Author results

1UMY
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BHMT FROM RAT LIVER
分子名称:Betaine--homocysteine S-methyltransferase 1, ZINC ION, BETA-MERCAPTOETHANOL
著者Gonzalez, B., Pajares, M.A., Sanz-Aparicio, J.
登録日2003-09-02
公開日2004-05-06
最終更新日2018-12-05
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of rat liver betaine homocysteine s-methyltransferase reveals new oligomerization features and conformational changes upon substrate binding.
J. Mol. Biol., 338, 2004
1O90
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METHIONINE ADENOSYLTRANSFERASE COMPLEXED WITH A L-METHIONINE ANALOGUE
分子名称:S-ADENOSYLMETHIONINE SYNTHETASE, (2S,4S)-2-AMINO-4,5-EPOXIPENTANOIC ACID, PHOSPHATE ION, ...
著者Gonzalez, B., Pajares, M.A., Hermoso, J.A., Sanz-Aparicio, J.
登録日2002-12-10
公開日2003-08-07
最終更新日2018-05-30
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal Structures of Methionine Adenosyltransferase Complexed with Substrates and Products Reveal the Methionine-ATP Recognition and Give Insights Into the Catalytic Mechanism
J.Mol.Biol., 331, 2003
1O92
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METHIONINE ADENOSYLTRANSFERASE COMPLEXED WITH ADP AND A L-METHIONINE ANALOGUE
分子名称:S-ADENOSYLMETHIONINE SYNTHETASE, L-2-AMINO-4-METHOXY-CIS-BUT-3-ENOIC ACID, PHOSPHATE ION, ...
著者Gonzalez, B., Pajares, M.A., Hermoso, J.A., Sanz-Aparicio, J.
登録日2002-12-10
公開日2003-08-07
最終更新日2018-05-30
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Crystal Structures of Methionine Adenosyltransferase Complexed with Substrates and Products Reveal the Methionine-ATP Recognition and Give Insights Into the Catalytic Mechanism
J.Mol.Biol., 331, 2003
1O93
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METHIONINE ADENOSYLTRANSFERASE COMPLEXED WITH ATP AND A L-METHIONINE ANALOGUE
分子名称:S-ADENOSYLMETHIONINE SYNTHETASE, (2S,4S)-2-AMINO-4,5-EPOXIPENTANOIC ACID, PHOSPHATE ION, ...
著者Gonzalez, B., Pajares, M.A., Hermoso, J.A., Sanz-Aparicio, J.
登録日2002-12-10
公開日2003-08-07
最終更新日2018-05-30
実験手法X-RAY DIFFRACTION (3.49 Å)
主引用文献Crystal Structures of Methionine Adenosyltransferase Complexed with Substrates and Products Reveal the Methionine-ATP Recognition and Give Insights Into the Catalytic Mechanism
J.Mol.Biol., 331, 2003
1O9T
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METHIONINE ADENOSYLTRANSFERASE COMPLEXED WITH BOTH SUBSTRATES ATP AND METHIONINE
分子名称:S-ADENOSYLMETHIONINE SYNTHETASE, METHIONINE, PHOSPHATE ION, ...
著者Gonzalez, B., Pajares, M.A., Hermoso, J.A., Sanz-Aparicio, J.
登録日2002-12-18
公開日2003-08-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal Structures of Methionine Adenosyltransferase Complexed with Substrates and Products Reveal the Methionine-ATP Recognition and Give Insights Into the Catalytic Mechanism
J.Mol.Biol., 331, 2003
1QM4
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METHIONINE ADENOSYLTRANSFERASE COMPLEXED WITH A L-METHIONINE ANALOGUE
分子名称:METHIONINE ADENOSYLTRANSFERASE, ALPHA FORM, L-2-AMINO-4-METHOXY-CIS-BUT-3-ENOIC ACID, ...
著者Gonzalez, B., Pajares, M.A., Hermoso, J.A., Sanz-Aparicio, J.
登録日1999-09-20
公開日2000-09-21
最終更新日2018-05-30
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献The Crystal Structure of Tetrameric Methionine Adenosyltransferase from Rat Liver Reveals the Methionine-Binding Site
J.Mol.Biol., 300, 2000
1W2C
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HUMAN INOSITOL (1,4,5) TRISPHOSPHATE 3-KINASE COMPLEXED WITH MN2+/AMPPNP/INS(1,4,5)P3
分子名称:INOSITOL-TRISPHOSPHATE 3-KINASE A, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, ...
著者Gonzalez, B., Schell, M.J., Irvine, R.F., Williams, R.L.
登録日2004-07-01
公開日2004-09-09
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure of a Human Inositol 1,4,5-Trisphosphate 3-Kinase; Substrate Binding Reveals Why It is not a Phosphoinositide 3-Kinase
Mol.Cell, 15, 2004
1W2D
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HUMAN INOSITOL (1,4,5)-TRISPHOSPHATE 3-KINASE COMPLEXED WITH MN2+/ADP/INS(1,3,4,5)P4
分子名称:INOSITOL-TRISPHOSPHATE 3-KINASE A, ADENOSINE-5'-DIPHOSPHATE, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, ...
著者Gonzalez, B., Schell, M.J., Irvine, R.F., Williams, R.L.
登録日2004-07-01
公開日2004-09-09
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Structure of a Human Inositol 1,4,5-Trisphosphate 3-Kinase; Substrate Binding Reveals Why It is not a Phosphoinositide 3-Kinase
Mol.Cell, 15, 2004
1W2F
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HUMAN INOSITOL (1,4,5)-TRISPHOSPHATE 3-KINASE SUBSTITUTED WITH SELENOMETHIONINE
分子名称:INOSITOL-TRISPHOSPHATE 3-KINASE A, SULFATE ION
著者Gonzalez, B., Schell, M.J., Irvine, R.F., Williams, R.L.
登録日2004-07-01
公開日2004-09-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of a Human Inositol 1,4,5-Trisphosphate 3-Kinase; Substrate Binding Reveals Why It is not a Phosphoinositide 3-Kinase
Mol.Cell, 15, 2004
2XAL
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LEAD DERIVATIVE OF INOSITOL 1,3,4,5,6-PENTAKISPHOSPHATE 2-KINASE FROM A. THALIANA IN COMPLEX WITH ADP AND IP6.
分子名称:INOSITOL-PENTAKISPHOSPHATE 2-KINASE, INOSITOL 1,2,3,4,5,6-HEXAKISPHOSPHATE, LEAD (II) ION, ...
著者Gonzalez, B., Banos-Sanz, J.I., Villate, M., Brearley, C.A., Sanz-Aparicio, J.
登録日2010-03-31
公開日2010-05-19
最終更新日2019-11-20
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Inositol 1,3,4,5,6-Pentakisphosphate 2-Kinase is a Distant Ipk Member with a Singular Inositide Binding Site for Axial 2-Oh Recognition.
Proc.Natl.Acad.Sci.USA, 107, 2010
2XAM
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INOSITOL 1,3,4,5,6-PENTAKISPHOSPHATE 2-KINASE FROM A. THALIANA IN COMPLEX WITH ADP AND IP6.
分子名称:INOSITOL-PENTAKISPHOSPHATE 2-KINASE, INOSITOL 1,2,3,4,5,6-HEXAKISPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ...
著者Gonzalez, B., Banos-Sanz, J.I., Villate, M., Brearley, C.A., Sanz-Aparicio, J.
登録日2010-03-31
公開日2010-05-19
最終更新日2018-06-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Inositol 1,3,4,5,6-Pentakisphosphate 2-Kinase is a Distant Ipk Member with a Singular Inositide Binding Site for Axial 2-Oh Recognition.
Proc.Natl.Acad.Sci.USA, 107, 2010
2XAN
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INOSITOL 1,3,4,5,6-PENTAKISPHOSPHATE 2-KINASE FROM A. THALIANA IN COMPLEX WITH AMP PNP AND IP5
分子名称:INOSITOL-PENTAKISPHOSPHATE 2-KINASE, MYO-INOSITOL-(1,3,4,5,6)-PENTAKISPHOSPHATE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Gonzalez, B., Banos-Sanz, J.I., Villate, M., Brearley, C.A., Sanz-Aparicio, J.
登録日2010-03-31
公開日2010-05-19
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Inositol 1,3,4,5,6-Pentakisphosphate 2-Kinase is a Distant Ipk Member with a Singular Inositide Binding Site for Axial 2-Oh Recognition.
Proc.Natl.Acad.Sci.USA, 107, 2010
2XAO
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INOSITOL 1,3,4,5,6-PENTAKISPHOSPHATE 2-KINASE FROM A. THALIANA IN COMPLEX WITH IP5
分子名称:INOSITOL-PENTAKISPHOSPHATE 2-KINASE, MYO-INOSITOL-(1,3,4,5,6)-PENTAKISPHOSPHATE, ZINC ION
著者Gonzalez, B., Banos-Sanz, J.I., Villate, M., Brearley, C.A., Sanz-Aparicio, J.
登録日2010-03-31
公開日2010-05-19
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Inositol 1,3,4,5,6-Pentakisphosphate 2-Kinase is a Distant Ipk Member with a Singular Inositide Binding Site for Axial 2-Oh Recognition.
Proc.Natl.Acad.Sci.USA, 107, 2010
2XAR
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INOSITOL 1,3,4,5,6-PENTAKISPHOSPHATE 2-KINASE FROM A. THALIANA IN COMPLEX WITH IP6.
分子名称:INOSITOL-PENTAKISPHOSPHATE 2-KINASE, INOSITOL 1,2,3,4,5,6-HEXAKISPHOSPHATE, ZINC ION
著者Gonzalez, B., Banos-Sanz, J.I., Villate, M., Brearley, C.A., Sanz-Aparicio, J.
登録日2010-03-31
公開日2010-05-19
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Inositol 1,3,4,5,6-Pentakisphosphate 2-Kinase is a Distant Ipk Member with a Singular Inositide Binding Site for Axial 2-Oh Recognition.
Proc.Natl.Acad.Sci.USA, 107, 2010
5MW8
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INOSITOL 1,3,4,5,6-PENTAKISPHOSPHATE 2-KINASE FROM M. MUSCULUS IN COMPLEX WITH ATP AND IP5
分子名称:Inositol-pentakisphosphate 2-kinase, ADENOSINE-5'-TRIPHOSPHATE, MYO-INOSITOL-(1,3,4,5,6)-PENTAKISPHOSPHATE, ...
著者Franco-Echevarria, E., Sanz-Aparicio, J., Gonzalez, B.
登録日2017-01-18
公開日2017-05-10
最終更新日2017-07-05
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The crystal structure of mammalian inositol 1,3,4,5,6-pentakisphosphate 2-kinase reveals a new zinc-binding site and key features for protein function.
J. Biol. Chem., 292, 2017
5MWL
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INOSITOL 1,3,4,5,6-PENTAKISPHOSPHATE 2-KINASE FROM M. MUSCULUS IN COMPLEX WITH ATP AND IP5
分子名称:Inositol-pentakisphosphate 2-kinase, ADENOSINE-5'-TRIPHOSPHATE, MYO-INOSITOL-(1,3,4,5,6)-PENTAKISPHOSPHATE, ...
著者Franco-Echevarria, E., Sanz-Aparicio, J., Gonzalez, B.
登録日2017-01-18
公開日2017-05-10
最終更新日2019-10-16
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The crystal structure of mammalian inositol 1,3,4,5,6-pentakisphosphate 2-kinase reveals a new zinc-binding site and key features for protein function.
J. Biol. Chem., 292, 2017
5MWM
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INOSITOL 1,3,4,5,6-PENTAKISPHOSPHATE 2-KINASE FROM M. MUSCULUS IN COMPLEX WITH IP6
分子名称:Inositol-pentakisphosphate 2-kinase, INOSITOL 1,2,3,4,5,6-HEXAKISPHOSPHATE, ZINC ION
著者Franco-Echevarria, E., Sanz-Aparicio, J., Gonzalez, B.
登録日2017-01-18
公開日2017-05-10
最終更新日2019-10-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The crystal structure of mammalian inositol 1,3,4,5,6-pentakisphosphate 2-kinase reveals a new zinc-binding site and key features for protein function.
J. Biol. Chem., 292, 2017
5O1W
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STRUCTURE OF NRD1 RNA BINDING DOMAIN
分子名称:Protein NRD1, 1,2-ETHANEDIOL
著者Franco-Echevarria, E., Perez-Canadillas, J.M., Gonzalez, B.
登録日2017-05-19
公開日2017-08-02
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The structure of transcription termination factor Nrd1 reveals an original mode for GUAA recognition.
Nucleic Acids Res., 45, 2017
5O1X
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STRUCTURE OF NRD1 RNA BINDING DOMAIN
分子名称:Protein NRD1, 1,2-ETHANEDIOL, THIOCYANATE ION
著者Franco-Echevarria, E., Perez-Canadillas, J.M., Gonzalez, B.
登録日2017-05-19
公開日2017-08-02
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The structure of transcription termination factor Nrd1 reveals an original mode for GUAA recognition.
Nucleic Acids Res., 45, 2017
5O1Y
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STRUCTURE OF NRD1 RNA BINDING DOMAIN IN COMPLEX WITH RNA (GUAA)
分子名称:Protein NRD1, RNA (5'-R(*GP*UP*AP*A)-3'), 1,2-ETHANEDIOL, ...
著者Franco-Echevarria, E., Perez-Canadillas, J.M., Gonzalez, B.
登録日2017-05-19
公開日2017-08-02
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献The structure of transcription termination factor Nrd1 reveals an original mode for GUAA recognition.
Nucleic Acids Res., 45, 2017
5O1Z
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STRUCTURE OF NRD1 RNA BINDING DOMAIN IN COMPLEX WITH RNA (CGUAAA)
分子名称:Protein NRD1, RNA (5'-R(*CP*GP*UP*AP*AP*A)-3')
著者Franco-Echevarria, E., Perez-Canadillas, J.M., Gonzalez, B.
登録日2017-05-19
公開日2017-08-02
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献The structure of transcription termination factor Nrd1 reveals an original mode for GUAA recognition.
Nucleic Acids Res., 45, 2017
5O20
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STRUCTURE OF NRD1 RNA BINDING DOMAIN IN COMPLEX WITH RNA (UUAGUAAUCC)
分子名称:Protein NRD1, RNA (5'-R(*UP*AP*GP*UP*AP*AP*UP*C)-3'), 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
著者Franco-Echevarria, E., Perez-Canadillas, J.M., Gonzalez, B.
登録日2017-05-19
公開日2017-08-02
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (3.53 Å)
主引用文献The structure of transcription termination factor Nrd1 reveals an original mode for GUAA recognition.
Nucleic Acids Res., 45, 2017
1E4I
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2-DEOXY-2-FLUORO-BETA-D-GLUCOSYL/ENZYME INTERMEDIATE COMPLEX OF THE BETA-GLUCOSIDASE FROM BACILLUS POLYMYXA
分子名称:BETA-GLUCOSIDASE, 2-deoxy-2-fluoro-alpha-D-glucopyranose, 2,4-DINITROPHENYL 2-DEOXY-2-FLUORO-BETA-D-GLUCOPYRANOSIDE
著者Sanz-Aparicio, J., Gonzalez, B., Hermoso, J.A., Arribas, J.C., Canada, F.J., Polaina, J.
登録日2000-07-06
公開日2001-07-05
最終更新日2018-06-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis of Increased Resistance to Thermal Denaturation Induced by Single Amino Acid Substitution in the Sequence of Beta-Glucosidase a from Bacillus Polymyxa.
Proteins: Struct.,Funct., Genet., 33, 1998
2V4L
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COMPLEX OF HUMAN PHOSPHOINOSITIDE 3-KINASE CATALYTIC SUBUNIT GAMMA (P110 GAMMA) WITH PIK-284
分子名称:PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT GAMMA ISOFORM, 3-[4-AMINO-1-(1-METHYLETHYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL]PHENOL
著者Apsel, B., Gonzalez, B., Blair, J.A., Nazif, T.M., Feldman, M.E., Williams, R.L., Shokat, K.M., Knight, Z.A.
登録日2008-09-25
公開日2008-10-14
最終更新日2013-04-17
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Targeted Polypharmacology: Discovery of Dual Inhibitors of Tyrosine and Phosphoinositide Kinases.
Nat.Chem.Biol., 4, 2008
2CHW
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A PHARMACOLOGICAL MAP OF THE PI3-K FAMILY DEFINES A ROLE FOR P110 ALPHA IN SIGNALING: THE STRUCTURE OF COMPLEX OF PHOSPHOINOSITIDE 3- KINASE GAMMA WITH INHIBITOR PIK-39
分子名称:PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT GAMMA ISOFORM, 2-((9H-PURIN-6-YLTHIO)METHYL)-5-CHLORO-3-(2-METHOXYPHENYL)QUINAZOLIN-4(3H)-ONE
著者Knight, Z.A., Gonzalez, B., Feldman, M.E., Zunder, E.R., Goldenberg, D.D., Williams, O., Loewith, R., Stokoe, D., Balla, A., Toth, B., Balla, T., Weiss, W.A., Williams, R.L., Shokat, K.M.
登録日2006-03-16
公開日2006-05-22
最終更新日2019-10-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A Pharmacological Map of the Pi3-K Family Defines a Role for P110Alpha in Signaling
Cell(Cambridge,Mass.), 125, 2006