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4EJ4
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STRUCTURE OF THE DELTA OPIOID RECEPTOR BOUND TO NALTRINDOLE
Descriptor:Delta-type opioid receptor, Lysozyme chimera, (4bS,8R,8aS,14bR)-7-(cyclopropylmethyl)-5,6,7,8,14,14b-hexahydro-4,8-methano[1]benzofuro[2,3-a]pyrido[4,3-b]carbazole-1,8a(9H)-diol
Authors:Granier, S., Manglik, A., Kruse, A.C., Kobilka, T.S., Thian, F.S., Weis, W.I., Kobilka, B.K.
Deposit date:2012-04-06
Release date:2012-05-16
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structure of the delta opioid receptor bound to naltrindole
Nature, 485, 2012
6G7O
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CRYSTAL STRUCTURE OF HUMAN ALKALINE CERAMIDASE 3 (ACER3) AT 2.7 ANGSTROM RESOLUTION
Descriptor:Alkaline ceramidase 3,Soluble cytochrome b562, ZINC ION, SULFATE ION, ...
Authors:Leyrat, C., Vasiliauskaite-Brooks, I., Healey, R.D., Sounier, R., Grison, C., Hoh, F., Basu, S., Granier, S.
Deposit date:2018-04-06
Release date:2019-01-02
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of a human intramembrane ceramidase explains enzymatic dysfunction found in leukodystrophy.
Nat Commun, 9, 2018
4DKL
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CRYSTAL STRUCTURE OF THE MU-OPIOID RECEPTOR BOUND TO A MORPHINAN ANTAGONIST
Descriptor:Mu-type opioid receptor, lysozyme chimera, methyl 4-{[(5beta,6alpha)-17-(cyclopropylmethyl)-3,14-dihydroxy-4,5-epoxymorphinan-6-yl]amino}-4-oxobutanoate, ...
Authors:Manglik, A., Kruse, A.C., Kobilka, T.S., Thian, F.S., Mathiesen, J.M., Sunahara, R.K., Pardo, L., Weis, W.I., Kobilka, B.K., Granier, S.
Deposit date:2012-02-03
Release date:2012-03-21
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the {mu}-opioid receptor bound to a morphinan antagonist.
Nature, 485, 2012
5C1M
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CRYSTAL STRUCTURE OF ACTIVE MU-OPIOID RECEPTOR BOUND TO THE AGONIST BU72
Descriptor:Mu-type opioid receptor, Nanobody 39, (2S,3S,3aR,5aR,6R,11bR,11cS)-3a-methoxy-3,14-dimethyl-2-phenyl-2,3,3a,6,7,11c-hexahydro-1H-6,11b-(epiminoethano)-3,5a-methanonaphtho[2,1-g]indol-10-ol, ...
Authors:Huang, W.J., Manglik, A., Venkatakrishnan, A.J., Laeremans, T., Feinberg, E.N., Sanborn, A.L., Kato, H.E., Livingston, K.E., Thorsen, T.S., Kling, R., Granier, S., Gmeiner, P., Husbands, S.M., Traynor, J.R., Weis, W.I., Steyaert, J., Dror, R.O., Kobilka, B.K.
Deposit date:2015-06-15
Release date:2015-08-05
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural insights into mu-opioid receptor activation.
Nature, 524, 2015
5LWY
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REVISED CRYSTAL STRUCTURE OF THE HUMAN ADIPONECTIN RECEPTOR 2 IN COMPLEX WITH A C18 FREE FATTY ACID
Descriptor:Adiponectin receptor protein 2, V REGION HEAVY CHAIN, V REGION LIGHT CHAIN, ...
Authors:Leyrat, C., Vasiliauskaite-Brooks, I., Granier, S.
Deposit date:2016-09-19
Release date:2017-03-22
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural insights into adiponectin receptors suggest ceramidase activity.
Nature, 6, 2017
5LX9
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CRYSTAL STRUCTURE OF HUMAN ADIPONECTIN RECEPTOR 2 IN COMPLEX WITH A C18 FREE FATTY ACID AT 2.4 ANGSTROM RESOLUTION
Descriptor:HUMAN ADIPONECTIN RECEPTOR 2, single-chain variable fragment, ZINC ION, ...
Authors:Vasiliauskaite-Brooks, I., Leyrat, C., Hoh, F., Granier, S.
Deposit date:2016-09-20
Release date:2017-03-22
Last modified:2017-04-12
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural insights into adiponectin receptors suggest ceramidase activity.
Nature, 6, 2017
5LXA
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CRYSTAL STRUCTURE OF HUMAN ADIPONECTIN RECEPTOR 2 IN COMPLEX WITH A C18 FREE FATTY ACID AT 3.0 ANGSTROM RESOLUTION
Descriptor:Adiponectin receptor protein 2, Anti-CD30 moab Ki-4 scFv, ZINC ION, ...
Authors:Vasiliauskaite-Brooks, I., Leyrat, C., Hoh, F., Granier, S.
Deposit date:2016-09-20
Release date:2017-03-22
Last modified:2017-04-12
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural insights into adiponectin receptors suggest ceramidase activity.
Nature, 6, 2017
5LXG
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REVISED CRYSTAL STRUCTURE OF THE HUMAN ADIPONECTIN RECEPTOR 1 IN AN OPEN CONFORMATION
Descriptor:Adiponectin receptor protein 1, V REGION HEAVY CHAIN, V REGION LIGHT CHAIN, ...
Authors:Leyrat, C., Vasiliauskaite-Brooks, I., Granier, S.
Deposit date:2016-09-21
Release date:2017-03-22
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:Structural insights into adiponectin receptors suggest ceramidase activity.
Nature, 6, 2017
5OIX
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STRUCTURE OF THE HMPV P OLIGOMERIZATION DOMAIN AT 1.6 A
Descriptor:Phosphoprotein, GLYCEROL
Authors:Renner, M., Paesen, G.C., Grison, C.M., Granier, S., Grimes, J.M., Leyrat, C.
Deposit date:2017-07-19
Release date:2017-11-15
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Structural dissection of human metapneumovirus phosphoprotein using small angle x-ray scattering.
Sci Rep, 7, 2017
5OIY
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STRUCTURE OF THE HMPV P OLIGOMERIZATION DOMAIN AT 2.2 A
Descriptor:Phosphoprotein
Authors:Renner, M., Paesen, G.C., Grison, C.M., Granier, S., Grimes, J.M., Leyrat, C.
Deposit date:2017-07-19
Release date:2017-11-15
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural dissection of human metapneumovirus phosphoprotein using small angle x-ray scattering.
Sci Rep, 7, 2017
6DDE
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MU OPIOID RECEPTOR-GI PROTEIN COMPLEX
Descriptor:Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Koehl, A., Hu, H., Maeda, S., Manglik, A., Zhang, Y., Kobilka, B.K., Skiniotis, G., Weis, W.I.
Deposit date:2018-05-10
Release date:2018-06-13
Last modified:2018-07-04
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of the mu-opioid receptor-Giprotein complex.
Nature, 558, 2018
6DDF
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MU OPIOID RECEPTOR-GI PROTEIN COMPLEX
Descriptor:Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Koehl, A., Hu, H., Maeda, S., Manglik, A., Kobilka, B.K., Skiniotis, G., Weis, W.I.
Deposit date:2018-05-10
Release date:2018-06-13
Last modified:2018-07-04
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of the mu-opioid receptor-Giprotein complex.
Nature, 558, 2018
2JX4
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NMR STRUCTURE OF THE INTRACELLULAR LOOP (I3) OF THE VASOPRESSIN V2 RECEPTOR (GPCR)
Descriptor:Vasopressin V2 receptor
Authors:Bellot, G., Demene, H.
Deposit date:2007-11-06
Release date:2008-11-18
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the third intracellular loop of the vasopressin V2 receptor and conformational changes upon binding to gC1qR
To be Published