Author results

1GRZ
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A PREORGANIZED ACTIVE SITE IN THE CRYSTAL STRUCTURE OF THE TETRAHYMENA RIBOZYME
Descriptor:LSU R-RNA GROUP I INTRON
Authors:Golden, B.L., Gooding, A.R., Podell, E.R., Cech, T.R.
Deposit date:1998-09-14
Release date:1998-11-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (5 Å)
Cite:A preorganized active site in the crystal structure of the Tetrahymena ribozyme.
Science, 282, 1998
1RL6
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RIBOSOMAL PROTEIN L6
Descriptor:PROTEIN (RIBOSOMAL PROTEIN L6)
Authors:Golden, B.L., Davies, C., Ramakrishnan, V., White, S.W.
Deposit date:1999-01-14
Release date:1999-02-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Ribosomal protein L6: structural evidence of gene duplication from a primitive RNA binding protein.
EMBO J., 12, 1993
1RIP
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RIBOSOMAL PROTEIN S17: CHARACTERIZATION OF THE THREE-DIMENSIONAL STRUCTURE BY 1H-AND 15N-NMR
Descriptor:RIBOSOMAL PROTEIN S17
Authors:Golden, B.L., Hoffman, D.W., Ramakrishnan, V., White, S.W.
Deposit date:1993-08-17
Release date:1993-10-31
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Ribosomal protein S17: characterization of the three-dimensional structure by 1H and 15N NMR.
Biochemistry, 32, 1993
1Y0Q
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CRYSTAL STRUCTURE OF AN ACTIVE GROUP I RIBOZYME-PRODUCT COMPLEX
Descriptor:Group I ribozyme, 5'-R(*GP*CP*UP*U)-3', SPERMINE (FULLY PROTONATED FORM), ...
Authors:Golden, B.L., Kim, H., Chase, E.
Deposit date:2004-11-16
Release date:2004-12-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Crystal structure of a phage Twort group I ribozyme-product complex
Nat.Struct.Mol.Biol., 12, 2005
1GID
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CRYSTAL STRUCTURE OF A GROUP I RIBOZYME DOMAIN: PRINCIPLES OF RNA PACKING
Descriptor:P4-P6 RNA RIBOZYME DOMAIN, MAGNESIUM ION, COBALT HEXAMMINE(III)
Authors:Cate, J.H., Gooding, A.R., Podell, E., Zhou, K., Golden, B.L., Kundrot, C.E., Cech, T.R., Doudna, J.A.
Deposit date:1996-08-22
Release date:1996-12-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a group I ribozyme domain: principles of RNA packing.
Science, 273, 1996
5EAO
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TWO ACTIVE SITE DIVALENT ION IN THE CRYSTAL STRUCTURE OF THE HAMMERHEAD RIBOZYME BOUND TO A TRANSITION STATE ANALOG-MG2+
Descriptor:RNA (48-MER), RNA (5'-R(*GP*GP*GP*CP*GP*U*(CVC)*UP*GP*GP*GP*CP*AP*GP*UP*AP*CP*CP*CP*A)-3'), MAGNESIUM ION
Authors:Mir, A., Golden, B.L.
Deposit date:2015-10-16
Release date:2016-02-24
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.988 Å)
Cite:Two Active Site Divalent Ions in the Crystal Structure of the Hammerhead Ribozyme Bound to a Transition State Analogue.
Biochemistry, 55, 2016
5EAQ
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TWO ACTIVE SITE DIVALENT ION IN THE CRYSTAL STRUCTURE OF THE HAMMERHEAD RIBOZYME BOUND TO A TRANSITION STATE ANALOG-MN2+
Descriptor:RNA (48-MER), RNA (5'-R(*GP*GP*GP*CP*GP*U*(CVC)*UP*GP*GP*GP*CP*AP*GP*UP*AP*CP*CP*CP*A)-3'), MANGANESE (II) ION
Authors:Mir, A., Golden, B.L.
Deposit date:2015-10-16
Release date:2016-02-24
Method:X-RAY DIFFRACTION (3.201 Å)
Cite:Two Active Site Divalent Ions in the Crystal Structure of the Hammerhead Ribozyme Bound to a Transition State Analogue.
Biochemistry, 55, 2016
2RKJ
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COCRYSTAL STRUCTURE OF A TYROSYL-TRNA SYNTHETASE SPLICING FACTOR WITH A GROUP I INTRON RNA
Descriptor:RNA (238-MER), RNA (5'-R(P*GP*CP*UP*U)-3'), Tyrosyl-tRNA synthetase
Authors:Paukstelis, P.J., Chen, J.-H., Chase, E., Lambowitz, A.M., Golden, B.L.
Deposit date:2007-10-16
Release date:2008-01-08
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Structure of a tyrosyl-tRNA synthetase splicing factor bound to a group I intron RNA.
Nature, 451, 2008
3MJ3
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CRICKET PARALYSIS VIRUS IGR IRES DOMAIN 3 RNA BOUND TO SELENATE
Descriptor:Domain 3 of the cricket paralysis virus intergenic region IRES RNA, RNA (5'-R(P*UP*AP*AP*GP*AP*AP*AP*UP*UP*UP*AP*CP*CP*U)-3'), SELENATE ION
Authors:Kieft, J.S., Chase, E., Costantino, D.A., Golden, B.L.
Deposit date:2010-04-12
Release date:2010-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Identification and characterization of anion binding sites in RNA.
Rna, 16, 2010
3MJA
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CRICKET PARALYSIS VIRUS IGR IRES DOMAIN 3 RNA BOUND TO SELENATE, STRUCTURE #2
Descriptor:Domain 3 of the cricket paralysis virus intergenic region IRES RNA, RNA (5'-R(P*UP*AP*AP*GP*AP*AP*AP*UP*UP*UP*AP*CP*CP*U)-3'), SELENATE ION
Authors:Kieft, J.S., Golden, B.L., Costantino, D.A., Chase, E.
Deposit date:2010-04-12
Release date:2010-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Identification and characterization of anion binding sites in RNA.
Rna, 16, 2010
3MJB
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CRICKET PARALYSIS VIRUS IGR IRES DOMAIN 3 RNA BOUND TO SULFATE
Descriptor:Domain 3 of the cricket paralysis virus intergenic region IRES RNA, RNA (5'-R(P*UP*AP*AP*GP*AP*AP*AP*UP*UP*UP*AP*CP*CP*U)-3'), SULFATE ION
Authors:Kieft, J.S., Golden, B.L., Costantino, D.A., Chase, E.
Deposit date:2010-04-12
Release date:2010-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Identification and characterization of anion binding sites in RNA.
Rna, 16, 2010
3NKB
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A 1.9A CRYSTAL STRUCTURE OF THE HDV RIBOZYME PRECLEAVAGE SUGGESTS BOTH LEWIS ACID AND GENERAL ACID MECHANISMS CONTRIBUTE TO PHOSPHODIESTER CLEAVAGE
Descriptor:DNA/RNA (5'-D(*(DUR))-D(*GP*G)-R(P*CP*UP*UP*GP*CP*A)-3'), The hepatitis delta virus ribozyme, MAGNESIUM ION
Authors:Chen, J.-H., Yajima, R., Chadalavada, D.M., Chase, E., Bevilacqua, P.C., Golden, B.L.
Deposit date:2010-06-18
Release date:2010-09-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.916 Å)
Cite:A 1.9 A crystal structure of the HDV ribozyme precleavage suggests both Lewis acid and general acid mechanisms contribute to phosphodiester cleavage.
Biochemistry, 49, 2010
3OOL
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I-SCEI COMPLEXED WITH C/G+4 DNA SUBSTRATE
Descriptor:Intron encoded endonuclease I-SceI, 5'-D(*CP*AP*CP*GP*CP*TP*AP*GP*GP*GP*AP*TP*AP*AP*CP*CP*GP*GP*GP*TP*AP*AP*TP*AP*C)-3', 5'-D(*GP*GP*TP*AP*TP*TP*AP*CP*CP*CP*GP*GP*TP*TP*AP*TP*CP*CP*CP*TP*AP*GP*CP*GP*T)-3', ...
Authors:Joshi, R., Chen, J.-H., Golden, B.L., Gimble, F.S.
Deposit date:2010-08-31
Release date:2010-11-17
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Evolution of I-SceI Homing Endonucleases with Increased DNA Recognition Site Specificity.
J.Mol.Biol., 405, 2011
3OOR
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I-SCEI MUTANT (K86R/G100T)COMPLEXED WITH C/G+4 DNA SUBSTRATE
Descriptor:Intron encoded endonuclease I-SceI, 5'-D(*CP*AP*CP*GP*CP*TP*AP*GP*GP*GP*AP*TP*AP*AP*CP*CP*GP*GP*GP*TP*AP*AP*TP*AP*C)-3', 5'-D(*GP*GP*TP*AP*TP*TP*AP*CP*CP*CP*GP*GP*TP*TP*AP*TP*CP*CP*CP*TP*AP*GP*CP*GP*T)-3', ...
Authors:Joshi, R., Chen, J.-H., Golden, B.L., Gimble, F.S.
Deposit date:2010-08-31
Release date:2010-11-17
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Evolution of I-SceI Homing Endonucleases with Increased DNA Recognition Site Specificity.
J.Mol.Biol., 405, 2011
5DH6
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TWO DIVALENT METAL IONS AND CONFORMATIONAL CHANGES PLAY ROLES IN THE HAMMERHEAD RIBOZYME CLEAVAGE REACTION-G12A MUTANT IN MG2+
Descriptor:hammerhead ribozyme, 5'-R(*GP*GP*GP*CP*GP*U)-D(P*C)-R(P*UP*GP*GP*GP*CP*AP*GP*UP*AP*CP*CP*CP*A)-3', MAGNESIUM ION
Authors:Mir, A., Chen, J., Neau, D., Golden, B.L.
Deposit date:2015-08-29
Release date:2015-10-07
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.784 Å)
Cite:Two Divalent Metal Ions and Conformational Changes Play Roles in the Hammerhead Ribozyme Cleavage Reaction.
Biochemistry, 54, 2015
5DH7
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TWO DIVALENT METAL IONS AND CONFORMATIONAL CHANGES PLAY ROLES IN THE HAMMERHEAD RIBOZYME CLEAVAGE REACTION-G12A MUTANT IN MN2+
Descriptor:RNA (48-MER), 5'-R(*GP*GP*GP*CP*GP*UP*DC*UP*GP*GP*GP*CP*AP*GP*UP*AP*CP*CP*CP*A)-3', MANGANESE (II) ION
Authors:Mir, A., Chen, J., Neau, D., Golden, B.L.
Deposit date:2015-08-29
Release date:2015-10-07
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3.064 Å)
Cite:Two Divalent Metal Ions and Conformational Changes Play Roles in the Hammerhead Ribozyme Cleavage Reaction.
Biochemistry, 54, 2015
5DH8
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TWO DIVALENT METAL IONS AND CONFORMATIONAL CHANGES PLAY ROLES IN THE HAMMERHEAD RIBOZYME CLEAVAGE REACTION- G12A MUTANT IN ZN2+
Descriptor:RNA (48-MER), 5'-R(*GP*GP*GP*CP*GP*U)-D(P*C)-R(P*UP*GP*GP*GP*CP*AP*GP*UP*AP*CP*CP*CP*A)-3', ZINC ION
Authors:Mir, A., Chen, J., Neau, D., Golden, B.L.
Deposit date:2015-08-29
Release date:2015-10-07
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3.297 Å)
Cite:Two Divalent Metal Ions and Conformational Changes Play Roles in the Hammerhead Ribozyme Cleavage Reaction.
Biochemistry, 54, 2015
5DI2
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TWO DIVALENT METAL IONS AND CONFORMATIONAL CHANGES PLAY ROLES IN THE HAMMERHEAD RIBOZYME CLEAVAGE REACTION-WT RIBOZYME IN MN2+ AT HIGH PH
Descriptor:RNA (48-MER), 5'-R(*GP*GP*GP*CP*GP*U)-D(P*C)-R(P*UP*GP*GP*GP*CP*AP*GP*UP*AP*CP*CP*CP*A)-3', MANGANESE (II) ION
Authors:Mir, A., Chen, J., Neau, D., Golden, B.L.
Deposit date:2015-08-31
Release date:2015-10-07
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.989 Å)
Cite:Two Divalent Metal Ions and Conformational Changes Play Roles in the Hammerhead Ribozyme Cleavage Reaction.
Biochemistry, 54, 2015
5DI4
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TWO DIVALENT METAL IONS AND CONFORMATIONAL CHANGES PLAY ROLES IN THE HAMMERHEAD RIBOZYME CLEAVAGE REACTION-WT RIBOZYME IN MN2+ AT LOW PH
Descriptor:RNA (48-MER), 5'-R(*GP*GP*GP*CP*GP*U)-D(P*C)-R(P*UP*GP*GP*GP*CP*AP*GP*UP*AP*CP*CP*CP*A)-3', MANGANESE (II) ION
Authors:Mir, A., Chen, J., Neau, D., Golden, B.L.
Deposit date:2015-08-31
Release date:2015-10-07
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.948 Å)
Cite:Two Divalent Metal Ions and Conformational Changes Play Roles in the Hammerhead Ribozyme Cleavage Reaction.
Biochemistry, 54, 2015
5DQK
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TWO DIVALENT METAL IONS AND CONFORMATIONAL CHANGES PLAY ROLES IN THE HAMMERHEAD RIBOZYME CLEAVAGE REACTION-WT RIBOZYME IN MG2+
Descriptor:RNA (48-MER), RNA (5'-R(*GP*GP*GP*CP*GP*U)-D(P*C)-R(P*UP*GP*GP*GP*CP*AP*GP*UP*AP*CP*CP*CP*A)-3'), MAGNESIUM ION, ...
Authors:Mir, A., Chen, J., Neau, D., Golden, B.L.
Deposit date:2015-09-14
Release date:2015-10-07
Last modified:2015-11-04
Method:X-RAY DIFFRACTION (2.707 Å)
Cite:Two Divalent Metal Ions and Conformational Changes Play Roles in the Hammerhead Ribozyme Cleavage Reaction.
Biochemistry, 54, 2015
1DIV
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RIBOSOMAL PROTEIN L9
Descriptor:RIBOSOMAL PROTEIN L9
Authors:Hoffman, D.W., Cameron, C., Davies, C., Gerchman, S.E., Kycia, J.H., Porter, S., Ramakrishnan, V., White, S.W.
Deposit date:1996-07-02
Release date:1997-01-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of prokaryotic ribosomal protein L9: a bi-lobed RNA-binding protein.
EMBO J., 13, 1994
1EG0
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FITTING OF COMPONENTS WITH KNOWN STRUCTURE INTO AN 11.5 A CRYO-EM MAP OF THE E.COLI 70S RIBOSOME
Descriptor:FRAGMENT OF 16S RRNA HELIX 23, FRAGMENT OF 23S RRNA, HELIX 95 OF 23S RRNA, ...
Authors:Gabashvili, I.S., Agrawal, R.K., Spahn, C.M.T., Grassucci, R.A., Svergun, D.I., Frank, J., Penczek, P.
Deposit date:2000-02-11
Release date:2000-03-06
Last modified:2011-07-13
Method:ELECTRON MICROSCOPY (11.5 Å)
Cite:Solution structure of the E. coli 70S ribosome at 11.5 A resolution.
Cell(Cambridge,Mass.), 100, 2000
1HR2
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CRYSTAL STRUCTURE ANALYSIS OF A MUTANT P4-P6 DOMAIN (DELC209) OF TETRAHYMENA THEMOPHILA GROUP I INTRON.
Descriptor:P4-P6 DELC209 MUTANT RNA RIBOZYME DOMAIN, MAGNESIUM ION
Authors:Juneau, K., Podell, E.R., Harrington, D.J., Cech, T.R.
Deposit date:2000-12-20
Release date:2001-04-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis of the enhanced stability of a mutant ribozyme domain and a detailed view of RNA--solvent interactions.
Structure, 9, 2001
376D
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A ZIPPER-LIKE DNA DUPLEX D(GCGAAAGCT)
Descriptor:DNA (5'-D(*GP*(CBR)P*GP*AP*AP*AP*GP*CP*T)-3'), COBALT HEXAMMINE(III)
Authors:Cruse, W.B.T., Shepard, W., Prange, T., delalFortelle, E., Fourme, R.
Deposit date:1998-01-22
Release date:1999-10-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A zipper-like duplex in DNA: the crystal structure of d(GCGAAAGCT) at 2.1 A resolution.
Structure, 6, 1998
487D
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SEVEN RIBOSOMAL PROTEINS FITTED TO A CRYO-ELECTRON MICROSCOPIC MAP OF THE LARGE 50S SUBUNIT AT 7.5 ANGSTROMS RESOLUTION
Descriptor:PROTEIN (50S L1 RIBOSOMAL PROTEIN), PROTEIN (50S L2 RIBOSOMAL PROTEIN), PROTEIN (50S L6 RIBOSOMAL PROTEIN), ...
Authors:Brimacombe, R., Mueller, F.
Deposit date:2000-02-23
Release date:2000-04-10
Last modified:2011-07-13
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:The 3D arrangement of the 23 S and 5 S rRNA in the Escherichia coli 50 S ribosomal subunit based on a cryo-electron microscopic reconstruction at 7.5 A resolution.
J.Mol.Biol., 298, 2000