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3K0X
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CRYSTAL STRUCTURE OF TELOMERE CAPPING PROTEIN TEN1 FROM SACCHAROMYCES POMBE
Descriptor:Protein Ten1, IODIDE ION
Authors:Gelinas, A.D., Reyes, F.E., Batey, R.T., Wuttke, D.S.
Deposit date:2009-09-25
Release date:2009-10-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Telomere capping proteins are structurally related to RPA with an additional telomere-specific domain.
Proc.Natl.Acad.Sci.USA, 106, 2009
3K10
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CRYSTAL STRUCTURE OF TELOMERE CAPPING PROTEIN STN1 FROM SACCHAROMYCES CEREVISIAE
Descriptor:Protein STN1
Authors:Gelinas, A.D., Reyes, F.E., Batey, R.T., Wuttke, D.S.
Deposit date:2009-09-25
Release date:2009-10-27
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Telomere capping proteins are structurally related to RPA with an additional telomere-specific domain.
Proc.Natl.Acad.Sci.USA, 106, 2009
1IKO
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CRYSTAL STRUCTURE OF THE MURINE EPHRIN-B2 ECTODOMAIN
Descriptor:EPHRIN-B2, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE
Authors:Toth, J., Cutforth, T., Gelinas, A.D., Bethoney, K.A., Bard, J., Harrison, C.J.
Deposit date:2001-05-03
Release date:2002-05-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Crystal structure of an ephrin ectodomain.
Dev.Cell, 1, 2001
4HQU
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CRYSTAL STRUCTURE OF HUMAN PDGF-BB IN COMPLEX WITH A MODIFIED NUCLEOTIDE APTAMER (SOMAMER SL5)
Descriptor:Platelet-derived growth factor subunit B, SOMAmer SL5, SODIUM ION, ...
Authors:Davies, D.R., Edwards, T.E., Janjic, N., Gelinas, A.D., Zhang, C., Jarvis, T.C.
Deposit date:2012-10-26
Release date:2012-11-21
Last modified:2012-12-19
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Unique motifs and hydrophobic interactions shape the binding of modified DNA ligands to protein targets.
Proc.Natl.Acad.Sci.USA, 109, 2012
4HQX
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CRYSTAL STRUCTURE OF HUMAN PDGF-BB IN COMPLEX WITH A MODIFIED NUCLEOTIDE APTAMER (SOMAMER SL4)
Descriptor:Platelet-derived growth factor subunit B, SOMAmer SL4, SODIUM ION, ...
Authors:Davies, D.R., Edwards, T.E., Janjic, N., Gelinas, A.D., Zhang, C., Jarvis, T.C.
Deposit date:2012-10-26
Release date:2012-11-21
Last modified:2012-12-19
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Unique motifs and hydrophobic interactions shape the binding of modified DNA ligands to protein targets.
Proc.Natl.Acad.Sci.USA, 109, 2012
4NI7
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CRYSTAL STRUCTURE OF HUMAN INTERLEUKIN 6 IN COMPLEX WITH A MODIFIED NUCLEOTIDE APTAMER (SOMAMER SL1025)
Descriptor:Interleukin-6, SOMAmer SL1025, SODIUM ION
Authors:Davies, D., Edwards, T., Gelinas, A., Jarvis, T., Clifton, M.C.
Deposit date:2013-11-05
Release date:2014-01-22
Last modified:2016-06-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of interleukin-6 in complex with a modified nucleic Acid ligand.
J.Biol.Chem., 289, 2014
4NI9
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CRYSTAL STRUCTURE OF HUMAN INTERLEUKIN 6 IN COMPLEX WITH A MODIFIED NUCLEOTIDE APTAMER (SOMAMER SL1025), FORM 2
Descriptor:SOMAmer SL1025, Interleukin-6, SODIUM ION
Authors:Davies, D., Edwards, T., Gelinas, A., Jarvis, T., Clifton, M.C.
Deposit date:2013-11-05
Release date:2014-01-22
Last modified:2016-06-01
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal structure of interleukin-6 in complex with a modified nucleic Acid ligand.
J.Biol.Chem., 289, 2014
4ZBN
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NON-HELICAL DNA TRIPLEX FORMS A UNIQUE APTAMER SCAFFOLD FOR HIGH AFFINITY RECOGNITION OF NERVE GROWTH FACTOR
Descriptor:DNA (28-MER), Beta-nerve growth factor, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
Authors:Davies, D.R., Edwards, T.E.
Deposit date:2015-04-15
Release date:2015-06-10
Last modified:2015-07-15
Method:X-RAY DIFFRACTION (2.447 Å)
Cite:Non-helical DNA Triplex Forms a Unique Aptamer Scaffold for High Affinity Recognition of Nerve Growth Factor.
Structure, 23, 2015
5UC6
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STRUCTURAL INSIGHTS INTO IL-1 ALPHA RECOGNITION BY A NAPHTHYL-MODIFIED APTAMER THAT MIMICS IL-1RI DOMAIN III
Descriptor:Interleukin-1 alpha, DNA (5'-D(*CP*G)-R(P*(85Y))-D(P*GP*AP*G)-R(P*(85Y)P*(85Y))-D(P*A)-R(P*(85Y))-D(P*GP*GP*G)-R(P*(85Y)P*(85Y))-D(P*AP*GP*AP*G)-R(P*(85Y))-D(P*CP*GP*(ATD))-3'), MAGNESIUM ION, ...
Authors:Ren, X., Pyle, A.
Deposit date:2016-12-21
Release date:2017-10-11
Last modified:2018-08-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for IL-1 alpha recognition by a modified DNA aptamer that specifically inhibits IL-1 alpha signaling.
Nat Commun, 8, 2017