Author results

2KBB
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NMR STRUCTURE OF THE TALIN ROD DOMAIN, 1655-1822
Descriptor:Talin-1
Authors:Goult, B.T., Gingras, A.R., Bate, N., Critchley, D.R., Barsukov, I.L.
Deposit date:2008-11-24
Release date:2009-03-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The structure of an interdomain complex that regulates talin activity.
J.Biol.Chem., 284, 2009
2KC1
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NMR STRUCTURE OF THE F0 DOMAIN (RESIDUES 0-85) OF THE TALIN FERM DOMAIN
Descriptor:MKIAA1027 protein
Authors:Goult, B.T., Elliott, P.R., Roberts, G.C.K., Critchley, D.R., Barsukov, I.L.
Deposit date:2008-12-13
Release date:2010-01-19
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation.
Embo J., 29, 2010
2KC2
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NMR STRUCTURE OF THE F1 DOMAIN (RESIDUES 86-202) OF THE TALIN
Descriptor:Talin-1
Authors:Goult, B.T., Elliott, P.R., Roberts, G.C.K., Critchely, D.R., Barsukov, I.L.
Deposit date:2008-12-13
Release date:2010-01-19
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation.
Embo J., 29, 2010
2KGX
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HADDOCK STRUCTURE OF THE TALIN F3 DOMAIN IN COMPLEX WITH TALIN 1655-1822
Descriptor:Talin-1, MKIAA1027 protein
Authors:Goult, B.T., Gingras, A.R., Bate, N., Critchley, D.R., Barsukov, I.L.
Deposit date:2009-03-23
Release date:2009-03-31
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The structure of an interdomain complex that regulates talin activity.
J.Biol.Chem., 284, 2009
2KMA
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NMR STRUCTURE OF THE F0F1 DOUBLE DOMAIN (RESIDUES 1-202) OF THE TALIN FERM DOMAIN
Descriptor:Talin 1
Authors:Goult, B.T., Elliott, P.R., Bate, N., Roberts, G.C., Critchley, D.R., Barsukov, I.L.
Deposit date:2009-07-25
Release date:2010-03-02
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation.
Embo J., 2010
2KMC
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SOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF KINDLIN-1
Descriptor:Fermitin family homolog 1
Authors:Goult, B.T., Bate, N., Roberts, G.C., Barsukov, I.L., Critchley, D.R.
Deposit date:2009-07-27
Release date:2009-10-06
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The Structure of the N-Terminus of Kindlin-1: A Domain Important for alphaIIbbeta3 Integrin Activation
J.Mol.Biol., 394, 2009
2KVP
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NMR STRUCTURE OF THE TALIN VBS3 DOMAIN, 1815-1973
Descriptor:Talin-1
Authors:Goult, B.T., Gingras, A.R., Bate, N., Critchley, D.R., Barsukov, I.L., Roberts, G.C.
Deposit date:2010-03-24
Release date:2010-05-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The domain structure of talin: Residues 1815-1973 form a five-helix bundle containing a cryptic vinculin-binding site.
Febs Lett., 584, 2010
2L10
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STRUCTURE OF THE TALIN ROD RESIDUES, DOMAIN C
Descriptor:Talin-1
Authors:Goult, B.T., Gingras, A.R., Bate, N., Roberts, G.C.K., Barsukov, I.L., Critchley, D.R.
Deposit date:2010-07-22
Release date:2011-08-31
Last modified:2014-01-15
Method:SOLUTION NMR
Cite:RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover.
J.Biol.Chem., 288, 2013
2L7A
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SOLUTION STRUCTURE OF THE TALIN VBS2B DOMAIN
Descriptor:Talin-1
Authors:Goult, B.T., Gingras, A.R., Bate, N., Roberts, G.C.K., Barsukov, I.L., Critchley, D.R.
Deposit date:2010-12-06
Release date:2011-12-21
Last modified:2014-01-15
Method:SOLUTION NMR
Cite:RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover.
J.Biol.Chem., 288, 2013
2L7N
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NMR STRUCTURE OF THE B DOMAIN OF TALIN
Descriptor:Talin-1
Authors:Goult, B.T., Gingras, A.R., Bate, N., Barsukov, I.L., Roberts, G.C.K., Critchley, D.R.
Deposit date:2010-12-14
Release date:2011-12-14
Last modified:2014-01-15
Method:SOLUTION NMR
Cite:RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover.
J.Biol.Chem., 288, 2013
2LQG
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SOLUTION STRUCTURE OF THE R4 DOMAIN OF TALIN
Descriptor:Talin-1
Authors:Goult, B.T., Gingras, A.R., Bate, N., Roberts, G.C.K., Barsukov, I.L., Critchley, D.R.
Deposit date:2012-03-06
Release date:2013-02-13
Last modified:2013-04-24
Method:SOLUTION NMR
Cite:RIAM and Vinculin Binding to Talin Are Mutually Exclusive and Regulate Adhesion Assembly and Turnover.
J.Biol.Chem., 288, 2013
2JSW
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NMR STRUCTURE OF THE TALIN C-TERMINAL ACTIN BINDING SITE
Descriptor:Talin-1
Authors:Goult, B.T., Gingras, A.R., Bate, N., Critchley, D.R.C., Barsukov, I.L.
Deposit date:2007-07-17
Release date:2008-01-29
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The structure of the C-terminal actin-binding domain of talin.
Embo J., 27, 2007
3ZDL
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VINCULIN HEAD (1-258) IN COMPLEX WITH A RIAM FRAGMENT
Descriptor:VINCULIN, AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B MEMBER 1-INTERACTING PROTEIN
Authors:Zacharchenko, T., Elliott, P.R., Goult, B.T., Bate, N., Critchely, D.R., Barsukov, I.L.
Deposit date:2012-11-28
Release date:2013-02-13
Last modified:2013-04-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Riam and Vinculin Binding to Talin are Mutually Exclusive and Regulate Adhesion Assembly and Turnover.
J.Biol.Chem., 288, 2013
2IVW
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THE SOLUTION STRUCTURE OF A DOMAIN FROM THE NEISSERIA MENINGITIDIS PILP PILOT PROTEIN.
Descriptor:PILP PILOT PROTEIN
Authors:Golovanov, A.P., Balasingham, S., Tzitzilonis, C., Goult, B.T., Lian, L.-Y., Homberset, H., Tonjum, T., Derrick, J.P.
Deposit date:2006-06-20
Release date:2007-02-13
Last modified:2018-05-09
Method:SOLUTION NMR
Cite:The solution structure of a domain from the Neisseria meningitidis lipoprotein PilP reveals a new beta-sandwich fold.
J. Mol. Biol., 364, 2006
2KN4
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THE STRUCTURE OF THE RRM DOMAIN OF SC35
Descriptor:Immunoglobulin G-binding protein G, Splicing factor; arginine/serine-rich 2
Authors:Clayton, J.C., Goult, B.T., Lian, L.-Y.
Deposit date:2009-08-14
Release date:2010-08-18
Last modified:2011-12-21
Method:SOLUTION NMR
Cite:The structure and selectivity of the SR protein SRSF2 RRM domain with RNA
Nucleic Acids Res., 2011
2X0C
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STRUCTURE OF THE TALIN ROD RESIDUES 1359-1659
Descriptor:TALIN-1
Authors:Gingras, A.R., Goult, B.T., Bate, N., Barsukov, I.L., Emsley, J., Critchely, D.R.
Deposit date:2009-12-08
Release date:2010-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Central Region of Talin Has a Unique Fold that Binds Vinculin and Actin.
J.Biol.Chem., 285, 2010
2YHN
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THE IDOL-UBE2D COMPLEX MEDIATES STEROL-DEPENDENT DEGRADATION OF THE LDL RECEPTOR
Descriptor:E3 UBIQUITIN-PROTEIN LIGASE MYLIP, ZINC ION
Authors:Fairall, L., Goult, B.T., Millard, C.J., Tontonoz, P., Schwabe, J.W.R.
Deposit date:2011-05-04
Release date:2011-06-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Idol-Ube2D Complex Mediates Sterol-Dependent Degradation of the Ldl Receptor.
Genes Dev., 25, 2011
2YHO
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THE IDOL-UBE2D COMPLEX MEDIATES STEROL-DEPENDENT DEGRADATION OF THE LDL RECEPTOR
Descriptor:E3 UBIQUITIN-PROTEIN LIGASE MYLIP, UBIQUITIN-CONJUGATING ENZYME E2 D1, ZINC ION, ...
Authors:Fairall, L., Goult, B.T., Millard, C.J., Tontonoz, P., Schwabe, J.W.R.
Deposit date:2011-05-04
Release date:2011-06-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Idol-Ube2D Complex Mediates Sterol-Dependent Degradation of the Ldl Receptor.
Genes Dev., 25, 2011
3IVF
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CRYSTAL STRUCTURE OF THE TALIN HEAD FERM DOMAIN
Descriptor:Talin-1
Authors:Elliott, P.R., Goult, B.T., Bate, N., Grossmann, J.G., Roberts, G.C.K., Critchley, D.R., Barsukov, I.L.
Deposit date:2009-09-01
Release date:2010-08-18
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:The Structure of the talin head reveals a novel extended conformation of the FERM domain
Structure, 18, 2010
4CP3
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THE STRUCTURE OF BCL6 BTB (POZ) DOMAIN IN COMPLEX WITH THE ANSAMYCIN ANTIBIOTIC RIFABUTIN.
Descriptor:B-CELL LYMPHOMA 6 PROTEIN, RIFABUTIN
Authors:Evans, S.E., Fairall, L., Goult, B.T., Jamieson, A.G., Ferrigno, P.K., Ford, R., Wagner, S.D., Schwabe, J.W.R.
Deposit date:2014-01-31
Release date:2014-03-19
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Ansamycin Antibiotic, Rifamycin Sv, Inhibits Bcl6 Transcriptional Repression and Forms a Complex with the Bcl6-Btb/Poz Domain.
Plos One, 9, 2014
5FZT
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THE CRYSTAL STRUCTURE OF R7R8 IN COMPLEX WITH A DLC1 FRAGMENT.
Descriptor:TALIN-1, RHO GTPASE-ACTIVATING PROTEIN 7, MALONATE ION
Authors:Zacharchenko, T., Qian, X., Goult, B.T., Jethwa, D., Almeida, T., Ballestrem, C., Critchley, D.R., Lowy, D.R., Barsukov, I.L.
Deposit date:2016-03-15
Release date:2016-04-27
Last modified:2016-07-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Ld Motif Recognition by Talin: Structure of the Talin-Dlc1 Complex.
Structure, 24, 2016
5OEO
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SOLUTION STRUCTURE OF THE COMPLEX OF TRPV5(655-725) WITH A CALMODULIN E32Q/E68Q DOUBLE MUTANT
Descriptor:Calmodulin-1, Transient receptor potential cation channel subfamily V member 5, CALCIUM ION
Authors:Vuister, G.W., Bokhovchuk, F.M., Bate, N., Kovalevskaya, N., Goult, B.T., Spronk, C.A.E.M.
Deposit date:2017-07-09
Release date:2018-04-25
Last modified:2018-05-16
Method:SOLUTION NMR
Cite:The Structural Basis of Calcium-Dependent Inactivation of the Transient Receptor Potential Vanilloid 5 Channel.
Biochemistry, 57, 2018
6FQ4
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STRUCTURE OF CHLAMYDIAL VIRULENCE FACTOR TARP AND VINCULIN HEAD DOMAIN
Descriptor:Vinculin, TarP-VBS1
Authors:Whitewood, A.J., Singh, A.K., Brown, D.G., Goult, B.T.
Deposit date:2018-02-13
Release date:2018-05-09
Last modified:2018-06-13
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Chlamydial virulence factor TarP mimics talin to disrupt the talin-vinculin complex.
FEBS Lett., 592, 2018
2L5G
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CO-ORDINATES AND 1H, 13C AND 15N CHEMICAL SHIFT ASSIGNMENTS FOR THE COMPLEX OF GPS2 53-90 AND SMRT 167-207
Descriptor:G protein pathway suppressor 2, Putative uncharacterized protein NCOR2
Authors:Oberoi, J., Yang, J., Neuhaus, D., Schwabe, J.W.R.
Deposit date:2010-11-01
Release date:2011-02-02
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery.
Nat.Struct.Mol.Biol., 18, 2011
2QDQ
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CRYSTAL STRUCTURE OF THE TALIN DIMERISATION DOMAIN
Descriptor:Talin-1
Authors:Gingras, A.R., Putz, N.S.M., Bate, N., Barsukov, I.L., Critchley, D.R.C.
Deposit date:2007-06-21
Release date:2008-01-29
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure of the C-terminal actin-binding domain of talin.
Embo J., 27, 2008
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