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5N5C
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BU of 5n5c by Molmil
NMR solution structure of the TSL2 RNA hairpin
Descriptor: RNA (19-MER)
Authors:Garcia-Lopez, A, Wacker, A, Tessaro, F, Jonker, H.R.A, Richter, C, Comte, A, Berntenis, N, Schmucki, R, Hatje, K, Sciarra, D, Konieczny, P, Fournet, G, Faustino, I, Orozco, M, Artero, R, Goekjian, P, Metzger, F, Ebeling, M, Joseph, B, Schwalbe, H, Scapozza, L.
Deposit date:2017-02-13
Release date:2018-03-14
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Targeting RNA structure in SMN2 reverses spinal muscular atrophy molecular phenotypes.
Nat Commun, 9, 2018
8ARJ
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BU of 8arj by Molmil
Anaplastic Lymphoma Kinase with a novel carboline inhibitor
Descriptor: 3-(dimethylamino)-1-[3-[4-(4-methylpiperazin-1-yl)phenyl]-9~{H}-pyrido[2,3-b]indol-6-yl]prop-2-en-1-one, ALK tyrosine kinase receptor
Authors:Mologni, L, Scapozza, L, Gambacorti-Passerini, C, Tardy, S, Goekjian, P, Robinson, C, Brown, D.
Deposit date:2022-08-17
Release date:2022-09-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.645 Å)
Cite:Discovery of Novel alpha-Carboline Inhibitors of the Anaplastic Lymphoma Kinase.
Acs Omega, 7, 2022

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