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6GWT
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CRYO-EM STRUCTURE OF AN E. COLI 70S RIBOSOME IN COMPLEX WITH RF3-GDPCP, RF1(GAQ) AND PINT-TRNA (STATE I)
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Graf, M., Huter, P., Maracci, C., Peterek, M., Rodnina, M.V., Wilson, D.N.
Deposit date:2018-06-25
Release date:2018-08-15
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Visualization of translation termination intermediates trapped by the Apidaecin 137 peptide during RF3-mediated recycling of RF1.
Nat Commun, 9, 2018
6GXM
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CRYO-EM STRUCTURE OF AN E. COLI 70S RIBOSOME IN COMPLEX WITH RF3-GDPCP, RF1(GAQ) AND PINT-TRNA (STATE II)
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Graf, M., Huter, P., Maracci, C., Peterek, M., Rodnina, M.V., Wilson, D.N.
Deposit date:2018-06-27
Release date:2018-08-22
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Visualization of translation termination intermediates trapped by the Apidaecin 137 peptide during RF3-mediated recycling of RF1.
Nat Commun, 9, 2018
6GXN
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CRYO-EM STRUCTURE OF AN E. COLI 70S RIBOSOME IN COMPLEX WITH RF3-GDPCP, RF1(GAQ) AND PINT-TRNA (STATE III)
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Graf, M., Huter, P., Maracci, C., Peterek, M., Rodnina, M.V., Wilson, D.N.
Deposit date:2018-06-27
Release date:2018-08-15
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Visualization of translation termination intermediates trapped by the Apidaecin 137 peptide during RF3-mediated recycling of RF1.
Nat Commun, 9, 2018
6GXO
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CRYO-EM STRUCTURE OF A ROTATED E. COLI 70S RIBOSOME IN COMPLEX WITH RF3-GDPCP, RF1(GAQ) AND P/E-TRNA (STATE IV)
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Graf, M., Huter, P., Maracci, C., Peterek, M., Rodnina, M.V., Wilson, D.N.
Deposit date:2018-06-27
Release date:2018-08-15
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Visualization of translation termination intermediates trapped by the Apidaecin 137 peptide during RF3-mediated recycling of RF1.
Nat Commun, 9, 2018
6GXP
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CRYO-EM STRUCTURE OF A ROTATED E. COLI 70S RIBOSOME IN COMPLEX WITH RF3-GDPCP(RF3-ONLY)
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Graf, M., Huter, P., Maracci, C., Peterek, M., Rodnina, M.V., Wilson, D.N.
Deposit date:2018-06-27
Release date:2018-08-15
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Visualization of translation termination intermediates trapped by the Apidaecin 137 peptide during RF3-mediated recycling of RF1.
Nat Commun, 9, 2018
5MLC
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CRYO-EM STRUCTURE OF THE SPINACH CHLOROPLAST RIBOSOME REVEALS THE LOCATION OF PLASTID-SPECIFIC RIBOSOMAL PROTEINS AND EXTENSIONS
Descriptor:23S ribosomal RNA, chloroplastic, 5S ribosomal RNA, ...
Authors:Graf, M., Arenz, S., Huter, P., Doenhoefer, A., Novacek, J., Wilson, D.N.
Deposit date:2016-12-06
Release date:2016-12-28
Last modified:2018-10-17
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structure of the spinach chloroplast ribosome reveals the location of plastid-specific ribosomal proteins and extensions.
Nucleic Acids Res., 45, 2017
5O2R
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CRYO-EM STRUCTURE OF THE PROLINE-RICH ANTIMICROBIAL PEPTIDE API137 BOUND TO THE TERMINATING RIBOSOME
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Graf, M., Berninghausen, O., Beckmann, R., Wilson, D.N.
Deposit date:2017-05-22
Release date:2017-07-26
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:An antimicrobial peptide that inhibits translation by trapping release factors on the ribosome.
Nat. Struct. Mol. Biol., 24, 2017
5F8K
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CRYSTAL STRUCTURE OF THE BAC7(1-16) ANTIMICROBIAL PEPTIDE BOUND TO THE THERMUS THERMOPHILUS 70S RIBOSOME
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Seefeldt, A.C., Graf, M., Perebaskine, N., Nguyen, F., Arenz, S., Mardirossian, M., Scocchi, M., Wilson, D.N., Innis, C.A.
Deposit date:2015-12-09
Release date:2016-02-03
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the mammalian antimicrobial peptide Bac7(1-16) bound within the exit tunnel of a bacterial ribosome.
Nucleic Acids Res., 44, 2016
5FDU
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CRYSTAL STRUCTURE OF THE METALNIKOWIN I ANTIMICROBIAL PEPTIDE BOUND TO THE THERMUS THERMOPHILUS 70S RIBOSOME
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Seefeldt, A.C., Graf, M., Perebaskine, N., Nguyen, F., Arenz, S., Mardirossian, M., Scocchi, M., Wilson, D.N., Innis, C.A.
Deposit date:2015-12-16
Release date:2016-01-27
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of the mammalian antimicrobial peptide Bac7(1-16) bound within the exit tunnel of a bacterial ribosome.
Nucleic Acids Res., 44, 2016
5FDV
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CRYSTAL STRUCTURE OF THE PYRRHOCORICIN ANTIMICROBIAL PEPTIDE BOUND TO THE THERMUS THERMOPHILUS 70S RIBOSOME
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Seefeldt, A.C., Graf, M., Perebaskine, N., Nguyen, F., Arenz, S., Mardirossian, M., Scocchi, M., Wilson, D.N., Innis, C.A.
Deposit date:2015-12-16
Release date:2016-01-27
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the mammalian antimicrobial peptide Bac7(1-16) bound within the exit tunnel of a bacterial ribosome.
Nucleic Acids Res., 44, 2016
6HA1
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CRYO-EM STRUCTURE OF A 70S BACILLUS SUBTILIS RIBOSOME TRANSLATING THE ERMD LEADER PEPTIDE IN COMPLEX WITH TELITHROMYCIN
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Crowe-McAuliffe, C., Graf, M., Huter, P., Abdelshahid, M., Novacek, J., Wilson, D.N.
Deposit date:2018-08-07
Release date:2018-08-29
Last modified:2018-09-12
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for antibiotic resistance mediated by theBacillus subtilisABCF ATPase VmlR.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6HA8
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CRYO-EM STRUCTURE OF THE ABCF PROTEIN VMLR BOUND TO THE BACILLUS SUBTILIS RIBOSOME
Descriptor:23S rRNA, 5S rRNA, 50S ribosomal protein L2, ...
Authors:Crowe-McAuliffe, C., Graf, M., Huter, P., Abdelshahid, M., Novacek, J., Wilson, D.N.
Deposit date:2018-08-07
Release date:2018-08-29
Last modified:2018-09-12
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis for antibiotic resistance mediated by theBacillus subtilisABCF ATPase VmlR.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4ZER
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CRYSTAL STRUCTURE OF THE ONC112 ANTIMICROBIAL PEPTIDE BOUND TO THE THERMUS THERMOPHILUS 70S RIBOSOME
Descriptor:23s ribosomal RNA, 5s ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Seefeldt, A.C., Nguyen, F., Antunes, S., Perebaskine, N., Graf, M., Arenz, S., Inampudi, K.K., Douat, C., Guichard, G., Wilson, D.N., Innis, C.A.
Deposit date:2015-04-20
Release date:2015-05-20
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The proline-rich antimicrobial peptide Onc112 inhibits translation by blocking and destabilizing the initiation complex.
Nat.Struct.Mol.Biol., 22, 2015
5JTE
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CRYO-EM STRUCTURE OF AN ERMBL-STALLED RIBOSOME IN COMPLEX WITH A-, P-, AND E-TRNA
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Arenz, S., Bock, L.V., Graf, M., Innis, C.A., Beckmann, R., Grubmueller, H., Vaiana, A.C., Wilson, D.N.
Deposit date:2016-05-09
Release date:2016-07-20
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:A combined cryo-EM and molecular dynamics approach reveals the mechanism of ErmBL-mediated translation arrest.
Nat Commun, 7, 2016
5JU8
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CRYO-EM STRUCTURE OF AN ERMBL-STALLED RIBOSOME IN COMPLEX WITH P-, AND E-TRNA
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Arenz, S., Bock, L.V., Graf, M., Innis, C.A., Beckmann, R., Grubmueller, H., Vaiana, A.C., Wilson, D.N.
Deposit date:2016-05-10
Release date:2016-07-20
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:A combined cryo-EM and molecular dynamics approach reveals the mechanism of ErmBL-mediated translation arrest.
Nat Commun, 7, 2016
5KCR
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CRYO-EM STRUCTURE OF THE ESCHERICHIA COLI 70S RIBOSOME IN COMPLEX WITH ANTIBIOTIC AVILAMYCIN C, MRNA AND P-SITE TRNA AT 3.6A RESOLUTION
Descriptor:23S Ribosomal RNA, 5S Ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Arenz, S., Juette, M.F., Graf, M., Nguyen, F., Huter, P., Polikanov, Y.S., Blanchard, S.C., Wilson, D.N.
Deposit date:2016-06-06
Release date:2016-08-17
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structures of the orthosomycin antibiotics avilamycin and evernimicin in complex with the bacterial 70S ribosome.
Proc.Natl.Acad.Sci.USA, 113, 2016
5KCS
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CRYO-EM STRUCTURE OF THE ESCHERICHIA COLI 70S RIBOSOME IN COMPLEX WITH ANTIBIOTIC EVERNIMYCIN, MRNA, TETM AND P-SITE TRNA AT 3.9A RESOLUTION
Descriptor:23S Ribosomal RNA, 5S Ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Arenz, S., Juette, M.F., Graf, M., Nguyen, F., Huter, P., Polikanov, Y.S., Blanchard, S.C., Wilson, D.N.
Deposit date:2016-06-06
Release date:2016-08-17
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structures of the orthosomycin antibiotics avilamycin and evernimicin in complex with the bacterial 70S ribosome.
Proc.Natl.Acad.Sci.USA, 113, 2016
2LUU
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NMR SOLUTION STRUCTURE OF MIDKINE-B, MDKB
Descriptor:Midkine-related growth factor Mdk2
Authors:Yang, D., Lim, J., Meng, D.
Deposit date:2012-06-21
Release date:2013-05-01
Method:SOLUTION NMR
Cite:Structure-function analysis of full-length midkine reveals novel residues important for heparin binding and zebrafish embryogenesis.
Biochem.J., 451, 2013
6ENF
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CRYO-EM STRUCTURE OF A POLYPROLINE-STALLED RIBOSOME IN THE ABSENCE OF EF-P
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Huter, P., Arenz, S., Wilson, D.N.
Deposit date:2017-10-04
Release date:2017-11-22
Last modified:2018-01-31
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural Basis for Polyproline-Mediated Ribosome Stalling and Rescue by the Translation Elongation Factor EF-P.
Mol. Cell, 68, 2017
6ENJ
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POLYPROLINE-STALLED RIBOSOME IN THE PRESENCE OF A+P SITE TRNA AND ELONGATION-FACTOR P (EF-P)
Descriptor:23S Ribosomal RNA, 5S Ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Huter, P., Wilson, D.N.
Deposit date:2017-10-05
Release date:2017-11-22
Last modified:2018-01-31
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural Basis for Polyproline-Mediated Ribosome Stalling and Rescue by the Translation Elongation Factor EF-P.
Mol. Cell, 68, 2017
6ENU
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POLYPROLINE-STALLED RIBOSOME IN THE PRESENCE OF ELONGATION-FACTOR P (EF-P)
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Huter, P., Arenz, S., Wilson, D.N.
Deposit date:2017-10-06
Release date:2017-11-22
Last modified:2018-01-31
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural Basis for Polyproline-Mediated Ribosome Stalling and Rescue by the Translation Elongation Factor EF-P.
Mol. Cell, 68, 2017
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