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7RB2
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BU of 7rb2 by Molmil
Cryo-EM structure of SARS-CoV-2 NSP15 NendoU in BIS-Tris pH 6.0
Descriptor: Uridylate-specific endoribonuclease
Authors:Godoy, A.S, Song, Y, Nakamura, A.M, Noske, G.D, Gawriljuk, V.O, Fernandes, R.S, Oliva, G.
Deposit date:2021-07-05
Release date:2021-07-14
Last modified:2023-06-21
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:Allosteric regulation and crystallographic fragment screening of SARS-CoV-2 NSP15 endoribonuclease.
Nucleic Acids Res., 51, 2023
7RB0
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BU of 7rb0 by Molmil
Cryo-EM structure of SARS-CoV-2 NSP15 NendoU at pH 7.5
Descriptor: Uridylate-specific endoribonuclease
Authors:Godoy, A.S, Song, Y, Nakamura, A.M, Noske, G.D, Gawriljuk, V.O, Fernandes, R.S, Oliva, G.
Deposit date:2021-07-05
Release date:2021-07-14
Last modified:2023-06-21
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Allosteric regulation and crystallographic fragment screening of SARS-CoV-2 NSP15 endoribonuclease.
Nucleic Acids Res., 51, 2023
7KPH
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BU of 7kph by Molmil
SARS-CoV-2 Main Protease in mature form
Descriptor: 3C-like proteinase
Authors:Noske, G.D, Nakamura, A.M, Gawriljuk, V.O, Lima, G.M.A, Zeri, A.C.M, Nascimento, A.F.Z, Oliva, G, Godoy, A.S.
Deposit date:2020-11-11
Release date:2020-11-18
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:A Crystallographic Snapshot of SARS-CoV-2 Main Protease Maturation Process.
J.Mol.Biol., 433, 2021
7KVR
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BU of 7kvr by Molmil
SARS-CoV-2 Main protease immature form - FMAX Library E09 fragment
Descriptor: 3C-like proteinase, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ...
Authors:Noske, G.D, Nakamura, A.M, Gawriljuk, V.O, Lima, G.M.A, Zeri, A.C.M, Nascimento, A.F.Z, Fernandes, R.S, Oliva, G, Godoy, A.S.
Deposit date:2020-11-28
Release date:2020-12-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:A Crystallographic Snapshot of SARS-CoV-2 Main Protease Maturation Process.
J.Mol.Biol., 433, 2021
7LDX
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BU of 7ldx by Molmil
SARS-CoV-2 Main protease immature form - F2X Entry Library E06 fragment
Descriptor: (3-endo)-8-benzyl-8-azabicyclo[3.2.1]octan-3-ol, 3C-like proteinase, DI(HYDROXYETHYL)ETHER, ...
Authors:Noske, G.D, Nakamura, A.M, Gawriljuk, V.O, Lima, G.M.A, Zeri, A.C.M, Nascimento, A.F.Z, Oliva, G, Godoy, A.S.
Deposit date:2021-01-14
Release date:2021-01-20
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:A Crystallographic Snapshot of SARS-CoV-2 Main Protease Maturation Process.
J.Mol.Biol., 433, 2021
7LFE
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BU of 7lfe by Molmil
SARS-CoV-2 Main protease immature form - F2X Entry Library E03 fragment
Descriptor: (2R,4R)-1-phenylhexahydropyrimidine-2,4-diol, 3C-like proteinase, DI(HYDROXYETHYL)ETHER, ...
Authors:Noske, G.D, Nakamura, A.M, Gawriljuk, V.O, Lima, G.M.A, Zeri, A.C.M, Nascimento, A.F.Z, Oliva, G, Godoy, A.S.
Deposit date:2021-01-16
Release date:2021-02-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:A Crystallographic Snapshot of SARS-CoV-2 Main Protease Maturation Process.
J.Mol.Biol., 433, 2021
7LFP
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BU of 7lfp by Molmil
SARS-CoV-2 Main protease immature form - F2X Entry Library G05 fragment
Descriptor: 3C-like proteinase, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ...
Authors:Noske, G.D, Nakamura, A.M, Gawriljuk, V.O, Lima, G.M.A, Zeri, A.C.M, Nascimento, A.F.Z, Oliva, G, Godoy, A.S.
Deposit date:2021-01-18
Release date:2021-02-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A Crystallographic Snapshot of SARS-CoV-2 Main Protease Maturation Process.
J.Mol.Biol., 433, 2021
7KVL
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BU of 7kvl by Molmil
SARS-CoV-2 Main protease immature form - FMAX Library E01 fragment
Descriptor: 2-chloropyridine-4-carboxamide, 3C-like proteinase, DI(HYDROXYETHYL)ETHER, ...
Authors:Noske, G.D, Nakamura, A.M, Gawriljuk, V.O, Lima, G.M.A, Zeri, A.C.M, Nascimento, A.F.Z, Fernandes, R.S, Oliva, G, Godoy, A.S.
Deposit date:2020-11-28
Release date:2020-12-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:A Crystallographic Snapshot of SARS-CoV-2 Main Protease Maturation Process.
J.Mol.Biol., 433, 2021
7MBG
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BU of 7mbg by Molmil
SARS-CoV-2 Main protease in orthorhombic space group
Descriptor: 3C-like proteinase, DIMETHYL SULFOXIDE
Authors:Fearon, D, Douangamath, A, von Delft, F, Noske, G.D, Nakamura, A.M, Gawriljuk, V.O, Lima, G.M.A, Zeri, A.C.M, Nascimento, A.F.Z, Oliva, G, Godoy, A.S.
Deposit date:2021-03-31
Release date:2021-04-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:A Crystallographic Snapshot of SARS-CoV-2 Main Protease Maturation Process.
J.Mol.Biol., 433, 2021
7ME0
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BU of 7me0 by Molmil
Cryo-EM structure of SARS-CoV-2 NSP15 NendoU at pH 6.0
Descriptor: Uridylate-specific endoribonuclease
Authors:Godoy, A.S, Song, Y, Nakamura, A.M, Noske, G.D, Gawriljuk, V.O, Fernandes, R.S, Oliva, G.
Deposit date:2021-04-06
Release date:2021-04-14
Last modified:2023-05-10
Method:ELECTRON MICROSCOPY (2.48 Å)
Cite:Allosteric regulation and crystallographic fragment screening of SARS-CoV-2 NSP15 endoribonuclease.
Nucleic Acids Res., 2023
7N5Z
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BU of 7n5z by Molmil
SARS-CoV-2 Main protease C145S mutant
Descriptor: 3C-like proteinase
Authors:Noske, G.D, Nakamura, A.M, Gawriljuk, V.O, Lima, G.M.A, Zeri, A.C.M, Nascimento, A.F.Z, Oliva, G, Godoy, A.S.
Deposit date:2021-06-07
Release date:2021-06-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:A Crystallographic Snapshot of SARS-CoV-2 Main Protease Maturation Process.
J.Mol.Biol., 433, 2021
7N6N
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BU of 7n6n by Molmil
SARS-CoV-2 Main protease C145S mutant in complex with N and C-terminal residues
Descriptor: 3C-like proteinase
Authors:Noske, G.D, Nakamura, A.M, Gawriljuk, V.O, Lima, G.M.A, Zeri, A.C.M, Nascimento, A.F.Z, Fernandes, R.S, Oliva, G, Godoy, A.S.
Deposit date:2021-06-08
Release date:2021-06-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A Crystallographic Snapshot of SARS-CoV-2 Main Protease Maturation Process.
J.Mol.Biol., 433, 2021
7KEH
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BU of 7keh by Molmil
Crystal structure from SARS-CoV-2 NendoU NSP15
Descriptor: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION, Uridylate-specific endoribonuclease
Authors:Godoy, A.S, Nakamura, A.M, Pereira, H.M, Noske, G.D, Gawriljuk, V.O, Fernandes, R.S, Oliveira, K.I.Z, Oliva, G.
Deposit date:2020-10-10
Release date:2020-12-02
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Allosteric regulation and crystallographic fragment screening of SARS-CoV-2 NSP15 endoribonuclease.
Nucleic Acids Res., 2023
7KEG
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BU of 7keg by Molmil
Crystal structure from SARS-COV2 NendoU NSP15
Descriptor: PHOSPHATE ION, Uridylate-specific endoribonuclease
Authors:Godoy, A.S, Nakamura, A.M, Pereira, H.M, Noske, G.D, Gawriljuk, V.O, Fernandes, R.S, Oliveira, K.I.Z, Oliva, G.
Deposit date:2020-10-10
Release date:2020-12-02
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Allosteric regulation and crystallographic fragment screening of SARS-CoV-2 NSP15 endoribonuclease.
Nucleic Acids Res., 2023
7KFI
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BU of 7kfi by Molmil
SARS-CoV-2 Main protease immature form - apo structure
Descriptor: 3C-like proteinase, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE
Authors:Noske, G.D, Nakamura, A.M, Gawriljuk, V.O, Lima, G.M.A, Zeri, A.C.M, Nascimento, A.F.Z, Oliva, G, Godoy, A.S.
Deposit date:2020-10-14
Release date:2020-10-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A Crystallographic Snapshot of SARS-CoV-2 Main Protease Maturation Process.
J.Mol.Biol., 433, 2021
7KF4
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BU of 7kf4 by Molmil
Crystal structure from SARS-CoV-2 NendoU NSP15
Descriptor: CITRIC ACID, Uridylate-specific endoribonuclease
Authors:Godoy, A.S, Nakamura, A.M, Pereira, H.M, Noske, G.D, Gawriljuk, V.O, Fernandes, R.S, Oliveira, K.I.Z, Oliva, G.
Deposit date:2020-10-13
Release date:2020-12-02
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Allosteric regulation and crystallographic fragment screening of SARS-CoV-2 NSP15 endoribonuclease.
Nucleic Acids Res., 2023
8OGH
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BU of 8ogh by Molmil
Truncated 1-deoxy-D-xylulose 5-phosphate synthase (DXPS) from Mycobacterium tuberculosis with butylacetylphosphonate (BAP) bound
Descriptor: 1,2-ETHANEDIOL, 1-deoxy-D-xylulose-5-phosphate synthase, DI(HYDROXYETHYL)ETHER, ...
Authors:Gawriljuk, O.V, Oerlemans, R, Groves, R.M.
Deposit date:2023-03-20
Release date:2023-05-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of Mycobacterium tuberculosis 1-Deoxy-D-Xylulose 5-Phosphate Synthase in Complex with Butylacetylphosphonate
Crystals, 13, 2023
6URV
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BU of 6urv by Molmil
Crystal structure of Yellow Fever Virus NS2B-NS3 protease domain
Descriptor: NS2B, NS3 protease
Authors:Noske, G.D, Gawriljuk, V.F.O, Fernandes, R.S, Oliva, G, Godoy, A.S.
Deposit date:2019-10-24
Release date:2020-01-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural characterization and polymorphism analysis of the NS2B-NS3 protease from the 2017 Brazilian circulating strain of Yellow Fever virus.
Biochim Biophys Acta Gen Subj, 1864, 2020
7A9G
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BU of 7a9g by Molmil
Truncated 1-deoxy-D-xylulose 5-phosphate synthase (DXS) from Mycobacterium tuberculosis with intermediate 2-acetyl-thiamine diphosphate
Descriptor: 1-deoxy-D-xylulose-5-phosphate synthase,1-deoxy-D-xylulose-5-phosphate synthase, 2-ACETYL-THIAMINE DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ...
Authors:Gierse, R.M, Reddem, E, Grooves, M.R.
Deposit date:2020-09-02
Release date:2022-03-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:First crystal structures of 1-deoxy-D-xylulose 5-phosphate synthase (DXPS) from Mycobacterium tuberculosis indicate a distinct mechanism of intermediate stabilization.
Sci Rep, 12, 2022
7A9H
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BU of 7a9h by Molmil
Truncated 1-deoxy-D-xylulose 5-phosphate synthase (DXS) from Mycobacterium tuberculosis
Descriptor: 1-deoxy-D-xylulose-5-phosphate synthase,1-deoxy-D-xylulose-5-phosphate synthase, MAGNESIUM ION, THIAMINE DIPHOSPHATE
Authors:Gierse, R.M, Reddem, E, Grooves, M.R.
Deposit date:2020-09-02
Release date:2022-03-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.849 Å)
Cite:First crystal structures of 1-deoxy-D-xylulose 5-phosphate synthase (DXPS) from Mycobacterium tuberculosis indicate a distinct mechanism of intermediate stabilization.
Sci Rep, 12, 2022
7N7Y
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BU of 7n7y by Molmil
Crystal Structure of SARS-CoV-2 NendoU in complex with Z18197050
Descriptor: Uridylate-specific endoribonuclease, methyl 4-sulfamoylbenzoate
Authors:Godoy, A.S, Douangamath, A, Nakamura, A.M, Dias, A, Krojer, T, Noske, G.D, Gawiljuk, V.O, Fernandes, R.S, Fairhead, M, Powell, A, Dunnet, L, Aimon, A, Fearon, D, Brandao-Neto, J, Skyner, R, von Delft, F, Oliva, G.
Deposit date:2021-06-11
Release date:2021-09-08
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Allosteric regulation and crystallographic fragment screening of SARS-CoV-2 NSP15 endoribonuclease.
Nucleic Acids Res., 51, 2023
7N7U
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BU of 7n7u by Molmil
Crystal Structure of SARS-CoV-2 NendoU in complex with LIZA-7
Descriptor: 1-[(2~{R},4~{S},5~{R})-5-[[(azanylidene-$l^{4}-azanylidene)amino]methyl]-4-oxidanyl-oxolan-2-yl]-5-methyl-pyrimidine-2,4-dione, Uridylate-specific endoribonuclease
Authors:Godoy, A.S, Douangamath, A, Nakamura, A.M, Dias, A, Krojer, T, Noske, G.D, Gawiljuk, V.O, Fernandes, R.S, Fairhead, M, Powell, A, Dunnet, L, Aimon, A, Fearon, D, Brandao-Neto, J, Skyner, R, von Delft, F, Oliva, G.
Deposit date:2021-06-11
Release date:2021-09-08
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Allosteric regulation and crystallographic fragment screening of SARS-CoV-2 NSP15 endoribonuclease.
Nucleic Acids Res., 51, 2023
7N83
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BU of 7n83 by Molmil
Crystal Structure of SARS-CoV-2 NendoU in complex with Z2443429438
Descriptor: (3S)-1-(phenylsulfonyl)pyrrolidin-3-amine, CITRIC ACID, Uridylate-specific endoribonuclease
Authors:Godoy, A.S, Douangamath, A, Nakamura, A.M, Dias, A, Krojer, T, Noske, G.D, Gawiljuk, V.O, Fernandes, R.S, Fairhead, M, Powell, A, Dunnet, L, Aimon, A, Fearon, D, Brandao-Neto, J, Skyner, R, von Delft, F, Oliva, G.
Deposit date:2021-06-12
Release date:2021-09-08
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Allosteric regulation and crystallographic fragment screening of SARS-CoV-2 NSP15 endoribonuclease.
Nucleic Acids Res., 51, 2023
7N7W
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BU of 7n7w by Molmil
Crystal Structure of SARS-CoV-2 NendoU in complex with CSC000178569
Descriptor: N-(2-fluorophenyl)-N'-methylurea, Uridylate-specific endoribonuclease
Authors:Godoy, A.S, Douangamath, A, Nakamura, A.M, Dias, A, Krojer, T, Noske, G.D, Gawiljuk, V.O, Fernandes, R.S, Fairhead, M, Powell, A, Dunnet, L, Aimon, A, Fearon, D, Brandao-Neto, J, Skyner, R, von Delft, F, Oliva, G.
Deposit date:2021-06-11
Release date:2021-09-08
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Allosteric regulation and crystallographic fragment screening of SARS-CoV-2 NSP15 endoribonuclease.
Nucleic Acids Res., 51, 2023
7N7R
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BU of 7n7r by Molmil
Crystal Structure of SARS-CoV-2 NendoU in complex with Z2472938267
Descriptor: 1-[2-(2-oxidanylidenepyrrolidin-1-yl)ethyl]-3-phenyl-urea, Uridylate-specific endoribonuclease
Authors:Godoy, A.S, Douangamath, A, Nakamura, A.M, Dias, A, Krojer, T, Noske, G.D, Gawiljuk, V.O, Fernandes, R.S, Fairhead, M, Powell, A, Dunnet, L, Aimon, A, Fearon, D, Brandao-Neto, J, Skyner, R, von Delft, F, Oliva, G.
Deposit date:2021-06-11
Release date:2021-09-08
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Allosteric regulation and crystallographic fragment screening of SARS-CoV-2 NSP15 endoribonuclease.
Nucleic Acids Res., 51, 2023

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PDB entries from 2024-03-27

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