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2KBB
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BU of 2kbb by Molmil
Solution Structure of the R9 Domain of Talin
Descriptor: Talin-1
Authors:Goult, B.T, Gingras, A.R, Bate, N, Critchley, D.R, Barsukov, I.L.
Deposit date:2008-11-24
Release date:2009-03-17
Last modified:2021-08-25
Method:SOLUTION NMR
Cite:The structure of an interdomain complex that regulates talin activity.
J.Biol.Chem., 284, 2009
2KC2
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BU of 2kc2 by Molmil
NMR structure of the F1 domain (residues 86-202) of the talin
Descriptor: Talin-1
Authors:Goult, B.T, Elliott, P.R, Roberts, G.C.K, Critchely, D.R, Barsukov, I.L.
Deposit date:2008-12-13
Release date:2010-01-19
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation.
Embo J., 29, 2010
2KGX
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BU of 2kgx by Molmil
HADDOCK structure of the talin F3 domain in complex with talin 1655-1822
Descriptor: MKIAA1027 protein, Talin-1
Authors:Goult, B.T, Gingras, A.R, Bate, N, Critchley, D.R, Barsukov, I.L.
Deposit date:2009-03-23
Release date:2009-03-31
Last modified:2021-10-20
Method:SOLUTION NMR
Cite:The structure of an interdomain complex that regulates talin activity.
J.Biol.Chem., 284, 2009
2KMC
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BU of 2kmc by Molmil
Solution Structure of the N-terminal domain of kindlin-1
Descriptor: Fermitin family homolog 1
Authors:Goult, B.T, Bate, N, Roberts, G.C, Barsukov, I.L, Critchley, D.R.
Deposit date:2009-07-27
Release date:2009-10-06
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:The Structure of the N-Terminus of Kindlin-1: A Domain Important for alphaIIbbeta3 Integrin Activation
J.Mol.Biol., 394, 2009
2KC1
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BU of 2kc1 by Molmil
NMR structure of the F0 domain (residues 0-85) of the talin ferm domain
Descriptor: MKIAA1027 protein
Authors:Goult, B.T, Elliott, P.R, Roberts, G.C.K, Critchley, D.R, Barsukov, I.L.
Deposit date:2008-12-13
Release date:2010-01-19
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation.
Embo J., 29, 2010
2KMA
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BU of 2kma by Molmil
NMR structure of the F0F1 double domain (residues 1-202) of the talin ferm domain
Descriptor: Talin 1
Authors:Goult, B.T, Elliott, P.R, Bate, N, Roberts, G.C, Critchley, D.R, Barsukov, I.L.
Deposit date:2009-07-25
Release date:2010-03-02
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation.
Embo J., 2010
2KVP
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BU of 2kvp by Molmil
Solution Structure of the R10 Domain of Talin
Descriptor: Talin-1
Authors:Goult, B.T, Gingras, A.R, Bate, N, Critchley, D.R, Barsukov, I.L, Roberts, G.C.
Deposit date:2010-03-24
Release date:2010-05-05
Last modified:2021-08-25
Method:SOLUTION NMR
Cite:The domain structure of talin: Residues 1815-1973 form a five-helix bundle containing a cryptic vinculin-binding site.
Febs Lett., 584, 2010
2L7N
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BU of 2l7n by Molmil
Solution Structure of the R5 Domain of Talin
Descriptor: Talin-1
Authors:Goult, B.T, Gingras, A.R, Bate, N, Barsukov, I.L, Roberts, G.C.K, Critchley, D.R.
Deposit date:2010-12-14
Release date:2011-12-14
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover.
J.Biol.Chem., 288, 2013
2L7A
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BU of 2l7a by Molmil
Solution Structure of the R3 Domain of Talin
Descriptor: Talin-1
Authors:Goult, B.T, Gingras, A.R, Bate, N, Roberts, G.C.K, Barsukov, I.L, Critchley, D.R.
Deposit date:2010-12-06
Release date:2011-12-21
Last modified:2021-08-25
Method:SOLUTION NMR
Cite:RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover.
J.Biol.Chem., 288, 2013
2L10
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BU of 2l10 by Molmil
Solution Structure of the R6 Domain of Talin
Descriptor: Talin-1
Authors:Goult, B.T, Gingras, A.R, Bate, N, Roberts, G.C.K, Barsukov, I.L, Critchley, D.R.
Deposit date:2010-07-22
Release date:2011-08-31
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover.
J.Biol.Chem., 288, 2013
2LQG
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BU of 2lqg by Molmil
Solution Structure of the R4 domain of talin
Descriptor: Talin-1
Authors:Goult, B.T, Gingras, A.R, Bate, N, Roberts, G.C.K, Barsukov, I.L, Critchley, D.R.
Deposit date:2012-03-06
Release date:2013-02-13
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:RIAM and Vinculin Binding to Talin Are Mutually Exclusive and Regulate Adhesion Assembly and Turnover.
J.Biol.Chem., 288, 2013
2JSW
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BU of 2jsw by Molmil
Solution Structure of the R13 Domain of Talin
Descriptor: Talin-1
Authors:Goult, B.T, Gingras, A.R, Bate, N, Critchley, D.R.C, Barsukov, I.L.
Deposit date:2007-07-17
Release date:2008-01-29
Last modified:2021-08-25
Method:SOLUTION NMR
Cite:The structure of the C-terminal actin-binding domain of talin.
Embo J., 27, 2007
3ZDL
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BU of 3zdl by Molmil
Vinculin head (1-258) in complex with a RIAM fragment
Descriptor: AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B MEMBER 1-INTERACTING PROTEIN, VINCULIN
Authors:Zacharchenko, T, Elliott, P.R, Goult, B.T, Bate, N, Critchely, D.R, Barsukov, I.L.
Deposit date:2012-11-28
Release date:2013-02-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Riam and Vinculin Binding to Talin are Mutually Exclusive and Regulate Adhesion Assembly and Turnover.
J.Biol.Chem., 288, 2013
5OEO
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BU of 5oeo by Molmil
Solution structure of the complex of TRPV5(655-725) with a Calmodulin E32Q/E68Q double mutant
Descriptor: CALCIUM ION, Calmodulin-1, Transient receptor potential cation channel subfamily V member 5
Authors:Vuister, G.W, Bokhovchuk, F.M, Bate, N, Kovalevskaya, N, Goult, B.T, Spronk, C.A.E.M.
Deposit date:2017-07-09
Release date:2018-04-25
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:The Structural Basis of Calcium-Dependent Inactivation of the Transient Receptor Potential Vanilloid 5 Channel.
Biochemistry, 57, 2018
5FZT
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BU of 5fzt by Molmil
The crystal structure of R7R8 in complex with a DLC1 fragment.
Descriptor: MALONATE ION, RHO GTPASE-ACTIVATING PROTEIN 7, TALIN-1
Authors:Zacharchenko, T, Qian, X, Goult, B.T, Jethwa, D, Almeida, T, Ballestrem, C, Critchley, D.R, Lowy, D.R, Barsukov, I.L.
Deposit date:2016-03-15
Release date:2016-04-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Ld Motif Recognition by Talin: Structure of the Talin-Dlc1 Complex.
Structure, 24, 2016
6XZ4
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BU of 6xz4 by Molmil
Crystal structure of TLNRD1
Descriptor: Talin rod domain-containing protein 1
Authors:Cowell, A, Singh, A.K, Brown, D.G, Goult, B.T.
Deposit date:2020-02-01
Release date:2020-05-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Talin rod domain-containing protein 1 (TLNRD1) is a novel actin-bundling protein which promotes filopodia formation.
J.Cell Biol., 220, 2021
6XZ3
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BU of 6xz3 by Molmil
Crystal structure of TLNRD1 4-helix bundle
Descriptor: 1,2-ETHANEDIOL, Talin rod domain-containing protein 1
Authors:Cowell, A, Singh, A.K, Brown, D.G, Goult, B.T.
Deposit date:2020-02-01
Release date:2020-05-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Talin rod domain-containing protein 1 (TLNRD1) is a novel actin-bundling protein which promotes filopodia formation.
J.Cell Biol., 220, 2021
3IVF
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BU of 3ivf by Molmil
Crystal structure of the talin head FERM domain
Descriptor: Talin-1
Authors:Elliott, P.R, Goult, B.T, Bate, N, Grossmann, J.G, Roberts, G.C.K, Critchley, D.R, Barsukov, I.L.
Deposit date:2009-09-01
Release date:2010-08-18
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:The Structure of the talin head reveals a novel extended conformation of the FERM domain
Structure, 18, 2010
6TWN
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BU of 6twn by Molmil
Crystal structure of Talin1 R7R8 in complex with CDK1 (206-223)
Descriptor: CHLORIDE ION, Cyclin-dependent kinase 1, GLYCEROL, ...
Authors:Zacharchenko, T, Muench, S.P, Goult, B.T.
Deposit date:2020-01-13
Release date:2021-05-12
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Talin mechanosensitivity is modulated by a direct interaction with cyclin-dependent kinase-1.
J.Biol.Chem., 297, 2021
6FQ4
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BU of 6fq4 by Molmil
Structure of Chlamydial virulence factor TarP and vinculin head domain
Descriptor: TarP-VBS1, Vinculin
Authors:Whitewood, A.J, Singh, A.K, Brown, D.G, Goult, B.T.
Deposit date:2018-02-13
Release date:2018-05-09
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Chlamydial virulence factor TarP mimics talin to disrupt the talin-vinculin complex.
FEBS Lett., 592, 2018
2IVW
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BU of 2ivw by Molmil
The solution structure of a domain from the Neisseria meningitidis PilP pilot protein.
Descriptor: PILP PILOT PROTEIN
Authors:Golovanov, A.P, Balasingham, S, Tzitzilonis, C, Goult, B.T, Lian, L.-Y, Homberset, H, Tonjum, T, Derrick, J.P.
Deposit date:2006-06-20
Release date:2007-02-13
Last modified:2018-05-09
Method:SOLUTION NMR
Cite:The solution structure of a domain from the Neisseria meningitidis lipoprotein PilP reveals a new beta-sandwich fold.
J. Mol. Biol., 364, 2006
6TLH
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BU of 6tlh by Molmil
Crystal structure of mouse KANK3 ankyrin repeats
Descriptor: FORMIC ACID, GLYCEROL, KN motif and ankyrin repeat domain-containing protein 3
Authors:Khan, R, Singh, A.K, Goult, B.T.
Deposit date:2019-12-02
Release date:2020-12-16
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of mouse KANK3 ankyrin repeats
To be published
6TMD
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BU of 6tmd by Molmil
Crystal structure of KANK2 ankyrin repeats mutant (A670V)
Descriptor: ACETATE ION, GLYCEROL, KN motif and ankyrin repeat domain-containing protein 2
Authors:Khan, R, Singh, A.K, Goult, B.T.
Deposit date:2019-12-04
Release date:2020-12-16
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of KANK2 ankyrin repeats mutant (A670V)
To be published
2YHN
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BU of 2yhn by Molmil
The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor
Descriptor: E3 UBIQUITIN-PROTEIN LIGASE MYLIP, ZINC ION
Authors:Fairall, L, Goult, B.T, Millard, C.J, Tontonoz, P, Schwabe, J.W.R.
Deposit date:2011-05-04
Release date:2011-06-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Idol-Ube2D Complex Mediates Sterol-Dependent Degradation of the Ldl Receptor.
Genes Dev., 25, 2011
4CP3
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BU of 4cp3 by Molmil
The structure of BCL6 BTB (POZ) domain in complex with the ansamycin antibiotic rifabutin.
Descriptor: B-CELL LYMPHOMA 6 PROTEIN, RIFABUTIN
Authors:Evans, S.E, Fairall, L, Goult, B.T, Jamieson, A.G, Ferrigno, P.K, Ford, R, Wagner, S.D, Schwabe, J.W.R.
Deposit date:2014-01-31
Release date:2014-03-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Ansamycin Antibiotic, Rifamycin Sv, Inhibits Bcl6 Transcriptional Repression and Forms a Complex with the Bcl6-Btb/Poz Domain.
Plos One, 9, 2014

 

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