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1L8G
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CRYSTAL STRUCTURE OF PTP1B COMPLEXED WITH 7-(1,1-DIOXO-1H-BENZO[D]ISOTHIAZOL-3-YLOXYMETHYL)-2-(OXALYL-AMINO)-4,7-DIHYDRO-5H-THIENO[2,3-C]PYRAN-3-CARBOXYLIC ACID
Descriptor:PROTEIN-TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1, 7-(1,1-DIOXO-1H-BENZO[D]ISOTHIAZOL-3-YLOXYMETHYL)-2-(OXALYL-AMINO)-4,7-DIHYDRO-5H-THIENO[2,3-C]PYRAN-3-CARBOXYLIC ACID
Authors:Iversen, L.F., Andersen, H.S., Moller, K.B., Olsen, O.H., Peters, G.H., Branner, S., Mortensen, S.B., Hansen, T.K., Lau, J., Ge, Y., Holsworth, D.D., Newman, M.J., Moller, N.P.H.
Deposit date:2002-03-20
Release date:2002-05-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Steric hindrance as a basis for structure-based design of selective inhibitors of protein-tyrosine phosphatases.
Biochemistry, 40, 2001
1NXR
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HIV-1 POLYPURINE HYBRID, R(GAGGACUG):D(CAGTCCTC), NMR, 18 STRUCTURES
Descriptor:DNA (5'-D(*CP*AP*GP*TP*CP*CP*TP*C)-3'), RNA (5'-R(*GP*AP*GP*GP*AP*CP*UP*G)-3')
Authors:Fedoroff, O.Y., Ge, Y., Reid, B.R.
Deposit date:1997-02-21
Release date:1997-07-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of r(gaggacug):d(CAGTCCTC) hybrid: implications for the initiation of HIV-1 (+)-strand synthesis.
J.Mol.Biol., 269, 1997
5M8H
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ATP PHOSPHORIBOSYLTRANSFERASE (HISZG ATPPRT) FROM PSYCHROBACTER ARCTICUS
Descriptor:ATP phosphoribosyltransferase regulatory subunit, ATP phosphoribosyltransferase, STRONTIUM ION, ...
Authors:Alphey, M.S., Ge, Y., Naismith, J.H., da Silva, R.G.
Deposit date:2016-10-28
Release date:2017-09-06
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Kinetics and Structure of a Cold-Adapted Hetero-Octameric ATP Phosphoribosyltransferase.
Biochemistry, 56, 2017
5TUB
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CRYSTAL STRUCTURE OF THE SHARK TBC1D15 GAP DOMAIN
Descriptor:Shark TBC1D15 GTPase-activating Protein
Authors:Chen, Y.-N., Wang, W., Cheng, D., Ge, Y., Gu, X., Zhou, X.E., Ye, F., Xu, H.E., Lv, Z.
Deposit date:2016-11-05
Release date:2017-02-22
Last modified:2017-04-12
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystal structure of TBC1D15 GTPase-activating protein (GAP) domain and its activity on Rab GTPases.
Protein Sci., 26, 2017
5TUC
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CRYSTAL STRUCTURE OF THE SUS TBC1D15 GAP DOMAIN
Descriptor:Sus TBC1D15 GAP Domain
Authors:Chen, Y.-N., Wang, W., Cheng, D., Ge, Y., Gu, X., Zhou, X.E., Ye, F., Xu, H.E., Lv, Z.
Deposit date:2016-11-05
Release date:2017-02-22
Last modified:2017-04-12
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of TBC1D15 GTPase-activating protein (GAP) domain and its activity on Rab GTPases.
Protein Sci., 26, 2017
6FCA
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CATALYTIC SUBUNIT HISG FROM PSYCHROBACTER ARCTICUS ATP PHOSPHORIBOSYLTRANSFERASE (HISZG ATPPRT) IN COMPLEX WITH PRPP
Descriptor:ATP phosphoribosyltransferase, ALPHA-PHOSPHORIBOSYLPYROPHOSPHORIC ACID
Authors:Alphey, M.S., Ge, Y., Fisher, G., Czekster, C.M., Naismith, J.H., da Silva, R.G.
Deposit date:2017-12-20
Release date:2018-10-24
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Catalytic and Anticatalytic Snapshots of a Short-Form ATP Phosphoribosyltransferase
Acs Catalysis, 2018
6FCC
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CATALYTIC SUBUNIT HISG FROM PSYCHROBACTER ARCTICUS ATP PHOSPHORIBOSYLTRANSFERASE (HISZG ATPPRT)
Descriptor:ATP phosphoribosyltransferase, L(+)-TARTARIC ACID
Authors:Alphey, M.S., Ge, Y., Fisher, G., Czekster, C.M., Naismith, J.H., da Silva, R.G.
Deposit date:2017-12-20
Release date:2018-10-24
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Catalytic and Anticatalytic Snapshots of a Short-Form ATP Phosphoribosyltransferase
Acs Catalysis, 2018
6FCT
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CATALYTIC SUBUNIT HISG FROM PSYCHROBACTER ARCTICUS ATP PHOSPHORIBOSYLTRANSFERASE (HISZG ATPPRT) IN COMPLEX WITH PRPP AND ATP
Descriptor:ATP phosphoribosyltransferase, ALPHA-PHOSPHORIBOSYLPYROPHOSPHORIC ACID, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Alphey, M.S., Ge, Y., Fisher, G., Czekster, C.M., Naismith, J.H., da Silva, R.G.
Deposit date:2017-12-21
Release date:2018-10-24
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Catalytic and Anticatalytic Snapshots of a Short-Form ATP Phosphoribosyltransferase
Acs Catalysis, 2018
6FCW
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CATALYTIC SUBUNIT HISG FROM PSYCHROBACTER ARCTICUS ATP PHOSPHORIBOSYLTRANSFERASE (HISZG ATPPRT) IN COMPLEX WITH PRATP
Descriptor:ATP phosphoribosyltransferase, PHOSPHORIBOSYL ATP, MAGNESIUM ION
Authors:Alphey, M.S., Ge, Y., Fisher, G., Czekster, C.M., Naismith, J.H., da Silva, R.G.
Deposit date:2017-12-21
Release date:2018-10-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Catalytic and Anticatalytic Snapshots of a Short-Form ATP Phosphoribosyltransferase
Acs Catalysis, 2018
6FCY
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CATALYTIC SUBUNIT HISG FROM PSYCHROBACTER ARCTICUS ATP PHOSPHORIBOSYLTRANSFERASE (HISZG ATPPRT) IN COMPLEX WITH PRPP AND ADP
Descriptor:ATP phosphoribosyltransferase, ALPHA-PHOSPHORIBOSYLPYROPHOSPHORIC ACID, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Alphey, M.S., Ge, Y., Fisher, G., Czekster, C.M., Naismith, J.H., da Silva, R.G.
Deposit date:2017-12-21
Release date:2018-10-24
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Catalytic and Anticatalytic Snapshots of a Short-Form ATP Phosphoribosyltransferase
Acs Catalysis, 2018
6FD9
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CATALYTIC SUBUNIT HISG FROM PSYCHROBACTER ARCTICUS ATP PHOSPHORIBOSYLTRANSFERASE (HISZG ATPPRT) IN COMPLEX WITH AMP
Descriptor:ATP phosphoribosyltransferase, ADENOSINE MONOPHOSPHATE
Authors:Alphey, M.S., Ge, Y., Fisher, G., Czekster, C.M., Naismith, J.H., da Silva, R.G.
Deposit date:2017-12-22
Release date:2018-10-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Catalytic and Anticatalytic Snapshots of a Short-Form ATP Phosphoribosyltransferase
Acs Catalysis, 2018
6FTT
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ATP PHOSPHORIBOSYLTRANSFERASE (HISZG ATPPRT) FROM PSYCHROBACTER ARCTICUS IN COMPLEX WITH PRPP
Descriptor:ATP phosphoribosyltransferase regulatory subunit, ATP phosphoribosyltransferase, MAGNESIUM ION, ...
Authors:Alphey, M.S., Ge, Y., Fisher, G., Czekster, C.M., Naismith, J.H., da Silva, R.G.
Deposit date:2018-02-23
Release date:2018-10-24
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Catalytic and Anticatalytic Snapshots of a Short-Form ATP Phosphoribosyltransferase
Acs Catalysis, 2018
6FU2
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ATP PHOSPHORIBOSYLTRANSFERASE (HISZG ATPPRT) FROM PSYCHROBACTER ARCTICUS IN COMPLEX WITH PRPP AND ATP
Descriptor:ATP phosphoribosyltransferase regulatory subunit, ATP phosphoribosyltransferase, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Alphey, M.S., Ge, Y., Fisher, G., Czekster, C.M., Naismith, J.H., da Silva, R.G.
Deposit date:2018-02-26
Release date:2018-10-24
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Catalytic and Anticatalytic Snapshots of a Short-Form ATP Phosphoribosyltransferase
Acs Catalysis, 2018
6FU7
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ATP PHOSPHORIBOSYLTRANSFERASE (HISZG ATPPRT) FROM PSYCHROBACTER ARCTICUS IN COMPLEX WITH PRATP
Descriptor:ATP phosphoribosyltransferase regulatory subunit, ATP phosphoribosyltransferase, CHLORIDE ION, ...
Authors:Alphey, M.S., Ge, Y., Fisher, G., Czekster, C.M., Naismith, J.H., da Silva, R.G.
Deposit date:2018-02-26
Release date:2018-10-24
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Catalytic and Anticatalytic Snapshots of a Short-Form ATP Phosphoribosyltransferase
Acs Catalysis, 2018
6FUA
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ATP PHOSPHORIBOSYLTRANSFERASE (HISZG ATPPRT) FROM PSYCHROBACTER ARCTICUS IN COMPLEX WITH PRPP AND ADP
Descriptor:ATP phosphoribosyltransferase regulatory subunit, ATP phosphoribosyltransferase, CHLORIDE ION, ...
Authors:Alphey, M.S., Ge, Y., Fisher, G., Czekster, C.M., Naismith, J.H., da Silva, R.G.
Deposit date:2018-02-26
Release date:2018-10-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Catalytic and Anticatalytic Snapshots of a Short-Form ATP Phosphoribosyltransferase
Acs Catalysis, 2018
5VIE
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ELECTROPHILIC PROBES FOR DECIPHERING SUBSTRATE RECOGNITION BY O-GLCNAC TRANSFERASE
Descriptor:UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, CKII, URIDINE-5'-DIPHOSPHATE, ...
Authors:Jiang, J., Li, B., Hu, C.-W., Worth, M., Fan, D., Li, H.
Deposit date:2017-04-15
Release date:2017-10-18
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase.
Nat. Chem. Biol., 13, 2017
5VIF
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ELECTROPHILIC PROBES FOR DECIPHERING SUBSTRATE RECOGNITION BY O-GLCNAC TRANSFERASE
Descriptor:UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, CKII, URIDINE-5'-DIPHOSPHATE, ...
Authors:Jiang, J., Li, B., Hu, C.-W., Worth, M., Fan, D., Li, H.
Deposit date:2017-04-15
Release date:2017-10-18
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase.
Nat. Chem. Biol., 13, 2017