Author results

5ESV
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CRYSTAL STRUCTURE OF BROADLY NEUTRALIZING ANTIBODY CH03, ISOLATED FROM DONOR CH0219, IN COMPLEX WITH SCAFFOLDED TRIMERIC HIV-1 ENV V1V2 DOMAIN FROM THE CLADE C SUPERINFECTING STRAIN OF DONOR CAP256.
Descriptor:CH03 Heavy Chain, CH03 Light Chain, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase,Envelope glycoprotein gp160, ...
Authors:Gorman, J., Yang, M., Kwong, P.D.
Deposit date:2015-11-17
Release date:2015-12-16
Last modified:2016-01-13
Method:X-RAY DIFFRACTION (3.105 Å)
Cite:Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design.
Nat.Struct.Mol.Biol., 23, 2016
5ESZ
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CRYSTAL STRUCTURE OF BROADLY NEUTRALIZING ANTIBODY CH04, ISOLATED FROM DONOR CH0219, IN COMPLEX WITH SCAFFOLDED TRIMERIC HIV-1 ENV V1V2 DOMAIN FROM THE CLADE AE STRAIN A244
Descriptor:CH04 Heavy Chain, CH04 Light Chain, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase,Envelope glycoprotein gp160, ...
Authors:Gorman, J., Yang, M., Kwong, P.D.
Deposit date:2015-11-17
Release date:2015-12-16
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (4.191 Å)
Cite:Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design.
Nat. Struct. Mol. Biol., 23, 2016
1R3D
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CRYSTAL STRUCTURE OF PROTEIN VC1974 FROM VIBRIO CHOLERAE, PFAM ABHYDROLASE
Descriptor:conserved hypothetical protein VC1974
Authors:Gorman, J., Shapiro, L., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2003-10-01
Release date:2004-11-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Genomics target NYSGRC-T920 related to A/B hydrolase fold.
To be Published
1S80
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STRUCTURE OF SERINE ACETYLTRANSFERASE FROM HAEMOPHILIS INFLUENZAE RD
Descriptor:Serine acetyltransferase
Authors:Gorman, J., Gogos, A., Shapiro, L., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2004-01-30
Release date:2004-08-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of serine acetyltransferase from Haemophilus influenzae Rd.
Acta Crystallogr.,Sect.D, 60, 2004
1TO3
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STRUCTURE OF YIHT FROM SALMONELLA TYPHIMURIUM
Descriptor:Putative aldolase yihT, PHOSPHATE ION, BROMIDE ION
Authors:Gorman, J., Shapiro, L., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2004-06-11
Release date:2004-06-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of yiht from Salmonella typhimurium
To be Published
1TR9
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STRUCTURE OF BETA-HEXOSAMINIDASE FROM VIBRIO CHOLERAE
Descriptor:Beta-hexosaminidase
Authors:Gorman, J., Shapiro, L., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2004-06-21
Release date:2004-12-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of beta-hexosaminidase from Vibrio cholerae
To be Published
1TVL
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STRUCTURE OF YTNJ FROM BACILLUS SUBTILIS
Descriptor:protein YTNJ
Authors:Gorman, J., Shapiro, L., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2004-06-29
Release date:2004-07-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.104 Å)
Cite:Structure of YTNJ from Bacillus subtilis
To be Published
1Y65
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CRYSTAL STRUCTURE OF BETA-HEXOSAMINIDASE FROM VIBRIO CHOLERAE IN COMPLEX WITH N-ACETYL-D-GLUCOSAMINE TO A RESOLUTION OF 1.85
Descriptor:Beta-hexosaminidase, N-ACETYL-D-GLUCOSAMINE
Authors:Gorman, J., Shapiro, L., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2004-12-03
Release date:2004-12-14
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of beta-hexosaminidase from Vibrio cholerae in complex with N-acetyl-D-glucosamine to a resolution of 1.85
To be Published
1YDG
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CRYSTAL STRUCTURE OF TRP REPRESSOR BINDING PROTEIN WRBA
Descriptor:trp repressor binding protein WrbA, SULFATE ION
Authors:Gorman, J., Shapiro, L., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2004-12-23
Release date:2005-01-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of the tryptophan repressor binding protein WrbA and complexes with flavin mononucleotide.
Protein Sci., 14, 2005
1YRH
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CRYSTAL STRUCTURE OF TRP REPRESSOR BINDING PROTEIN WRBA IN COMPLEX WITH FMN
Descriptor:trp repressor binding protein WrbA, FLAVIN MONONUCLEOTIDE
Authors:Gorman, J., Shapiro, L., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2005-02-03
Release date:2005-02-15
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Crystal structures of the tryptophan repressor binding protein WrbA and complexes with flavin mononucleotide.
Protein Sci., 14, 2005
1ZWK
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STRUCTURE OF WRBA FROM PSEUDOMONAS AERUGINOSA
Descriptor:Trp repressor binding protein WrbA, PHOSPHATE ION
Authors:Gorman, J., Shapiro, L., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2005-06-03
Release date:2005-06-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of the tryptophan repressor binding protein WrbA and complexes with flavin mononucleotide.
Protein Sci., 14, 2005
1ZWL
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STRUCTURE OF WRBA FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH FMN
Descriptor:Trp repressor binding protein WrbA, FLAVIN MONONUCLEOTIDE
Authors:Gorman, J., Shapiro, L., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2005-06-03
Release date:2005-06-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of the tryptophan repressor binding protein WrbA and complexes with flavin mononucleotide.
Protein Sci., 14, 2005
2A1F
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CRYSTAL STRUCTURE OF URIDYLATE KINASE
Descriptor:Uridylate kinase
Authors:Gorman, J., Shapiro, L., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2005-06-20
Release date:2005-06-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of Uridylate kinase
To be Published
2AKO
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CRYSTAL STRUCTURE OF GLUTAMATE 5-KINASE FROM CAMPYLOBACTER JEJUNI
Descriptor:Glutamate 5-kinase, ADENOSINE-5'-DIPHOSPHATE
Authors:Gorman, J., Shapiro, L., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2005-08-03
Release date:2005-08-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of Glutamate 5-kinase from Campylobacter jejuni
To be Published
2AWD
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CRYSTAL STRUCTURE OF LACC FROM ENTEROCOCCUS FAECALIS
Descriptor:tagatose-6-phosphate kinase, BROMIDE ION
Authors:Gorman, J., Shapiro, L., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2005-08-31
Release date:2005-09-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of LacC from Enterococcus faecalis
To be Published
2F02
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CRYSTAL STRUCTURE OF LACC FROM ENTEROCOCCUS FAECALIS IN COMPLEX WITH ATP
Descriptor:tagatose-6-phosphate kinase, ADENOSINE-5'-TRIPHOSPHATE
Authors:Gorman, J., Shapiro, L., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2005-11-10
Release date:2005-11-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of LacC from Enterococcus Faecalis in complex with ATP
To be Published
3U4E
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CRYSTAL STRUCTURE OF PG9 FAB IN COMPLEX WITH V1V2 REGION FROM HIV-1 STRAIN CAP45
Descriptor:V1V2 region of HIV-1 on 1FD6 scaffold, PG9 Heavy Chain, PG9 Light Chain, ...
Authors:Gorman, J., McLellan, J., Pancera, M., Kwong, P.D.
Deposit date:2011-10-07
Release date:2011-11-30
Last modified:2011-12-21
Method:X-RAY DIFFRACTION (2.185 Å)
Cite:Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
5EWI
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CRYSTAL STRUCTURE OF THE HUMAN FAB VRC38.01, AN HIV-1 V1V2-DIRECTED NEUTRALIZING ANTIBODY ISOLATED FROM DONOR N90
Descriptor:VRC38.01 Heavy Chain, VRC38.01 Light Chain
Authors:Gorman, J., Kwong, P.D.
Deposit date:2015-11-20
Release date:2016-11-23
Last modified:2017-05-31
Method:X-RAY DIFFRACTION (1.5996 Å)
Cite:Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop.
Immunity, 46, 2017
5VGJ
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CRYSTAL STRUCTURE OF THE HUMAN FAB VRC38.01, AN HIV-1 V1V2-DIRECTED NEUTRALIZING ANTIBODY ISOLATED FROM DONOR N90, BOUND TO A SCAFFOLDED WITO V1V2 DOMAIN
Descriptor:1FD6-V1V2-WITO, VRC38.01 Fab Heavy Chain, VRC38.01 Fab Light Chain, ...
Authors:Gorman, J., Li, J., Kwong, P.D.
Deposit date:2017-04-11
Release date:2017-05-31
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.456 Å)
Cite:Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop.
Immunity, 46, 2017
4OCR
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CRYSTAL STRUCTURE OF HUMAN FAB CAP256-VRC26.01, A POTENT V1V2-DIRECTED HIV-1 NEUTRALIZING ANTIBODY
Descriptor:CAP256-VRC26.01 light chain, CAP256-VRC26.01 heavy chain
Authors:Gorman, J., Doria-Rose, N.A., Schramm, C.A., Moore, P.L., Mascola, J.R., Shapiro, L., Morris, L., Kwong, P.D.
Deposit date:2014-01-09
Release date:2014-02-26
Last modified:2014-05-14
Method:X-RAY DIFFRACTION (1.895 Å)
Cite:Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies.
Nature, 509, 2014
4OCS
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CRYSTAL STRUCTURE OF HUMAN FAB CAP256-VRC26.10, A POTENT V1V2-DIRECTED HIV-1 NEUTRALIZING ANTIBODY
Descriptor:CAP256-VRC26.10 light chain, CAP256-VRC26.10 heavy chain
Authors:Gorman, J., Doria-Rose, N.A., Schramm, C.A., Moore, P.L., Mascola, J.R., Shapiro, L., Morris, L., Kwong, P.D.
Deposit date:2014-01-09
Release date:2014-02-26
Last modified:2014-05-14
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies.
Nature, 509, 2014
4OCW
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CRYSTAL STRUCTURE OF HUMAN FAB CAP256-VRC26.06, A POTENT V1V2-DIRECTED HIV-1 NEUTRALIZING ANTIBODY
Descriptor:CAP256-VRC26.06 light chain, CAP256-VRC26.06 heavy chain
Authors:Gorman, J., Doria-Rose, N.A., Schramm, C.A., Moore, P.L., Mascola, J.R., Shapiro, L., Morris, L., Kwong, P.D.
Deposit date:2014-01-09
Release date:2014-02-26
Last modified:2014-05-14
Method:X-RAY DIFFRACTION (3.001 Å)
Cite:Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies.
Nature, 509, 2014
4OD1
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CRYSTAL STRUCTURE OF HUMAN FAB CAP256-VRC26.03, A POTENT V1V2-DIRECTED HIV-1 NEUTRALIZING ANTIBODY
Descriptor:CAP256-VRC26.03 heavy chain, CAP256-VRC26.03 light chain
Authors:Gorman, J., Doria-Rose, N.A., Schramm, C.A., Moore, P.L., Mascola, J.R., Shapiro, L., Morris, L., Kwong, P.D.
Deposit date:2014-01-09
Release date:2014-02-26
Last modified:2014-05-14
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies.
Nature, 509, 2014
4OD3
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CRYSTAL STRUCTURE OF HUMAN FAB CAP256-VRC26.07, A POTENT V1V2-DIRECTED HIV-1 NEUTRALIZING ANTIBODY
Descriptor:CAP256-VRC26.07 light chain, CAP256-VRC26.07 heavy chain, ZINC ION, ...
Authors:Gorman, J., Doria-Rose, N.A., Schramm, C.A., Moore, P.L., Mascola, J.R., Shapiro, L., Morris, L., Kwong, P.D.
Deposit date:2014-01-09
Release date:2014-02-26
Last modified:2014-05-14
Method:X-RAY DIFFRACTION (2.616 Å)
Cite:Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies.
Nature, 509, 2014
4ODH
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CRYSTAL STRUCTURE OF HUMAN FAB CAP256-VRC26.UCA, A POTENT V1V2-DIRECTED HIV-1 NEUTRALIZING ANTIBODY
Descriptor:CAP256-VRC26.UCA light chain, CAP256-VRC26.UCA heavy chain
Authors:Gorman, J., Doria-Rose, N.A., Schramm, C.A., Moore, P.L., Mascola, J.R., Shapiro, L., Morris, L., Kwong, P.D.
Deposit date:2014-01-10
Release date:2014-02-26
Last modified:2014-05-14
Method:X-RAY DIFFRACTION (2.894 Å)
Cite:Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies.
Nature, 509, 2014