Author results

1S5O
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STRUCTURAL AND MUTATIONAL CHARACTERIZATION OF L-CARNITINE BINDING TO HUMAN CARNITINE ACETYLTRANSFERASE
Descriptor:carnitine acetyltransferase isoform 2, CARNITINE
Authors:Govindasamy, L., Kukar, T., Lian, W., Pedersen, B., Gu, Y., Agbandje-Mckenna, M., Jin, S., Mckenna, R., Wu, D.
Deposit date:2004-01-21
Release date:2004-02-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and mutational characterization of l-carnitine binding to human carnitine acetyltransferase.
J.Struct.Biol., 146, 2004
1T1U
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STRUCTURAL INSIGHTS AND FUNCTIONAL IMPLICATIONS OF CHOLINE ACETYLTRANSFERASE
Descriptor:Choline O-acetyltransferase
Authors:Govindasamy, L., Pedersen, B., Lian, W., Kukar, T., Gu, Y., Jin, S., Agbandje-McKenna, M., Wu, D.
Deposit date:2004-04-18
Release date:2005-04-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural insights and functional implications of choline acetyltransferase
J.Struct.Biol., 148, 2004
2G8G
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STRUCTURALLY MAPPING THE DIVERSE PHENOTYPE OF ADENO-ASSOCIATED VIRUS SEROTYPE 4
Descriptor:Capsid, 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE
Authors:Govindasamy, L., Padron, E., McKenna, R., Muzyczka, N., Chiorini, J.A., Agbandje-McKenna, M.
Deposit date:2006-03-02
Release date:2007-01-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structurally mapping the diverse phenotype of adeno-associated virus serotype 4.
J.Virol., 80, 2006
3KKY
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STRUCTURE OF MANGANESE SUPEROXIDE DISMUTASE FROM DEINOCOCCUS RADIODURANS IN THE ORTHORHOMBIC SPACE GROUP P212121: A CASE STUDY OF MISTAKEN IDENTITY
Descriptor:Superoxide dismutase [Mn], MANGANESE (II) ION
Authors:Govindasamy, L., Mikulski, R., McKenna, M.A., Silverman, D.N., McKenna, R.
Deposit date:2009-11-06
Release date:2010-11-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of Manganese Superoxide dismutase from Deinococcus Radiodurans in the orthorhombic space group P212121: A case study of mistaken identity
To be Published
3NG9
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STRUCTURE TO FUNCTION CORRELATIONS FOR ADENO-ASSOCIATED VIRUS SEROTYPE 1
Descriptor:Capsid protein, ADENINE, 6-AMINOPYRIMIDIN-2(1H)-ONE
Authors:Govindasamy, L., Miller, E.B., Gurda, B., McKenna, R., Zolotukhin, S., Muzyczka, N., Agbandje-McKenna, M.
Deposit date:2010-06-11
Release date:2011-12-21
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure to Function Correlations for Adeno-Associated Virus serotype 1
To be Published
3NTT
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STRUCTURAL INSIGHTS OF ADENO-ASSOCIATED VIRUS 5. A GENE THERAPY VECTOR FOR CYSTIC FIBROSIS
Descriptor:Capsid protein, GLYCEROL, SODIUM ION
Authors:Govindasamy, L., DiMattia, M., Chiorini, J.A., McKenna, R., Muzyczka, N., Agbandje-McKenna, M.
Deposit date:2010-07-05
Release date:2011-12-07
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Structural insights into adeno-associated virus serotype 5.
J.Virol., 87, 2013
1P5W
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THE STRUCTURES OF HOST RANGE CONTROLLING REGIONS OF THE CAPSIDS OF CANINE AND FELINE PARVOVIRUSES AND MUTANTS
Descriptor:5'-D(P*(3DR)P*TP*AP*CP*CP*TP*CP*TP*TP*GP*C)-3', Coat protein VP2, MAGNESIUM ION
Authors:Agbandje-McKenna, M., Govindasamy, L.
Deposit date:2003-04-28
Release date:2003-08-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structures of host range-controlling regions of the capsids of canine and feline parvoviruses and mutants.
J.Virol., 77, 2003
1P5Y
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THE STRUCTURES OF HOST RANGE CONTROLLING REGIONS OF THE CAPSIDS OF CANINE AND FELINE PARVOVIRUSES AND MUTANTS
Descriptor:Coat protein VP2
Authors:Agbandje-McKenna, M., Govindasamy, L.
Deposit date:2003-04-28
Release date:2003-08-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structures of host range-controlling regions of the capsids of canine and feline parvoviruses and mutants.
J.Virol., 77, 2003
3MYU
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MYCOPLASMA GENITALIUM MG289
Descriptor:High affinity transport system protein p37, 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM, ACETATE ION
Authors:Sippel, K.H., Boehlein, S.K., Govindasamy, L., Namiki, K., Satai, Y., Quirit, J.G., Agbandje-McKenna, M., Goodison, S., Rosser, C.J., Sankaran, B., McKenna, R.
Deposit date:2010-05-11
Release date:2010-10-20
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Insights into Mycoplasma genitalium metabolism revealed by the structure of MG289, an extracytoplasmic thiamine binding lipoprotein.
Proteins, 79, 2011
4FIK
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HUMAN CARBONIC ANHYDRASE II H64A COMPLEXED WITH THIOXOLONE HYDROLYSIS PRODUCTS
Descriptor:Carbonic anhydrase 2, ZINC ION, 2,4-dihydroxybenzenesulfenic acid, ...
Authors:Sippel, K.H., Genis, C., Govindasamy, L., Agbandje-McKenna, M., Tripp, B.C., McKenna, R.
Deposit date:2012-06-08
Release date:2012-06-27
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Synchrotron Radiation Provides a Plausible Explanation for the Generation of a Free Radical Adduct of Thioxolone in Mutant Carbonic Anhydrase II.
J Phys Chem Lett, 1, 2010
1LCU
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POLYLYSINE INDUCES AN ANTIPARALLEL ACTIN DIMER THAT NUCLEATES FILAMENT ASSEMBLY: CRYSTAL STRUCTURE AT 3.5 A RESOLUTION
Descriptor:Actin, alpha skeletal muscle, CALCIUM ION, ...
Authors:Bubb, M.R., Govindasamy, L., Yarmola, E.G., Vorobiev, S.M., Almo, S.C., Somasundaram, T., Chapman, M.S., Agbandje-Mckenna, M., Mckenna, R.
Deposit date:2002-04-06
Release date:2002-05-01
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Polylysine induces an antiparallel actin dimer that nucleates filament assembly: crystal structure at 3.5-A resolution.
J.Biol.Chem., 277, 2002
1MOO
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SITE SPECIFIC MUTANT (H64A) OF HUMAN CARBONIC ANHYDRASE II AT HIGH RESOLUTION
Descriptor:Carbonic Anhydrase II, ZINC ION, MERCURY (II) ION, ...
Authors:Duda, D.M., Govindasamy, L., Agbandje-McKenna, M., Tu, C.K., Silverman, D.N., McKenna, R.
Deposit date:2002-09-09
Release date:2002-09-18
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:The refined atomic structure of carbonic anhydrase II at 1.05 A resolution: implications of chemical rescue of proton transfer.
Acta Crystallogr.,Sect.D, 59, 2003
1NM8
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STRUCTURE OF HUMAN CARNITINE ACETYLTRANSFERASE: MOLECULAR BASIS FOR FATTY ACYL TRANSFER
Descriptor:Carnitine O-acetyltransferase
Authors:Wu, D., Govindasamy, L., Lian, W., Gu, Y., Kukar, T., Agbandje-McKenna, M., McKenna, R.
Deposit date:2003-01-09
Release date:2003-03-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of Human Carnitine Acetyltransferase. Molecular Basis for Fatty Acyl Transfer
J.Biol.Chem., 278, 2003
1RDW
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ACTIN CRYSTAL DYNAMICS: STRUCTURAL IMPLICATIONS FOR F-ACTIN NUCLEATION, POLYMERIZATION AND BRANCHING MEDIATED BY THE ANTI-PARALLEL DIMER
Descriptor:Actin, alpha skeletal muscle, MAGNESIUM ION, ...
Authors:Reutzel, R., Yoshioka, C., Govindasamy, L., Yarmola, E.G., Agbandje-Mckenna, M., Bubb, M.R., Mckenna, R.
Deposit date:2003-11-06
Release date:2003-12-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Actin crystal dynamics: structural implications for F-actin nucleation, polymerization, and branching mediated by the anti-parallel dimer.
J.Struct.Biol., 146, 2004
1RFQ
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ACTIN CRYSTAL DYNAMICS: STRUCTURAL IMPLICATIONS FOR F-ACTIN NUCLEATION, POLYMERIZATION AND BRANCHING MEDIATED BY THE ANTI-PARALLEL DIMER
Descriptor:Actin, alpha skeletal muscle, MAGNESIUM ION, ...
Authors:Reutzel, R., Yoshioka, C., Govindasamy, L., Yarmola, E.G., Agbandje-McKenna, M., Bubb, M.R., McKenna, R.
Deposit date:2003-11-10
Release date:2003-12-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Actin crystal dynamics: structural implications for F-actin nucleation, polymerization, and branching mediated by the anti-parallel dimer.
J.Struct.Biol., 146, 2004
1SGU
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COMPARING THE ACCUMULATION OF ACTIVE SITE AND NON-ACTIVE SITE MUTATIONS IN THE HIV-1 PROTEASE
Descriptor:POL polyprotein, N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE
Authors:Clemente, J.C., Moose, R.E., Hemrajani, R., Govindasamy, L., Reutzel, R., Mckenna, R., Abandje-McKenna, M., Goodenow, M.M., Dunn, B.M.
Deposit date:2004-02-24
Release date:2004-10-05
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Comparing the Accumulation of Active- and Nonactive-Site Mutations in the HIV-1 Protease.
Biochemistry, 43, 2004
1SH9
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COMPARING THE ACCUMULATION OF ACTIVE SITE AND NON-ACTIVE SITE MUTATIONS IN THE HIV-1 PROTEASE
Descriptor:POL polyprotein, RITONAVIR
Authors:Clemente, J.C., Moose, R.E., Hemrajani, R., Govindasamy, L., Reutzel, R., McKenna, R., Abanje-McKenna, M., Goodenow, M.M., Dunn, B.M.
Deposit date:2004-02-25
Release date:2004-10-05
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Comparing the Accumulation of Active- and Nonactive-Site Mutations in the HIV-1 Protease.
Biochemistry, 43, 2004
1T9N
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EFFECT OF SHUTTLE LOCATION AND PH ENVIRONMENT ON H+ TRANSFER IN HUMAN CARBONIC ANHYDRASE II
Descriptor:Carbonic anhydrase II, ZINC ION, SULFATE ION
Authors:Fisher, Z., Hernandez Prada, J., Tu, C.K., Duda, D., Yoshioka, C., An, H., Govindasamy, L., Silverman, D.N., McKenna, R.
Deposit date:2004-05-18
Release date:2005-01-25
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and Kinetic Characterization of Active-Site Histidine as a Proton Shuttle in Catalysis by Human Carbonic Anhydrase II
Biochemistry, 44, 2005
1TB0
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EFFECT OF SHUTTLE LOCATION AND PH ENVIRONMENT ON H+ TRANSFER IN HUMAN CARBONIC ANHYDRASE II
Descriptor:Carbonic anhydrase II, ZINC ION, CHLORIDE ION
Authors:Fisher, Z., Hernandez Prada, J.A., Tu, C., Duda, D., Yoshioka, C., An, H., Govindasamy, L., Silverman, D.N., McKenna, R.
Deposit date:2004-05-19
Release date:2005-01-25
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and kinetic characterization of active-site histidine as a proton shuttle in catalysis by human carbonic anhydrase II.
Biochemistry, 44, 2005
1TBT
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EFFECT OF SHUTTLE LOCATION AND PH ENVIRONMENT ON H+ TRANSFER IN HUMAN CARBONIC ANHYDRASE II
Descriptor:Carbonic anhydrase II, ZINC ION
Authors:Fisher, Z., Hernandez Prada, J.A., Tu, C.K., Duda, D., Yoshioka, C., An, H., Govindasamy, L., Silverman, D.N., McKenna, R.
Deposit date:2004-05-20
Release date:2005-01-25
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and Kinetic Characterization of Active-Site Histidine as a Proton Shuttle in Catalysis by Human Carbonic Anhydrase II.
Biochemistry, 44, 2005
1TE3
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EFFECT OF SHUTTLE LOCATION AND PH ENVIRONMENT ON H+ TRANSFER IN HUMAN CARBONIC ANHYDRASE II
Descriptor:Carbonic anhydrase II, ZINC ION, CHLORIDE ION
Authors:Fisher, Z., Hernandez Prada, J.A., Tu, C.K., Duda, D., Yoshioka, C., An, H., Govindasamy, L., Silverman, D.N., McKenna, R.
Deposit date:2004-05-24
Release date:2005-01-25
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and Kinetic Characterization of Active-Site Histidine as a Proton Shuttle in Catalysis by Human Carbonic Anhydrase II
Biochemistry, 44, 2005
1TEQ
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EFFECT OF SHUTTLE LOCATION AND PH ENVIRONMENT ON H+ TRANSFER IN HUMAN CARBONIC ANHYDRASE II
Descriptor:Carbonic anhydrase II, ZINC ION, HYDROXIDE ION
Authors:Fisher, Z., Hernandez Prada, J.A., Tu, C.K., Duda, D., Yoshioka, C., An, H., Govindasamy, L., Silverman, D.N., McKenna, R.
Deposit date:2004-05-25
Release date:2005-01-25
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and Kinetic Characterization of Active-Site Histidine as a Proton Shuttle in Catalysis by Human Carbonic Anhydrase II
Biochemistry, 44, 2005
1TEU
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EFFECT OF SHUTTLE LOCATION AND PH ENVIRONMENT ON H+ TRANSFER IN HUMAN CARBONIC ANHYDRASE II
Descriptor:Carbonic anhydrase II, ZINC ION
Authors:Fisher, Z., Hernandez Prada, J.A., Tu, C.K., Duda, D., Yoshioka, C., An, H., Govindasamy, L., Silverman, D.N., McKenna, R.
Deposit date:2004-05-25
Release date:2005-01-25
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and Kinetic Characterization of Active-Site Histidine as a Proton Shuttle in Catalysis by Human Carbonic Anhydrase II
Biochemistry, 44, 2005
1TG3
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EFFECT OF SHUTTLE LOCATION AND PH ENVIRONMENT ON H+ TRANSFER IN HUMAN CARBONIC ANHYDRASE II
Descriptor:Carbonic anhydrase II, ZINC ION, SULFATE ION
Authors:Fisher, Z., Hernandez Prada, J.A., Tu, C.K., Duda, D., Yoshioka, C., An, H., Govindasamy, L., Silverman, D.N., McKenna, R.
Deposit date:2004-05-28
Release date:2005-01-25
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and Kinetic Characterization of Active-Site Histidine as a Proton Shuttle in Catalysis by Human Carbonic Anhydrase II
Biochemistry, 44, 2005
1TG9
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EFFECT OF SHUTTLE LOCATION AND PH ENVIRONMENT ON H+ TRANSFER IN HUMAN CARBONIC ANHYDRASE II
Descriptor:Carbonic anhydrase II, ZINC ION
Authors:Fisher, Z., Hernandez Prada, J.A., Tu, C.K., Duda, D., Yoshioka, C., An, H., Govindasamy, L., Silverman, D.N., McKenna, R.
Deposit date:2004-05-28
Release date:2005-01-25
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and Kinetic Characterization of Active-Site Histidine as a Proton Shuttle in Catalysis by Human Carbonic Anhydrase II
Biochemistry, 44, 2005
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