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6GJ0
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HUMAN IMPASE WITH MN
Descriptor:Inositol monophosphatase 1, MANGANESE (II) ION, GLYCEROL, ...
Authors:Kraft, L.V., Roe, S.M.
Deposit date:2018-05-15
Release date:2018-10-17
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Co-crystallization of human inositol monophosphatase with the lithium mimetic L-690,330.
Acta Crystallogr D Struct Biol, 74, 2018
6GIU
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HUMAN IMPASE WITH L-690330
Descriptor:Inositol monophosphatase 1, MANGANESE (II) ION, [1-(4-oxidanylphenoxy)-1-phosphono-ethyl]phosphonic acid, ...
Authors:Kraft, L.V., Roe, S.M.
Deposit date:2018-05-15
Release date:2018-10-17
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Co-crystallization of human inositol monophosphatase with the lithium mimetic L-690,330.
Acta Crystallogr D Struct Biol, 74, 2018
5MHB
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PRODUCT-COMPLEX OF E.COLI 5-AMINO LAEVULINIC ACID DEHYDRATASE
Descriptor:Delta-aminolevulinic acid dehydratase, 3-[5-(AMINOMETHYL)-4-(CARBOXYMETHYL)-1H-PYRROL-3-YL]PROPANOIC ACID, ZINC ION, ...
Authors:Norton, E., Erskine, P.T., Shoolingin-Jordan, P.M., Cooper, J.B.
Deposit date:2016-11-23
Release date:2016-12-07
Last modified:2017-01-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural studies of substrate and product complexes of 5-aminolaevulinic acid dehydratase from humans, Escherichia coli and the hyperthermophile Pyrobaculum calidifontis.
Acta Crystallogr D Struct Biol, 73, 2017
5LZL
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PYROBACULUM CALIDIFONTIS 5-AMINOLAEVULINIC ACID DEHYDRATASE
Descriptor:Delta-aminolevulinic acid dehydratase, ZINC ION
Authors:Azim, N., Erskine, P.T., Guo, J., Cooper, J.B.
Deposit date:2016-09-30
Release date:2016-10-12
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (3.47 Å)
Cite:Structural studies of substrate and product complexes of 5-aminolaevulinic acid dehydratase from humans, Escherichia coli and the hyperthermophile Pyrobaculum calidifontis.
Acta Crystallogr D Struct Biol, 73, 2017
5HNR
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THE X-RAY STRUCTURE OF OCTAMERIC HUMAN NATIVE 5-AMINOLAEVULINIC ACID DEHYDRATASE.
Descriptor:Delta-aminolevulinic acid dehydratase, ZINC ION, SULFATE ION, ...
Authors:Mills-Davies, N.L., Thompson, D., Shoolingin-Jordan, P.M., Erskine, P.T., Cooper, J.B.
Deposit date:2016-01-18
Release date:2016-01-27
Last modified:2017-01-25
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:Structural studies of substrate and product complexes of 5-aminolaevulinic acid dehydratase from humans, Escherichia coli and the hyperthermophile Pyrobaculum calidifontis.
Acta Crystallogr D Struct Biol, 73, 2017
5HMS
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X-RAY STRUCTURE OF HUMAN RECOMBINANT 5-AMINOLAEVULINIC ACID DEHYDRATASE (HRALAD).
Descriptor:Delta-aminolevulinic acid dehydratase, ZINC ION
Authors:Butler, D., Erskine, P.T., Cooper, J.B., Shoolingin-Jordan, P.M.
Deposit date:2016-01-17
Release date:2016-01-27
Last modified:2017-03-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural studies of substrate and product complexes of 5-aminolaevulinic acid dehydratase from humans, Escherichia coli and the hyperthermophile Pyrobaculum calidifontis.
Acta Crystallogr D Struct Biol, 73, 2017
5CF9
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CLEAVAGE OF NICOTINAMIDE ADENINE DINUCLEOTIDE BY THE RIBOSOME INACTIVATING PROTEIN OF MOMORDICA CHARANTIA - ENZYME-NADP+ CO-CRYSTALLISATION.
Descriptor:Ribosome-inactivating protein momordin I, N-ACETYL-D-GLUCOSAMINE, NICOTINAMIDE
Authors:Vinkovic, M., Wood, S.P., Gill, R., Husain, J., Wood, G.E., Dunn, G.
Deposit date:2015-07-08
Release date:2015-07-22
Last modified:2015-09-09
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Cleavage of nicotinamide adenine dinucleotide by the ribosome-inactivating protein from Momordica charantia.
Acta Crystallogr.,Sect.F, 71, 2015
4YP2
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CLEAVAGE OF NICOTINAMIDE ADENINE DINUCLEOTIDES BY THE RIBOSOME INACTIVATING PROTEIN FROM MOMORDICA CHARANTIA
Descriptor:Ribosome-inactivating protein momordin I, N-ACETYL-D-GLUCOSAMINE, NICOTINAMIDE
Authors:Vinkovic, M., Hussain, J., Wood, G.E., Gill, R., Wood, S.P.
Deposit date:2015-03-12
Release date:2015-05-20
Last modified:2015-09-09
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Cleavage of nicotinamide adenine dinucleotide by the ribosome-inactivating protein from Momordica charantia.
Acta Crystallogr.,Sect.F, 71, 2015
4HTG
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PORPHOBILINOGEN DEAMINASE FROM ARABIDOPSIS THALIANA
Descriptor:Porphobilinogen deaminase, chloroplastic, 3-[(5Z)-5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methylidene}-4-(carboxymethyl)-2-oxo-2,5-dihydro-1H-pyrrol-3-yl]propanoic acid, ...
Authors:Roberts, A., Gill, R., Hussey, R.J., Erskine, P.T., Cooper, J.B., Wood, S.P., Chrystal, E.J.T., Shoolingin-Jordan, P.M.
Deposit date:2012-11-01
Release date:2013-02-27
Last modified:2013-04-03
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Insights into the mechanism of pyrrole polymerization catalysed by porphobilinogen deaminase: high-resolution X-ray studies of the Arabidopsis thaliana enzyme.
Acta Crystallogr.,Sect.D, 69, 2013
3M1O
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HUMAN TRANSTHYRETIN (TTR) COMPLEXED WITH 2-((3,5-DICHLORO-4-HYDROXYPHENYL)AMINO)BENZOIC ACID
Descriptor:Transthyretin, 2-[(3,5-dichloro-4-hydroxyphenyl)amino]benzoic acid
Authors:Kolstoe, S.E., Wood, S.P.
Deposit date:2010-03-05
Release date:2010-11-17
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Trapping of palindromic ligands within native transthyretin prevents amyloid formation.
Proc.Natl.Acad.Sci.USA, 107, 2010
3IPE
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HUMAN TRANSTHYRETIN (TTR) COMPLEXED WITH A PALINDROMIC BIVALENT AMYLOID INHIBITOR (7 CARBON LINKER).
Descriptor:Transthyretin, 2,2'-{heptane-1,7-diylbis[oxy(3,5-dichlorobenzene-4,1-diyl)imino]}dibenzoic acid
Authors:Kolstoe, S.E., Wood, S.P., Pepys, M.B.
Deposit date:2009-08-17
Release date:2010-11-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Trapping of palindromic ligands within native transthyretin prevents amyloid formation.
Proc.Natl.Acad.Sci.USA, 107, 2010
3IPB
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HUMAN TRANSTHYRETIN (TTR) COMPLEXED WITH A PALINDROMIC BIVALENT AMYLOID INHIBITOR (11 CARBON LINKER).
Descriptor:Transthyretin, 2,2'-{undecane-1,11-diylbis[oxy(3,5-dichlorobenzene-4,1-diyl)imino]}dibenzoic acid
Authors:Kolstoe, S.E., Wood, S.P., Pepys, M.B.
Deposit date:2009-08-17
Release date:2010-11-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Trapping of palindromic ligands within native transthyretin prevents amyloid formation.
Proc.Natl.Acad.Sci.USA, 107, 2010
3EQ1
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THE CRYSTAL STRUCTURE OF HUMAN PORPHOBILINOGEN DEAMINASE AT 2.8A RESOLUTION
Descriptor:Porphobilinogen deaminase, 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid, SULFATE ION
Authors:Kolstoe, S.E., Gill, R., Mohammed, F., Wood, S.P.
Deposit date:2008-09-30
Release date:2009-03-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of human porphobilinogen deaminase at 2.8 A: the molecular basis of acute intermittent porphyria
Biochem.J., 420, 2009
2IZP
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BIPD - AN INVASION PRTEIN ASSOCIATED WITH THE TYPE-III SECRETION SYSTEM OF BURKHOLDERIA PSEUDOMALLEI.
Descriptor:PUTATIVE MEMBRANE ANTIGEN
Authors:Erskine, P.T., Knight, M.J., Ruaux, A., Mikolajek, H., Wong-Fat-Sang, N., Withers, J., Gill, R., Wood, S.P., Wood, M., Fox, G.C., Cooper, J.B.
Deposit date:2006-07-25
Release date:2006-09-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:High Resolution Structure of Bipd: An Invasion Protein Associated with the Type III Secretion System of Burkholderia Pseudomallei.
J.Mol.Biol., 363, 2006
2C8S
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CYTOCHROME CL FROM METHYLOBACTERIUM EXTORQUENS
Descriptor:CYTOCHROME C-L, PROTOPORPHYRIN IX CONTAINING FE, CALCIUM ION
Authors:Williams, P.A., Coates, L., Mohammed, F., Gill, R., Erskine, P.T., Wood J, S.P., Cooper, B., Anthony, C.
Deposit date:2005-12-06
Release date:2005-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The 1.6A X-Ray Structure of the Unusual C-Type Cytochrome, Cytochrome Cl, from the Methylotrophic Bacterium Methylobacterium Extorquens.
J.Mol.Biol., 357, 2006
2BJI
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HIGH RESOLUTION STRUCTURE OF MYO-INOSITOL MONOPHOSPHATASE, THE TARGET OF LITHIUM THERAPY
Descriptor:INOSITOL-1(OR 4)-MONOPHOSPHATASE, MAGNESIUM ION
Authors:Gill, R., Mohammed, F., Badyal, R., Coates, L., Erskine, P., Thompson, D., Cooper, J., Gore, M., Wood, S.
Deposit date:2005-02-03
Release date:2005-02-11
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:High-resolution structure of myo-inositol monophosphatase, the putative target of lithium therapy.
Acta Crystallogr. D Biol. Crystallogr., 61, 2005
1W6S
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THE HIGH RESOLUTION STRUCTURE OF METHANOL DEHYDROGENASE FROM METHYLOBACTERIUM EXTORQUENS
Descriptor:METHANOL DEHYDROGENASE SUBUNIT 1, METHANOL DEHYDROGENASE SUBUNIT 2, PYRROLOQUINOLINE QUINONE, ...
Authors:Williams, P.A., Coates, L., Mohammed, F., Gill, R., Erskine, P.T., Wood, S.P., Anthony, C., Cooper, J.B.
Deposit date:2004-08-23
Release date:2004-12-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:The Atomic Resolution Structure of Methanol Dehydrogenase from Methylobacterium Extorquens
Acta Crystallogr.,Sect.D, 61, 2005
1W31
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YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE 5-HYDROXYLAEVULINIC ACID COMPLEX
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE, 5-HYDROXYLAEVULINIC ACID, ZINC ION
Authors:Erskine, P.T., Coates, L., Newbold, R., Brindley, A.A., Stauffer, F., Beaven, G.D.E., Gill, R., Wood, S.P., Warren, M.J., Cooper, J.B., Shoolingin-Jordan, P.M., Neier, R.
Deposit date:2004-07-11
Release date:2005-08-23
Last modified:2014-08-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with the Inhibitor 5-Hydroxylaevulinic Acid
Acta Crystallogr.,Sect.D, 61, 2005
1W1Z
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STRUCTURE OF THE PLANT LIKE 5-AMINOLAEVULINIC ACID DEHYDRATASE FROM CHLOROBIUM VIBRIOFORME
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE, LAEVULINIC ACID, MAGNESIUM ION
Authors:Coates, L., Beaven, G., Erskine, P.T., Beale, S.I., Avissar, Y.J., Gill, R., Mohammed, F., Wood, S.P., Shoolingin-Jordan, P., Cooper, J.B.
Deposit date:2004-06-24
Release date:2004-09-02
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The X-ray structure of the plant like 5-aminolaevulinic acid dehydratase from Chlorobium vibrioforme complexed with the inhibitor laevulinic acid at 2.6 A resolution.
J. Mol. Biol., 342, 2004
1QN2
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CYTOCHROME CH FROM METHYLOBACTERIUM EXTORQUENS
Descriptor:CYTOCHROME CH, HEME C
Authors:Read, J., Gill, R., Dales, S.L., Cooper, J.B., Wood, S.P., Anthony, C.
Deposit date:1999-10-13
Release date:2000-10-13
Last modified:2018-05-30
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:The Molecular Structure of an Unusual Cytochrome C2 Determined at 2.0A; the Cytochrome cH from Methylobacterium Extorquens
Protein Sci., 8, 1999
1H4J
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METHYLOBACTERIUM EXTORQUENS METHANOL DEHYDROGENASE D303E MUTANT
Descriptor:Methanol dehydrogenase [cytochrome c] subunit 1, Methanol dehydrogenase [cytochrome c] subunit 2, PYRROLOQUINOLINE QUINONE, ...
Authors:Mohammed, F., Gill, R., Thompson, D., Cooper, J.B., Wood, S.P., Afolabi, P.R., Anthony, C.
Deposit date:2001-05-11
Release date:2001-08-23
Last modified:2018-09-19
Method:X-RAY DIFFRACTION (3 Å)
Cite:Site-Directed Mutagenesis and X-Ray Crystallography of the Pqq-Containing Quinoprotein Methanol Dehydrogenase and its Electron Acceptor, Cytochrome C(L)(,)
Biochemistry, 40, 2001
1B9G
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INSULIN-LIKE-GROWTH-FACTOR-1
Descriptor:PROTEIN (GROWTH FACTOR IGF-1)
Authors:De Wolf, E., Gill, R., Geddes, S., Pitts, J., Wollmer, A., Grotzinger, J.
Deposit date:1999-02-11
Release date:1999-02-23
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of a mini IGF-1.
Protein Sci., 5, 1996