Author results

2XMY
  • Download 2xmy
  • View 2xmy
Molmil generated image of 2xmy
DISCOVERY AND CHARACTERISATION OF 2-ANILINO-4-(THIAZOL-5-YL) PYRIMIDINE TRANSCRIPTIONAL CDK INHIBITORS AS ANTICANCER AGENTS
Descriptor:CELL DIVISION PROTEIN KINASE 2, 4-[4-(3,4-DIMETHYL-2-OXO-2,3-DIHYDRO-THIAZOL-5-YL)-PYRIMIDIN-2-YLAMINO]-N-(2-METHOXY-ETHYL)-BENZENESULFONAMIDE
Authors:Wang, S., Griffiths, G., Midgley, C.A., Barnett, A.L., Cooper, M., Grabarek, J., Ingram, L., Jackson, W., Kontopidis, G., McClue, S.J., McInnes, C., McLachlan, J., Meades, C., Mezna, M., Stuart, I., Thomas, M.P., Zheleva, D.I., Lane, D.P., Jackson, R.C., Glover, D.M., Blake, D.G., Fischer, P.M.
Deposit date:2010-07-29
Release date:2010-11-10
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discovery and Characterisation of 2-Anilino-4-(Thiazol-5-Yl)Pyrimidine Transcriptional Cdk Inhibitors as Anticancer Agents
Chem.Biol., 17, 2010
2XNB
  • Download 2xnb
  • View 2xnb
Molmil generated image of 2xnb
DISCOVERY AND CHARACTERISATION OF 2-ANILINO-4-(THIAZOL-5-YL) PYRIMIDINE TRANSCRIPTIONAL CDK INHIBITORS AS ANTICANCER AGENTS
Descriptor:CELL DIVISION PROTEIN KINASE 2, 3,4-DIMETHYL-5-(2-{[(1Z)-4-PIPERAZIN-1-YLCYCLOHEXA-2,4-DIEN-1-YLIDENE]AMINO}PYRIMIDIN-4-YL)-1,3-THIAZOL-2(3H)-ONE
Authors:Wang, S., Griffiths, G., Midgley, C.A., Barnett, A.L., Cooper, M., Grabarek, J., Ingram, L., Jackson, W., Kontopidis, G., McClue, S.J., McInnes, C., McLachlan, J., Meades, C., Mezna, M., Stuart, I., Thomas, M.P., Zheleva, D.I., Lane, D.P., Jackson, R.C., Glover, D.M., Blake, D.G., Fischer, P.M.
Deposit date:2010-08-01
Release date:2010-11-10
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Discovery and Characterisation of 2-Anilino-4-(Thiazol-5-Yl)Pyrimidine Transcriptional Cdk Inhibitors as Anticancer Agents
Chem.Biol., 17, 2010
4CA9
  • Download 4ca9
  • View 4ca9
Molmil generated image of 4ca9
STRUCTURE OF THE NUCLEOPLASMIN-LIKE N-TERMINAL DOMAIN OF DROSOPHILA FKBP39
Descriptor:39 KDA FK506-BINDING NUCLEAR PROTEIN
Authors:Artero, J., Forsyth, T., Callow, P., Watson, A.A., Zhang, W., Laue, E.D., Edlich-Muth, C., Przewloka, M.
Deposit date:2013-10-07
Release date:2014-10-29
Last modified:2015-05-13
Method:SOLUTION NMR
Cite:The Pentameric Nucleoplasmin Fold is Present in Drosophila Fkbp39 and a Large Number of Chromatin-Related Proteins.
J.Mol.Biol., 427, 2015
4PBY
  • Download 4pby
  • View 4pby
Molmil generated image of 4pby
STRUCTURE OF THE HUMAN RBAP48-MTA1(656-686) COMPLEX
Descriptor:Histone-binding protein RBBP4, Metastasis-associated protein MTA1, ISOPROPYL ALCOHOL
Authors:Murthy, A., Lejon, S., Alqarni, S.S.M., Silva, A.P.G., Watson, A.A., Mackay, J.P., Laue, E.D.
Deposit date:2014-04-14
Release date:2014-06-11
Last modified:2014-06-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Insight into the architecture of the NuRD complex: Structure of the RbAp48-MTA1 sub-complex.
J.Biol.Chem., 289, 2014
4PBZ
  • Download 4pbz
  • View 4pbz
Molmil generated image of 4pbz
STRUCTURE OF THE HUMAN RBAP48-MTA1(670-695) COMPLEX
Descriptor:Histone-binding protein RBBP4, Metastasis-associated protein MTA1
Authors:Murthy, A., Pei, X.Y., Watson, A.A., Silva, A.P.G., Mackay, J.P., Laue, E.D.
Deposit date:2014-04-14
Release date:2014-06-11
Last modified:2015-02-04
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Insight into the architecture of the NuRD complex: Structure of the RbAp48-MTA1 sub-complex.
J.Biol.Chem., 289, 2014
4PC0
  • Download 4pc0
  • View 4pc0
Molmil generated image of 4pc0
STRUCTURE OF THE HUMAN RBAP48-MTA1(670-711) COMPLEX
Descriptor:Histone-binding protein RBBP4, Metastasis-associated protein MTA1, GLYCEROL, ...
Authors:Alqarni, S.S.M., Silva, A.P.G., Mackay, J.P., Laue, E.D.
Deposit date:2014-04-14
Release date:2014-06-11
Last modified:2015-02-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Insight into the architecture of the NuRD complex: Structure of the RbAp48-MTA1 sub-complex.
J.Biol.Chem., 289, 2014
4WSF
  • Download 4wsf
  • View 4wsf
Molmil generated image of 4wsf
FALAFEL EVH1 DOMAIN BOUND TO CENP-C FIM
Descriptor:Serine/threonine-protein phosphatase 4 regulatory subunit 3, Cenp-C, SULFATE ION
Authors:Lefevre, S.R., Singleton, M.R.
Deposit date:2014-10-27
Release date:2014-12-10
Last modified:2015-01-14
Method:X-RAY DIFFRACTION (1.501 Å)
Cite:Centromeric binding and activity of Protein Phosphatase 4.
Nat Commun, 6, 2015