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8TKP
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BU of 8tkp by Molmil
Structure of the C. elegans TMC-2 complex
Descriptor: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Clark, S, Jeong, H, Goehring, A, Posert, R, Gouaux, E.
Deposit date:2023-07-25
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:The structure of the Caenorhabditis elegans TMC-2 complex suggests roles of lipid-mediated subunit contacts in mechanosensory transduction.
Proc.Natl.Acad.Sci.USA, 121, 2024
5UP2
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BU of 5up2 by Molmil
Triheteromeric NMDA receptor GluN1/GluN2A/GluN2B in complex with glycine, glutamate, Ro 25-6981, MK-801 and a GluN2B-specific Fab, at pH 6.5
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GluN2B-specific Fab, ...
Authors:Lu, W, Du, J, Goehring, A, Gouaux, E.
Deposit date:2017-02-01
Release date:2017-03-22
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Cryo-EM structures of the triheteromeric NMDA receptor and its allosteric modulation.
Science, 355, 2017
5UOW
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BU of 5uow by Molmil
Triheteromeric NMDA receptor GluN1/GluN2A/GluN2B in complex with glycine, glutamate, MK-801 and a GluN2B-specific Fab, at pH 6.5
Descriptor: (5S,10R)-5-methyl-10,11-dihydro-5H-5,10-epiminodibenzo[a,d][7]annulene, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ...
Authors:Lu, W, Du, J, Goehring, A, Gouaux, E.
Deposit date:2017-02-01
Release date:2017-03-22
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Cryo-EM structures of the triheteromeric NMDA receptor and its allosteric modulation.
Science, 355, 2017
5IOU
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BU of 5iou by Molmil
Cryo-EM structure of GluN1/GluN2B NMDA receptor in the glutamate/glycine-bound conformation
Descriptor: GLUTAMIC ACID, GLYCINE, Ionotropic glutamate receptor subunit NR2B, ...
Authors:Zhu, S, Stein, A.R, Yoshioka, C, Lee, C.H, Goehring, A, Mchaourab, S.H, Gouaux, E.
Deposit date:2016-03-09
Release date:2016-04-20
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (7 Å)
Cite:Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016
5IPU
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BU of 5ipu by Molmil
Cryo-EM structure of GluN1/GluN2B NMDA receptor in the DCKA/D-APV-bound conformation, state 6
Descriptor: Ionotropic glutamate receptor subunit NR2B, N-methyl-D-aspartate receptor subunit NR1-8a
Authors:Zhu, S, Stein, A.R, Yoshioka, C, Lee, C.H, Goehring, A, Mchaourab, S.H, Gouaux, E.
Deposit date:2016-03-09
Release date:2016-04-20
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (15.4 Å)
Cite:Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016
5IPT
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BU of 5ipt by Molmil
Cryo-EM structure of GluN1/GluN2B NMDA receptor in the DCKA/D-APV-bound conformation, state 5
Descriptor: Ionotropic glutamate receptor subunit NR2B, N-methyl-D-aspartate receptor subunit NR1-8a
Authors:Zhu, S, Stein, A.R, Yoshioka, C, Lee, C.H, Goehring, A, Mchaourab, S.H, Gouaux, E.
Deposit date:2016-03-09
Release date:2016-04-20
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (14.1 Å)
Cite:Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016
5IPS
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BU of 5ips by Molmil
Cryo-EM structure of GluN1/GluN2B NMDA receptor in the DCKA/D-APV-bound conformation, state 4
Descriptor: Ionotropic glutamate receptor subunit NR2B, N-methyl-D-aspartate receptor subunit NR1-8a
Authors:Zhu, S, Stein, A.R, Yoshioka, C, Lee, C.H, Goehring, A, Mchaourab, S.H, Gouaux, E.
Deposit date:2016-03-09
Release date:2016-04-20
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (13.5 Å)
Cite:Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016
5IOV
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BU of 5iov by Molmil
Cryo-EM structure of GluN1/GluN2B NMDA receptor in the glutamate/glycine/Ro25-6981-bound conformation
Descriptor: 4-[(1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-methylpropyl]phenol, GLUTAMIC ACID, GLYCINE, ...
Authors:Zhu, S, Stein, A.R, Yoshioka, C, Lee, C.H, Goehring, A, Mchaourab, S.H, Gouaux, E.
Deposit date:2016-03-09
Release date:2016-04-20
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016
5IPV
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BU of 5ipv by Molmil
Cryo-EM structure of GluN1/GluN2B NMDA receptor in the DCKA/D-APV-bound conformation, state 1
Descriptor: Ionotropic glutamate receptor subunit NR2B, N-methyl-D-aspartate receptor subunit NR1-8a
Authors:Zhu, S, Stein, A.R, Yoshioka, C, Lee, C.H, Goehring, A, McHaourab, S.H, Gouaux, E.
Deposit date:2016-03-10
Release date:2016-04-20
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (9.25 Å)
Cite:Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016
5IPR
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BU of 5ipr by Molmil
Cryo-EM structure of GluN1/GluN2B NMDA receptor in the DCKA/D-APV-bound conformation, state 3
Descriptor: Ionotropic glutamate receptor subunit NR2B, N-methyl-D-aspartate receptor subunit NR1-8a
Authors:Zhu, S, Stein, A.R, Yoshioka, C, Lee, C.H, Goehring, A, Mchaourab, S.H, Gouaux, E.
Deposit date:2016-03-09
Release date:2016-04-20
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (14.1 Å)
Cite:Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016
5IPQ
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BU of 5ipq by Molmil
Cryo-EM structure of GluN1/GluN2B NMDA receptor in the DCKA/D-APV-bound conformation, state 2
Descriptor: Ionotropic glutamate receptor subunit NR2B, N-methyl-D-aspartate receptor subunit NR1-8a
Authors:Zhu, S, Stein, A.R, Yoshioka, C, Lee, C.H, Goehring, A, Mchaourab, S.H, Gouaux, E.
Deposit date:2016-03-09
Release date:2016-04-20
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (13.5 Å)
Cite:Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016
4NTW
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BU of 4ntw by Molmil
Structure of acid-sensing ion channel in complex with snake toxin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, Basic phospholipase A2 homolog Tx-beta, ...
Authors:Baconguis, I, Bohlen, C.J, Goehring, A, Julius, D, Gouaux, E.
Deposit date:2013-12-02
Release date:2014-02-19
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:X-ray structure of Acid-sensing ion channel 1-snake toxin complex reveals open state of a na(+)-selective channel.
Cell(Cambridge,Mass.), 156, 2014
4NTY
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BU of 4nty by Molmil
Cesium sites in the crystal structure of acid-sensing ion channel in complex with snake toxin
Descriptor: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Acid-sensing ion channel 1, Basic phospholipase A2 homolog Tx-beta, ...
Authors:Baconguis, I, Bohlen, C.J, Goehring, A, Julius, D, Gouaux, E.
Deposit date:2013-12-02
Release date:2014-02-19
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:X-ray structure of Acid-sensing ion channel 1-snake toxin complex reveals open state of a na(+)-selective channel.
Cell(Cambridge,Mass.), 156, 2014
4NTX
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BU of 4ntx by Molmil
Structure of acid-sensing ion channel in complex with snake toxin and amiloride
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3,5-DIAMINO-N-(AMINOIMINOMETHYL)-6-CHLOROPYRAZINECARBOXAMIDE, Acid-sensing ion channel 1, ...
Authors:Baconguis, I, Bohlen, C.J, Goehring, A, Julius, D, Gouaux, E.
Deposit date:2013-12-02
Release date:2014-02-19
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:X-ray structure of Acid-sensing ion channel 1-snake toxin complex reveals open state of a na(+)-selective channel.
Cell(Cambridge,Mass.), 156, 2014
3GIA
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BU of 3gia by Molmil
Crystal Structure of ApcT Transporter
Descriptor: BICINE, DECANE, Uncharacterized protein MJ0609
Authors:Shaffer, P.L, Goehring, A.S, Shankaranarayanan, A, Gouaux, E, New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2009-03-05
Release date:2009-08-18
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Structure and mechanism of a na+-independent amino Acid transporter.
Science, 325, 2009
3GI9
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BU of 3gi9 by Molmil
Crystal Structure of ApcT Transporter Bound to 7F11 Monoclonal Fab Fragment
Descriptor: 7F11 Anti-ApcT Monoclonal Fab Heavy Chain, 7F11 Anti-ApcT Monoclonal Fab Light Chain, Uncharacterized protein MJ0609
Authors:Shaffer, P.L, Goehring, A.S, Shankaranarayanan, A, Gouaux, E, New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2009-03-05
Release date:2009-08-18
Last modified:2017-06-07
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Structure and mechanism of a na+-independent amino Acid transporter.
Science, 325, 2009
3GI8
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BU of 3gi8 by Molmil
Crystal Structure of ApcT K158A Transporter Bound to 7F11 Monoclonal Fab Fragment
Descriptor: 7F11 Anti-ApcT Monoclonal Fab Heavy Chain, 7F11 Anti-ApcT Monoclonal Fab Light Chain, Uncharacterized protein MJ0609
Authors:Shaffer, P.L, Goehring, A.S, Shankaranarayanan, A, Gouaux, E, New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2009-03-05
Release date:2009-08-18
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Structure and mechanism of a na+-independent amino Acid transporter.
Science, 325, 2009
6GMP
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BU of 6gmp by Molmil
CRYSTAL STRUCTURE OF THE PPIASE DOMAIN OF TBPAR42
Descriptor: PARVULIN 42
Authors:Hoenig, D, Rute, A, Hofmann, E, Bayer, P, Gasper, R.
Deposit date:2018-05-28
Release date:2019-03-20
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structural Analysis of the 42 kDa Parvulin ofTrypanosoma brucei.
Biomolecules, 9, 2019
6C14
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BU of 6c14 by Molmil
CryoEM structure of mouse PCDH15-1EC-LHFPL5 complex
Descriptor: LHFPL tetraspan subfamily member 5 protein, Protocadherin-15
Authors:Gouaux, E, Elferich, J, Ge, J.
Deposit date:2018-01-03
Release date:2018-08-15
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structure of mouse protocadherin 15 of the stereocilia tip link in complex with LHFPL5.
Elife, 7, 2018
7USX
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BU of 7usx by Molmil
Structure of Contracted C. elegans TMC-1 complex
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Jeong, H, Clark, S, Gouaux, E.
Deposit date:2022-04-26
Release date:2022-10-19
Last modified:2023-08-09
Method:ELECTRON MICROSCOPY (3.09 Å)
Cite:Structures of the TMC-1 complex illuminate mechanosensory transduction.
Nature, 610, 2022
7USW
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BU of 7usw by Molmil
Structure of Expanded C. elegans TMC-1 complex
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Jeong, H, Clark, S, Gouaux, E.
Deposit date:2022-04-26
Release date:2022-10-19
Last modified:2023-08-09
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structures of the TMC-1 complex illuminate mechanosensory transduction.
Nature, 610, 2022
7USY
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BU of 7usy by Molmil
Structure of C. elegans TMC-1 complex with ARRD-6
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Jeong, H, Clark, S, Gouaux, E.
Deposit date:2022-04-26
Release date:2022-10-19
Last modified:2023-08-09
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Structures of the TMC-1 complex illuminate mechanosensory transduction.
Nature, 610, 2022
2N87
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BU of 2n87 by Molmil
Solution structure of the PPIase domain of TbPar42
Descriptor: Uncharacterized protein
Authors:Rehic, E, Bayer, P.
Deposit date:2015-10-05
Release date:2016-10-12
Last modified:2022-08-24
Method:SOLUTION NMR
Cite:Structural Analysis of the 42 kDa Parvulin of Trypanosoma brucei.
Biomolecules, 9, 2019
2N84
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BU of 2n84 by Molmil
Solution structure of the FHA domain of TbPar42
Descriptor: Uncharacterized protein
Authors:Rehic, E, Bayer, P.
Deposit date:2015-10-04
Release date:2016-10-12
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural Analysis of the 42 kDa Parvulin of Trypanosoma brucei.
Biomolecules, 9, 2019
4TLL
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BU of 4tll by Molmil
Crystal structure of GluN1/GluN2B NMDA receptor, structure 1
Descriptor: 1-AMINOCYCLOPROPANECARBOXYLIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-methylpropyl]phenol, ...
Authors:Gouaux, E, Lee, C.-H, Lu, W.
Deposit date:2014-05-30
Release date:2014-07-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.59 Å)
Cite:NMDA receptor structures reveal subunit arrangement and pore architecture.
Nature, 511, 2014

 

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PDB entries from 2024-03-27

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