Author results

3J9S
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SINGLE PARTICLE CRYO-EM STRUCTURE OF ROTAVIRUS VP6 AT 2.6 ANGSTROM RESOLUTION
Descriptor:Intermediate capsid protein VP6, ZINC ION, CHLORIDE ION, ...
Authors:Grant, T., Grigorieff, N.
Deposit date:2015-02-19
Release date:2015-03-11
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Measuring the optimal exposure for single particle cryo-EM using a 2.6 angstrom reconstruction of rotavirus VP6.
Elife, 4, 2015
2VY9
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MOLECULAR ARCHITECTURE OF THE STRESSOSOME, A SIGNAL INTEGRATION AND TRANSDUCTION HUB
Descriptor:ANTI-SIGMA-FACTOR ANTAGONIST
Authors:Marles-Wright, J., Grant, T., Delumeau, O., van Duinen, G., Firbank, S.J., Lewis, P.J., Murray, J.W., Newman, J.A., Quin, M.B., Race, P.R., Rohou, A., Tichelaar, W., van Heel, M., Lewis, R.J.
Deposit date:2008-07-21
Release date:2008-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular Architecture of the "Stressosome," a Signal Integration and Transduction Hub
Science, 322, 2008
5A22
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STRUCTURE OF THE L PROTEIN OF VESICULAR STOMATITIS VIRUS FROM ELECTRON CRYOMICROSCOPY
Descriptor:VESICULAR STOMATITIS VIRUS L POLYMERASE, ZINC ION
Authors:Liang, B., Li, Z., Jenni, S., Rameh, A.A., Morin, B.M., Grant, T., Grigorieff, N., Harrison, S.C., Whelan, S.P.J.
Deposit date:2015-05-06
Release date:2015-08-19
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of the L Protein of Vesicular Stomatitis Virus from Electron Cryomicroscopy.
Cell(Cambridge,Mass.), 162, 2015
5B3J
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ACTIVATION OF NMDA RECEPTORS AND THE MECHANISM OF INHIBITION BY IFENPRODIL
Descriptor:NMDA glutamate receptor subunit, Glutamate receptor ionotropic, NMDA 2B, ...
Authors:Tajima, N., Karakas, E., Grant, T., Simorowski, N., Diaz-Avalos, R., Grigorieff, N., Furukawa, H.
Deposit date:2016-03-01
Release date:2016-05-11
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Activation of NMDA receptors and the mechanism of inhibition by ifenprodil
Nature, 534, 2016
5FXG
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GLUN1B-GLUN2B NMDA RECEPTOR IN ACTIVE CONFORMATION
Descriptor:N-METHYL-D-ASPARTATE RECEPTOR GLUN1, N-METHYL-D-ASPARTATE RECEPTOR GLUN2B
Authors:Tajima, N., Karakas, E., Grant, T., Simorowski, N., Diaz-Avalos, R., Grigorieff, N., Furukawa, H.
Deposit date:2016-03-02
Release date:2016-05-11
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:Activation of Nmda Receptors and the Mechanism of Inhibition by Ifenprodil.
Nature, 534, 2016
5FXH
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GLUN1B-GLUN2B NMDA RECEPTOR IN NON-ACTIVE-1 CONFORMATION
Descriptor:N-METHYL-D-ASPARTATE RECEPTOR GLUN1, N-METHYL-D-ASPARTATE RECEPTOR GLUN2B
Authors:Tajima, N., Karakas, E., Grant, T., Simorowski, N., Diaz-Avalos, R., Grigorieff, N., Furukawa, H.
Deposit date:2016-03-02
Release date:2016-05-11
Last modified:2017-04-19
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Activation of Nmda Receptors and the Mechanism of Inhibition by Ifenprodil.
Nature, 534, 2016
5FXI
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GLUN1B-GLUN2B NMDA RECEPTOR STRUCTURE IN NON-ACTIVE-2 CONFORMATION
Descriptor:N-METHYL-D-ASPARTATE RECEPTOR GLUN1, N-METHYL-D-ASPARTATE RECEPTOR GLUN2B
Authors:Tajima, N., Karakas, E., Grant, T., Simorowski, N., Diaz-Avalos, R., Grigorieff, N., Furukawa, H.
Deposit date:2016-03-02
Release date:2016-05-11
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (6.4 Å)
Cite:Activation of Nmda Receptors and the Mechanism of Inhibition by Ifenprodil.
Nature, 534, 2016
5FXJ
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GLUN1B-GLUN2B NMDA RECEPTOR STRUCTURE-CLASS X
Descriptor:GLUTAMATE RECEPTOR IONOTROPIC, NMDA 1, NMDA 2B
Authors:Tajima, N., Karakas, E., Grant, T., Simorowski, N., Diaz-Avalos, R., Grigorieff, N., Furukawa H, H.
Deposit date:2016-03-02
Release date:2016-05-25
Last modified:2016-06-15
Method:ELECTRON MICROSCOPY (6.5 Å)
Cite:Activation of Nmda Receptors and the Mechanism of Inhibition by Ifenprodil.
Nature, 534, 2016
5FXK
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GLUN1B-GLUN2B NMDA RECEPTOR STRUCTURE-CLASS Y
Descriptor:N-METHYL-D-ASPARTATE RECEPTOR GLUN1, N-METHYL-D-ASPARTATE RECEPTOR GLUN2B
Authors:Tajima, N., Karakas, E., Grant, T., Simorowski, N., Diaz-Avalos, R., Grigorieff, N., Furukawa, H.
Deposit date:2016-03-02
Release date:2016-05-11
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (6.4 Å)
Cite:Activation of Nmda Receptors and the Mechanism of Inhibition by Ifenprodil.
Nature, 534, 2016
5JUO
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SACCHAROMYCES CEREVISIAE 80S RIBOSOME BOUND WITH ELONGATION FACTOR EEF2-GDP-SORDARIN AND TAURA SYNDROME VIRUS IRES, STRUCTURE I (FULLY ROTATED 40S SUBUNIT)
Descriptor:18S ribosomal RNA, 25S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Abeyrathne, P., Koh, C.S., Grant, T., Grigorieff, N., Korostelev, A.A.
Deposit date:2016-05-10
Release date:2016-10-05
Last modified:2017-09-13
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome.
Elife, 5, 2016
5JUP
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SACCHAROMYCES CEREVISIAE 80S RIBOSOME BOUND WITH ELONGATION FACTOR EEF2-GDP-SORDARIN AND TAURA SYNDROME VIRUS IRES, STRUCTURE II (MID-ROTATED 40S SUBUNIT)
Descriptor:18S ribosomal RNA, 25S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Abeyrathne, P., Koh, C.S., Grant, T., Grigorieff, N., Korostelev, A.A.
Deposit date:2016-05-10
Release date:2016-10-05
Last modified:2017-09-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome.
Elife, 5, 2016
5JUS
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SACCHAROMYCES CEREVISIAE 80S RIBOSOME BOUND WITH ELONGATION FACTOR EEF2-GDP-SORDARIN AND TAURA SYNDROME VIRUS IRES, STRUCTURE III (MID-ROTATED 40S SUBUNIT)
Descriptor:18S ribosomal RNA, 25S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Abeyrathne, P., Koh, C.S., Grant, T., Grigorieff, N., Korostelev, A.A.
Deposit date:2016-05-10
Release date:2016-10-05
Last modified:2017-09-13
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome.
Elife, 5, 2016
5JUT
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SACCHAROMYCES CEREVISIAE 80S RIBOSOME BOUND WITH ELONGATION FACTOR EEF2-GDP-SORDARIN AND TAURA SYNDROME VIRUS IRES, STRUCTURE IV (ALMOST NON-ROTATED 40S SUBUNIT)
Descriptor:18S ribosomal RNA, 25S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Abeyrathne, P., Koh, C.S., Grant, T., Grigorieff, N., Korostelev, A.A.
Deposit date:2016-05-10
Release date:2016-10-05
Last modified:2017-09-13
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome.
Elife, 5, 2016
5JUU
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SACCHAROMYCES CEREVISIAE 80S RIBOSOME BOUND WITH ELONGATION FACTOR EEF2-GDP-SORDARIN AND TAURA SYNDROME VIRUS IRES, STRUCTURE V (LEAST ROTATED 40S SUBUNIT)
Descriptor:18S ribosomal RNA, 25S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Abeyrathne, P., Koh, C.S., Grant, T., Grigorieff, N., Korostelev, A.A.
Deposit date:2016-05-10
Release date:2016-10-05
Last modified:2017-09-13
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome.
Elife, 5, 2016
5U9F
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3.2 A CRYO-EM ARFA-RF2 RIBOSOME RESCUE COMPLEX (STRUCTURE II)
Descriptor:16S ribosomal RNA, 23S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Demo, G., Svidritskiy, E., Madireddy, R., Diaz-Avalos, R., Grant, T., Grigorieff, N., Sousa, D., Korostelev, A.A.
Deposit date:2016-12-16
Release date:2017-03-22
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Mechanism of ribosome rescue by ArfA and RF2.
Elife, 6, 2017
5U9G
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3.2 A CRYO-EM ARFA-RF2 RIBOSOME RESCUE COMPLEX (STRUCTURE I)
Descriptor:16S ribosomal RNA, 23S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Demo, G., Svidritskiy, E., Madireddy, R., Diaz-Avalos, R., Grant, T., Grigorieff, N., Sousa, D., Korostelev, A.A.
Deposit date:2016-12-16
Release date:2017-03-22
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Mechanism of ribosome rescue by ArfA and RF2.
Elife, 6, 2017
6CNA
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GLUN1-GLUN2B NMDA RECEPTORS WITH EXON 5
Descriptor:Glutamate receptor ionotropic, NMDA 1, NMDA 2B, ...
Authors:Furukawa, H., Grant, T., Grigorieff, N.
Deposit date:2018-03-07
Release date:2018-10-03
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural Mechanism of Functional Modulation by Gene Splicing in NMDA Receptors.
Neuron, 98, 2018
6N1P
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DIHEDRAL OLIGOMERIC COMPLEX OF GYRA N-TERMINAL FRAGMENT WITH DNA, SOLVED BY CRYOEM IN C2 SYMMETRY
Descriptor:DNA gyrase subunit A, DNA (44-MER)
Authors:Soczek, K.M., Grant, T., Rosenthal, P.B., Mondragon, A.
Deposit date:2018-11-10
Release date:2018-12-05
Method:ELECTRON MICROSCOPY (6.35 Å)
Cite:CryoEM structures of open dimers of Gyrase A in complex with DNA illuminate mechanism of strand passage.
Elife, 7, 2018
6N1Q
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DIHEDRAL OLIGOMERIC COMPLEX OF GYRA N-TERMINAL FRAGMENT, SOLVED BY CRYOEM IN D2 SYMMETRY
Descriptor:DNA gyrase subunit A
Authors:Soczek, K.M., Grant, T., Rosenthal, P.B., Mondragon, A.
Deposit date:2018-11-10
Release date:2018-12-05
Method:ELECTRON MICROSCOPY (5.16 Å)
Cite:CryoEM structures of open dimers of Gyrase A in complex with DNA illuminate mechanism of strand passage.
Elife, 7, 2018
6N1R
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TETRAHEDRAL OLIGOMERIC COMPLEX OF GYRA N-TERMINAL FRAGMENT, SOLVED BY CRYOEM IN TETRAHEDRAL SYMMETRY
Descriptor:DNA gyrase subunit A
Authors:Soczek, K.M., Grant, T., Rosenthal, P.B., Mondragon, A.
Deposit date:2018-11-10
Release date:2018-12-05
Method:ELECTRON MICROSCOPY (4 Å)
Cite:CryoEM structures of open dimers of Gyrase A in complex with DNA illuminate mechanism of strand passage.
Elife, 7, 2018
5WAU
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CRYSTAL STRUCTURE OF CO-BOUND CYTOCHROME C OXIDASE DETERMINED BY SYNCHROTRON X-RAY CRYSTALLOGRAPHY AT 100 K
Descriptor:Cytochrome c oxidase subunit 1, Cytochrome c oxidase subunit 2, Cytochrome c oxidase subunit 3, ...
Authors:Fromme, R., Ishigami, I., Yeh, S.Y., Zatsepin, N., Grant, T., Fromme, P., Rousseau, D.
Deposit date:2017-06-27
Release date:2017-08-09
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of CO-bound cytochrome c oxidase determined by serial femtosecond X-ray crystallography at room temperature.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5XEZ
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STRUCTURE OF THE FULL-LENGTH GLUCAGON CLASS B G PROTEIN-COUPLED RECEPTOR
Descriptor:Glucagon receptor,Endolysin,Glucagon receptor, Antibody, mAb1, ...
Authors:Zhang, H., Qiao, A., Yang, D., Yang, L., Dai, A., de Graaf, C., Reedtz-Runge, S., Dharmarajan, V., Zhang, H., Han, G.W., Grant, T., Sierra, R., Weierstall, U., Nelson, G., Liu, W., Wu, Y., Ma, L., Cai, X., Lin, G., Wu, X., Geng, Z., Dong, Y., Song, G., Griffin, P., Lau, J., Cherezov, V., Yang, H., Hanson, M., Stevens, R., Jiang, H., Wang, M., Zhao, Q., Wu, B.
Deposit date:2017-04-06
Release date:2017-05-24
Last modified:2017-06-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the full-length glucagon class B G-protein-coupled receptor.
Nature, 546, 2017
5XF1
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STRUCTURE OF THE FULL-LENGTH GLUCAGON CLASS B G PROTEIN-COUPLED RECEPTOR
Descriptor:Glucagon receptor,Endolysin,Glucagon receptor, Antibody mAb1 Heavy chain, Antibody mAb1 Light chain, ...
Authors:Zhang, H., Qiao, A., Yang, D., Yang, L., Dai, A., de Graaf, C., Reedtz-Runge, S., Dharmarajan, V., Zhang, H., Han, G.W., Grant, T., Sierra, R., Weierstall, U., Nelson, G., Liu, W., Wu, Y., Ma, L., Cai, X., Lin, G., Wu, X., Geng, Z., Dong, Y., Song, G., Griffin, P., Lau, J., Cherezov, V., Yang, H., Hanson, M., Stevens, R., Jiang, H., Wang, M., Zhao, Q., Wu, B.
Deposit date:2017-04-06
Release date:2017-05-24
Last modified:2017-06-14
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Structure of the full-length glucagon class B G-protein-coupled receptor.
Nature, 546, 2017
6B5X
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BETA-LACTAMASE, UNMIXED SHARDS CRYSTAL FORM
Descriptor:Beta-lactamase, PHOSPHATE ION
Authors:Pandey, S.
Deposit date:2017-09-29
Release date:2018-06-27
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Enzyme intermediates captured "on the fly" by mix-and-inject serial crystallography.
BMC Biol., 16, 2018
6B5Y
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BETA-LACTAMASE, MIXED WITH CEFTRIAXONE, 30MS TIME POINT, SHARDS CRYSTAL FORM
Descriptor:Beta-lactamase, PHOSPHATE ION, Ceftriaxone
Authors:Pandey, S., Schmidt, M.
Deposit date:2017-09-29
Release date:2018-06-27
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Enzyme intermediates captured "on the fly" by mix-and-inject serial crystallography.
BMC Biol., 16, 2018
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