Author results

2OPG
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THE CRYSTAL STRUCTURE OF THE 10TH PDZ DOMAIN OF MPDZ
Descriptor:Multiple PDZ domain protein, SODIUM ION
Authors:Gileadi, C., Phillips, C., Elkins, J., Papagrigoriou, E., Ugochukwu, E., Gorrec, F., Savitsky, P., Umeano, C., Berridge, G., Gileadi, O., Salah, E., Edwards, A., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
Deposit date:2007-01-29
Release date:2007-02-13
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The crystal structure of the 10th PDZ domain of MPDZ
To be Published
2Q3H
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THE CRYSTAL STRUCTURE OF RHOUA IN THE GDP-BOUND STATE.
Descriptor:Ras homolog gene family, member U, MAGNESIUM ION, ...
Authors:Gileadi, C., Yang, X., Papagrigoriou, E., Elkins, J., Zhao, Y., Bray, J., Gileadi, O., Umeano, C., Ugochukwu, E., Uppenberg, J., Bunkoczi, G., von Delft, F., Pike, A.C.W., Phillips, C., Savitsky, P., Fedorov, O., Edwards, A., Weigelt, J., Arrowsmith, C.H., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
Deposit date:2007-05-30
Release date:2007-06-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:The crystal structure of RhouA in the GDP-bound state.
To be Published
2Q3G
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STRUCTURE OF THE PDZ DOMAIN OF HUMAN PDLIM7 BOUND TO A C-TERMINAL EXTENSION FROM HUMAN BETA-TROPOMYOSIN
Descriptor:PDZ and LIM domain protein 7, 1,2-ETHANEDIOL, CHLORIDE ION
Authors:Gileadi, C., Papagrigoriou, E., Elkins, J., Burgess-Brown, N., Salah, E., Gileadi, O., Umeano, C., Bunkoczi, G., von Delft, F., Uppenberg, J., Pike, A.C.W., Arrowsmith, C.H., Edwards, A., Weigelt, J., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
Deposit date:2007-05-30
Release date:2007-06-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.11 Å)
Cite:Structure of the PDZ domain of human PDLIM7 bound to a C-terminal extension from human beta-tropomyosin
To be Published
2ODE
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CRYSTAL STRUCTURE OF THE HETERODIMERIC COMPLEX OF HUMAN RGS8 AND ACTIVATED GI ALPHA 3
Descriptor:Guanine nucleotide-binding protein G(k) subunit alpha, Regulator of G-protein signaling 8, TETRAFLUOROALUMINATE ION, ...
Authors:Gileadi, C., Soundararajan, M., Turnbull, A.P., Elkins, J.M., Papagrigoriou, E., Pike, A.C.W., Bunkoczi, G., Gorrec, F., Umeano, C., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C.H., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
Deposit date:2006-12-22
Release date:2007-02-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2OZF
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THE CRYSTAL STRUCTURE OF THE 2ND PDZ DOMAIN OF THE HUMAN NHERF-1 (SLC9A3R1)
Descriptor:Ezrin-radixin-moesin-binding phosphoprotein 50
Authors:Phillips, C., Papagrigoriou, E., Gileadi, C., Fedorov, O., Elkins, J., Berridge, G., Turnbull, A.P., Gileadi, O., Schoch, G., Smee, C., Bray, J., Savitsky, P., Uppenberg, J., von Delft, F., Gorrec, F., Umeano, C., Salah, E., Colebrook, S., Weigelt, J., Arrowsmith, C.H., Edwards, A., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
Deposit date:2007-02-26
Release date:2007-03-13
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The crystal structure of the 2nd PDZ domain of the human NHERF-1 (SLC9A3R1)
To be Published
2OCS
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THE CRYSTAL STRUCTURE OF THE FIRST PDZ DOMAIN OF HUMAN NHERF-2 (SLC9A3R2)
Descriptor:Na(+)/H(+) exchange regulatory cofactor NHE-RF2, THIOCYANATE ION, 1,2-ETHANEDIOL
Authors:Papagrigoriou, E., Phillips, C., Gileadi, C., Elkins, J., Salah, E., Berridge, G., Savitsky, P., Gorrec, F., Umeano, C., Ugochukwu, E., Gileadi, O., Burgess, N., Edwards, A., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
Deposit date:2006-12-21
Release date:2007-01-16
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The crystal structure of the first PDZ domain of human NHERF-2 (SLC9A3R2)
To be Published
2P0A
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THE CRYSTAL STRUCTURE OF HUMAN SYNAPSIN III (SYN3) IN COMPLEX WITH AMPPNP
Descriptor:Synapsin-3, CHLORIDE ION, SULFATE ION, ...
Authors:Turnbull, A.P., Phillips, C., Pike, A.C.W., Elkins, J.M., Gileadi, C., Salah, E., Niesen, F.H., Burgess, N., Gileadi, O., Gorrec, F., Umeano, C., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C.H., Sundstrom, M., Doyle, D., Structural Genomics Consortium (SGC)
Deposit date:2007-02-28
Release date:2007-03-27
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The crystal structure of human synapsin III (SYN3) in complex with AMPPNP
To be Published
2PNT
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CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF HUMAN GRASP (GRP1) IN COMPLEX WITH THE C-TERMINAL PEPTIDE OF THE METABOTROPIC GLUTAMATE RECEPTOR TYPE 1
Descriptor:General receptor for phosphoinositides 1-associated scaffold protein, CHLORIDE ION
Authors:Elkins, J., Papagrigoriou, E., Cooper, C., Gileadi, C., Uppenberg, J., Bray, J., von Delft, F., Pike, A.C.W., Ugochukwu, E., Umeano, C., Gileadi, O., Edwards, A., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
Deposit date:2007-04-25
Release date:2007-05-08
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.148 Å)
Cite:Crystal structure of the PDZ domain of human GRASP (GRP1) in complex with the C-terminal peptide of the metabotropic glutamate receptor type 1.
To be Published
2C2H
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CRYSTAL STRUCTURE OF THE HUMAN RAC3 IN COMPLEX WITH GDP
Descriptor:RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 3, GUANOSINE-5'-DIPHOSPHATE, CALCIUM ION, ...
Authors:Debreczeni, J.E., Yang, X., Zao, Y., Elkins, J., Gileadi, C., Burgess, N., Colebrook, S., Gileadi, O., Fedorov, O., Bunkoczi, G., von Delft, F., Doyle, D., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A.
Deposit date:2005-09-29
Release date:2005-10-13
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structure of the Human Rac3 in Complex with Gdp
To be Published
2ERY
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THE CRYSTAL STRUCTURE OF THE RAS RELATED PROTEIN RRAS2 (RRAS2) IN THE GDP BOUND STATE
Descriptor:Ras-related protein R-Ras2, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Salah, E., Schoch, G., Turnbull, A., Papagrigoriou, E., Soundararajan, M., Burgess, N., Elkins, J., Gileadi, C., Gileadi, O., von Delft, F., Edwards, A., Arrowsmith, C., Weigelt, J., Sundstrom, M., Doyle, D., Structural Genomics Consortium (SGC)
Deposit date:2005-10-25
Release date:2005-11-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The crystal structure of the Ras related protein RRas2 (RRAS2) in the GDP bound state
To be Published
2G0N
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THE CRYSTAL STRUCTURE OF THE HUMAN RAC3 IN COMPLEX WITH GDP AND CHLORIDE
Descriptor:Ras-related C3 botulinum toxin substrate 3, MAGNESIUM ION, CHLORIDE ION, ...
Authors:Ugochukwu, E., Yang, X., Zao, Y., Elkins, J., Gileadi, C., Burgess, N., Colebrook, S., Gileadi, O., Fedorov, O., Bunkoczi, G., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., von Delft, F., Doyle, D., Structural Genomics Consortium (SGC)
Deposit date:2006-02-13
Release date:2006-05-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Crystal Structure of the Human RAC3 in complex with GDP and Chloride
To be Published
2PKT
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CRYSTAL STRUCTURE OF THE HUMAN CLP-36 (PDLIM1) BOUND TO THE C-TERMINAL PEPTIDE OF HUMAN ALPHA-ACTININ-1
Descriptor:PDZ and LIM domain protein 1, CALCIUM ION, CHLORIDE ION, ...
Authors:Uppenberg, J., Gileadi, C., Elkins, J., Bray, J., Burgess-Brown, N., Salah, E., Gileadi, O., Bunkoczi, G., Ugochukwu, E., Umeano, C., von Delft, F., Weigelt, J., Arrowsmith, C.H., Edwards, A., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
Deposit date:2007-04-18
Release date:2007-05-08
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The crystal structure of the human CLP-36 (PDLIM1) bound to the C-terminal peptide of human alpha-actinin-1.
To be Published
2REY
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CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF HUMAN DISHEVELLED 2 (HOMOLOGOUS TO DROSOPHILA DSH)
Descriptor:Segment polarity protein dishevelled homolog DVL-2
Authors:Papagrigoriou, E., Gileadi, C., Elkins, J., Cooper, C., Ugochukwu, E., Turnbull, A., Pike, A.C.W., Gileadi, O., von Delft, F., Sundstrom, M., Arrowsmith, C.H., Weigelt, J., Edwards, A.M., Doyle, D., Structural Genomics Consortium (SGC)
Deposit date:2007-09-27
Release date:2007-10-23
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structure of the PDZ domains of human dishevelled 2 (homologous to Drosophila dsh).
To be Published
3ZWF
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CRYSTAL STRUCTURE OF HUMAN TRNASE Z, SHORT FORM (ELAC1).
Descriptor:ZINC PHOSPHODIESTERASE ELAC PROTEIN 1, 1,2-ETHANEDIOL, ZINC ION, ...
Authors:Allerston, C.K., Krojer, T., Berridge, G., Burgess-Brown, N., Chaikuad, A., Chalk, R., Elkins, J.M., Gileadi, C., Latwiel, S.V.A., Savitsky, P., Vollmar, M., Arrowsmith, C.H., Weigelt, J., Edwards, A., Bountra, C., von Delft, F., Gileadi, O.
Deposit date:2011-07-29
Release date:2011-08-10
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of Human Trnase Z, Short Form (Elac1).
To be Published
2IHD
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CRYSTAL STRUCTURE OF HUMAN REGULATOR OF G-PROTEIN SIGNALING 8, RGS8
Descriptor:Regulator of G-protein signaling 8, CHLORIDE ION
Authors:Turnbull, A.P., Papagrigoriou, E., Ugochukwu, E., Salah, E., Gileadi, C., Burgess, N., Bhatia, C., Gileadi, O., Bray, J., Elkins, J., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
Deposit date:2006-09-26
Release date:2006-11-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2XDP
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CRYSTAL STRUCTURE OF THE TUDOR DOMAIN OF HUMAN JMJD2C
Descriptor:LYSINE-SPECIFIC DEMETHYLASE 4C, SULFATE ION
Authors:Yue, W.W., Gileadi, C., Krojer, T., Weisbach, H., Ugochukwu, E., Daniel, M., Phillips, C., Chaikuad, A., von Delft, F., Allerston, C., Arrowsmith, C., Weigelt, J., Edwards, A., Bountra, C., Oppermann, U.
Deposit date:2010-05-06
Release date:2010-06-09
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Crystal Structure of the Tudor Domain of Human Jmjd2C
To be Published
2FCF
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THE CRYSTAL STRUCTURE OF THE 7TH PDZ DOMAIN OF MPDZ (MUPP-1)
Descriptor:Multiple PDZ domain protein
Authors:Papagrigoriou, E., Berridge, G., Johansson, C., Colebrook, S., Salah, E., Burgess, N., Smee, C., Savitsky, P., Bray, J., Schoch, G., Phillips, C., Gileadi, C., Soundarajan, M., Yang, X., Elkins, J.M., Gorrec, F., Turnbull, A., Edwards, A., Arrowsmith, C., Weigelt, J., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
Deposit date:2005-12-12
Release date:2006-01-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.
Protein Sci., 16, 2007
2FNE
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THE CRYSTAL STRUCTURE OF THE 13TH PDZ DOMAIN OF MPDZ
Descriptor:Multiple PDZ domain protein
Authors:Papagrigoriou, E., Berridge, G., Johansson, C., Colebrook, S., Salah, E., Burgess, N., Smee, C., Savitsky, P., Bray, J., Schoch, G., Phillips, C., Gileadi, C., Soundarajan, M., Yang, X., Elkins, J.M., Gorrec, F., Turnbull, A., Edwards, A., Arrowsmith, C., Weigelt, J., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
Deposit date:2006-01-11
Release date:2006-01-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.
Protein Sci., 16, 2007
2J1L
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CRYSTAL STRUCTURE OF HUMAN RHO-RELATED GTP-BINDING PROTEIN RHOD
Descriptor:RHO-RELATED GTP-BINDING PROTEIN RHOD, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Pike, A.C.W., Johansson, C., Gileadi, C., Niesen, F.H., Sobott, F., Schoch, G., Elkins, J., Smee, C., Gorrec, F., Watt, S., Bray, J., Turnbull, A.P., von Delft, F., Arrowsmith, C., Edwards, A., Weigelt, J., Sundstrom, M., Doyle, D.
Deposit date:2006-08-14
Release date:2006-09-18
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of Human Rho-Related GTP-Binding Protein Rhod
To be Published
2O2T
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THE CRYSTAL STRUCTURE OF THE 1ST PDZ DOMAIN OF MPDZ
Descriptor:Multiple PDZ domain protein
Authors:Papagrigoriou, E., Gileadi, C., Phillips, C., Johansson, C., Salah, E., Savitsky, P., Gorrec, F., Umeano, C., Berridge, G., Pike, A.C.W., Elkins, J., Edwards, A., Arrowsmith, C., Weigelt, J., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
Deposit date:2006-11-30
Release date:2006-12-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The crystal structure of the 1st PDZ domain of MPDZ
To be Published
2V90
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CRYSTAL STRUCTURE OF THE 3RD PDZ DOMAIN OF INTESTINE- AND KIDNEY- ENRICHED PDZ DOMAIN IKEPP (PDZD3)
Descriptor:PDZ DOMAIN-CONTAINING PROTEIN 3, SULFATE ION
Authors:Uppenberg, J., Gileadi, C., Phillips, C., Elkins, J., Bunkoczi, G., Cooper, C., Pike, A.C.W., Salah, E., Ugochukwu, E., Arrowsmith, C.H., Edwards, A., Sundstrom, M., Weigelt, J., Doyle, D.A.
Deposit date:2007-08-16
Release date:2007-08-28
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of the 3Rd Pdz Domain of Intestine- and Kidney-Enriched Pdz Domain Ikepp (Pdzd3)
To be Published
2X4D
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CRYSTAL STRUCTURE OF HUMAN PHOSPHOLYSINE PHOSPHOHISTIDINE INORGANIC PYROPHOSPHATE PHOSPHATASE LHPP
Descriptor:PHOSPHOLYSINE PHOSPHOHISTIDINE INORGANIC PYROPHOSPHATE PHOSPHATASE, PYROPHOSPHATE 2-, MAGNESIUM ION, ...
Authors:Vollmar, M., Gileadi, C., Guo, K., Savitsky, P., Muniz, J.R.C., Yue, W., Allerston, C., von Delft, F., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., Kavanagh, K.L., Oppermann, U.
Deposit date:2010-01-29
Release date:2010-03-16
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Crystal Structure of Human Phospholysine Phosphohistidine Inorganic Pyrophosphate Phosphatase Lhpp
To be Published
2XST
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CRYSTAL STRUCTURE OF THE HUMAN LIPOCALIN 15
Descriptor:LIPOCALIN 15, 1,2-ETHANEDIOL
Authors:Muniz, J.R.C., Gileadi, C., Yue, W.W., Krojer, T., Ugochukwu, E., Phillips, C., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Kavanagh, K.L., Oppermann, U.
Deposit date:2010-09-30
Release date:2010-10-13
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Crystal Structure of the Human Lipocalin 15
To be Published
4C8D
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CRYSTAL STRUCTURE OF JMJC DOMAIN OF HUMAN HISTONE 3 LYSINE-SPECIFIC DEMETHYLASE 3B (KDM3B)
Descriptor:LYSINE-SPECIFIC DEMETHYLASE 3B, MANGANESE (II) ION, N-OXALYLGLYCINE, ...
Authors:Vollmar, M., Johansson, C., Gileadi, C., Goubin, S., Szykowska, A., Krojer, T., Crawley, L., von Delft, F., Arrowsmith, C.H., Bountra, C., Edwards, A., Oppermann, U.
Deposit date:2013-09-30
Release date:2013-10-16
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Crystal Structure of Jmjc Domain of Human Histone 3 Lysine-Specific Demethylase 3B (Kdm3B)
To be Published
4D6Q
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CRYSTAL STRUCTURE OF HUMAN JMJD2D IN COMPLEX WITH 2,4-PDCA
Descriptor:LYSINE-SPECIFIC DEMETHYLASE 4D, ZINC ION, NICKEL (II) ION, ...
Authors:Krojer, T., Vollmar, M., Bradley, A., Crawley, L., Szykowska, A., Burgess-Brown, N., Gileadi, C., Johansson, C., Oppermann, U., Bountra, C., Arrowsmith, C.H., Edwards, A., von Delft, F.
Deposit date:2014-11-14
Release date:2014-12-24
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.292 Å)
Cite:Crystal Structure of Human Jmjd2D in Complex with 2,4-Pdca
To be Published
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