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6SYT
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BU of 6syt by Molmil
Structure of the SMG1-SMG8-SMG9 complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ...
Authors:Gat, Y, Schuller, J.M, Conti, E.
Deposit date:2019-10-01
Release date:2019-12-11
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (3.45 Å)
Cite:InsP6binding to PIKK kinases revealed by the cryo-EM structure of an SMG1-SMG8-SMG9 complex.
Nat.Struct.Mol.Biol., 26, 2019
4P2L
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BU of 4p2l by Molmil
Quiescin Sulfhydryl Oxidase from Rattus norvegicus
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Sulfhydryl oxidase 1
Authors:Gat, Y, Fass, D.
Deposit date:2014-03-04
Release date:2014-06-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Enzyme structure captures four cysteines aligned for disulfide relay.
Protein Sci., 23, 2014
6Z3R
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BU of 6z3r by Molmil
Structure of SMG1-8-9 kinase complex bound to UPF1-LSQ
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ...
Authors:Langer, L.M, Gat, Y, Conti, E.
Deposit date:2020-05-21
Release date:2020-06-24
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:Structure of substrate-bound SMG1-8-9 kinase complex reveals molecular basis for phosphorylation specificity.
Elife, 9, 2020
4YEQ
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BU of 4yeq by Molmil
L4b Domain of Human Laminin alpha-2
Descriptor: Laminin subunit alpha-2
Authors:Toot, M, Gat, Y, Fass, D.
Deposit date:2015-02-24
Release date:2015-05-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Laminin L4 domain structure resembles adhesion modules in ephrin receptor and other transmembrane glycoproteins.
Febs J., 282, 2015
4YEP
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BU of 4yep by Molmil
L4b Domain of Human Laminin alpha-2
Descriptor: 1,2-ETHANEDIOL, Laminin subunit alpha-2
Authors:Toot, M, Gat, Y, Fass, D.
Deposit date:2015-02-24
Release date:2015-05-27
Last modified:2015-07-22
Method:X-RAY DIFFRACTION (1.19 Å)
Cite:Laminin L4 domain structure resembles adhesion modules in ephrin receptor and other transmembrane glycoproteins.
Febs J., 282, 2015
3T58
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BU of 3t58 by Molmil
C76A/C455S mutant of mouse QSOX1 containing an interdomain disulfide
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Sulfhydryl oxidase 1
Authors:Fass, D, Alon, A, Gat, Y.
Deposit date:2011-07-27
Release date:2012-05-30
Last modified:2012-08-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The dynamic disulphide relay of quiescin sulphydryl oxidase.
Nature, 488, 2012
3T59
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BU of 3t59 by Molmil
C76A/C455S mutant of mouse QSOX1 containing an interdomain disulfide
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Sulfhydryl oxidase 1
Authors:Fass, D, Alon, A, Gat, Y.
Deposit date:2011-07-27
Release date:2012-05-30
Last modified:2012-08-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The dynamic disulphide relay of quiescin sulphydryl oxidase.
Nature, 488, 2012
3Q6O
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BU of 3q6o by Molmil
Oxidoreductase Fragment of Human QSOX1
Descriptor: SULFATE ION, Sulfhydryl oxidase 1
Authors:Fass, D, Alon, A.
Deposit date:2011-01-03
Release date:2012-05-30
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The dynamic disulphide relay of quiescin sulphydryl oxidase.
Nature, 488, 2012
3QD9
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BU of 3qd9 by Molmil
C72S/C353S mutant of Trypanosoma brucei QSOX containing an interdomain disulfide
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, QSOX from Trypanosoma brucei (TbQSOX)
Authors:Alon, A, Fass, D.
Deposit date:2011-01-18
Release date:2012-05-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The dynamic disulphide relay of quiescin sulphydryl oxidase.
Nature, 488, 2012
3QCP
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BU of 3qcp by Molmil
QSOX from Trypanosoma brucei
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, QSOX from Trypanosoma brucei (TbQSOX)
Authors:Alon, A, Fass, D.
Deposit date:2011-01-17
Release date:2012-05-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The dynamic disulphide relay of quiescin sulphydryl oxidase.
Nature, 488, 2012
7PW8
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BU of 7pw8 by Molmil
Human SMG1-8-9 kinase complex bound to AMPPNP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ...
Authors:Langer, L.M, Conti, E.
Deposit date:2021-10-06
Release date:2021-12-01
Method:ELECTRON MICROSCOPY (2.82 Å)
Cite:Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8.
Elife, 10, 2021
7PW5
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BU of 7pw5 by Molmil
Human SMG1-8-9 kinase complex with AlphaFold predicted SMG8 C-terminus, bound to a SMG1 inhibitor
Descriptor: 1-[4-[4-[2-[[4-chloranyl-3-(diethylsulfamoyl)phenyl]amino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methyl-urea, ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ...
Authors:Langer, L.M, Conti, E.
Deposit date:2021-10-06
Release date:2021-12-01
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8.
Elife, 10, 2021
7PW9
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BU of 7pw9 by Molmil
Human SMG1-9 kinase complex bound to AMPPNP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ...
Authors:Langer, L.M, Conti, E.
Deposit date:2021-10-06
Release date:2021-12-01
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8.
Elife, 10, 2021
7PW7
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BU of 7pw7 by Molmil
Human SMG1-9 kinase complex bound to a SMG1 inhibitor
Descriptor: 1-[4-[4-[2-[[4-chloranyl-3-(diethylsulfamoyl)phenyl]amino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methyl-urea, ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ...
Authors:Langer, L.M, Conti, E.
Deposit date:2021-10-06
Release date:2021-12-01
Method:ELECTRON MICROSCOPY (3.59 Å)
Cite:Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8.
Elife, 10, 2021
7PW4
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BU of 7pw4 by Molmil
Human SMG1-8-9 kinase complex bound to a SMG1 inhibitor
Descriptor: 1-[4-[4-[2-[[4-chloranyl-3-(diethylsulfamoyl)phenyl]amino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methyl-urea, ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ...
Authors:Langer, L.M, Conti, E.
Deposit date:2021-10-06
Release date:2021-12-01
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8.
Elife, 10, 2021
7PW6
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BU of 7pw6 by Molmil
Human SMG1-8-9 kinase complex bound to a SMG1 inhibitor - SMG1 body
Descriptor: 1-[4-[4-[2-[[4-chloranyl-3-(diethylsulfamoyl)phenyl]amino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methyl-urea, INOSITOL HEXAKISPHOSPHATE, Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1
Authors:Langer, L.M, Conti, E.
Deposit date:2021-10-06
Release date:2021-12-01
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8.
Elife, 10, 2021
4TVE
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BU of 4tve by Molmil
Structure Of the First Two Thioredoxin Domains of Naumovozyma dairenensis Eps1p
Descriptor: Naumovozyma dairenensis Eps1p
Authors:Deborah, F, Biran, S.
Deposit date:2014-06-26
Release date:2014-12-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The eps1p protein disulfide isomerase conserves classic thioredoxin superfamily amino Acid motifs but not their functional geometries.
Plos One, 9, 2014
4TW5
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BU of 4tw5 by Molmil
Structure Of the First Two Thioredoxin Domains of Saccharomyces cerevisiae Eps1p
Descriptor: Eps1p
Authors:Fass, D, Biran, S.
Deposit date:2014-06-30
Release date:2014-12-17
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:The eps1p protein disulfide isomerase conserves classic thioredoxin superfamily amino Acid motifs but not their functional geometries.
Plos One, 9, 2014
3ASD
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BU of 3asd by Molmil
MamA R50E mutant
Descriptor: MamA
Authors:Zeytuni, N, Davidov, G, Zarivach, R.
Deposit date:2010-12-10
Release date:2011-07-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Self-recognition mechanism of MamA, a magnetosome-associated TPR-containing protein, promotes complex assembly
Proc.Natl.Acad.Sci.USA, 108, 2011
3AS4
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BU of 3as4 by Molmil
MamA AMB-1 C2221
Descriptor: MamA, SULFATE ION
Authors:Zeytuni, N, Davidov, G, Zarivach, R.
Deposit date:2010-12-09
Release date:2011-07-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Self-recognition mechanism of MamA, a magnetosome-associated TPR-containing protein, promotes complex assembly
Proc.Natl.Acad.Sci.USA, 108, 2011
3ASF
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BU of 3asf by Molmil
MamA MSR-1 C2
Descriptor: Magnetosome protein MamA, SULFATE ION
Authors:Zeytuni, N, Davidov, G, Zarivach, R.
Deposit date:2010-12-11
Release date:2011-07-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Self-recognition mechanism of MamA, a magnetosome-associated TPR-containing protein, promotes complex assembly
Proc.Natl.Acad.Sci.USA, 108, 2011
3AS8
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BU of 3as8 by Molmil
MamA MSR-1 P41212
Descriptor: Magnetosome protein MamA, SULFATE ION
Authors:Zeytuni, N, Davidov, G, Zarivach, R.
Deposit date:2010-12-10
Release date:2011-07-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Self-recognition mechanism of MamA, a magnetosome-associated TPR-containing protein, promotes complex assembly
Proc.Natl.Acad.Sci.USA, 108, 2011
3ASH
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BU of 3ash by Molmil
MamA D159K mutant 1
Descriptor: MamA, SULFATE ION
Authors:Zeytuni, N, Levin, M, Davidov, G, Zarivach, R.
Deposit date:2010-12-11
Release date:2011-07-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Self-recognition mechanism of MamA, a magnetosome-associated TPR-containing protein, promotes complex assembly
Proc.Natl.Acad.Sci.USA, 108, 2011
3AS5
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BU of 3as5 by Molmil
MamA AMB-1 P212121
Descriptor: MAGNESIUM ION, MamA
Authors:Zeytuni, N, Davidov, G, Zarivach, R.
Deposit date:2010-12-10
Release date:2011-07-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Self-recognition mechanism of MamA, a magnetosome-associated TPR-containing protein, promotes complex assembly
Proc.Natl.Acad.Sci.USA, 108, 2011
3ASG
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BU of 3asg by Molmil
MamA D159K mutant 2
Descriptor: MamA
Authors:Zeytuni, N, Levin, M, Davidov, G, Zarivach, R.
Deposit date:2010-12-11
Release date:2011-07-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Self-recognition mechanism of MamA, a magnetosome-associated TPR-containing protein, promotes complex assembly
Proc.Natl.Acad.Sci.USA, 108, 2011

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