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2K8P
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CHARACTERISATION OF THE STRUCTURAL FEATURES AND INTERACTIONS OF SCLEROSTIN: MOLECULAR INSIGHT INTO A KEY REGULATOR OF WNT-MEDIATED BONE FORMATION
Descriptor:Sclerostin
Authors:Veverka, V., Henry, A.J., Slocombe, P.M., Ventom, A., Mulloy, B., Muskett, F.W., Muzylak, M., Greenslade, K., Moore, A., Zhang, L., Gong, J., Qian, X., Paszty, C., Taylor, R.J., Robinson, M.K., Carr, M.D.
Deposit date:2008-09-18
Release date:2009-02-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Characterization of the Structural Features and Interactions of Sclerostin: Molecular insight into a key regulator of Wnt-mediated bone formation
J.Biol.Chem., 284, 2009
6FGB
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HUMAN FCRN EXTRA-CELLULAR DOMAIN COMPLEXED WITH FAB FRAGMENT OF ROZANOLIXIZUMAB
Descriptor:IgG receptor FcRn large subunit p51, Beta-2-microglobulin, 1519.g57- Light chain, ...
Authors:Sarkar, K., Ceska, T., Meier, C.
Deposit date:2018-01-10
Release date:2018-08-29
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Generation and characterization of a high affinity anti-human FcRn antibody, rozanolixizumab, and the effects of different molecular formats on the reduction of plasma IgG concentration.
MAbs, 10, 2018