrom resolution.
Nat. Methods, 14, 2017
5ABS
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CRYSTAL STRUCTURE OF THE C-TERMINAL COILED-COIL DOMAIN OF CIN85 IN SPACE GROUP P321
Descriptor:SH3 DOMAIN-CONTAINING KINASE-BINDING PROTEIN 1, ZINC ION
Authors:Wong, L., Habeck, M., Griesinger, C., Becker, S.
Deposit date:2015-08-07
Release date:2016-07-13
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:The Adaptor Protein Cin85 Assembles Intracellular Signaling Clusters for B Cell Activation.
Sci.Signal., 9, 2016
4YXS
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CAMP-DEPENDENT PROTEIN KINASE PKA CATALYTIC SUBUNIT WITH PKI-5-24
Descriptor:cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, N-BENZYL-9H-PURIN-6-AMINE
Authors:Schiffer, A., Wendt, K.U.
Deposit date:2015-03-23
Release date:2015-05-20
Last modified:2015-06-03
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:A combination of spin diffusion methods for the determination of protein-ligand complex structural ensembles.
Angew.Chem.Int.Ed.Engl., 54, 2015
4YXR
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CRYSTAL STRUCTURE OF PKA IN COMPLEX WITH INHIBITOR.
Descriptor:cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, 3-methyl-2H-indazole
Authors:Schiffer, A., Wendt, K.U.
Deposit date:2015-03-23
Release date:2015-05-27
Last modified:2015-06-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:A combination of spin diffusion methods for the determination of protein-ligand complex structural ensembles.
Angew.Chem.Int.Ed.Engl., 54, 2015
4UN2
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CRYSTAL STRUCTURE OF THE UBA DOMAIN OF DSK2 IN COMPLEX WITH UBIQUITIN
Descriptor:UBIQUITIN, UBIQUITIN DOMAIN-CONTAINING PROTEIN DSK2
Authors:Michielssens, S., Peters, J.H., Ban, D., Pratihar, S., Seeliger, D., Sharma, M., Giller, K., Sabo, T.M., Becker, S., Lee, D., Griesinger, C., de Groot, B.L.
Deposit date:2014-05-23
Release date:2014-08-27
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:A Designed Conformational Shift to Control Protein Binding Specificity.
Angew.Chem.Int.Ed.Engl., 53, 2014
4C4Z
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CRYSTAL STRUCTURE OF HUMAN BIFUNCTIONAL EPOXIDE HYDROXYLASE 2 COMPLEXED WITH A8
Descriptor:BIFUNCTIONAL EPOXIDE HYDROLASE 2, 1-ethyl-3-naphthalen-1-ylurea
Authors:Pilger, J., Mazur, A., Monecke, P., Schreuder, H., Elshorst, B., Langer, T., Schiffer, A., Krimm, I., Wegstroth, M., Lee, D., Hessler, G., Wendt, K.-U., Becker, S., Griesinger, C.
Deposit date:2013-09-09
Release date:2014-10-01
Last modified:2015-06-10
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:A Combination of Spin Diffusion Methods for the Determination of Protein-Ligand Complex Structural Ensembles.
Angew.Chem.Int.Ed.Engl., 54, 2015
4C4Y
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CRYSTAL STRUCTURE OF HUMAN BIFUNCTIONAL EPOXIDE HYDROXYLASE 2 COMPLEXED WITH A4
Descriptor:BIFUNCTIONAL EPOXIDE HYDROLASE 2, 1-(3-chlorophenyl)-3-(2-methoxyethyl)urea
Authors:Pilger, J., Mazur, A., Monecke, P., Schreuder, H., Elshorst, B., Langer, T., Schiffer, A., Krimm, I., Wegstroth, M., Lee, D., Hessler, G., Wendt, K.-U., Becker, S., Griesinger, C.
Deposit date:2013-09-09
Release date:2014-10-01
Last modified:2015-06-10
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:A Combination of Spin Diffusion Methods for the Determination of Protein-Ligand Complex Structural Ensembles.
Angew.Chem.Int.Ed.Engl., 54, 2015
4C4X
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CRYSTAL STRUCTURE OF HUMAN BIFUNCTIONAL EPOXIDE HYDROXYLASE 2 COMPLEXED WITH C9
Descriptor:BIFUNCTIONAL EPOXIDE HYDROLASE 2, 3-(3,4-dichlorophenyl)-1,1-dimethyl-urea
Authors:Pilger, J., Mazur, A., Monecke, P., Schreuder, H., Elshorst, B., Langer, T., Schiffer, A., Krimm, I., Wegstroth, M., Lee, D., Hessler, G., Wendt, K.-U., Becker, S., Griesinger, C.
Deposit date:2013-09-09
Release date:2014-10-01
Last modified:2015-06-10
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:A Combination of Spin Diffusion Methods for the Determination of Protein-Ligand Complex Structural Ensembles.
Angew.Chem.Int.Ed.Engl., 54, 2015
3DNE
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CAMP-DEPENDENT PROTEIN KINASE PKA CATALYTIC SUBUNIT WITH PKI-5-24
Descriptor:cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, 3-pyridin-4-yl-1H-indazole
Authors:Schiffer, A., Wendt, K.U.
Deposit date:2008-07-02
Release date:2009-06-23
Last modified:2013-10-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystallography-independent determination of ligand binding modes
Angew.Chem.Int.Ed.Engl., 47, 2008
3DND
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CAMP-DEPENDENT PROTEIN KINASE PKA CATALYTIC SUBUNIT WITH PKI-5-24
Descriptor:cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, 5-benzyl-1,3-thiazol-2-amine
Authors:Schiffer, A., Wendt, K.U.
Deposit date:2008-07-02
Release date:2009-06-23
Last modified:2013-10-09
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Crystallography-independent determination of ligand binding modes
Angew.Chem.Int.Ed.Engl., 47, 2008
2X9C
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CRYSTAL STRUCTURE OF A SOLUBLE PRGI MUTANT FROM SALMONELLA TYPHIMURIUM
Descriptor:PROTEIN PRGI
Authors:Poyraz, O., Schmidt, H., Seidel, K., Delissen, F., Ader, C., Tenenboim, H., Goosmann, C., Laube, B., Thuenemann, A.F., Zychlinsky, A., Baldus, M., Lange, A., Griesinger, C., Kolbe, M.
Deposit date:2010-03-15
Release date:2010-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Protein Refolding is Required for Assembly of the Type Three Secretion Needle
Nat.Struct.Mol.Biol., 17, 2010
2W0N
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PLASTICITY OF PAS DOMAIN AND POTENTIAL ROLE FOR SIGNAL TRANSDUCTION IN THE HISTIDINE-KINASE DCUS
Descriptor:SENSOR PROTEIN DCUS
Authors:Etzkorn, M., Kneuper, H., Duennwald, P., Vijayan, V., Kraemer, J., Griesinger, C., Becker, S., Unden, G., Baldus, M.
Deposit date:2008-08-19
Release date:2008-09-30
Last modified:2013-07-24
Method:SOLID-STATE NMR
Cite:Plasticity of the Pas Domain and a Potential Role for Signal Transduction in the Histidine Kinase Dcus.
Nat.Struct.Mol.Biol., 15, 2008
2V9A
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STRUCTURE OF CITRATE-FREE PERIPLASMIC DOMAIN OF SENSOR HISTIDINE KINASE CITA
Descriptor:SENSOR KINASE CITA
Authors:Sevvana, M., Vijayan, V., Zweckstetter, M., Reinelt, S., Madden, D.R., Sheldrick, G.M., Bott, M., Griesinger, C., Becker, S.
Deposit date:2007-08-23
Release date:2008-03-25
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:A Ligand-Induced Switch in the Periplasmic Domain of Sensor Histidine Kinase Cita.
J.Mol.Biol., 377, 2008
2V3L
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ORIENTATIONAL AND DYNAMICAL HETEROGENEITY OF RHODAMINE 6G TERMINALLY ATTACHED TO A DNA HELIX
Descriptor:5'-D(*GP*AP*AP*TP*GP*GP*CP*GP*AP*AP *TP*GP*GP*CP*GP*CP*TP*TP*TP*G)-3', 5'-D(*CP*AP*AP*AP*GP*CP*GP*CP*CP*AP *TP*TP*CP*GP*CP*CP*AP*TP*TP*C)-3', RHODAMINE 6G
Authors:Neubauer, H., Gaiko, N., Berger, S., Schaffer, J., Eggeling, C., Tuma, J., Verdier, L., Seidel, C.A.M., Griesinger, C., Volkmer, A.
Deposit date:2007-06-18
Release date:2007-10-09
Last modified:2017-04-19
Method:SOLUTION NMR
Cite:Orientational and Dynamical Heterogeneity of Rhodamine 6G Terminally Attached to a DNA Helix Revealed by NMR and Single-Molecule Fluorescence Spectroscopy.
J.Am.Chem.Soc., 129, 2007
2N64
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NMR STRUCTURE OF THE C-TERMINAL COILED-COIL DOMAIN OF CIN85
Descriptor:SH3 domain-containing kinase-binding protein 1
Authors:Habeck, M., Becker, S., Griesinger, C., Wong, L.E.
Deposit date:2015-08-11
Release date:2016-07-13
Method:SOLUTION NMR
Cite:The adaptor protein CIN85 assembles intracellular signaling clusters for B cell activation.
Sci.Signal., 9, 2016
2MWH
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NMR SOLUTION STRUCTURE OF LIGAND-FREE OAA
Descriptor:Anti-HIV lectin OAA
Authors:Lee, D., Carneiro, M.G., Koharudin, L.M., Griesinger, C., Gronenborn, A.M., Ban, D., Sabo, T., Trigo-Mourino, P., Mazur, A.
Deposit date:2014-11-10
Release date:2015-04-22
Last modified:2015-06-10
Method:SOLUTION NMR
Cite:Sampling of Glycan-Bound Conformers by the Anti-HIV Lectin Oscillatoria agardhii agglutinin in the Absence of Sugar.
Angew.Chem.Int.Ed.Engl., 54, 2015
2M97
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OPTIMIZED RATIOMETRIC CALCIUM SENSORS FOR FUNCTIONAL IN VIVO IMAGING OF NEURONS AND T-LYMPHOCYTES
Descriptor:Optimized Ratiometric Calcium Sensor
Authors:Russo, L., Becker, S., Griesinger, C.
Deposit date:2013-06-04
Release date:2014-01-01
Last modified:2014-02-12
Method:SOLUTION NMR
Cite:Optimized ratiometric calcium sensors for functional in vivo imaging of neurons and T lymphocytes.
Nat.Methods, 11, 2014
2LPZ
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ATOMIC MODEL OF THE TYPE-III SECRETION SYSTEM NEEDLE
Descriptor:Protein prgI
Authors:Loquet, A., Sgourakis, N.G., Gupta, R., Giller, K., Riedel, D., Goosmann, C., Griesinger, C., Kolbe, M.G., Baker, D., Becker, S., Lange, A.
Deposit date:2012-02-21
Release date:2012-05-16
Last modified:2012-06-27
Method:SOLID-STATE NMR
Cite:Atomic model of the type III secretion system needle.
Nature, 486, 2012
2LGC
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JOINT NMR AND X-RAY REFINEMENT REVEALS THE STRUCTURE OF A NOVEL DIBENZO[A,D]CYCLOHEPTENONE INHIBITOR/P38 MAP KINASE COMPLEX IN SOLUTION
Descriptor:Mitogen-activated protein kinase 14
Authors:Habeck, M.
Deposit date:2011-07-25
Release date:2012-07-25
Method:SOLUTION NMR
Cite:Inferential NMR/X-ray-based structure determination of a dibenzo[a,d]cycloheptenone inhibitor-p38alpha MAP kinase complex in solution
Angew.Chem.Int.Ed.Engl., 51, 2012
2LEV
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STRUCTURE OF THE DNA COMPLEX OF THE C-TERMINAL DOMAIN OF LER
Descriptor:Ler, DNA (5'-D(*GP*CP*GP*AP*TP*AP*AP*TP*TP*GP*AP*TP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*AP*TP*CP*AP*AP*TP*TP*AP*TP*CP*GP*C)-3')
Authors:Cordeiro, T.N., Schimdt, H., Madrid, C., Juarez, A., Bernado, P., Grisienger, C., Garcia, J., Pons, M.
Deposit date:2011-06-23
Release date:2011-12-07
Method:SOLUTION NMR, SOLUTION SCATTERING
Cite:Indirect DNA Readout by an H-NS Related Protein: Structure of the DNA Complex of the C-Terminal Domain of Ler.
Plos Pathog., 7, 2011
2L8I
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A BIOCOMPATIBLE BACKBONE MODIFICATION? - STRUCTURE AND DYNAMICS OF A TRIAZOLE-LINKED DNA DUPLEX
Descriptor:DNA (5'-D(*GP*CP*TP*GP*CP*AP*AP*AP*CP*GP*TP*CP*G)-3'), DNA (5'-D(*CP*GP*AP*CP*G*(2L8)P*TP*GP*CP*AP*GP*C)-3')
Authors:El-Sagheer, A., Brown, T., Ernsting, N., Dehmel, L., Griesinger, C., Mugge, C.
Deposit date:2011-01-13
Release date:2011-12-28
Method:SOLUTION NMR
Cite:Structure and Dynamics of Triazole-Linked DNA: Biocompatibility Explained.
Chemistry, 17, 2011
2KV7
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NMR SOLUTION STRUCTURE OF A SOLUBLE PRGI MUTANT FROM SALMONELLA TYPHIMURIUM
Descriptor:Protein prgI
Authors:Schmidt, H., Poyraz, O., Seidel, K., Delissen, F., Ader, C., Tenenboim, H., Goosmann, C., Laube, B., Thuenemann, A.F., Zychlinski, A., Baldus, M., Lange, A., Griesinger, C., Kolbe, M.
Deposit date:2010-03-09
Release date:2010-06-16
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Protein refolding is required for assembly of the type three secretion needle
Nat.Struct.Mol.Biol., 2010
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