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1ZZP
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BU of 1zzp by Molmil
Solution structure of the F-actin binding domain of Bcr-Abl/c-Abl
Descriptor: Proto-oncogene tyrosine-protein kinase ABL1
Authors:Hantschel, O, Wiesner, S, Guttler, T, Mackereth, C.D, Rix, L.L.R, Mikes, Z, Dehne, J, Gorlich, D, Sattler, M, Superti-Furga, G.
Deposit date:2005-06-14
Release date:2005-08-30
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Structural Basis for the Cytoskeletal Association of Bcr-Abl/c-Abl.
Mol.Cell, 19, 2005
6FVB
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BU of 6fvb by Molmil
Structure of Lph2 , a novel bidirectional nuclear transport receptor in S. cerevisiae
Descriptor: Importin beta-like protein KAP120
Authors:Vera Rodriguez, A, Huyton, T, Gorlich, D.
Deposit date:2018-03-01
Release date:2019-09-11
Method:X-RAY DIFFRACTION (3.297 Å)
Cite:Structure of Lph2 , a novel bidirectional nuclear transport receptor in S. cerevisiae
To Be Published
5MSE
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BU of 5mse by Molmil
GFP nuclear transport receptor mimic 3B8
Descriptor: Green fluorescent protein, IMIDAZOLE, SODIUM ION
Authors:Huyton, T, Gorlich, D.
Deposit date:2017-01-04
Release date:2018-05-02
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Surface Properties Determining Passage Rates of Proteins through Nuclear Pores.
Cell, 174, 2018
8CDS
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BU of 8cds by Molmil
Crystal structure of the xhNup93-Nb4i VHH antibody
Descriptor: 1,2-ETHANEDIOL, 5-Nup93 inhibitory VHH antibody, DI(HYDROXYETHYL)ETHER
Authors:Guttler, T, Colom, M.S, Gorlich, D.
Deposit date:2023-02-01
Release date:2024-02-21
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Crystal structure of the xhNup93-Nb4i VHH antibody
To Be Published
8CDT
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BU of 8cdt by Molmil
Crystal structure of the xNup93-Nb2t VHH antibody
Descriptor: 15-Nup93 tracking VHH antibody, GLYCEROL
Authors:Guttler, T, Colom, M.S, Gorlich, D.
Deposit date:2023-02-01
Release date:2024-02-21
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Crystal structure of the xNup93-Nb2t VHH antibody
To Be Published
1QMA
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BU of 1qma by Molmil
Nuclear Transport Factor 2 (NTF2) W7A mutant
Descriptor: NUCLEAR TRANSPORT FACTOR 2
Authors:Bayliss, R, Ribbeck, K, Akin, D, Kent, H.M, Feldherr, C.M, Gorlich, D, Stewart, M.J.
Deposit date:1999-09-23
Release date:2000-02-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Interaction Betweeen Ntf2 and Xfxfg-Containing Nucleoporins is Required to Mediate Nuclear Import of Ran-Gdp
J.Mol.Biol., 293, 1999
8Q94
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BU of 8q94 by Molmil
Crystal structure of The SARS-COV-2 BA.2.75 RBD with neutralizing-VHHs Re32D03 and Ma3B12
Descriptor: Nanobody Ma3B12, Nanobody Re32D03, Spike protein S1
Authors:Aksu, M, Guttler, T, Gorlich, D.
Deposit date:2023-08-19
Release date:2023-12-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Nanobodies to multiple spike variants and inhalation of nanobody-containing aerosols neutralize SARS-CoV-2 in cell culture and hamsters.
Antiviral Res., 221, 2023
8Q95
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BU of 8q95 by Molmil
Crystal structure of the SARS-CoV-2 BA.1 RBD with neutralizing-VHHs Ma16B06 and Ma3F05
Descriptor: Nanobody Ma16B06, Nanobody Ma3F05, Spike protein S1
Authors:Aksu, M, Rymarenko, O, Guttler, T, Gorlich, D.
Deposit date:2023-08-19
Release date:2023-12-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Nanobodies to multiple spike variants and inhalation of nanobody-containing aerosols neutralize SARS-CoV-2 in cell culture and hamsters.
Antiviral Res., 221, 2023
8Q93
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BU of 8q93 by Molmil
Crystal structure of the SARS-COV-2 RBD with neutralizing-VHHs Re30H02 and Re21D01
Descriptor: Nanobody Re21D01, Nanobody Re30H02, Spike protein S1
Authors:Aksu, M, Guttler, T, Rymarenko, O, Gorlich, D.
Deposit date:2023-08-19
Release date:2023-12-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Nanobodies to multiple spike variants and inhalation of nanobody-containing aerosols neutralize SARS-CoV-2 in cell culture and hamsters.
Antiviral Res., 221, 2023
6NYR
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BU of 6nyr by Molmil
The crystal structure of CroV588 a novel circular LRR protein structure
Descriptor: Crov588, GLYCEROL
Authors:Huyton, T, Jaiswal, M, Gorlich, D.
Deposit date:2019-02-12
Release date:2020-08-12
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.431 Å)
Cite:The crystal structure of CroV588 a novel circular LRR protein structure
To Be Published
6NYS
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BU of 6nys by Molmil
The crystal structure of CroV588 a novel circular LRR protein structure
Descriptor: 6-tungstotellurate(VI), crov588
Authors:Huyton, T, Jaiswal, M, Gorlich, D.
Deposit date:2019-02-12
Release date:2020-08-12
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The crystal structure of CroV588 a novel circular LRR protein structure
To Be Published
8Q7S
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BU of 8q7s by Molmil
Crystal structure of the SARS-CoV-2 RBD (Wuhan) with neutralizing VHHs Ma6F06 and Re21H01
Descriptor: 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, GLYCEROL, ...
Authors:Guttler, T, Aksu, M, Gorlich, D.
Deposit date:2023-08-16
Release date:2023-12-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Nanobodies to multiple spike variants and inhalation of nanobody-containing aerosols neutralize SARS-CoV-2 in cell culture and hamsters.
Antiviral Res., 221, 2023
7OLZ
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BU of 7olz by Molmil
Crystal structure of the SARS-CoV-2 RBD with neutralizing-VHHs Re5D06 and Re9F06
Descriptor: 3-[BENZYL(DIMETHYL)AMMONIO]PROPANE-1-SULFONATE, Nanobody Re5D06, Nanobody Re9F06, ...
Authors:Aksu, M, Guttler, T, Gorlich, D.
Deposit date:2021-05-20
Release date:2021-08-11
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Neutralization of SARS-CoV-2 by highly potent, hyperthermostable, and mutation-tolerant nanobodies.
Embo J., 40, 2021
7ON5
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BU of 7on5 by Molmil
Crystal structure of the SARS-CoV-2 neutralizing nanobody Re5D06
Descriptor: 1,2-ETHANEDIOL, ETHANOL, Nanobody Re5D06
Authors:Aksu, M, Guttler, T, Gorlich, D.
Deposit date:2021-05-25
Release date:2021-08-11
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Neutralization of SARS-CoV-2 by highly potent, hyperthermostable, and mutation-tolerant nanobodies.
Embo J., 40, 2021
3NC0
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BU of 3nc0 by Molmil
Crystal structure of the HIV-1 Rev NES-CRM1-RanGTP nuclear export complex (crystal II)
Descriptor: DI(HYDROXYETHYL)ETHER, Exportin-1, GLYCEROL, ...
Authors:Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D.
Deposit date:2010-06-04
Release date:2010-10-27
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
Nat.Struct.Mol.Biol., 17, 2010
3NBY
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BU of 3nby by Molmil
Crystal structure of the PKI NES-CRM1-RanGTP nuclear export complex
Descriptor: Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D.
Deposit date:2010-06-04
Release date:2010-10-27
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.42 Å)
Cite:NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
Nat.Struct.Mol.Biol., 17, 2010
3NBZ
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BU of 3nbz by Molmil
Crystal structure of the HIV-1 Rev NES-CRM1-RanGTP nuclear export complex (crystal I)
Descriptor: Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D.
Deposit date:2010-06-04
Release date:2010-10-27
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
Nat.Struct.Mol.Biol., 17, 2010
3NC1
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BU of 3nc1 by Molmil
Crystal structure of the CRM1-RanGTP complex
Descriptor: Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D.
Deposit date:2010-06-04
Release date:2010-10-27
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
Nat.Struct.Mol.Biol., 17, 2010
5C3L
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BU of 5c3l by Molmil
Structure of the metazoan Nup62.Nup58.Nup54 nucleoporin complex.
Descriptor: Nanobody Nb15, Nucleoporin Nup58, Nucleoporin Nup62, ...
Authors:Chug, H, Trakhanov, S, Hulsmann, B.B, Pleiner, T, Gorlich, D.
Deposit date:2015-06-17
Release date:2015-08-26
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of the metazoan Nup62Nup58Nup54 nucleoporin complex.
Science, 350, 2015
5C2U
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BU of 5c2u by Molmil
Ferredoxin-like domain of nucleoporin Nup54 bound to a nanobody
Descriptor: Nanobody, Nup54
Authors:Chug, H, Trakhanov, S, Hulsmann, B.B, Pleiner, T, Gorlich, D.
Deposit date:2015-06-16
Release date:2015-08-26
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structure of the metazoan Nup62Nup58Nup54 nucleoporin complex.
Science, 350, 2015
5DLQ
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BU of 5dlq by Molmil
Crystal structure of RanGTP-Exportin 4-eIF5A complex
Descriptor: Eukaryotic translation initiation factor 5A-1, Exportin-4, GTP-binding nuclear protein Ran, ...
Authors:Aksu, M, Trakhanov, S, Gorlich, D.
Deposit date:2015-09-07
Release date:2016-06-22
Last modified:2016-06-29
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure of the exportin Xpo4 in complex with RanGTP and the hypusine-containing translation factor eIF5A.
Nat Commun, 7, 2016
6Q84
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BU of 6q84 by Molmil
Crystal structure of RanGTP-Pdr6-eIF5A export complex
Descriptor: Eukaryotic translation initiation factor 5A-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Aksu, M, Trakhanov, S, Vera-Rodriguez, A, Gorlich, D.
Deposit date:2018-12-14
Release date:2019-05-01
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Structural basis for the nuclear import and export functions of the biportin Pdr6/Kap122.
J.Cell Biol., 218, 2019
6Q83
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BU of 6q83 by Molmil
Crystal structure of the biportin Pdr6 in complex with UBC9
Descriptor: Importin beta-like protein KAP122, UBC9
Authors:Aksu, M, Trakhanov, S, Vera-Rodriguez, A, Gorlich, D.
Deposit date:2018-12-14
Release date:2019-05-01
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (4.53 Å)
Cite:Structural basis for the nuclear import and export functions of the biportin Pdr6/Kap122.
J.Cell Biol., 218, 2019
6Q82
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BU of 6q82 by Molmil
Crystal structure of the biportin Pdr6 in complex with RanGTP
Descriptor: GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, Importin beta-like protein KAP122, ...
Authors:Aksu, M, Vera-Rodriguez, A, Trakhanov, S, Gorlich, D.
Deposit date:2018-12-14
Release date:2019-05-01
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (2.994 Å)
Cite:Structural basis for the nuclear import and export functions of the biportin Pdr6/Kap122.
J.Cell Biol., 218, 2019
6QUG
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BU of 6qug by Molmil
GHK tagged MBP-Nup98(1-29)
Descriptor: COPPER (II) ION, Maltodextrin-binding protein,Nucleoporin, putative, ...
Authors:Huyton, T, Gorlich, D.
Deposit date:2019-02-27
Release date:2020-05-27
Last modified:2020-12-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The copper(II)-binding tripeptide GHK, a valuable crystallization and phasing tag for macromolecular crystallography.
Acta Crystallogr D Struct Biol, 76, 2020

 

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