Author results

1HT3
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MERCURY INDUCED MODIFICATIONS IN THE STEREOCHEMISTRY OF THE ACTIVE SITE THROUGH CYS-73 IN A SERINE PROTEASE: CRYSTAL STRUCTURE OF THE COMPLEX OF A PARTIALLY MODIFIED PROTEINASE K WITH MERCURY AT 1.8 A RESOLUTION
Descriptor:PROTEINASE K, MERCURY (II) ION, CALCIUM ION
Authors:Gourinath, S.
Deposit date:2000-12-27
Release date:2001-06-27
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mercury induced modifications in the stereochemistry of the active site through Cys-73 in a serine protease--crystal structure of the complex of a partially modified proteinase K with mercury at 1.8 A resolution
Indian J.Biochem.Biophys., 38, 2001
1B1U
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CRYSTAL STRUCTURE OF THE BIFUNCTIONAL INHIBITOR RAGI
Descriptor:PROTEIN (ALPHA-AMYLASE/TRYPSIN INHIBITOR RATI)
Authors:Gourinath, S., Srinivasan, A., Singh, T.P.
Deposit date:1998-11-23
Release date:1998-12-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the bifunctional inhibitor of trypsin and alpha-amylase from ragi seeds at 2.2 A resolution.
Acta Crystallogr.,Sect.D, 56, 2000
1QVI
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CRYSTAL STRUCTURE OF SCALLOP MYOSIN S1 IN THE PRE-POWER STROKE STATE TO 2.6 ANGSTROM RESOLUTION: FLEXIBILITY AND FUNCTION IN THE HEAD
Descriptor:Myosin heavy chain, striated muscle, Myosin regulatory light chain, ...
Authors:Gourinath, S., Himmel, D.M., Brown, J.H., Reshetnikova, L., Szent-Gyrgyi, A.G., Cohen, C.
Deposit date:2003-08-27
Release date:2003-12-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Crystal structure of scallop Myosin s1 in the pre-power stroke state to 2.6 a resolution: flexibility and function in the head.
Structure, 11, 2003
1G0Z
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SPECIFIC MUTATIONS IN KRAIT PLA2 LEAD TO DIMERIZATION OF PROTEIN MOLECULES: CRYSTAL STRUCTURE OF KRAIT PLA2 AT 2.1 RESOLUTION
Descriptor:PHOSPHOLIPASE A2, CHLORIDE ION
Authors:Singh, T.P., Gourinath, S., Sharma, S., Singh, G.
Deposit date:2000-10-10
Release date:2003-06-17
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Specific mutations in Krait PLA2 lead to dimerization of protein molecules: Crystal structure of Krait PLA2 at 2.1 resolution.
To be Published
4LIZ
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CRYSTAL STRUCTURE OF COACTOSIN FROM ENTAMOEBA HISTOLYTICA
Descriptor:Actin-binding protein, cofilin/tropomyosin family protein, putative, ...
Authors:Gourinath, S., Kumar, N.
Deposit date:2013-07-04
Release date:2014-07-23
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.499 Å)
Cite:EhCoactosin stabilizes actin filaments in the protist parasite Entamoeba histolytica.
Plos Pathog., 10, 2014
1G2X
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SEQUENCE INDUCED TRIMERIZATION OF KRAIT PLA2: CRYSTAL STRUCTURE OF THE TRIMERIC FORM OF KRAIT PLA2
Descriptor:PHOSPHOLIPASE A2
Authors:Singh, G., Gourinath, S., Sharma, S., Bhanumathi, S., Paramsivam, M., Singh, T.P.
Deposit date:2000-10-22
Release date:2003-06-17
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Sequence-induced trimerization of phospholipase A2: structure of a trimeric isoform of PLA2 from common krait (Bungarus caeruleus) at 2.5 A resolution.
Acta Crystallogr.,Sect.F, 61, 2005
1S5G
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STRUCTURE OF SCALLOP MYOSIN S1 REVEALS A NOVEL NUCLEOTIDE CONFORMATION
Descriptor:Myosin heavy chain, striated muscle, Myosin regulatory light chain, ...
Authors:Risal, D., Gourinath, S., Himmel, D.M., Szent-Gyorgyi, A.G., Cohen, C.
Deposit date:2004-01-20
Release date:2004-06-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Myosin subfragment 1 structures reveal a partially bound nucleotide and a complex salt bridge that helps couple nucleotide and actin binding.
Proc.Natl.Acad.Sci.Usa, 101, 2004
1SR6
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STRUCTURE OF NUCLEOTIDE-FREE SCALLOP MYOSIN S1
Descriptor:Myosin heavy chain, striated muscle, Myosin regulatory light chain, ...
Authors:Risal, D., Gourinath, S., Himmel, D.M., Szent-Gyorgyi, A.G., Cohen, C.
Deposit date:2004-03-22
Release date:2004-06-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Myosin subfragment 1 structures reveal a partially bound nucleotide and a complex salt bridge that helps couple nucleotide and actin binding.
Proc.Natl.Acad.Sci.Usa, 101, 2004
6AKZ
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CRYSTAL STRUCTURE OF GLCNAC INDUCIBLE GENE 2, GIG2 (DUF1479) FROM CANDIDA ALBICANS
Descriptor:GlcNAc Inducible Gene 2, GIG2, FE (III) ION
Authors:Gautam, G., Rani, P., Dutta, A., Gourinath, S.
Deposit date:2018-09-05
Release date:2019-09-11
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Crystal structure of GlcNAc Inducible Gene2, GIG2 (DUF1479) from Candida albicans at 1.7 Angstroms resolution
To Be Published
5G48
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H.PYLORI BETA CLAMP IN COMPLEX WITH DIFLUNISAL
Descriptor:DNA POLYMERASE III SUBUNIT BETA, 5-(2,4-DIFLUOROPHENYL)-2-HYDROXY-BENZOIC ACID
Authors:Pandey, P., Gourinath, S.
Deposit date:2016-05-06
Release date:2017-06-21
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Targeting the beta-clamp in Helicobacter pylori with FDA-approved drugs reveals micromolar inhibition by diflunisal.
FEBS Lett., 591, 2017
5G4Q
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H.PYLORI BETA CLAMP IN COMPLEX WITH 5-CHLOROISATIN
Descriptor:DNA POLYMERASE III SUBUNIT BETA, 5-chloro-1H-indole-2,3-dione
Authors:Pandey, P., Gourinath, S.
Deposit date:2016-05-16
Release date:2017-06-21
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Screening of E. coli beta-clamp Inhibitors Revealed that Few Inhibit Helicobacter pylori More Effectively: Structural and Functional Characterization.
Antibiotics (Basel), 7, 2018
1U4J
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CRYSTAL STRUCTURE OF A CARBOHYDRATE INDUCED DIMER OF GROUP I PHOSPHOLIPASE A2 FROM BUNGARUS CAERULEUS AT 2.1 A RESOLUTION
Descriptor:phospholipase A2 isoform 2, SODIUM ION, CHLORIDE ION, ...
Authors:Singh, G., Gourinath, S., Sharma, S., Bhanumathi, S., Betzel, C., Srinivasan, A., Singh, T.P.
Deposit date:2004-07-26
Release date:2004-08-10
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Crystal structure of a carbohydrate induced homodimer of phospholipase A(2) from Bungarus caeruleus at 2.1A resolution
J.Struct.Biol., 149, 2005
3BM5
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CRYSTAL STRUCTURE OF O-ACETYL-SERINE SULFHYDRYLASE FROM ENTAMOEBA HISTOLYTICA IN COMPLEX WITH CYSTEINE
Descriptor:Cysteine synthase, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Krishna, C., Kumar, M., Kumar, S., Gourinath, S.
Deposit date:2007-12-12
Release date:2008-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of native O-acetyl-serine sulfhydrylase from Entamoeba histolytica and its complex with cysteine: structural evidence for cysteine binding and lack of interactions with serine acetyl transferase.
Proteins, 72, 2008
3PX1
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STRUCTURE OF CALCIUM BINDING PROTEIN-1 FROM ENTAMOEBA HISTOLYTICA IN COMPLEX WITH STRONTIUM
Descriptor:Calcium-binding protein, STRONTIUM ION
Authors:Kumar, S., Kumar, S., Ahmad, E., Khan, R.H., Gourinath, S.
Deposit date:2010-12-09
Release date:2012-01-25
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Flexibility and plasticity of EF-hand motifs: Structure of Calcium Binding Protein-1 from Entamoeba histolytica in complex with Pb2+, Ba2+, and Sr2+.
To be Published
3ULG
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CRYSTAL STRUCTURE OF CALCIUM-BINDING PROTEIN-1 FROM ENTAMOEBA HISTOLYTICA IN COMPLEX WITH BARIUM
Descriptor:Calcium-binding protein, BARIUM ION
Authors:Kumar, S., Gourinath, S.
Deposit date:2011-11-10
Release date:2012-10-24
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Flexibility of EF-hand motifs: Structural and thermodynamic studies of Calcium Binding Protein- 1 from Entamoeba histolytica with Pb2+, Ba2+, and Sr2+
BMC Biophys, 5, 2012
4HKE
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CRYSTAL STRUCTURE OF MOXT OF BACILLUS ANTHRACIS
Descriptor:Addiction module toxin component PemK, SULFATE ION
Authors:Verma, S., Kumar, S., Gourinath, S., Bhatnagar, R.
Deposit date:2012-10-15
Release date:2013-11-13
Last modified:2014-04-02
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Structural basis of Bacillus anthracis MoxXT disruption and the modulation of MoxT ribonuclease activity by rationally designed peptides
J.Biomol.Struct.Dyn., 2014
4OCI
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CRYSTAL STRUCTURE OF CALCIUM BINDING PROTEIN-5 FROM ENTAMOEBA HISTOLYTICA AND ITS INVOLVEMENT IN INITIATION OF PHAGOCYTOSIS OF HUMAN ERYTHROCYTES
Descriptor:Calmodulin, putative, CALCIUM ION, ...
Authors:Kumar, S., Manjasetty, A.B., Zaidi, R., Gourinath, S.
Deposit date:2014-01-09
Release date:2014-12-24
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.009 Å)
Cite:Crystal Structure of Calcium Binding Protein-5 from Entamoeba histolytica and Its Involvement in Initiation of Phagocytosis of Human Erythrocytes.
Plos Pathog., 10, 2014
5A2H
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CRYSTAL STRUCTURE OF ARABIDOPSIS THALIANA CALMODULIN-7
Descriptor:CALMODULIN, CALCIUM ION, (4S)-2-METHYL-2,4-PENTANEDIOL, ...
Authors:Kumar, S., Gourinath, S.
Deposit date:2015-05-19
Release date:2016-03-30
Last modified:2016-09-28
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Crystal Structure of Arabidopsis Thaliana Calmodulin7 and Insight Into its Mode of DNA Binding.
FEBS Lett., 590, 2016
5YO2
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THE CRYSTAL STRUCTURE OF RV2747 FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH ACETYL COA AND L-ARGININE
Descriptor:Amino-acid acetyltransferase, ARGININE, ACETYL COENZYME *A
Authors:Singh, E., Tiruttani Subhramanyam, U.K., Pal, R.K., Srinivasan, A., Gourinath, S., Das, U.
Deposit date:2017-10-26
Release date:2018-11-07
Last modified:2019-02-13
Method:X-RAY DIFFRACTION (2.997 Å)
Cite:Structural insights into the substrate binding mechanism of novel ArgA from Mycobacterium tuberculosis
Int. J. Biol. Macromol., 125, 2019
6ADD
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THE CRYSTAL STRUCTURE OF RV2747 FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH COA AND NLQ
Descriptor:Amino-acid acetyltransferase, COENZYME A, N~2~-ACETYL-L-GLUTAMINE
Authors:Das, U., Singh, E., Pal, R.K., Tiruttani Subhramanyam, U.K., Gourinath, S., Srinivasan, A.
Deposit date:2018-07-31
Release date:2018-12-26
Last modified:2019-02-13
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Structural insights into the substrate binding mechanism of novel ArgA from Mycobacterium tuberculosis
Int. J. Biol. Macromol., 125, 2019
1DPY
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THREE-DIMENSIONAL STRUCTURE OF A NOVEL PHOSPHOLIPASE A2 FROM INDIAN COMMON KRAIT AT 2.45 A RESOLUTION
Descriptor:PHOSPHOLIPASE A2, SODIUM ION
Authors:Singh, G., Gourinath, S., Sharma, S., Paramasivam, M., Srinivasan, A., Singh, T.P.
Deposit date:1999-12-28
Release date:2000-06-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Sequence and crystal structure determination of a basic phospholipase A2 from common krait (Bungarus caeruleus) at 2.4 A resolution: identification and characterization of its pharmacological sites.
J.Mol.Biol., 307, 2001
1EGQ
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ENHANCEMENT OF ENZYME ACTIVITY THROUGH THREE-PHASE PARTITIONING: CRYSTAL STRUCTURE OF A MODIFIED SERINE PROTEINASE AT 1.5 A RESOLUTION
Descriptor:PROTEINASE K, CALCIUM ION, ACETIC ACID
Authors:Singh, R.K., Gourinath, S., Sharma, S., Ray, I., Gupta, M.N., Singh, T.P.
Deposit date:2000-02-16
Release date:2001-02-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Enhancement of enzyme activity through three-phase partitioning: crystal structure of a modified serine proteinase at 1.5 A resolution.
Protein Eng., 14, 2001
1FE5
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SEQUENCE AND CRYSTAL STRUCTURE OF A BASIC PHOSPHOLIPASE A2 FROM COMMON KRAIT (BUNGARUS CAERULEUS) AT 2.4 RESOLUTION: IDENTIFICATION AND CHARACTERIZATION OF ITS PHARMACOLOGICAL SITES.
Descriptor:PHOSPHOLIPASE A2, CALCIUM ION
Authors:Singh, G., Gourinath, S., Sharma, S., Paramasivam, M., Srinivasan, A., Singh, T.P.
Deposit date:2000-07-21
Release date:2001-01-24
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Sequence and crystal structure determination of a basic phospholipase A2 from common krait (Bungarus caeruleus) at 2.4 A resolution: identification and characterization of its pharmacological sites.
J.Mol.Biol., 307, 2001
1IC6
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STRUCTURE OF A SERINE PROTEASE PROTEINASE K FROM TRITIRACHIUM ALBUM LIMBER AT 0.98 A RESOLUTION
Descriptor:PROTEINASE K, CALCIUM ION, NITRATE ION
Authors:Betzel, C., Gourinath, S., Kumar, P., Kaur, P., Perbandt, M., Eschenburg, S., Singh, T.P.
Deposit date:2001-03-30
Release date:2001-04-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (0.98 Å)
Cite:Structure of a serine protease proteinase K from Tritirachium album limber at 0.98 A resolution.
Biochemistry, 40, 2001
2NXQ
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CRYSTAL STRUCTURE OF CALCIUM BINDING PROTEIN 1 FROM ENTAMOEBA HISTOLYTICA: A NOVEL ARRANGEMENT OF EF HAND MOTIFS
Descriptor:Calcium-binding protein, CALCIUM ION, ACETATE ION
Authors:Kumar, S., Padhan, N., Alam, N., Gourinath, S.
Deposit date:2006-11-18
Release date:2007-08-21
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of calcium binding protein-1 from Entamoeba histolytica: A novel arrangement of EF hand motifs.
Proteins, 68, 2007