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6GWM
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BU of 6gwm by Molmil
Solution structure of rat RIP2 caspase recruitment domain
Descriptor: Receptor-interacting serine/threonine-protein kinase 2
Authors:Mineev, K.S, Goncharuk, S.A, Artemieva, L.E, Arseniev, A.S.
Deposit date:2018-06-25
Release date:2018-10-31
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:CARD domain of rat RIP2 kinase: Refolding, solution structure, pH-dependent behavior and protein-protein interactions.
PLoS ONE, 13, 2018
7AVB
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BU of 7avb by Molmil
Solution structure of the fluorogen-activating protein FAST in the apo state
Descriptor: FAST
Authors:Mineev, K.S, Goncharuk, S.A, Baranov, M.S.
Deposit date:2020-11-05
Release date:2021-04-28
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:NanoFAST: structure-based design of a small fluorogen-activating protein with only 98 amino acids.
Chem Sci, 12, 2021
7AVA
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BU of 7ava by Molmil
Solution structure of the fluorogen-activating protein FAST in complex with the ligand N871b
Descriptor: (5~{Z})-5-[(2-methoxy-4-oxidanyl-phenyl)methylidene]-3-methyl-2-[(~{E})-2-pyridin-4-ylethenyl]imidazol-4-one, FAST
Authors:Mineev, K.S, Goncharuk, S.A, Baranov, M.S.
Deposit date:2020-11-05
Release date:2021-04-28
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:NanoFAST: structure-based design of a small fluorogen-activating protein with only 98 amino acids.
Chem Sci, 12, 2021
6HJ7
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BU of 6hj7 by Molmil
The NMR structure of NRADD death domain
Descriptor: Death domain-containing membrane protein NRADD
Authors:Nadezhdin, K.D, Mineev, K.S, Goncharuk, S.A, Arseniev, A.S.
Deposit date:2018-09-01
Release date:2019-05-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:NMR structure of a full-length single-pass membrane protein NRADD.
Proteins, 87, 2019
5NAM
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BU of 5nam by Molmil
NMR structure of TLR4 transmembrane domain (624-670) in DMPG/DHPC bicelles
Descriptor: Toll-like receptor 4
Authors:Mineev, K.S, Goncharuk, S.A, Goncharuk, M.V, Arseniev, A.S.
Deposit date:2017-02-28
Release date:2017-09-06
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Spatial structure of TLR4 transmembrane domain in bicelles provides the insight into the receptor activation mechanism.
Sci Rep, 7, 2017
5NAO
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BU of 5nao by Molmil
NMR structure of TLR4 transmembrane domain (624-657) in DPC micelles
Descriptor: Toll-like receptor 4
Authors:Mineev, K.S, Goncharuk, S.A, Goncharuk, M.V, Arseniev, A.S.
Deposit date:2017-02-28
Release date:2018-03-21
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Spatial structure of TLR4 transmembrane domain in bicelles provides the insight into the receptor activation mechanism.
Sci Rep, 7, 2017
8AO0
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BU of 8ao0 by Molmil
Solution structure of nanoFAST/HBR-DOM2 complex
Descriptor: (5~{Z})-5-[(2,5-dimethoxy-4-oxidanyl-phenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one, Photoactive yellow protein
Authors:Lushpa, V.A, Goncharuk, M.V, Goncharuk, S.A, Baleeva, N.S, Baranov, M.S, Mineev, K.S.
Deposit date:2022-08-08
Release date:2022-11-23
Method:SOLUTION NMR
Cite:Spatial Structure of NanoFAST in the Apo State and in Complex with its Fluorogen HBR-DOM2.
Int J Mol Sci, 23, 2022
8AO1
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BU of 8ao1 by Molmil
solution structure of nanoFAST fluorogen-activating protein in the apo state
Descriptor: nanoFAST
Authors:Lushpa, V.A, Goncharuk, M.V, Goncharuk, S.A, Baranov, M.S, Mineev, K.S.
Deposit date:2022-08-08
Release date:2022-11-23
Method:SOLUTION NMR
Cite:Spatial Structure of NanoFAST in the Apo State and in Complex with its Fluorogen HBR-DOM2.
Int J Mol Sci, 23, 2022
8AR2
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BU of 8ar2 by Molmil
Solution structure of TLR5 transmembrane and cytoplasmic juxtamembrane regions
Descriptor: Toll-like receptor 5
Authors:Shabalkina, A.V, Kornilov, F.D, Goncharuk, M.V, Goncharuk, S.A, Arseniev, A.S, Mineev, K.S.
Deposit date:2022-08-15
Release date:2023-03-22
Last modified:2023-03-29
Method:SOLUTION NMR
Cite:The architecture of transmembrane and cytoplasmic juxtamembrane regions of Toll-like receptors.
Nat Commun, 14, 2023
8AR3
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BU of 8ar3 by Molmil
Solution structure of TLR9 transmembrane and cytoplasmic juxtamembrane regions
Descriptor: Toll-like receptor 9
Authors:Kornilov, F.D, Shabalkina, A.V, Goncharuk, M.V, Goncharuk, S.A, Arseniev, A.S, Mineev, K.S.
Deposit date:2022-08-15
Release date:2023-03-22
Last modified:2023-03-29
Method:SOLUTION NMR
Cite:The architecture of transmembrane and cytoplasmic juxtamembrane regions of Toll-like receptors.
Nat Commun, 14, 2023
8AR1
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BU of 8ar1 by Molmil
Solution structure of TLR3 transmembrane and cytoplasmic juxtamembrane regions
Descriptor: Toll-like receptor 3
Authors:Kornilov, F.D, Shabalkina, A.V, Goncharuk, M.V, Goncharuk, S.A, Arseniev, A.S, Mineev, K.S.
Deposit date:2022-08-15
Release date:2023-03-22
Last modified:2023-03-29
Method:SOLUTION NMR
Cite:The architecture of transmembrane and cytoplasmic juxtamembrane regions of Toll-like receptors.
Nat Commun, 14, 2023
8AR0
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BU of 8ar0 by Molmil
Solution structure of TLR2 transmembrane and cytoplasmic juxtamembrane regions
Descriptor: Toll-like receptor 2
Authors:Kornilov, F.D, Shabalkina, A.V, Goncharuk, M.V, Goncharuk, S.A, Arseniev, A.S, Mineev, K.S.
Deposit date:2022-08-15
Release date:2023-03-22
Last modified:2023-03-29
Method:SOLUTION NMR
Cite:The architecture of transmembrane and cytoplasmic juxtamembrane regions of Toll-like receptors.
Nat Commun, 14, 2023
8C18
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BU of 8c18 by Molmil
Solution structure of carotenoid-binding protein AstaPo1 in complex with astaxanthin
Descriptor: ASTAXANTHIN, Astaxanthin binding fasciclin family protein
Authors:Kornilov, F.D, Savitskaya, A.G, Slonimskiy, Y.B, Goncharuk, S.A, Sluchanko, N.N, Mineev, K.S.
Deposit date:2022-12-20
Release date:2023-04-05
Last modified:2023-05-17
Method:SOLUTION NMR
Cite:Structural basis for the ligand promiscuity of the neofunctionalized, carotenoid-binding fasciclin domain protein AstaP.
Commun Biol, 6, 2023
2LZL
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BU of 2lzl by Molmil
FGFR3tm
Descriptor: Fibroblast growth factor receptor 3
Authors:Lesovoy, D.M, Bocharov, E.V, Goncharuk, S.A, Arseniev, A.S.
Deposit date:2012-10-04
Release date:2013-10-09
Last modified:2013-11-27
Method:SOLUTION NMR
Cite:Structure of FGFR3 Transmembrane Domain Dimer: Implications for Signaling and Human Pathologies.
Structure, 21, 2013
2MK9
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BU of 2mk9 by Molmil
Spatial structure of the dimeric transmembrane domain of Toll-like receptor 3
Descriptor: Toll-like receptor 3
Authors:Mineev, K.S, Goncharuk, S.A, Arseniev, A.S.
Deposit date:2014-02-04
Release date:2014-09-17
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Toll-like receptor 3 transmembrane domain is able to perform various homotypic interactions: An NMR structural study.
Febs Lett., 588, 2014
7AV6
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BU of 7av6 by Molmil
FAST in a domain-swapped dimer form
Descriptor: FORMIC ACID, Photoactive yellow protein
Authors:Bukhdruker, S, Remeeva, A, Ruchkin, D, Gorbachev, D, Povarova, N, Mineev, K, Goncharuk, S, Baranov, M, Mishin, A, Borshchevskiy, V.
Deposit date:2020-11-04
Release date:2021-06-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:NanoFAST: structure-based design of a small fluorogen-activating protein with only 98 amino acids.
Chem Sci, 12, 2021
2N90
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BU of 2n90 by Molmil
TrkA transmembrane domain NMR structure in DPC micelles
Descriptor: High affinity nerve growth factor receptor
Authors:Nadezhdin, K, Goncharuk, S, Arseniev, A.
Deposit date:2015-10-29
Release date:2016-11-09
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural basis of the transmembrane domain dimerization and rotation in the activation mechanism of the TRKA receptor by nerve growth factor.
J.Biol.Chem., 295, 2020
7NT7
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BU of 7nt7 by Molmil
Solution structure of toll like receptor 1 (TLR1) TIR domain
Descriptor: Toll-like receptor 1
Authors:Mineev, K.S, Lushpa, V.A, Goncharuk, M.V.
Deposit date:2021-03-09
Release date:2021-08-25
Last modified:2021-10-13
Method:SOLUTION NMR
Cite:Modulation of Toll-like receptor 1 intracellular domain structure and activity by Zn 2+ ions.
Commun Biol, 4, 2021
7NUX
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BU of 7nux by Molmil
Crystal structure of the TIR domain of human TLR1 (crystallised without ZN2+ ions)
Descriptor: Toll-like receptor 1
Authors:Vakhrameev, D.D, Luginina, A.P, Shevtsov, M.B, Lushpa, V.A, Mineev, K.S, Borshchevskiy, V.I.
Deposit date:2021-03-15
Release date:2021-08-25
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Modulation of Toll-like receptor 1 intracellular domain structure and activity by Zn 2+ ions.
Commun Biol, 4, 2021
7NUW
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BU of 7nuw by Molmil
Crystal structure of the TIR domain of human TLR1 (crystallised with Zn2+ ions)
Descriptor: Toll-like receptor 1
Authors:Vakhrameev, D.D, Luginina, A.P, Shevtsov, M.B, Lushpa, V.A, Mineev, K.S, Borshchevskiy, V.I.
Deposit date:2021-03-15
Release date:2021-08-25
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Modulation of Toll-like receptor 1 intracellular domain structure and activity by Zn 2+ ions.
Commun Biol, 4, 2021
2MJO
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BU of 2mjo by Molmil
NMR structure of p75 transmembrane domain C257A mutant in DPC micelles
Descriptor: Tumor necrosis factor receptor superfamily member 16
Authors:Nadezhdin, K, Arseniev, A, Goncharuk, S, Mineev, K.
Deposit date:2014-01-15
Release date:2015-01-28
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural Basis of p75 Transmembrane Domain Dimerization.
J. Biol. Chem., 291, 2016
2MIC
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BU of 2mic by Molmil
NMR structure of p75 transmembrane domain in DPC micelles
Descriptor: Tumor necrosis factor receptor superfamily member 16
Authors:Nadezhdin, K, Arseniev, A, Goncharuk, S, Mineev, K.
Deposit date:2013-12-12
Release date:2014-12-24
Last modified:2017-09-06
Method:SOLUTION NMR
Cite:Structural Basis of p75 Transmembrane Domain Dimerization.
J. Biol. Chem., 291, 2016
2MKA
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BU of 2mka by Molmil
Spatial structure of the Toll-like receptor 3 transmembrane domain in the trimeric state
Descriptor: Toll-like receptor 3
Authors:Mineev, K, Gonscharuk, S.A, Arseniev, A.S.
Deposit date:2014-02-04
Release date:2014-09-17
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Toll-like receptor 3 transmembrane domain is able to perform various homotypic interactions: An NMR structural study.
Febs Lett., 588, 2014
5OEK
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BU of 5oek by Molmil
Putative active dimeric state of GHR transmembrane domain
Descriptor: Growth hormone receptor
Authors:Lesovoy, D.M, Bocharov, E.V, Bocharova, O.V, Urban, A.S, Arseniev, A.S.
Deposit date:2017-07-08
Release date:2018-04-11
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural basis of the signal transduction via transmembrane domain of the human growth hormone receptor.
Biochim. Biophys. Acta, 1862, 2018
5OHD
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BU of 5ohd by Molmil
Putative inactive (dormant) dimeric state of GHR transmembrane domain
Descriptor: Growth hormone receptor
Authors:Lesovoy, D.M, Bocharov, E.V, Bocharova, O.V, Urban, A.S, Arseniev, A.S.
Deposit date:2017-07-15
Release date:2018-04-11
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural basis of the signal transduction via transmembrane domain of the human growth hormone receptor.
Biochim. Biophys. Acta, 1862, 2018

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