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4EJ4
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BU of 4ej4 by Molmil
Structure of the delta opioid receptor bound to naltrindole
Descriptor: (4bS,8R,8aS,14bR)-7-(cyclopropylmethyl)-5,6,7,8,14,14b-hexahydro-4,8-methano[1]benzofuro[2,3-a]pyrido[4,3-b]carbazole-1,8a(9H)-diol, Delta-type opioid receptor, Lysozyme chimera
Authors:Granier, S, Manglik, A, Kruse, A.C, Kobilka, T.S, Thian, F.S, Weis, W.I, Kobilka, B.K.
Deposit date:2012-04-06
Release date:2012-05-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structure of the delta opioid receptor bound to naltrindole
Nature, 485, 2012
7R0C
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BU of 7r0c by Molmil
Structure of the AVP-V2R-arrestin2-ScFv30 complex
Descriptor: AVP, Arrestin2, ScFv30, ...
Authors:Bous, J, Fouillen, A, Trapani, S, Granier, S, Mouillac, B, Bron, P.
Deposit date:2022-02-01
Release date:2022-09-14
Method:ELECTRON MICROSCOPY (4.73 Å)
Cite:Structure of the vasopressin hormone-V2 receptor-beta-arrestin1 ternary complex.
Sci Adv, 8, 2022
7R0J
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BU of 7r0j by Molmil
Structure of the V2 receptor Cter-arrestin2-ScFv30 complex
Descriptor: Arrestin2, ScFv30, V2R Cter
Authors:Bous, J, Fouillen, A, Trapani, S, Granier, S, Mouillac, B, Bron, P.
Deposit date:2022-02-02
Release date:2022-09-14
Method:ELECTRON MICROSCOPY (4.23 Å)
Cite:Structure of the vasopressin hormone-V2 receptor-beta-arrestin1 ternary complex.
Sci Adv, 8, 2022
8CGE
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BU of 8cge by Molmil
The crystal structure of a cobalt-bound scFv reveals a Tetrameric polyHistidine motif (TetrHis)
Descriptor: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, COBALT (II) ION, SULFATE ION, ...
Authors:Healey, R.D, Hoh, F, Granier, S, Leyrat, C.
Deposit date:2023-02-03
Release date:2023-08-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure, dynamics and transferability of the metal-dependent polyhistidine tetramerization motif TetrHis for single-chain Fv antibodies.
Commun Chem, 6, 2023
5C1M
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BU of 5c1m by Molmil
Crystal structure of active mu-opioid receptor bound to the agonist BU72
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2R,3S,3aR,5aR,6R,11bR,11cS)-3a-methoxy-3,14-dimethyl-2-phenyl-2,3,3a,6,7,11c-hexahydro-1H-6,11b-(epiminoethano)-3,5a-methanonaphtho[2,1-g]indol-10-ol, CHOLESTEROL, ...
Authors:Huang, W.J, Manglik, A, Venkatakrishnan, A.J, Laeremans, T, Feinberg, E.N, Sanborn, A.L, Kato, H.E, Livingston, K.E, Thorsen, T.S, Kling, R, Granier, S, Gmeiner, P, Husbands, S.M, Traynor, J.R, Weis, W.I, Steyaert, J, Dror, R.O, Kobilka, B.K.
Deposit date:2015-06-15
Release date:2015-08-05
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structural insights into mu-opioid receptor activation.
Nature, 524, 2015
6G7O
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BU of 6g7o by Molmil
Crystal structure of human alkaline ceramidase 3 (ACER3) at 2.7 Angstrom resolution
Descriptor: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Alkaline ceramidase 3,Soluble cytochrome b562, CALCIUM ION, ...
Authors:Leyrat, C, Vasiliauskaite-Brooks, I, Healey, R.D, Sounier, R, Grison, C, Hoh, F, Basu, S, Granier, S.
Deposit date:2018-04-06
Release date:2019-01-02
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of a human intramembrane ceramidase explains enzymatic dysfunction found in leukodystrophy.
Nat Commun, 9, 2018
5OIY
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BU of 5oiy by Molmil
Structure of the HMPV P oligomerization domain at 2.2 A
Descriptor: Phosphoprotein
Authors:Renner, M, Paesen, G.C, Grison, C.M, Granier, S, Grimes, J.M, Leyrat, C.
Deposit date:2017-07-19
Release date:2017-11-15
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural dissection of human metapneumovirus phosphoprotein using small angle x-ray scattering.
Sci Rep, 7, 2017
5OIX
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BU of 5oix by Molmil
Structure of the HMPV P oligomerization domain at 1.6 A
Descriptor: GLYCEROL, Phosphoprotein
Authors:Renner, M, Paesen, G.C, Grison, C.M, Granier, S, Grimes, J.M, Leyrat, C.
Deposit date:2017-07-19
Release date:2017-11-15
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Structural dissection of human metapneumovirus phosphoprotein using small angle x-ray scattering.
Sci Rep, 7, 2017
7P8S
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BU of 7p8s by Molmil
Crystal Structure of leukotoxin LukE from Staphylococcus aureus at 1.9 Angstrom resolution
Descriptor: (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, HEXAETHYLENE GLYCOL, Leucotoxin LukEv, ...
Authors:Lambey, P, Hoh, F, Granier, S, Leyrat, C.
Deposit date:2021-07-23
Release date:2022-04-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insights into recognition of chemokine receptors by Staphylococcus aureus leukotoxins.
Elife, 11, 2022
7P8U
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BU of 7p8u by Molmil
Crystal Structure of leukotoxin LukE from Staphylococcus aureus in complex with p-cresyl sulfate
Descriptor: (4-methylphenyl) hydrogen sulfate, DI(HYDROXYETHYL)ETHER, IMIDAZOLE, ...
Authors:Lambey, P, Hoh, F, Peysson, F, Granier, S, Leyrat, C.
Deposit date:2021-07-23
Release date:2022-04-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural insights into recognition of chemokine receptors by Staphylococcus aureus leukotoxins.
Elife, 11, 2022
7P8X
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BU of 7p8x by Molmil
Crystal Structure of leukotoxin LukE from Staphylococcus aureus in complex with a doubly sulfated CCR2 N-terminal peptide
Descriptor: C-C chemokine receptor type 2, IMIDAZOLE, Leucotoxin LukEv, ...
Authors:Lambey, P, Hoh, F, Peysson, F, Granier, S, Leyrat, C.
Deposit date:2021-07-23
Release date:2022-04-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural insights into recognition of chemokine receptors by Staphylococcus aureus leukotoxins.
Elife, 11, 2022
7P8T
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BU of 7p8t by Molmil
Crystal Structure of leukotoxin LukE from Staphylococcus aureus at 1.5 Angstrom resolution
Descriptor: CHLORIDE ION, Leucotoxin LukEv
Authors:Lambey, P, Hoh, F, Granier, S, Leyrat, C.
Deposit date:2021-07-23
Release date:2022-04-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.459 Å)
Cite:Structural insights into recognition of chemokine receptors by Staphylococcus aureus leukotoxins.
Elife, 11, 2022
7P93
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BU of 7p93 by Molmil
Crystal Structure of leukotoxin LukE from Staphylococcus aureus in complex with a sulfated ACKR1 N-terminal peptide
Descriptor: Atypical chemokine receptor 1, Leucotoxin LukEv
Authors:Lambey, P, Hoh, F, Peysson, F, Granier, S, Leyrat, C.
Deposit date:2021-07-23
Release date:2022-04-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural insights into recognition of chemokine receptors by Staphylococcus aureus leukotoxins.
Elife, 11, 2022
4DKL
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BU of 4dkl by Molmil
Crystal structure of the mu-opioid receptor bound to a morphinan antagonist
Descriptor: CHLORIDE ION, CHOLESTEROL, Mu-type opioid receptor, ...
Authors:Manglik, A, Kruse, A.C, Kobilka, T.S, Thian, F.S, Mathiesen, J.M, Sunahara, R.K, Pardo, L, Weis, W.I, Kobilka, B.K, Granier, S.
Deposit date:2012-02-03
Release date:2012-03-21
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the {mu}-opioid receptor bound to a morphinan antagonist.
Nature, 485, 2012
6YXG
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BU of 6yxg by Molmil
Cryogenic human adiponectin receptor 2 (ADIPOR2) with Tb-XO4 ligand determined by Serial Crystallography (SSX) using CrystalDirect
Descriptor: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Adiponectin receptor protein 2, OLEIC ACID, ...
Authors:Healey, R.D, Basu, S, Humm, A.S, Leyrat, C, Dupeux, F, Pica, A, Granier, S, Marquez, J.A.
Deposit date:2020-05-01
Release date:2021-05-12
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:An automated platform for structural analysis of membrane proteins through serial crystallography.
Cell Rep Methods, 1, 2021
6YXF
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BU of 6yxf by Molmil
Cryogenic human adiponectin receptor 2 (ADIPOR2) with Gd-DO3 ligand determined by Serial Crystallography (SSX) using CrystalDirect
Descriptor: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 10-((2R)-2-HYDROXYPROPYL)-1,4,7,10-TETRAAZACYCLODODECANE 1,4,7-TRIACETIC ACID, Adiponectin receptor protein 2, ...
Authors:Healey, R.D, Basu, S, Humm, A.S, Leyrat, C, Dupeux, F, Pica, A, Granier, S, Marquez, J.A.
Deposit date:2020-05-01
Release date:2021-05-12
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.025 Å)
Cite:An automated platform for structural analysis of membrane proteins through serial crystallography.
Cell Rep Methods, 1, 2021
6YX9
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BU of 6yx9 by Molmil
Cryogenic human adiponectin receptor 2 (ADIPOR2) at 2.4 A resolution determined by Serial Crystallography (SSX) using CrystalDirect
Descriptor: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Adiponectin receptor protein 2, GLYCEROL, ...
Authors:Healey, R.D, Basu, S, Humm, A.S, Leyrat, C, Dupeux, F, Pica, A, Granier, S, Marquez, J.A.
Deposit date:2020-04-30
Release date:2021-05-12
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.404 Å)
Cite:An automated platform for structural analysis of membrane proteins through serial crystallography.
Cell Rep Methods, 1, 2021
6YXH
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BU of 6yxh by Molmil
Cryogenic human alkaline ceramidase 3 (ACER3) at 2.6 A resolution determined by Serial Crystallography (SSX) using CrystalDirect
Descriptor: Alkaline ceramidase 3, CALCIUM ION, MAGNESIUM ION, ...
Authors:Healey, R.D, Basu, S, Humm, A.S, Leyrat, C, Dupeux, F, Pica, A, Granier, S, Marquez, J.A.
Deposit date:2020-05-01
Release date:2021-05-12
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:An automated platform for structural analysis of membrane proteins through serial crystallography.
Cell Rep Methods, 1, 2021
6YXD
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BU of 6yxd by Molmil
Room temperature structure of human adiponectin receptor 2 (ADIPOR2) at 2.9 A resolution determined by Serial Crystallography (SSX) using CrystalDirect
Descriptor: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Adiponectin receptor protein 2, GLYCEROL, ...
Authors:Healey, R.D, Basu, S, Humm, A.S, Leyrat, C, Dupeux, F, Pica, A, Granier, S, Marquez, J.A.
Deposit date:2020-05-01
Release date:2021-05-12
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:An automated platform for structural analysis of membrane proteins through serial crystallography.
Cell Rep Methods, 1, 2021
7BB7
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BU of 7bb7 by Molmil
AVP-V2R-Galphas-beta1-gamma2-Nb35(T state)
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
Authors:Bous, J, Mouillac, B, Bron, P, Granier, S, Floquet, N, Leyrat, C.
Deposit date:2020-12-17
Release date:2021-06-02
Last modified:2021-06-30
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Cryo-electron microscopy structure of the antidiuretic hormone arginine-vasopressin V2 receptor signaling complex.
Sci Adv, 7, 2021
7BB6
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BU of 7bb6 by Molmil
AVP-V2R-Galphas-beta1-gamma2-Nb35 (L state)
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
Authors:Bous, J, Mouillac, B, Bron, P, Granier, S, Floquet, N, Leyrat, C.
Deposit date:2020-12-17
Release date:2021-06-02
Last modified:2021-06-30
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Cryo-electron microscopy structure of the antidiuretic hormone arginine-vasopressin V2 receptor signaling complex.
Sci Adv, 7, 2021
5LX9
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BU of 5lx9 by Molmil
CRYSTAL STRUCTURE OF HUMAN ADIPONECTIN RECEPTOR 2 IN COMPLEX WITH A C18 FREE FATTY ACID AT 2.4 ANGSTROM RESOLUTION
Descriptor: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, HUMAN ADIPONECTIN RECEPTOR 2, OLEIC ACID, ...
Authors:Vasiliauskaite-Brooks, I, Leyrat, C, Hoh, F, Granier, S.
Deposit date:2016-09-20
Release date:2017-03-22
Last modified:2017-04-12
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural insights into adiponectin receptors suggest ceramidase activity.
Nature, 6, 2017
5LXG
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BU of 5lxg by Molmil
Revised crystal structure of the human adiponectin receptor 1 in an open conformation
Descriptor: Adiponectin receptor protein 1, SULFATE ION, V REGION HEAVY CHAIN, ...
Authors:Leyrat, C, Vasiliauskaite-Brooks, I, Granier, S.
Deposit date:2016-09-21
Release date:2017-03-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:Structural insights into adiponectin receptors suggest ceramidase activity.
Nature, 6, 2017
5LXA
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BU of 5lxa by Molmil
CRYSTAL STRUCTURE OF HUMAN ADIPONECTIN RECEPTOR 2 IN COMPLEX WITH A C18 FREE FATTY ACID AT 3.0 ANGSTROM RESOLUTION
Descriptor: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Adiponectin receptor protein 2, Anti-CD30 moab Ki-4 scFv, ...
Authors:Vasiliauskaite-Brooks, I, Leyrat, C, Hoh, F, Granier, S.
Deposit date:2016-09-20
Release date:2017-03-22
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural insights into adiponectin receptors suggest ceramidase activity.
Nature, 6, 2017
5LWY
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BU of 5lwy by Molmil
Revised crystal structure of the human adiponectin receptor 2 in complex with a C18 free fatty acid
Descriptor: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Adiponectin receptor protein 2, GLYCEROL, ...
Authors:Leyrat, C, Vasiliauskaite-Brooks, I, Granier, S.
Deposit date:2016-09-19
Release date:2017-03-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural insights into adiponectin receptors suggest ceramidase activity.
Nature, 6, 2017

 

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