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3U7D
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BU of 3u7d by Molmil
Crystal structure of the KRIT1/CCM1 FERM domain in complex with the heart of glass (HEG1) cytoplasmic tail
Descriptor: Krev interaction trapped protein 1, Protein HEG homolog 1
Authors:Gingras, A.R, Liu, J.J, Ginsberg, M.H, Assembly, Dynamics and Evolution of Cell-Cell and Cell-Matrix Adhesions (CELLMAT)
Deposit date:2011-10-13
Release date:2012-09-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structural basis of the junctional anchorage of the cerebral cavernous malformations complex.
J.Cell Biol., 199, 2012
3G9W
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BU of 3g9w by Molmil
Crystal Structure of Talin2 F2-F3 in Complex with the Integrin Beta1D Cytoplasmic Tail
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, Integrin beta-1D, ...
Authors:Anthis, N.J, Wegener, K.L, Ye, F, Kim, C, Lowe, E.D, Vakonakis, I, Bate, N, Critchley, D.R, Ginsberg, M.H, Campbell, I.D.
Deposit date:2009-02-15
Release date:2009-10-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.165 Å)
Cite:The structure of an integrin/talin complex reveals the basis of inside-out signal transduction
Embo J., 28, 2009
1N3K
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BU of 1n3k by Molmil
Solution structure of phosphoprotein enriched in astrocytes 15 kDa (PEA-15)
Descriptor: Astrocytic phosphoprotein PEA-15
Authors:Hill, J.M, Vaidyanathan, H, Ramos, J.W, Ginsberg, M.H, Werner, M.H.
Deposit date:2002-10-28
Release date:2003-01-14
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Recognition of ERK MAP Kinase by PEA-15 Reveals a Common Docking Site Within the Death Domain and Death Effector Domain
Embo J., 21, 2002
1Y19
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BU of 1y19 by Molmil
Structural basis for phosphatidylinositol phosphate kinase type I-gamma binding to talin at focal adhesions
Descriptor: Phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma, Talin 1
Authors:de Pereda, J.M, Wegener, K, Santelli, E, Bate, N, Ginsberg, M.H, Critchley, D.R, Campbell, I.D, Liddington, R.C.
Deposit date:2004-11-17
Release date:2005-01-04
Last modified:2016-11-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural bases for phosphatidylinositol phosphate kinase type I-gamma binding to talin at focal adhesions
J.Biol.Chem., 280, 2005
4X6R
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BU of 4x6r by Molmil
An Isoform-specific Myristylation Switch Targets RIIb PKA Holoenzymes to Membranes
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
Authors:Zhang, P, Ye, F, Bastidas, A.C, Kornev, A.P, Ginsberg, M.H, Wu, J, Taylor, S.S.
Deposit date:2014-12-09
Release date:2015-07-22
Last modified:2020-06-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:An Isoform-Specific Myristylation Switch Targets Type II PKA Holoenzymes to Membranes.
Structure, 23, 2015
4X6Q
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BU of 4x6q by Molmil
An Isoform-specific Myristylation Switch Targets RIIb PKA Holoenzymes to Membranes
Descriptor: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase type II-beta regulatory subunit
Authors:Zhang, P, Ye, F, Bastidas, A.C, Kornev, A.P, Ginsberg, M.H, Taylor, S.S.
Deposit date:2014-12-08
Release date:2015-07-22
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:An Isoform-Specific Myristylation Switch Targets Type II PKA Holoenzymes to Membranes.
Structure, 23, 2015
2K9J
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BU of 2k9j by Molmil
Integrin alphaIIb-beta3 transmembrane complex
Descriptor: Integrin alpha-IIb light chain, Integrin beta-3
Authors:Lau, T, Kim, C, Ginsberg, M.H, Ulmer, T.S.
Deposit date:2008-10-15
Release date:2009-03-24
Last modified:2021-10-20
Method:SOLUTION NMR
Cite:The structure of the integrin alphaIIbbeta3 transmembrane complex explains integrin transmembrane signalling
Embo J., 28, 2009
2NA9
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BU of 2na9 by Molmil
Transmembrane Structure of the P441A Mutant of the Cytokine Receptor Common Subunit beta
Descriptor: Cytokine receptor common subunit beta
Authors:Schmidt, T, Ye, F, Situ, A.J, An, W, Ginsberg, M.H, Ulmer, T.S.
Deposit date:2015-12-21
Release date:2016-07-06
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:A Conserved Ectodomain-Transmembrane Domain Linker Motif Tunes the Allosteric Regulation of Cell Surface Receptors.
J.Biol.Chem., 291, 2016
2NA8
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BU of 2na8 by Molmil
Transmembrane Structure of the Cytokine Receptor Common Subunit beta
Descriptor: Cytokine receptor common subunit beta
Authors:Schmidt, T, Ye, F, Situ, A.J, An, W, Ginsberg, M.H, Ulmer, T.S.
Deposit date:2015-12-21
Release date:2016-07-06
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:A Conserved Ectodomain-Transmembrane Domain Linker Motif Tunes the Allosteric Regulation of Cell Surface Receptors.
J.Biol.Chem., 291, 2016
2RMZ
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BU of 2rmz by Molmil
Bicelle-embedded integrin beta3 transmembrane segment
Descriptor: Integrin beta-3
Authors:Lau, T.L, Partridge, A.W, Ginsberg, M.H, Ulmer, T.S.
Deposit date:2007-12-04
Release date:2008-03-18
Last modified:2022-12-21
Method:SOLUTION NMR
Cite:Structure of the Integrin beta3 Transmembrane Segment in Phospholipid Bicelles and Detergent Micelles
Biochemistry, 47, 2008
2RN0
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BU of 2rn0 by Molmil
Micelle-embedded integrin beta3 transmembrane segment
Descriptor: Integrin beta-3
Authors:Lau, T.L, Partridge, A.W, Ginsberg, M.H, Ulmer, T.S.
Deposit date:2007-12-04
Release date:2008-03-18
Last modified:2022-12-21
Method:SOLUTION NMR
Cite:Structure of the Integrin beta3 Transmembrane Segment in Phospholipid Bicelles and Detergent Micelles
Biochemistry, 47, 2008
1MK7
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BU of 1mk7 by Molmil
CRYSTAL STRUCTURE OF AN INTEGRIN BETA3-TALIN CHIMERA
Descriptor: Integrin Beta3, TALIN
Authors:Garcia-Alvarez, B, De Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C.
Deposit date:2002-08-28
Release date:2003-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Determinants of Integrin Recognition by Talin
Mol.Cell, 11, 2003
1MIX
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BU of 1mix by Molmil
Crystal structure of a FERM domain of Talin
Descriptor: Talin
Authors:Garcia-Alvarez, B, de Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C.
Deposit date:2002-08-23
Release date:2003-01-28
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural determinants of integrin recognition by talin
Mol.Cell, 11, 2003
1MIZ
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BU of 1miz by Molmil
Crystal structure of an integrin beta3-talin chimera
Descriptor: TALIN, integrin beta3
Authors:Garcia-Alvarez, B, de Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C.
Deposit date:2002-08-23
Release date:2003-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural determinants of integrin recognition by talin
Mol.Cell, 11, 2003
1MK9
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BU of 1mk9 by Molmil
CRYSTAL STRUCTURE OF AN INTEGRIN BETA3-TALIN CHIMERA
Descriptor: Integrin Beta3, TALIN
Authors:Garcia-Alvarez, B, De Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C.
Deposit date:2002-08-28
Release date:2003-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Determinants of Integrin Recognition by Talin
Mol.Cell, 11, 2003
5KHO
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BU of 5kho by Molmil
Rasip1 RA domain in complex with Rap1B
Descriptor: GLYCEROL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Gingras, A.R.
Deposit date:2016-06-15
Release date:2016-10-19
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Structural Basis of Dimeric Rasip1 RA Domain Recognition of the Ras Subfamily of GTP-Binding Proteins.
Structure, 24, 2016
5KHQ
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BU of 5khq by Molmil
Rasip1 RA domain
Descriptor: GLYCEROL, Ras-interacting protein 1
Authors:Gingras, A.R.
Deposit date:2016-06-15
Release date:2016-10-19
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis of Dimeric Rasip1 RA Domain Recognition of the Ras Subfamily of GTP-Binding Proteins.
Structure, 24, 2016
3DYJ
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BU of 3dyj by Molmil
Crystal Structure of the R11R12 Domains of Talin
Descriptor: TALIN-1
Authors:Gingras, A.R, Joyce, M.G, Critchley, D.R, Emsley, J.
Deposit date:2008-07-28
Release date:2009-01-27
Last modified:2021-08-25
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural determinants of integrin binding to the talin rod
J.Biol.Chem., 284, 2009
4HDQ
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BU of 4hdq by Molmil
Crystal Structure of the Ternary Complex of KRIT1 bound to both the Rap1 GTPase and the Heart of Glass (HEG1) cytoplasmic tail
Descriptor: GLYCEROL, Krev interaction trapped protein 1, MAGNESIUM ION, ...
Authors:Gingras, A.R.
Deposit date:2012-10-02
Release date:2013-07-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The Structure of the Ternary Complex of Krev Interaction Trapped 1 (KRIT1) Bound to Both the Rap1 GTPase and the Heart of Glass (HEG1) Cytoplasmic Tail.
J.Biol.Chem., 288, 2013
4HDO
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BU of 4hdo by Molmil
Crystal structure of the binary Complex of KRIT1 bound to the Rap1 GTPase
Descriptor: GLYCEROL, Krev interaction trapped protein 1, MAGNESIUM ION, ...
Authors:Gingras, A.R.
Deposit date:2012-10-02
Release date:2013-07-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:The Structure of the Ternary Complex of Krev Interaction Trapped 1 (KRIT1) Bound to Both the Rap1 GTPase and the Heart of Glass (HEG1) Cytoplasmic Tail.
J.Biol.Chem., 288, 2013
2H7E
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BU of 2h7e by Molmil
Solution structure of the talin F3 domain in complex with a chimeric beta3 integrin-PIP kinase peptide- minimized average structure
Descriptor: Chimera of 24-mer peptide from Integrin beta-3 and 10-mer peptide from Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma, Talin-1
Authors:Wegener, K.L.
Deposit date:2006-06-02
Release date:2007-01-30
Last modified:2021-11-10
Method:SOLUTION NMR
Cite:Structural basis of integrin activation by talin
CELL(CAMBRIDGE,MASS.), 128, 2007
2H7D
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BU of 2h7d by Molmil
Solution structure of the talin F3 domain in complex with a chimeric beta3 integrin-PIP kinase peptide
Descriptor: Chimera of 24-mer peptide from Integrin beta-3 and 10-mer peptide from Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma, Talin-1
Authors:Wegener, K.L.
Deposit date:2006-06-02
Release date:2007-01-30
Last modified:2021-11-10
Method:SOLUTION NMR
Cite:Structural basis of integrin activation by talin
CELL(CAMBRIDGE,MASS.), 128, 2007
2L91
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BU of 2l91 by Molmil
Structure of the Integrin beta3 (A711P,K716A) Transmembrane Segment
Descriptor: Integrin beta-3
Authors:Schmidt, T, Ulmer, T.S.
Deposit date:2011-01-27
Release date:2011-12-21
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Basic amino-acid side chains regulate transmembrane integrin signalling.
Nature, 481, 2012

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