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6CPS
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BU of 6cps by Molmil
Crystal structure of the bromodomain of human ATAD2 with a disulfide bridge
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ATPase family AAA domain-containing protein 2, SULFATE ION
Authors:Glass, K.C, Eckenroth, B.E, Carlson, S.
Deposit date:2018-03-14
Release date:2018-12-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Disulfide bridge formation influences ligand recognition by the ATAD2 bromodomain.
Proteins, 87, 2019
6VEO
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BU of 6veo by Molmil
ATAD2B bromodomain in complex with 4-({[(3R,4R)-4-{[3-methyl-5-(5-methylpyridin-3-yl)-2-oxo-1,2-dihydro-1,7-naphthyridin-8-yl]amino}piperidin-3-yl]oxy}methyl)-1lambda~6~-thiane-1,1-dione (compound 38)
Descriptor: 4-({[(3R,4R)-4-{[3-methyl-5-(5-methylpyridin-3-yl)-2-oxo-1,2-dihydro-1,7-naphthyridin-8-yl]amino}piperidin-3-yl]oxy}methyl)-1lambda~6~-thiane-1,1-dione, ATPase family AAA domain-containing protein 2B, SULFATE ION
Authors:Glass, K.C.
Deposit date:2020-01-02
Release date:2020-10-28
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Insights into the Recognition of Mono- and Diacetylated Histones by the ATAD2B Bromodomain.
J.Med.Chem., 63, 2020
7M97
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BU of 7m97 by Molmil
Crystal structure of the bromodomain from Plasmodium falciparum bromodomain protein 1
Descriptor: Bromodomain protein 1
Authors:Glass, K.C.
Deposit date:2021-03-30
Release date:2021-05-26
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the bromodomain from Plasmodium falciparum bromodomain protein 1
To Be Published
4QYL
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BU of 4qyl by Molmil
Crystal Structure of the human BRPF1 bromodomain in complex with a histone H2AK5ac peptide
Descriptor: Histone H2A type 1, Peregrin, SULFATE ION
Authors:Lubula, M.Y, Glass, K.C.
Deposit date:2014-07-24
Release date:2014-09-24
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural insights into recognition of acetylated histone ligands by the BRPF1 bromodomain.
Febs Lett., 588, 2014
4QYD
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BU of 4qyd by Molmil
Crystal Structure of the human BRPF1 bromodomain in complex with a histone H4K12ac peptide
Descriptor: Histone H4, Peregrin
Authors:Lubula, M.Y, Glass, K.C.
Deposit date:2014-07-24
Release date:2014-09-24
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Structural insights into recognition of acetylated histone ligands by the BRPF1 bromodomain.
Febs Lett., 588, 2014
3MDF
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BU of 3mdf by Molmil
Crystal structure of the RRM domain of Cyclophilin 33
Descriptor: Peptidyl-prolyl cis-trans isomerase E
Authors:Hom, R.A, Chang, P.Y, Roy, S, Mussleman, C.A, Glass, K.C, Seleznevia, A.I, Gozani, O, Ismagilov, R.F, Cleary, M.L, Kutateladze, T.G.
Deposit date:2010-03-30
Release date:2010-05-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Molecular mechanism of MLL PHD3 and RNA recognition by the Cyp33 RRM domain.
J.Mol.Biol., 400, 2010
7M98
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BU of 7m98 by Molmil
ATAD2 bromodomain complexed with histone H4K5ac (res 1-10) ligand
Descriptor: ATPase family AAA domain-containing protein 2, Histone H4
Authors:Malone, K.L, Phillips, M, Nix, J.C, Glass, K.C.
Deposit date:2021-03-30
Release date:2021-09-22
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Coordination of Di-Acetylated Histone Ligands by the ATAD2 Bromodomain.
Int J Mol Sci, 22, 2021
7RL2
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BU of 7rl2 by Molmil
Crystal Structure of the Human Cytochrome P450 2C9*8 (CYP2C9*8) Genetic Variant in Complex with the Drug Losartan
Descriptor: Cytochrome P450 2C9, PHOSPHATE ION, POTASSIUM ION, ...
Authors:Shah, M.B.
Deposit date:2021-07-23
Release date:2021-10-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Insights into the Genetic Variations of Human Cytochrome P450 2C9: Structural Analysis, Characterization and Comparison.
Int J Mol Sci, 22, 2021
3LH0
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BU of 3lh0 by Molmil
Crystal structure of the 53BP1 tandem tudor domain in complex with p53K372me2
Descriptor: DIMETHYLATED p53 LYSINE 372 PEPTIDE, SULFATE ION, TRIETHYLENE GLYCOL, ...
Authors:Roy, S, Kutateladze, T.G.
Deposit date:2010-01-21
Release date:2010-03-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insight into p53 recognition by the 53BP1 tandem Tudor domain.
J.Mol.Biol., 398, 2010
3LGF
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BU of 3lgf by Molmil
Crystal structure of the 53BP1 tandem tudor domain in complex with p53K370me2
Descriptor: DIMETHYLATED p53 Lysine 370 PEPTIDE, SULFATE ION, TRIETHYLENE GLYCOL, ...
Authors:Roy, S, Kutateladze, T.G.
Deposit date:2010-01-20
Release date:2010-03-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural insight into p53 recognition by the 53BP1 tandem Tudor domain.
J.Mol.Biol., 398, 2010
3LGL
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BU of 3lgl by Molmil
Crystal structure of the 53BP1 tandem tudor domain in complex with p53K382me2
Descriptor: DIMETHYLATED p53 LYSINE 382 PEPTIDE, SULFATE ION, TRIETHYLENE GLYCOL, ...
Authors:Roy, S, Kutateladze, T.G.
Deposit date:2010-01-20
Release date:2010-03-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural insight into p53 recognition by the 53BP1 tandem Tudor domain.
J.Mol.Biol., 398, 2010
6VLT
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BU of 6vlt by Molmil
Crystal Structure of Human P450 2C9*2 Genetic Variant in Complex with Losartan
Descriptor: 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2C9, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Shah, M.B.
Deposit date:2020-01-25
Release date:2020-09-30
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.12 Å)
Cite:Structure of Cytochrome P450 2C9*2 in Complex with Losartan: Insights into the Effect of Genetic Polymorphism.
Mol.Pharmacol., 98, 2020

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