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4EIP
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BU of 4eip by Molmil
Native and K252c bound RebC-10x
Descriptor: 6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one, FLAVIN-ADENINE DINUCLEOTIDE, Putative FAD-monooxygenase
Authors:Goldman, P.J, Ryan, K.S, Howard-Jones, A.R, Hamill, M.J, Elliott, S.J, Walsh, C.T, Drennan, C.L.
Deposit date:2012-04-05
Release date:2012-08-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.332 Å)
Cite:An Unusual Role for a Mobile Flavin in StaC-like Indolocarbazole Biosynthetic Enzymes.
Chem.Biol., 19, 2012
4EIQ
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BU of 4eiq by Molmil
Chromopyrrolic acid-soaked RebC-10x with bound 7-carboxy-K252c
Descriptor: (5S)-7-oxo-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5-carboxylic acid, Putative FAD-monooxygenase
Authors:Goldman, P.J, Ryan, K.S, Howard-Jones, A.R, Hamill, M.J, Elliott, S.J, Walsh, C.T, Drennan, C.L.
Deposit date:2012-04-05
Release date:2012-08-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:An Unusual Role for a Mobile Flavin in StaC-like Indolocarbazole Biosynthetic Enzymes.
Chem.Biol., 19, 2012
4K39
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BU of 4k39 by Molmil
Native anSMEcpe with bound AdoMet and Cp18Cys peptide
Descriptor: Anaerobic sulfatase-maturating enzyme, CHLORIDE ION, Cp18Cys peptide, ...
Authors:Goldman, P.J, Drennan, C.L.
Deposit date:2013-04-10
Release date:2013-05-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.783 Å)
Cite:X-ray structure of an AdoMet radical activase reveals an anaerobic solution for formylglycine posttranslational modification.
Proc.Natl.Acad.Sci.USA, 110, 2013
4M7S
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BU of 4m7s by Molmil
Crystal structure of SeMet BtrN in an OPEN conformation
Descriptor: BtrN, GLYCEROL, IMIDAZOLE, ...
Authors:Goldman, P.J, Drennan, C.L.
Deposit date:2013-08-12
Release date:2013-10-02
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (2.022 Å)
Cite:X-ray analysis of butirosin biosynthetic enzyme BtrN redefines structural motifs for AdoMet radical chemistry.
Proc.Natl.Acad.Sci.USA, 110, 2013
4K38
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BU of 4k38 by Molmil
Native anSMEcpe with bound AdoMet and Kp18Cys peptide
Descriptor: Anaerobic sulfatase-maturating enzyme, CHLORIDE ION, GLYCEROL, ...
Authors:Goldman, P.J, Drennan, C.L.
Deposit date:2013-04-10
Release date:2013-05-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.831 Å)
Cite:X-ray structure of an AdoMet radical activase reveals an anaerobic solution for formylglycine posttranslational modification.
Proc.Natl.Acad.Sci.USA, 110, 2013
4K37
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BU of 4k37 by Molmil
Native anSMEcpe with bound AdoMet
Descriptor: Anaerobic sulfatase-maturating enzyme, CHLORIDE ION, GLYCEROL, ...
Authors:Goldman, P.J, Drennan, C.L.
Deposit date:2013-04-10
Release date:2013-05-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:X-ray structure of an AdoMet radical activase reveals an anaerobic solution for formylglycine posttranslational modification.
Proc.Natl.Acad.Sci.USA, 110, 2013
4K36
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BU of 4k36 by Molmil
His6 tagged anSMEcpe with bound AdoMet
Descriptor: Anaerobic sulfatase-maturating enzyme, CHLORIDE ION, IRON/SULFUR CLUSTER, ...
Authors:Goldman, P.J, Drennan, C.L.
Deposit date:2013-04-10
Release date:2013-05-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.619 Å)
Cite:X-ray structure of an AdoMet radical activase reveals an anaerobic solution for formylglycine posttranslational modification.
Proc.Natl.Acad.Sci.USA, 110, 2013
4TVY
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BU of 4tvy by Molmil
Apo resorufin ligase
Descriptor: 5-(3,7-dihydroxy-10H-phenoxazin-2-yl)pentanamide, Lipoate-protein ligase A
Authors:Goldman, P.J, Drennan, C.L.
Deposit date:2014-06-28
Release date:2014-10-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.151 Å)
Cite:Computational design of a red fluorophore ligase for site-specific protein labeling in living cells.
Proc.Natl.Acad.Sci.USA, 111, 2014
4TVW
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BU of 4tvw by Molmil
Resorufin ligase with bound resorufin-AMP analog
Descriptor: 5'-O-{[5-(7-hydroxy-3-oxo-3H-phenoxazin-2-yl)pentanoyl]sulfamoyl}adenosine, Lipoate-protein ligase A
Authors:Goldman, P.J, Drennan, C.L.
Deposit date:2014-06-28
Release date:2014-10-22
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.505 Å)
Cite:Computational design of a red fluorophore ligase for site-specific protein labeling in living cells.
Proc.Natl.Acad.Sci.USA, 111, 2014
4M7T
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BU of 4m7t by Molmil
Crystal structure of BtrN in complex with AdoMet and 2-DOIA
Descriptor: (1R,2S,3S,4R,5S)-5-aminocyclohexane-1,2,3,4-tetrol, BtrN, GLYCEROL, ...
Authors:Drennan, C.L, Goldman, P.J.
Deposit date:2013-08-12
Release date:2013-10-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:X-ray analysis of butirosin biosynthetic enzyme BtrN redefines structural motifs for AdoMet radical chemistry.
Proc.Natl.Acad.Sci.USA, 110, 2013
5EXJ
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BU of 5exj by Molmil
Crystal structure of M. tuberculosis lipoyl synthase at 1.64 A resolution
Descriptor: (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, IRON/SULFUR CLUSTER, Lipoyl synthase
Authors:McLaughlin, M.I, Lanz, N.D, Goldman, P.J, Lee, K.-H, Booker, S.J, Drennan, C.L.
Deposit date:2015-11-23
Release date:2016-08-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Crystallographic snapshots of sulfur insertion by lipoyl synthase.
Proc.Natl.Acad.Sci.USA, 113, 2016
5EXI
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BU of 5exi by Molmil
Crystal structure of M. tuberculosis lipoyl synthase at 2.28 A resolution
Descriptor: (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, IRON/SULFUR CLUSTER, Lipoyl synthase
Authors:McLaughlin, M.I, Lanz, N.D, Goldman, P.J, Lee, K.-H, Booker, S.J, Drennan, C.L.
Deposit date:2015-11-23
Release date:2016-08-10
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Crystallographic snapshots of sulfur insertion by lipoyl synthase.
Proc.Natl.Acad.Sci.USA, 113, 2016
5EXK
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BU of 5exk by Molmil
Crystal structure of M. tuberculosis lipoyl synthase with 6-thiooctanoyl peptide intermediate
Descriptor: 5'-DEOXYADENOSINE, CHLORIDE ION, FE3-S4 CLUSTER, ...
Authors:McLaughlin, M.I, Lanz, N.D, Goldman, P.J, Lee, K.-H, Booker, S.J, Drennan, C.L.
Deposit date:2015-11-23
Release date:2016-08-10
Last modified:2019-11-27
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Crystallographic snapshots of sulfur insertion by lipoyl synthase.
Proc.Natl.Acad.Sci.USA, 113, 2016

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