Author results

1PYT
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TERNARY COMPLEX OF PROCARBOXYPEPTIDASE A, PROPROTEINASE E, AND CHYMOTRYPSINOGEN C
Descriptor:PROCARBOXYPEPTIDASE A, PROPROTEINASE E, CHYMOTRYPSINOGEN C, ...
Authors:Gomis-Ruth, F.X., Gomez, M., Bode, W., Huber, R., Aviles, F.X.
Deposit date:1995-06-21
Release date:1997-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:The three-dimensional structure of the native ternary complex of bovine pancreatic procarboxypeptidase A with proproteinase E and chymotrypsinogen C.
EMBO J., 14, 1995
1GVL
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HUMAN PROKALLIKREIN 6 (HK6)/ PROZYME/ PROPROTEASE M/ PRONEUROSIN
Descriptor:KALLIKREIN 6
Authors:Gomis-Ruth, F.X., Bayes, A., Sotiropoulou, G., Pampalakis, G., Tsetsenis, T., Villegas, V., Aviles, F.X., Coll, M.
Deposit date:2002-02-14
Release date:2002-05-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Structure of Human Prokallikrein 6 Reveals a Novel Activation Mechanism for the Kallikrein Family.
J.Biol.Chem., 277, 2002
1GL6
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PLASMID COUPLING PROTEIN TRWB IN COMPLEX WITH THE NON-HYDROLYSABLE GTP ANALOGUE GDPNP
Descriptor:ATPASE, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, CHLORIDE ION, ...
Authors:Gomis-Ruth, F.X., Moncalian, G., De La cruz, F., Coll, M.
Deposit date:2001-08-28
Release date:2002-05-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Bacterial Conjugation Protein Trwb Resembles Ring Helicases and F1-ATPase
Nature, 409, 2001
1GKI
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PLASMID COUPLING PROTEIN TRWB IN COMPLEX WITH ADP AND MG2+.
Descriptor:CONJUGAL TRANSFER PROTEIN TRWB, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Gomis-Ruth, F.X., Moncalian, G., De La cruz, F., Coll, M.
Deposit date:2001-08-14
Release date:2002-05-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Bacterial Conjugation Protein Trwb Resembles Ring Helicases and F1-ATPase
Nature, 409, 2001
1GL7
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PLASMID COUPLING PROTEIN TRWB IN COMPLEX WITH THE NON-HYDROLISABLE ATP-ANALOGUE ADPNP.
Descriptor:CONJUGAL TRANSFER PROTEIN TRWB, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, CHLORIDE ION
Authors:Gomis-Ruth, F.X., Moncalian, G., De La cruz, F., Coll, M.
Deposit date:2001-08-28
Release date:2002-05-16
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Bacterial Conjugation Protein Trwb Resembles Ring Helicases and F1-ATPase
Nature, 409, 2001
1H2C
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EBOLA VIRUS MATRIX PROTEIN VP40 N-TERMINAL DOMAIN IN COMPLEX WITH RNA (HIGH-RESOLUTION VP40[55-194] VARIANT).
Descriptor:MATRIX PROTEIN VP40, 5'-R(*UP*GP*AP)-3'
Authors:Gomis-Ruth, F.X., Dessen, A., Bracher, A., Klenk, H.D., Weissenhorn, W.
Deposit date:2002-08-05
Release date:2003-04-10
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The Matrix Protein Vp40 from Ebola Virus Octamerizes Into Pore-Like Structures with Specific RNA Binding Properties
Structure, 11, 2003
1H2D
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EBOLA VIRUS MATRIX PROTEIN VP40 N-TERMINAL DOMAIN IN COMPLEX WITH RNA (LOW-RESOLUTION VP40[31-212] VARIANT).
Descriptor:MATRIX PROTEIN VP40, 5'-R(*UP*GP*AP)-3', CHLORIDE ION
Authors:Gomis-Ruth, F.X., Dessen, A., Bracher, A., Klenk, H.D., Weissenhorn, W.
Deposit date:2002-08-06
Release date:2003-04-10
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Matrix Protein Vp40 from Ebola Virus Octamerizes Into Pore-Like Structures with Specific RNA Binding Properties
Structure, 11, 2003
1PEX
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COLLAGENASE-3 (MMP-13) C-TERMINAL HEMOPEXIN-LIKE DOMAIN
Descriptor:COLLAGENASE-3, SULFATE ION, CHLORIDE ION, ...
Authors:Gomis-Ruth, F.X., Gohlke, U., Betz, M., Knauper, V., Murphy, G., Lopez-Otin, C., Bode, W.
Deposit date:1996-05-24
Release date:1996-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The helping hand of collagenase-3 (MMP-13): 2.7 A crystal structure of its C-terminal haemopexin-like domain.
J.Mol.Biol., 264, 1996
6SAZ
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CLEAVED HUMAN FETUIN-B IN COMPLEX WITH CRAYFISH ASTACIN
Descriptor:Astacin, Fetuin-B, ZINC ION, ...
Authors:Gomis-Ruth, F.X., Guevara, T., Cuppari, A., Korschgen, H., Schmitz, C., Kuske, M., Yiallouros, I., Floehr, J., Jahnen-Dechent, W., Stocker, W.
Deposit date:2019-07-18
Release date:2019-10-23
Method:X-RAY DIFFRACTION (3 Å)
Cite:The C-terminal region of human plasma fetuin-B is dispensable for the raised-elephant-trunk mechanism of inhibition of astacin metallopeptidases.
Sci Rep, 9, 2019
6I9A
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PORPHYROMONAS GINGIVALIS GINGIPAIN K (KGP) IN COMPLEX WITH INHIBITOR KYT-36
Descriptor:Lys-gingipain W83, UNKNOWN ATOM OR ION, SODIUM ION, ...
Authors:Gomis-Ruth, F.X., Guevara, T., Rofdriguez-Banqueri, A.
Deposit date:2018-11-22
Release date:2019-03-13
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural determinants of inhibition of Porphyromonas gingivalis gingipain K by KYT-36, a potent, selective, and bioavailable peptidase inhibitor.
Sci Rep, 9, 2019
6HT9
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MOUSE FETUIN-B IN COMPLEX WITH CRAYFISH ASTACIN
Descriptor:Astacin, Fetuin-B, ZINC ION, ...
Authors:Gomis-Ruth, F.X., Goulas, T., Guevara, T., Cuppari, A.
Deposit date:2018-10-03
Release date:2019-03-13
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of mammalian plasma fetuin-B and its mechanism of selective metallopeptidase inhibition.
Iucrj, 6, 2019
6I9J
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HUMAN TRANSFORMING GROWTH FACTOR BETA2 IN A TETRAGONAL CRYSTAL FORM
Descriptor:Transforming growth factor beta-2 proprotein
Authors:Gomis-Ruth, F.X., Marino-Puertas, L., del Amo-Maestro, L., Goulas, T.
Deposit date:2018-11-23
Release date:2019-07-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Recombinant production, purification, crystallization, and structure analysis of human transforming growth factor beta 2 in a new conformation.
Sci Rep, 9, 2019
6I0X
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PORPHYROMONAS GINGIVALIS PEPTIDYLARGININE DEMINASE (PPAD) MUTANT G231N/E232T/N235D IN COMPLEX WITH CL-AMIDINE.
Descriptor:Peptidylarginine deiminase, SODIUM ION, N-[(1S)-1-(AMINOCARBONYL)-4-(ETHANIMIDOYLAMINO)BUTYL]BENZAMIDE, ...
Authors:Gomis-Ruth, F.X., Goulas, T., Sola, M., Potempa, J.
Deposit date:2018-10-26
Release date:2019-01-23
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure, function, and inhibition of a genomic/clinical variant of Porphyromonas gingivalis peptidylarginine deiminase.
Protein Sci., 28, 2019
3OSL
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STRUCTURE OF BOVINE THROMBIN-ACTIVATABLE FIBRINOLYSIS INHIBITOR IN COMPLEX WITH TICK CARBOXYPEPTIDASE INHIBITOR
Descriptor:Carboxypeptidase B2, Carboxypeptidase inhibitor, ZINC ION
Authors:Valnickova, Z., Sanglas, L., Arolas, J.L., Petersen, S.V., Schar, C., Otzen, D., Aviles, F.X., Gomis-Ruth, F.X., Enghild, J.J.
Deposit date:2010-09-09
Release date:2010-09-29
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (6 Å)
Cite:Flexibility of the Thrombin-activatable Fibrinolysis Inhibitor Pro-domain Enables Productive Binding of Protein Substrates.
J.Biol.Chem., 285, 2010
2BOA
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HUMAN PROCARBOXYPEPTIDASE A4.
Descriptor:CARBOXYPEPTIDASE A4, N-ACETYL-D-GLUCOSAMINE, ZINC ION, ...
Authors:Garcia-Castellanos, R., Bonet-Figueredo, R., Pallares, I., Ventura, S., Aviles, F.X., Vendrell, J., Gomis-Ruth, F.X.
Deposit date:2005-04-08
Release date:2005-12-13
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Detailed Molecular Comparison between the Inhibition Mode of A/B-Type Carboxypeptidases in the Zymogen State and by the Endogenous Inhibitor Latexin.
Cell.Mol.Life Sci., 62, 2005
2PCU
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HUMAN CARBOXYPEPTIDASE A4 IN COMPLEX WITH A CLEAVED HEXAPEPTIDE.
Descriptor:Carboxypeptidase A4, peptide, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Bayes, A., Fernandez, D., Sola, M., Marrero, A., Garcia-Pique, S., Aviles, F.X., Vendrell, J., Gomis-Ruth, F.X.
Deposit date:2007-03-30
Release date:2007-04-17
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Caught after the Act: a human A-type metallocarboxypeptidase in a product complex with a cleaved hexapeptide.
Biochemistry, 46, 2007
3D4U
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BOVINE THROMBIN-ACTIVATABLE FIBRINOLYSIS INHIBITOR (TAFIA) IN COMPLEX WITH TICK-DERIVED CARBOXYPEPTIDASE INHIBITOR.
Descriptor:Carboxypeptidase B2, Carboxypeptidase inhibitor, ZINC ION, ...
Authors:Sanglas, L., Valnickova, Z., Arolas, J.L., Pallares, I., Guevara, T., Sola, M., Kristensen, T., Enghild, J.J., Aviles, F.X., Gomis-Ruth, F.X.
Deposit date:2008-05-15
Release date:2008-08-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of activated thrombin-activatable fibrinolysis inhibitor, a molecular link between coagulation and fibrinolysis.
Mol.Cell, 31, 2008
3DWC
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TRYPANOSOMA CRUZI METALLOCARBOXYPEPTIDASE 1
Descriptor:Metallocarboxypeptidase, COBALT (II) ION, SULFATE ION, ...
Authors:Niemirowicz, G., Fernandez, D., Sola, M., Cazzulo, J.J., Aviles, F.X., Gomis-Ruth, F.X.
Deposit date:2008-07-22
Release date:2008-09-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The molecular analysis of Trypanosoma cruzi metallocarboxypeptidase 1 provides insight into fold and substrate specificity
Mol.Microbiol., 70, 2008
3FJU
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ASCARIS SUUM CARBOXYPEPTIDASE INHIBITOR IN COMPLEX WITH HUMAN CARBOXYPEPTIDASE A1
Descriptor:Carboxypeptidase A1, Carboxypeptidase A inhibitor, ZINC ION, ...
Authors:Sanglas, L., Aviles, F.X., Huber, R., Gomis-Ruth, F.X., Arolas, J.L.
Deposit date:2008-12-15
Release date:2008-12-30
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Mammalian metallopeptidase inhibition at the defense barrier of Ascaris parasite
Proc.Natl.Acad.Sci.USA, 106, 2009
3LMS
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STRUCTURE OF HUMAN ACTIVATED THROMBIN-ACTIVATABLE FIBRINOLYSIS INHIBITOR, TAFIA, IN COMPLEX WITH TICK-DERIVED FUNNELIN INHIBITOR, TCI.
Descriptor:Carboxypeptidase B2, Carboxypeptidase inhibitor, ZINC ION, ...
Authors:Sanglas, L., Arolas, J.L., Valnickova, Z., Aviles, F.X., Enghild, J.J., Gomis-Ruth, F.X.
Deposit date:2010-02-01
Release date:2010-02-16
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Insights into the molecular inactivation mechanism of human activated thrombin-activatable fibrinolysis inhibitor
J.Thromb.Haemost., 8, 2010
3MN8
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STRUCTURE OF DROSOPHILA MELANOGASTER CARBOXYPEPTIDASE D ISOFORM 1B SHORT
Descriptor:LP15968p, N-ACETYL-D-GLUCOSAMINE, ZINC ION, ...
Authors:Tanco, S., Arolas, J.L., Guevara, T., Lorenzo, J., Aviles, F.X., Gomis-Ruth, F.X.
Deposit date:2010-04-21
Release date:2010-07-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure-Function Analysis of the Short Splicing Variant Carboxypeptidase Encoded by Drosophila melanogaster silver.
J.Mol.Biol., 401, 2010
1AZW
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PROLINE IMINOPEPTIDASE FROM XANTHOMONAS CAMPESTRIS PV. CITRI
Descriptor:PROLINE IMINOPEPTIDASE
Authors:Medrano, F.J., Alonso, J., Garcia, J.L., Romero, A., Bode, W., Gomis-Ruth, F.X.
Deposit date:1997-11-22
Release date:1999-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of proline iminopeptidase from Xanthomonas campestris pv. citri: a prototype for the prolyl oligopeptidase family.
EMBO J., 17, 1998
1OMH
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CONJUGATIVE RELAXASE TRWC IN COMPLEX WITH ORIT DNA. METAL-FREE STRUCTURE.
Descriptor:DNA OLIGONUCLEOTIDE, trwC protein, SULFATE ION
Authors:Guasch, A., Lucas, M., Moncalian, G., Cabezas, M., Perez-Luque, R., Gomis-Ruth, F.X., de la Cruz, F., Coll, M.
Deposit date:2003-02-25
Release date:2003-11-25
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Recognition and processing of the origin of transfer DNA by conjugative relaxase TrwC.
Nat.Struct.Biol., 10, 2003
1OSB
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CONJUGATIVE RELAXASE TRWC IN COMPLEX WITH ORIT DNA. METAL-FREE STRUCTURE.
Descriptor:Dna oligonucleotide, TrwC protein, SULFATE ION
Authors:Guasch, A., Lucas, M., Moncalian, G., Cabezas, M., Perez-Luque, R., Gomis-Ruth, F.X., de la Cruz, F., Coll, M.
Deposit date:2003-03-19
Release date:2003-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Recognition and processing of the origin of transfer DNA by conjugative relaxase TrwC.
Nat.Struct.Biol., 10, 2003
2J83
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ULILYSIN METALLOPROTEASE IN COMPLEX WITH BATIMASTAT.
Descriptor:ULILYSIN, 4-(N-HYDROXYAMINO)-2R-ISOBUTYL-2S-(2-THIENYLTHIOMETHYL)SUCCINYL-L-PHENYLALANINE-N-METHYLAMIDE, CALCIUM ION, ...
Authors:Garcia-Castellanos, R., Tallant, C., Marrero, A., Sola, M., Baumann, U., Gomis-Ruth, F.X.
Deposit date:2006-10-18
Release date:2006-12-19
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Substrate Specificity of a Metalloprotease of the Pappalysin Family Revealed by an Inhibitor and a Product Complex.
Arch.Biochem.Biophys., 457, 2007