2OPG | | THE CRYSTAL STRUCTURE OF THE 10TH PDZ DOMAIN OF MPDZ | | Descriptor: | Multiple PDZ domain protein, SODIUM ION | | Authors: | Gileadi, C., Phillips, C., Elkins, J., Papagrigoriou, E., Ugochukwu, E., Gorrec, F., Savitsky, P., Umeano, C., Berridge, G., Gileadi, O., Salah, E., Edwards, A., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC) | | Deposit date: | 2007-01-29 | | Release date: | 2007-02-13 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | The crystal structure of the 10th PDZ domain of MPDZ
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2Q3H | | THE CRYSTAL STRUCTURE OF RHOUA IN THE GDP-BOUND STATE. | | Descriptor: | Ras homolog gene family, member U, MAGNESIUM ION, ... | | Authors: | Gileadi, C., Yang, X., Papagrigoriou, E., Elkins, J., Zhao, Y., Bray, J., Gileadi, O., Umeano, C., Ugochukwu, E., Uppenberg, J., Bunkoczi, G., von Delft, F., Pike, A.C.W., Phillips, C., Savitsky, P., Fedorov, O., Edwards, A., Weigelt, J., Arrowsmith, C.H., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC) | | Deposit date: | 2007-05-30 | | Release date: | 2007-06-19 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.73 Å) | | Cite: | The crystal structure of RhouA in the GDP-bound state.
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2Q3G | | STRUCTURE OF THE PDZ DOMAIN OF HUMAN PDLIM7 BOUND TO A C-TERMINAL EXTENSION FROM HUMAN BETA-TROPOMYOSIN | | Descriptor: | PDZ and LIM domain protein 7, 1,2-ETHANEDIOL, CHLORIDE ION | | Authors: | Gileadi, C., Papagrigoriou, E., Elkins, J., Burgess-Brown, N., Salah, E., Gileadi, O., Umeano, C., Bunkoczi, G., von Delft, F., Uppenberg, J., Pike, A.C.W., Arrowsmith, C.H., Edwards, A., Weigelt, J., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC) | | Deposit date: | 2007-05-30 | | Release date: | 2007-06-19 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.11 Å) | | Cite: | Structure of the PDZ domain of human PDLIM7 bound to a C-terminal extension from human beta-tropomyosin
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2ODE | | CRYSTAL STRUCTURE OF THE HETERODIMERIC COMPLEX OF HUMAN RGS8 AND ACTIVATED GI ALPHA 3 | | Descriptor: | Guanine nucleotide-binding protein G(k) subunit alpha, Regulator of G-protein signaling 8, TETRAFLUOROALUMINATE ION, ... | | Authors: | Gileadi, C., Soundararajan, M., Turnbull, A.P., Elkins, J.M., Papagrigoriou, E., Pike, A.C.W., Bunkoczi, G., Gorrec, F., Umeano, C., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C.H., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC) | | Deposit date: | 2006-12-22 | | Release date: | 2007-02-06 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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2OZF | | THE CRYSTAL STRUCTURE OF THE 2ND PDZ DOMAIN OF THE HUMAN NHERF-1 (SLC9A3R1) | | Descriptor: | Ezrin-radixin-moesin-binding phosphoprotein 50 | | Authors: | Phillips, C., Papagrigoriou, E., Gileadi, C., Fedorov, O., Elkins, J., Berridge, G., Turnbull, A.P., Gileadi, O., Schoch, G., Smee, C., Bray, J., Savitsky, P., Uppenberg, J., von Delft, F., Gorrec, F., Umeano, C., Salah, E., Colebrook, S., Weigelt, J., Arrowsmith, C.H., Edwards, A., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC) | | Deposit date: | 2007-02-26 | | Release date: | 2007-03-13 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | The crystal structure of the 2nd PDZ domain of the human NHERF-1 (SLC9A3R1)
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2OCS | | THE CRYSTAL STRUCTURE OF THE FIRST PDZ DOMAIN OF HUMAN NHERF-2 (SLC9A3R2) | | Descriptor: | Na(+)/H(+) exchange regulatory cofactor NHE-RF2, THIOCYANATE ION, 1,2-ETHANEDIOL | | Authors: | Papagrigoriou, E., Phillips, C., Gileadi, C., Elkins, J., Salah, E., Berridge, G., Savitsky, P., Gorrec, F., Umeano, C., Ugochukwu, E., Gileadi, O., Burgess, N., Edwards, A., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC) | | Deposit date: | 2006-12-21 | | Release date: | 2007-01-16 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | The crystal structure of the first PDZ domain of human NHERF-2 (SLC9A3R2)
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2P0A | | THE CRYSTAL STRUCTURE OF HUMAN SYNAPSIN III (SYN3) IN COMPLEX WITH AMPPNP | | Descriptor: | Synapsin-3, CHLORIDE ION, SULFATE ION, ... | | Authors: | Turnbull, A.P., Phillips, C., Pike, A.C.W., Elkins, J.M., Gileadi, C., Salah, E., Niesen, F.H., Burgess, N., Gileadi, O., Gorrec, F., Umeano, C., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C.H., Sundstrom, M., Doyle, D., Structural Genomics Consortium (SGC) | | Deposit date: | 2007-02-28 | | Release date: | 2007-03-27 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The crystal structure of human synapsin III (SYN3) in complex with AMPPNP
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2PNT | | CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF HUMAN GRASP (GRP1) IN COMPLEX WITH THE C-TERMINAL PEPTIDE OF THE METABOTROPIC GLUTAMATE RECEPTOR TYPE 1 | | Descriptor: | General receptor for phosphoinositides 1-associated scaffold protein, CHLORIDE ION | | Authors: | Elkins, J., Papagrigoriou, E., Cooper, C., Gileadi, C., Uppenberg, J., Bray, J., von Delft, F., Pike, A.C.W., Ugochukwu, E., Umeano, C., Gileadi, O., Edwards, A., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC) | | Deposit date: | 2007-04-25 | | Release date: | 2007-05-08 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (2.148 Å) | | Cite: | Crystal structure of the PDZ domain of human GRASP (GRP1) in complex with the C-terminal peptide of the metabotropic glutamate receptor type 1.
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2C2H | | CRYSTAL STRUCTURE OF THE HUMAN RAC3 IN COMPLEX WITH GDP | | Descriptor: | RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 3, GUANOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... | | Authors: | Debreczeni, J.E., Yang, X., Zao, Y., Elkins, J., Gileadi, C., Burgess, N., Colebrook, S., Gileadi, O., Fedorov, O., Bunkoczi, G., von Delft, F., Doyle, D., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A. | | Deposit date: | 2005-09-29 | | Release date: | 2005-10-13 | | Last modified: | 2018-02-28 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Crystal Structure of the Human Rac3 in Complex with Gdp
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2ERY | | THE CRYSTAL STRUCTURE OF THE RAS RELATED PROTEIN RRAS2 (RRAS2) IN THE GDP BOUND STATE | | Descriptor: | Ras-related protein R-Ras2, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE | | Authors: | Salah, E., Schoch, G., Turnbull, A., Papagrigoriou, E., Soundararajan, M., Burgess, N., Elkins, J., Gileadi, C., Gileadi, O., von Delft, F., Edwards, A., Arrowsmith, C., Weigelt, J., Sundstrom, M., Doyle, D., Structural Genomics Consortium (SGC) | | Deposit date: | 2005-10-25 | | Release date: | 2005-11-08 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The crystal structure of the Ras related protein RRas2 (RRAS2) in the GDP bound state
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2G0N | | THE CRYSTAL STRUCTURE OF THE HUMAN RAC3 IN COMPLEX WITH GDP AND CHLORIDE | | Descriptor: | Ras-related C3 botulinum toxin substrate 3, MAGNESIUM ION, CHLORIDE ION, ... | | Authors: | Ugochukwu, E., Yang, X., Zao, Y., Elkins, J., Gileadi, C., Burgess, N., Colebrook, S., Gileadi, O., Fedorov, O., Bunkoczi, G., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., von Delft, F., Doyle, D., Structural Genomics Consortium (SGC) | | Deposit date: | 2006-02-13 | | Release date: | 2006-05-30 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The Crystal Structure of the Human RAC3 in complex with GDP and Chloride
To be Published
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2PKT | | CRYSTAL STRUCTURE OF THE HUMAN CLP-36 (PDLIM1) BOUND TO THE C-TERMINAL PEPTIDE OF HUMAN ALPHA-ACTININ-1 | | Descriptor: | PDZ and LIM domain protein 1, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Uppenberg, J., Gileadi, C., Elkins, J., Bray, J., Burgess-Brown, N., Salah, E., Gileadi, O., Bunkoczi, G., Ugochukwu, E., Umeano, C., von Delft, F., Weigelt, J., Arrowsmith, C.H., Edwards, A., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC) | | Deposit date: | 2007-04-18 | | Release date: | 2007-05-08 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | The crystal structure of the human CLP-36 (PDLIM1) bound to the C-terminal peptide of human alpha-actinin-1.
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2REY | | CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF HUMAN DISHEVELLED 2 (HOMOLOGOUS TO DROSOPHILA DSH) | | Descriptor: | Segment polarity protein dishevelled homolog DVL-2 | | Authors: | Papagrigoriou, E., Gileadi, C., Elkins, J., Cooper, C., Ugochukwu, E., Turnbull, A., Pike, A.C.W., Gileadi, O., von Delft, F., Sundstrom, M., Arrowsmith, C.H., Weigelt, J., Edwards, A.M., Doyle, D., Structural Genomics Consortium (SGC) | | Deposit date: | 2007-09-27 | | Release date: | 2007-10-23 | | Last modified: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Crystal structure of the PDZ domains of human dishevelled 2 (homologous to Drosophila dsh).
To be Published
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3ZWF | | CRYSTAL STRUCTURE OF HUMAN TRNASE Z, SHORT FORM (ELAC1). | | Descriptor: | ZINC PHOSPHODIESTERASE ELAC PROTEIN 1, 1,2-ETHANEDIOL, ZINC ION, ... | | Authors: | Allerston, C.K., Krojer, T., Berridge, G., Burgess-Brown, N., Chaikuad, A., Chalk, R., Elkins, J.M., Gileadi, C., Latwiel, S.V.A., Savitsky, P., Vollmar, M., Arrowsmith, C.H., Weigelt, J., Edwards, A., Bountra, C., von Delft, F., Gileadi, O. | | Deposit date: | 2011-07-29 | | Release date: | 2011-08-10 | | Last modified: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal Structure of Human Trnase Z, Short Form (Elac1).
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2IHD | | CRYSTAL STRUCTURE OF HUMAN REGULATOR OF G-PROTEIN SIGNALING 8, RGS8 | | Descriptor: | Regulator of G-protein signaling 8, CHLORIDE ION | | Authors: | Turnbull, A.P., Papagrigoriou, E., Ugochukwu, E., Salah, E., Gileadi, C., Burgess, N., Bhatia, C., Gileadi, O., Bray, J., Elkins, J., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC) | | Deposit date: | 2006-09-26 | | Release date: | 2006-11-21 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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2XDP | | CRYSTAL STRUCTURE OF THE TUDOR DOMAIN OF HUMAN JMJD2C | | Descriptor: | LYSINE-SPECIFIC DEMETHYLASE 4C, SULFATE ION | | Authors: | Yue, W.W., Gileadi, C., Krojer, T., Weisbach, H., Ugochukwu, E., Daniel, M., Phillips, C., Chaikuad, A., von Delft, F., Allerston, C., Arrowsmith, C., Weigelt, J., Edwards, A., Bountra, C., Oppermann, U. | | Deposit date: | 2010-05-06 | | Release date: | 2010-06-09 | | Last modified: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (1.56 Å) | | Cite: | Crystal Structure of the Tudor Domain of Human Jmjd2C
To be Published
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2FCF | | THE CRYSTAL STRUCTURE OF THE 7TH PDZ DOMAIN OF MPDZ (MUPP-1) | | Descriptor: | Multiple PDZ domain protein | | Authors: | Papagrigoriou, E., Berridge, G., Johansson, C., Colebrook, S., Salah, E., Burgess, N., Smee, C., Savitsky, P., Bray, J., Schoch, G., Phillips, C., Gileadi, C., Soundarajan, M., Yang, X., Elkins, J.M., Gorrec, F., Turnbull, A., Edwards, A., Arrowsmith, C., Weigelt, J., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC) | | Deposit date: | 2005-12-12 | | Release date: | 2006-01-17 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.76 Å) | | Cite: | Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.
Protein Sci., 16, 2007
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2FNE | | THE CRYSTAL STRUCTURE OF THE 13TH PDZ DOMAIN OF MPDZ | | Descriptor: | Multiple PDZ domain protein | | Authors: | Papagrigoriou, E., Berridge, G., Johansson, C., Colebrook, S., Salah, E., Burgess, N., Smee, C., Savitsky, P., Bray, J., Schoch, G., Phillips, C., Gileadi, C., Soundarajan, M., Yang, X., Elkins, J.M., Gorrec, F., Turnbull, A., Edwards, A., Arrowsmith, C., Weigelt, J., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC) | | Deposit date: | 2006-01-11 | | Release date: | 2006-01-24 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.83 Å) | | Cite: | Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.
Protein Sci., 16, 2007
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2J1L | | CRYSTAL STRUCTURE OF HUMAN RHO-RELATED GTP-BINDING PROTEIN RHOD | | Descriptor: | RHO-RELATED GTP-BINDING PROTEIN RHOD, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | | Authors: | Pike, A.C.W., Johansson, C., Gileadi, C., Niesen, F.H., Sobott, F., Schoch, G., Elkins, J., Smee, C., Gorrec, F., Watt, S., Bray, J., Turnbull, A.P., von Delft, F., Arrowsmith, C., Edwards, A., Weigelt, J., Sundstrom, M., Doyle, D. | | Deposit date: | 2006-08-14 | | Release date: | 2006-09-18 | | Last modified: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal Structure of Human Rho-Related GTP-Binding Protein Rhod
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2O2T | | THE CRYSTAL STRUCTURE OF THE 1ST PDZ DOMAIN OF MPDZ | | Descriptor: | Multiple PDZ domain protein | | Authors: | Papagrigoriou, E., Gileadi, C., Phillips, C., Johansson, C., Salah, E., Savitsky, P., Gorrec, F., Umeano, C., Berridge, G., Pike, A.C.W., Elkins, J., Edwards, A., Arrowsmith, C., Weigelt, J., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC) | | Deposit date: | 2006-11-30 | | Release date: | 2006-12-12 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | The crystal structure of the 1st PDZ domain of MPDZ
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2V90 | | CRYSTAL STRUCTURE OF THE 3RD PDZ DOMAIN OF INTESTINE- AND KIDNEY- ENRICHED PDZ DOMAIN IKEPP (PDZD3) | | Descriptor: | PDZ DOMAIN-CONTAINING PROTEIN 3, SULFATE ION | | Authors: | Uppenberg, J., Gileadi, C., Phillips, C., Elkins, J., Bunkoczi, G., Cooper, C., Pike, A.C.W., Salah, E., Ugochukwu, E., Arrowsmith, C.H., Edwards, A., Sundstrom, M., Weigelt, J., Doyle, D.A. | | Deposit date: | 2007-08-16 | | Release date: | 2007-08-28 | | Last modified: | 2018-02-28 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal Structure of the 3Rd Pdz Domain of Intestine- and Kidney-Enriched Pdz Domain Ikepp (Pdzd3)
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2X4D | | CRYSTAL STRUCTURE OF HUMAN PHOSPHOLYSINE PHOSPHOHISTIDINE INORGANIC PYROPHOSPHATE PHOSPHATASE LHPP | | Descriptor: | PHOSPHOLYSINE PHOSPHOHISTIDINE INORGANIC PYROPHOSPHATE PHOSPHATASE, PYROPHOSPHATE 2-, MAGNESIUM ION, ... | | Authors: | Vollmar, M., Gileadi, C., Guo, K., Savitsky, P., Muniz, J.R.C., Yue, W., Allerston, C., von Delft, F., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., Kavanagh, K.L., Oppermann, U. | | Deposit date: | 2010-01-29 | | Release date: | 2010-03-16 | | Last modified: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | Crystal Structure of Human Phospholysine Phosphohistidine Inorganic Pyrophosphate Phosphatase Lhpp
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2XST | | CRYSTAL STRUCTURE OF THE HUMAN LIPOCALIN 15 | | Descriptor: | LIPOCALIN 15, 1,2-ETHANEDIOL | | Authors: | Muniz, J.R.C., Gileadi, C., Yue, W.W., Krojer, T., Ugochukwu, E., Phillips, C., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Kavanagh, K.L., Oppermann, U. | | Deposit date: | 2010-09-30 | | Release date: | 2010-10-13 | | Last modified: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (1.63 Å) | | Cite: | Crystal Structure of the Human Lipocalin 15
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4C8D | | CRYSTAL STRUCTURE OF JMJC DOMAIN OF HUMAN HISTONE 3 LYSINE-SPECIFIC DEMETHYLASE 3B (KDM3B) | | Descriptor: | LYSINE-SPECIFIC DEMETHYLASE 3B, MANGANESE (II) ION, N-OXALYLGLYCINE, ... | | Authors: | Vollmar, M., Johansson, C., Gileadi, C., Goubin, S., Szykowska, A., Krojer, T., Crawley, L., von Delft, F., Arrowsmith, C.H., Bountra, C., Edwards, A., Oppermann, U. | | Deposit date: | 2013-09-30 | | Release date: | 2013-10-16 | | Last modified: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (2.18 Å) | | Cite: | Crystal Structure of Jmjc Domain of Human Histone 3 Lysine-Specific Demethylase 3B (Kdm3B)
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4D6Q | | CRYSTAL STRUCTURE OF HUMAN JMJD2D IN COMPLEX WITH 2,4-PDCA | | Descriptor: | LYSINE-SPECIFIC DEMETHYLASE 4D, ZINC ION, NICKEL (II) ION, ... | | Authors: | Krojer, T., Vollmar, M., Bradley, A., Crawley, L., Szykowska, A., Burgess-Brown, N., Gileadi, C., Johansson, C., Oppermann, U., Bountra, C., Arrowsmith, C.H., Edwards, A., von Delft, F. | | Deposit date: | 2014-11-14 | | Release date: | 2014-12-24 | | Last modified: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (1.292 Å) | | Cite: | Crystal Structure of Human Jmjd2D in Complex with 2,4-Pdca
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