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8SLV
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BU of 8slv by Molmil
Structure of a salivary alpha-glucosidase from the mosquito vector Aedes aegypti.
Descriptor: 1,3-PROPANDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Gittis, A.G, Williams, A.E, Garboczi, D, Calvo, E.
Deposit date:2023-04-24
Release date:2024-03-20
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Structural and functional comparisons of salivary alpha-glucosidases from the mosquito vectors Aedes aegypti, Anopheles gambiae, and Culex quinquefasciatus.
Insect Biochem.Mol.Biol., 167, 2024
1NZN
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BU of 1nzn by Molmil
Cytosolic domain of the human mitchondrial fission protein Fis1 adopts a TPR fold
Descriptor: Fission protein Fis1p, GLYCEROL, SULFATE ION
Authors:Gittis, A.G, Dohm, J.A, Hill, R.B.
Deposit date:2003-02-18
Release date:2004-03-02
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Cytosolic domain of the human mitchondrial fission protein Fis1 adopts a TPR fold
Proteins, 54, 2004
5EJ0
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BU of 5ej0 by Molmil
The vaccinia virus H3 envelope protein, a major target of neutralizing antibodies, exhibits a glycosyltransferase fold and binds UDP-Glucose
Descriptor: 1,2-ETHANEDIOL, 1,3-PROPANDIOL, 2-(2-METHOXYETHOXY)ETHANOL, ...
Authors:Singh, K, Gittis, A.G, Gitti, R.K, Ostazesky, S.A, Su, H.P, Garboczi, D.N.
Deposit date:2015-10-30
Release date:2016-03-16
Last modified:2016-05-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Vaccinia Virus H3 Envelope Protein, a Major Target of Neutralizing Antibodies, Exhibits a Glycosyltransferase Fold and Binds UDP-Glucose.
J.Virol., 90, 2016
1BUQ
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BU of 1buq by Molmil
SOLUTION STRUCTURE OF DELTA-5-3-KETOSTEROID ISOMERASE COMPLEXED WITH THE STEROID 19-NORTESTOSTERONE-HEMISUCCINATE
Descriptor: PROTEIN (3-KETOSTEROID ISOMERASE-19-NORTESTOSTERONE-HEMISUCCINATE), SUCCINIC ACID MONO-(13-METHYL-3-OXO-2,3,6,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-17-YL) ESTER
Authors:Massiah, M.A, Abeygunawardana, C, Gittis, A.G, Mildvan, A.S.
Deposit date:1998-09-04
Release date:1999-01-20
Last modified:2021-11-03
Method:SOLUTION NMR
Cite:Solution structure of Delta 5-3-ketosteroid isomerase complexed with the steroid 19-nortestosterone hemisuccinate.
Biochemistry, 37, 1998
6OHG
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BU of 6ohg by Molmil
Structure of Plasmodium falciparum vaccine candidate Pfs230D1M in complex with the Fab of a transmission blocking antibody
Descriptor: 1,2-ETHANEDIOL, 1,3-PROPANDIOL, 4F12 Heavy chain, ...
Authors:Garboczi, D.N, Singh, K, Gittis, A.G.
Deposit date:2019-04-05
Release date:2020-06-17
Last modified:2021-03-31
Method:X-RAY DIFFRACTION (2.385 Å)
Cite:Structure and function of a malaria transmission blocking vaccine targeting Pfs230 and Pfs230-Pfs48/45 proteins.
Commun Biol, 3, 2020
7TXW
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BU of 7txw by Molmil
Crystal structure of the complex of the malaria sexual stage protein and vaccine target Pfs25 with the Fab fragment of a transmission blocking antibody 1G2
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ETHANOL, ...
Authors:Singh, K, Gittis, A.G, Garboczi, D.N.
Deposit date:2022-02-10
Release date:2023-04-12
Last modified:2023-05-24
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Structural and immunological differences in Plasmodium falciparum sexual stage transmission-blocking vaccines comprised of Pfs25-EPA nanoparticles.
Npj Vaccines, 8, 2023
4QVB
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BU of 4qvb by Molmil
Mycobacterium tuberculosis protein Rv1155 in complex with co-enzyme F420
Descriptor: 1,2-ETHANEDIOL, 1,3-PROPANDIOL, COENZYME F420, ...
Authors:Mashalidis, E.H, Gittis, A.G, Tomczak, A, Abell, C, Barry III, C.E, Garboczi, D.N.
Deposit date:2014-07-14
Release date:2015-02-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular insights into the binding of coenzyme F420 to the conserved protein Rv1155 from Mycobacterium tuberculosis.
Protein Sci., 24, 2015
1AHQ
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BU of 1ahq by Molmil
RECOMBINANT ACTOPHORIN
Descriptor: ACTOPHORIN
Authors:Leonard, S.A, Gittis, A.G, Petrella, E.C, Pollard, T.D, Lattman, E.E.
Deposit date:1997-04-10
Release date:1997-09-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the actin-binding protein actophorin from Acanthamoeba.
Nat.Struct.Biol., 4, 1997
1HC8
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BU of 1hc8 by Molmil
CRYSTAL STRUCTURE OF A CONSERVED RIBOSOMAL PROTEIN-RNA COMPLEX
Descriptor: 58 NUCLEOTIDE RIBOSOMAL 23S RNA DOMAIN, MAGNESIUM ION, OSMIUM ION, ...
Authors:Conn, G.L, Draper, D.E, Lattman, E.E, Gittis, A.G.
Deposit date:2001-04-27
Release date:2002-05-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A Compact RNA Tertiary Structure Contains a Buried Backbone-K+ Complex
J.Mol.Biol., 318, 2002
6CJ6
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BU of 6cj6 by Molmil
Structure of the poxvirus protein F9
Descriptor: 1,2-ETHANEDIOL, 1,3-PROPANDIOL, 2-(2-METHOXYETHOXY)ETHANOL, ...
Authors:Diesterbeck, U.S, Gittis, A.G, Garboczi, D.N, Moss, B.
Deposit date:2018-02-26
Release date:2019-03-06
Last modified:2019-09-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The 2.1 angstrom structure of protein F9 and its comparison to L1, two components of the conserved poxvirus entry-fusion complex.
Sci Rep, 8, 2018
6V4C
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BU of 6v4c by Molmil
Culex quinquefasciatus D7 long form 1- CxD7L1 in complex with ADP
Descriptor: 1,2-ETHANEDIOL, 2-ETHOXYETHANOL, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Calvo, E, Garboczi, D.N, Martin-Martin, I, Gittis, A.G.
Deposit date:2019-11-27
Release date:2020-06-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:ADP binding by the Culex quinquefasciatus mosquito D7 salivary protein enhances blood feeding on mammals.
Nat Commun, 11, 2020
2I9L
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BU of 2i9l by Molmil
Structure of Fab 7D11 from a neutralizing antibody against the poxvirus L1 protein
Descriptor: Antibody 7D11 heavy chain, Antibody 7D11 light chain, GLYCEROL, ...
Authors:Su, H.P, Golden, J.W, Gittis, A.G, Moss, B, Hooper, J.W, Garboczi, D.N.
Deposit date:2006-09-05
Release date:2007-09-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for the binding of the neutralizing antibody, 7D11, to the poxvirus L1 protein
Virology, 368, 2007
7U1N
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BU of 7u1n by Molmil
Crystal structure of the Anopheles darlingi AD-118 long form D7 salivary protein
Descriptor: 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, 2-ETHOXYETHANOL, ...
Authors:Alvarenga, P.H, Gittis, A.G, Garboczi, D.N, Andersen, J.F.
Deposit date:2022-02-21
Release date:2022-05-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Functional aspects of evolution in a cluster of salivary protein genes from mosquitoes.
Insect Biochem.Mol.Biol., 146, 2022
7KC8
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BU of 7kc8 by Molmil
Salivary protein from Culex quinquefasciatus that belongs to the Cysteins and Tryptophan-Rich (CWRC) family
Descriptor: 16.4 kDa salivary peptide, ACETIC ACID
Authors:Garboczi, D.N, Gittis, A.G, Kern, O, Martin-Martin, I.
Deposit date:2020-10-05
Release date:2021-06-02
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The structures of two salivary proteins from the West Nile vector Culex quinquefasciatus reveal a beta-trefoil fold with putative sugar binding properties
Curr Res Struct Biol, 3, 2021
7KCG
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BU of 7kcg by Molmil
Salivary protein from Culex quiquefasciatus that belongs to the Cysteine and Tryptophan-Rich (CWRC) family
Descriptor: 16 kDa salivary peptide, FORMIC ACID
Authors:Garboczi, N.D, Gittis, A.G, Kern, O, Martin-Martin, I, Calvo, E.
Deposit date:2020-10-05
Release date:2021-06-02
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:The structures of two salivary proteins from the West Nile vector Culex quinquefasciatus reveal a beta-trefoil fold with putative sugar binding properties
Curr Res Struct Biol, 3, 2021
1ZJG
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BU of 1zjg by Molmil
13mer-co
Descriptor: 5'-D(*AP*TP*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*T)-3', 5'-D(*TP*AP*GP*CP*CP*CP*CP*GP*CP*CP*CP*CP*A)-3', COBALT HEXAMMINE(III), ...
Authors:Dohm, J.A, Hsu, M.H, Hwu, J.R, Huang, R.C, Moudrianakis, E.N, Lattman, E.E, Gittis, A.G.
Deposit date:2005-04-28
Release date:2005-05-10
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Influence of Ions, Hydration, and the Transcriptional Inhibitor P4N on the Conformations of the Sp1 Binding Site.
J.Mol.Biol., 349, 2005
1ZJF
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BU of 1zjf by Molmil
12mer-spd-P4N
Descriptor: 5'-D(*AP*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*T)-3', 5'-D(*TP*AP*GP*CP*CP*CP*CP*GP*CP*CP*CP*C)-3'
Authors:Dohm, J.A, Hsu, M.H, Hwu, J.R, Huang, R.C, Moudrianakis, E.N, Lattman, E.E, Gittis, A.G.
Deposit date:2005-04-28
Release date:2005-05-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Influence of Ions, Hydration, and the Transcriptional Inhibitor P4N on the Conformations of the Sp1 Binding Site.
J.Mol.Biol., 349, 2005
1ZJE
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BU of 1zje by Molmil
12mer-spd
Descriptor: 5'-D(*AP*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*T)-3', 5'-D(*TP*AP*GP*CP*CP*CP*CP*GP*CP*CP*CP*C)-3'
Authors:Dohm, J.A, Hsu, M.H, Hwu, J.R, Huang, R.C, Moudrianakis, E.N, Lattman, E.E, Gittis, A.G.
Deposit date:2005-04-28
Release date:2005-05-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Influence of Ions, Hydration, and the Transcriptional Inhibitor P4N on the Conformations of the Sp1 Binding Site.
J.Mol.Biol., 349, 2005
1SND
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BU of 1snd by Molmil
STAPHYLOCOCCAL NUCLEASE DIMER CONTAINING A DELETION OF RESIDUES 114-119 COMPLEXED WITH CALCIUM CHLORIDE AND THE COMPETITIVE INHIBITOR DEOXYTHYMIDINE-3',5'-DIPHOSPHATE
Descriptor: STAPHYLOCOCCAL NUCLEASE DIMER
Authors:Green, S.M, Gittis, A.G, Meeker, A.K, Lattman, E.E.
Deposit date:1996-08-23
Release date:1997-04-21
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:One-step evolution of a dimer from a monomeric protein.
Nat.Struct.Biol., 2, 1995
1TR5
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BU of 1tr5 by Molmil
Room temperature structure of Staphylococcal nuclease variant truncated Delta+PHS I92E
Descriptor: CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease
Authors:Nguyen, D.M, Leila Reynald, R, Gittis, A.G, Lattman, E.E.
Deposit date:2004-06-20
Release date:2004-07-06
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:X-ray and thermodynamic studies of staphylococcal nuclease variants I92E and I92K: insights into polarity of the protein interior
J.Mol.Biol., 341, 2004
1TT2
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BU of 1tt2 by Molmil
Cryogenic crystal structure of Staphylococcal nuclease variant truncated Delta+PHS I92K
Descriptor: CALCIUM ION, DIMETHYL SULFOXIDE, GLYCEROL, ...
Authors:Nguyen, D.M, Reynald, R.L, Gittis, A.G, Lattman, E.E.
Deposit date:2004-06-21
Release date:2004-07-06
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:X-ray and thermodynamic studies of staphylococcal nuclease variants I92E and I92K: insights into polarity of the protein interior
J.Mol.Biol., 341, 2004
1TQO
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BU of 1tqo by Molmil
Cryogenic Crystal Structure of Staphylococcal Nuclease Variant truncated Delta+PHS I92E
Descriptor: Thermonuclease
Authors:Nguyen, D.M, Reynald, R.L, Gittis, A.G, Lattman, E.E.
Deposit date:2004-06-17
Release date:2004-07-06
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray and thermodynamic studies of staphylococcal nuclease variants I92E and I92K: insights into polarity of the protein interior
J.Mol.Biol., 341, 2004
1EX3
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BU of 1ex3 by Molmil
CRYSTAL STRUCTURE OF BOVINE CHYMOTRYPSINOGEN A (TETRAGONAL)
Descriptor: CHYMOTRYPSINOGEN A
Authors:Pjura, P.E, Lenhoff, A.M, Leonard, S.A, Gittis, A.G.
Deposit date:2000-04-28
Release date:2000-05-17
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (3 Å)
Cite:Protein crystallization by design: chymotrypsinogen without precipitants.
J.Mol.Biol., 300, 2000
2OEO
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BU of 2oeo by Molmil
Cryogenic crystal structure of Staphylococcal Nuclease variant truncated Delta+PHS I92D
Descriptor: CALCIUM ION, Staphylococcal thermonuclease, THYMIDINE-3',5'-DIPHOSPHATE
Authors:Reynald, R.L, Lattman, E.E, Gittis, A.G.
Deposit date:2006-12-30
Release date:2008-03-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Buried Charges and Water in the Protein Interior: Reality or Fiction?
To be Published
1GEN
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BU of 1gen by Molmil
C-TERMINAL DOMAIN OF GELATINASE A
Descriptor: CALCIUM ION, CHLORIDE ION, GELATINASE A, ...
Authors:Libson, A.M, Gittis, A.G, Collier, I.E, Marmer, B.L, Goldberg, G.G, Lattman, E.E.
Deposit date:1995-07-19
Release date:1996-08-17
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structure of the haemopexin-like C-terminal domain of gelatinase A.
Nat.Struct.Biol., 2, 1995

 

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