2VP8
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![BU of 2vp8 by Molmil](/molmil-images/mine/2vp8) | Structure of Mycobacterium tuberculosis Rv1207 | Descriptor: | 1,2-ETHANEDIOL, DIHYDROPTEROATE SYNTHASE 2 | Authors: | Gengenbacher, M, Xu, T, Niyomwattanakit, P, Spraggon, G, Dick, T. | Deposit date: | 2008-02-27 | Release date: | 2008-08-12 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.64 Å) | Cite: | Biochemical and Structural Characterization of the Putative Dihydropteroate Synthase Ortholog Rv1207 of Mycobacterium Tuberculosis. Fems Microbiol.Lett., 287, 2008
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2ABW
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![BU of 2abw by Molmil](/molmil-images/mine/2abw) | Glutaminase subunit of the plasmodial PLP synthase (Vitamin B6 biosynthesis) | Descriptor: | Pdx2 protein, TETRAETHYLENE GLYCOL | Authors: | Gengenbacher, M, Fitzpatrick, T.B, Raschle, T, Flicker, K, Sinning, I, Mueller, S, Macheroux, P, Tews, I, Kappes, B. | Deposit date: | 2005-07-17 | Release date: | 2006-01-10 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Vitamin B6 Biosynthesis by the Malaria Parasite Plasmodium falciparum: Biochemical and structural insights J.Biol.Chem., 281, 2006
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7U22
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![BU of 7u22 by Molmil](/molmil-images/mine/7u22) | Mycobacterium tuberculosis RNA polymerase sigma A holoenzyme open promoter complex containing UMN-7 | Descriptor: | (9S,14S,15R,16S,17R,18R,19R,20S,21S,25R)-5,6,18,20-tetrahydroxy-14-methoxy-7,9,15,17,19,21,25-heptamethyl-1'-(2-methylpropyl)-10,26-dioxo-1,3,9,10-tetrahydrospiro[9,4-(epoxypentadecanoimino)furo[2',3':7,8]naphtho[1,2-d]imidazole-2,4'-piperidin]-16-yl benzoate, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Molodtsov, V, Ebright, R.H. | Deposit date: | 2022-02-22 | Release date: | 2022-10-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.87 Å) | Cite: | Redesign of Rifamycin Antibiotics to Overcome ADP-Ribosylation-Mediated Resistance. Angew.Chem.Int.Ed.Engl., 61, 2022
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7KL8
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![BU of 7kl8 by Molmil](/molmil-images/mine/7kl8) | Structure of F420 binding protein Rv1558 from Mycobacterium tuberculosis with F420 bound | Descriptor: | COENZYME F420, COENZYME F420-3, Deazaflavin-dependent nitroreductase, ... | Authors: | Lee, B.M, Tan, L.L, Jackson, C.J. | Deposit date: | 2020-10-29 | Release date: | 2021-03-24 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.469 Å) | Cite: | Potency boost of a Mycobacterium tuberculosis dihydrofolate reductase inhibitor by multienzyme F 420 H 2 -dependent reduction. Proc.Natl.Acad.Sci.USA, 118, 2021
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8TQG
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![BU of 8tqg by Molmil](/molmil-images/mine/8tqg) | |
8TQV
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![BU of 8tqv by Molmil](/molmil-images/mine/8tqv) | |
8TR4
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![BU of 8tr4 by Molmil](/molmil-images/mine/8tr4) | Crystal Structure of Mtb Pks13 Thioesterase domain in complex with inhibitor X20404 | Descriptor: | 4-(2-{(4M)-4-[(6M)-6-(2,5-dimethoxyphenyl)pyridin-3-yl]-1H-1,2,3-triazol-1-yl}ethyl)-N,N-dimethylbenzamide, Polyketide synthase Pks13, SULFATE ION | Authors: | Krieger, I.V, Sacchettini, J.C. | Deposit date: | 2023-08-09 | Release date: | 2024-04-24 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Inhibitors of the Thioesterase Activity of Mycobacterium tuberculosis Pks13 Discovered Using DNA-Encoded Chemical Library Screening. Acs Infect Dis., 2024
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8TRY
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![BU of 8try by Molmil](/molmil-images/mine/8try) | |
4ADU
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![BU of 4adu by Molmil](/molmil-images/mine/4adu) | Crystal structure of plasmodial PLP synthase with bound R5P intermediate | Descriptor: | 1,2-ETHANEDIOL, PYRIDOXINE BIOSYNTHETIC ENZYME PDX1 HOMOLOGUE, PUTATIVE, ... | Authors: | Guedez, G, Sinning, I, Tews, I. | Deposit date: | 2012-01-03 | Release date: | 2012-01-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | Assembly of the Eukaryotic Plp-Synthase Complex from Plasmodium and Activation of the Pdx1 Enzyme. Structure, 20, 2012
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4ADS
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![BU of 4ads by Molmil](/molmil-images/mine/4ads) | Crystal structure of plasmodial PLP synthase complex | Descriptor: | PDX2 PROTEIN, PHOSPHATE ION, PYRIDOXINE BIOSYNTHETIC ENZYME PDX1 HOMOLOGUE, ... | Authors: | Guedez, G, Sinning, I, Tews, I. | Deposit date: | 2012-01-03 | Release date: | 2012-01-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.61 Å) | Cite: | Assembly of the Eukaryotic Plp-Synthase Complex from Plasmodium and Activation of the Pdx1 Enzyme. Structure, 20, 2012
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4ADT
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![BU of 4adt by Molmil](/molmil-images/mine/4adt) | Crystal structure of plasmodial PLP synthase | Descriptor: | PHOSPHATE ION, PYRIDOXINE BIOSYNTHETIC ENZYME PDX1 HOMOLOGUE, PUTATIVE | Authors: | Guedez, G, Sinning, I, Tews, I. | Deposit date: | 2012-01-03 | Release date: | 2012-01-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Assembly of the Eukaryotic Plp-Synthase Complex from Plasmodium and Activation of the Pdx1 Enzyme. Structure, 20, 2012
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