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2X0C
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BU of 2x0c by Molmil
Crystal Structure of the R7R8 domains of Talin
Descriptor: TALIN-1
Authors:Gingras, A.R, Goult, B.T, Bate, N, Barsukov, I.L, Emsley, J, Critchely, D.R.
Deposit date:2009-12-08
Release date:2010-07-07
Last modified:2023-03-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Central Region of Talin Has a Unique Fold that Binds Vinculin and Actin.
J.Biol.Chem., 285, 2010
3C1V
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BU of 3c1v by Molmil
The 1.5 A Crystal structure of Ca2+-bound S100A4
Descriptor: CALCIUM ION, Protein S100-A4
Authors:Gingras, A.R, Barsukov, I.L.
Deposit date:2008-01-24
Release date:2008-04-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of the Ca(2+)-form and Ca(2+)-binding kinetics of metastasis-associated protein, S100A4
Febs Lett., 582, 2008
3DYJ
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BU of 3dyj by Molmil
Crystal Structure of the R11R12 Domains of Talin
Descriptor: TALIN-1
Authors:Gingras, A.R, Joyce, M.G, Critchley, D.R, Emsley, J.
Deposit date:2008-07-28
Release date:2009-01-27
Last modified:2021-08-25
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural determinants of integrin binding to the talin rod
J.Biol.Chem., 284, 2009
5KHQ
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BU of 5khq by Molmil
Rasip1 RA domain
Descriptor: GLYCEROL, Ras-interacting protein 1
Authors:Gingras, A.R.
Deposit date:2016-06-15
Release date:2016-10-19
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis of Dimeric Rasip1 RA Domain Recognition of the Ras Subfamily of GTP-Binding Proteins.
Structure, 24, 2016
5KHO
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BU of 5kho by Molmil
Rasip1 RA domain in complex with Rap1B
Descriptor: GLYCEROL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Gingras, A.R.
Deposit date:2016-06-15
Release date:2016-10-19
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Structural Basis of Dimeric Rasip1 RA Domain Recognition of the Ras Subfamily of GTP-Binding Proteins.
Structure, 24, 2016
1ZW3
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BU of 1zw3 by Molmil
Vinculin Head (0-258) in Complex with the Talin Rod residues 1630-1652
Descriptor: Talin 1, Vinculin
Authors:Gingras, A.R, Ziegler, W.H, Barsukov, I.L, Roberts, G.C, Critchley, D.R, Emsley, J.
Deposit date:2005-06-03
Release date:2005-09-20
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod
J.Biol.Chem., 280, 2005
1ZVZ
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BU of 1zvz by Molmil
Vinculin Head (0-258) in Complex with the Talin Rod Residue 820-844
Descriptor: Talin 1, Vinculin
Authors:Gingras, A.R, Ziegler, W.H, Barsukov, I.L, Roberts, G.C, Critchley, D.R, Emsley, J.
Deposit date:2005-06-03
Release date:2005-09-20
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod
J.Biol.Chem., 280, 2005
1ZW2
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BU of 1zw2 by Molmil
Vinculin Head (0-258) in Complex with the Talin Rod residues 2345-2369
Descriptor: Vinculin, talin
Authors:Gingras, A.R, Ziegler, W.H, Barsukov, I.L, Roberts, G.C, Critchley, D.R, Emsley, J.
Deposit date:2005-06-03
Release date:2005-09-20
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod
J.Biol.Chem., 280, 2005
2B0H
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BU of 2b0h by Molmil
Solution structure of VBS3 fragment of talin
Descriptor: Talin-1
Authors:Gingras, A.R, Vogel, K.P, Steinhoff, H.J, Ziegler, W.H, Patel, B, Emsley, J, Critchley, D.R, Roberts, G.C, Barsukov, I.L.
Deposit date:2005-09-14
Release date:2006-01-17
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Structural and Dynamic Characterization of a Vinculin Binding Site in the Talin Rod
Biochemistry, 45, 2006
1XWJ
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BU of 1xwj by Molmil
Vinculin head (1-258) in complex with the talin vinculin binding site 3 (1945-1969)
Descriptor: Talin, Vinculin
Authors:Gingras, A.R, Papagrigoriou, E, Barsukov, I.L, Critchley, D.R, Emsley, J.
Deposit date:2004-11-01
Release date:2005-10-11
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and Dynamic Characterization of a Vinculin Binding Site in the Talin Rod
Biochemistry, 45, 2006
4HDQ
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BU of 4hdq by Molmil
Crystal Structure of the Ternary Complex of KRIT1 bound to both the Rap1 GTPase and the Heart of Glass (HEG1) cytoplasmic tail
Descriptor: GLYCEROL, Krev interaction trapped protein 1, MAGNESIUM ION, ...
Authors:Gingras, A.R.
Deposit date:2012-10-02
Release date:2013-07-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The Structure of the Ternary Complex of Krev Interaction Trapped 1 (KRIT1) Bound to Both the Rap1 GTPase and the Heart of Glass (HEG1) Cytoplasmic Tail.
J.Biol.Chem., 288, 2013
4HDO
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BU of 4hdo by Molmil
Crystal structure of the binary Complex of KRIT1 bound to the Rap1 GTPase
Descriptor: GLYCEROL, Krev interaction trapped protein 1, MAGNESIUM ION, ...
Authors:Gingras, A.R.
Deposit date:2012-10-02
Release date:2013-07-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:The Structure of the Ternary Complex of Krev Interaction Trapped 1 (KRIT1) Bound to Both the Rap1 GTPase and the Heart of Glass (HEG1) Cytoplasmic Tail.
J.Biol.Chem., 288, 2013
2QDQ
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BU of 2qdq by Molmil
Crystal structure of the talin dimerisation domain
Descriptor: Talin-1
Authors:Gingras, A.R, Putz, N.S.M, Bate, N, Barsukov, I.L, Critchley, D.R.C.
Deposit date:2007-06-21
Release date:2008-01-29
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure of the C-terminal actin-binding domain of talin.
Embo J., 27, 2008
3U7D
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BU of 3u7d by Molmil
Crystal structure of the KRIT1/CCM1 FERM domain in complex with the heart of glass (HEG1) cytoplasmic tail
Descriptor: Krev interaction trapped protein 1, Protein HEG homolog 1
Authors:Gingras, A.R, Liu, J.J, Ginsberg, M.H, Assembly, Dynamics and Evolution of Cell-Cell and Cell-Matrix Adhesions (CELLMAT)
Deposit date:2011-10-13
Release date:2012-09-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structural basis of the junctional anchorage of the cerebral cavernous malformations complex.
J.Cell Biol., 199, 2012
3POJ
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BU of 3poj by Molmil
Crystal structure of MASP-1 CUB2 domain bound to Ethylamine
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ETHANAMINE, ...
Authors:Gingras, A.R, Moody, P.C.E, Wallis, R.
Deposit date:2010-11-22
Release date:2011-08-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.451 Å)
Cite:Structural Basis of Mannan-Binding Lectin Recognition by Its Associated Serine Protease MASP-1: Implications for Complement Activation.
Structure, 19, 2011
3POD
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BU of 3pod by Molmil
Crystal structure of MBL collagen-like peptide
Descriptor: MBL collagen-like peptide
Authors:Gingras, A.R, Moody, P.C.E, Wallis, R.
Deposit date:2010-11-22
Release date:2011-08-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.497 Å)
Cite:Structural Basis of Mannan-Binding Lectin Recognition by Its Associated Serine Protease MASP-1: Implications for Complement Activation.
Structure, 19, 2011
3POI
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BU of 3poi by Molmil
Crystal structure of MASP-1 CUB2 domain bound to Methylamine
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, METHYLAMINE, ...
Authors:Gingras, A.R, Moody, P.C.E, Wallis, R.
Deposit date:2010-11-22
Release date:2011-08-24
Last modified:2011-11-30
Method:X-RAY DIFFRACTION (1.701 Å)
Cite:Structural Basis of Mannan-Binding Lectin Recognition by Its Associated Serine Protease MASP-1: Implications for Complement Activation.
Structure, 19, 2011
3POB
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BU of 3pob by Molmil
Crystal structure of MASP-1 CUB2 domain in complex with the collagen-like domain of MBL
Descriptor: CALCIUM ION, MBL collagen-like peptide, Mannan-binding lectin serine protease 1
Authors:Gingras, A.R, Moody, P.C.E, Wallis, R.
Deposit date:2010-11-22
Release date:2011-08-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Structural Basis of Mannan-Binding Lectin Recognition by Its Associated Serine Protease MASP-1: Implications for Complement Activation.
Structure, 19, 2011
3POG
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BU of 3pog by Molmil
Crystal structure of the MASP-1 CUB2 domain bound to Ca2+
Descriptor: CALCIUM ION, Mannan-binding lectin serine protease 1
Authors:Gingras, A.R, Moody, P.C.E, Wallis, R.
Deposit date:2010-11-22
Release date:2011-08-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.749 Å)
Cite:Structural Basis of Mannan-Binding Lectin Recognition by Its Associated Serine Protease MASP-1: Implications for Complement Activation.
Structure, 19, 2011
3PON
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BU of 3pon by Molmil
Crystal structure of MBL collagen-like peptide
Descriptor: MBL collagen-like peptide
Authors:Gingras, A.R, Moody, P.C.E, Wallis, R.
Deposit date:2010-11-23
Release date:2011-08-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Basis of Mannan-Binding Lectin Recognition by Its Associated Serine Protease MASP-1: Implications for Complement Activation.
Structure, 19, 2011
3POE
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BU of 3poe by Molmil
Crystal structure of the MASP-1 CUB2 domain bound to Ca2+
Descriptor: CALCIUM ION, Mannan-binding lectin serine protease 1
Authors:Gingras, A.R, Moody, P.C.E, Wallis, R.
Deposit date:2010-11-22
Release date:2011-08-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.501 Å)
Cite:Structural Basis of Mannan-Binding Lectin Recognition by Its Associated Serine Protease MASP-1: Implications for Complement Activation.
Structure, 19, 2011
3POF
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BU of 3pof by Molmil
Crystal structure of MASP-1 CUB2 domain bound to Ca2+
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, Mannan-binding lectin serine protease 1, ...
Authors:Gingras, A.R, Moody, P.C.E, Wallis, R.
Deposit date:2010-11-22
Release date:2011-08-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.501 Å)
Cite:Structural Basis of Mannan-Binding Lectin Recognition by Its Associated Serine Protease MASP-1: Implications for Complement Activation.
Structure, 19, 2011
6UZK
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BU of 6uzk by Molmil
Crystal Structure of the Ternary Complex of KRIT1 bound to both the Rap1 GTPase and HKi6
Descriptor: 2-hydroxy-6-methoxynaphthalene-1-carbaldehyde, Krev interaction trapped protein 1, MAGNESIUM ION, ...
Authors:Gingras, A.R.
Deposit date:2019-11-15
Release date:2020-11-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.924 Å)
Cite:Inhibition of the HEG1-KRIT1 interaction increases KLF4 and KLF2 expression in endothelial cells.
Faseb Bioadv, 3, 2021
6OQ4
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BU of 6oq4 by Molmil
Crystal Structure of the Ternary Complex of KRIT1 bound to both the Rap1 GTPase and HKi1
Descriptor: 2-{(Z)-[(2-hydroxynaphthalen-1-yl)methylidene]amino}-N-[(1S)-1-phenylethyl]benzamide, Krev interaction trapped protein 1, MAGNESIUM ION, ...
Authors:Gingras, A.R.
Deposit date:2019-04-25
Release date:2020-06-24
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.754 Å)
Cite:Inhibition of the HEG1-KRIT1 interaction increases KLF4 and KLF2 expression in endothelial cells
Faseb Bioadv, 2021
6OQ3
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BU of 6oq3 by Molmil
Crystal Structure of the Ternary Complex of KRIT1 bound to both the Rap1 GTPase and HKi2
Descriptor: 2-hydroxynaphthalene-1-carbaldehyde, Krev interaction trapped protein 1, MAGNESIUM ION, ...
Authors:Gingras, A.R.
Deposit date:2019-04-25
Release date:2020-06-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Inhibition of the HEG1-KRIT1 interaction increases KLF4 and KLF2 expression in endothelial cells
Faseb Bioadv, 2021

 

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