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1MJL
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BU of 1mjl by Molmil
METHIONINE REPRESSOR MUTANT (Q44K) COMPLEX WITH THE COREPRESSOR SAM (S-ADENOSYL METHIONINE) FROM ESCHERICHIA COLI
Descriptor: METHIONINE REPRESSOR PROTEIN METJ, S-ADENOSYLMETHIONINE
Authors:Garvie, C.W, Phillips, S.E.V.
Deposit date:1998-01-26
Release date:1998-04-29
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystallographic studies of the methionine repressor-operator complex and the oc31 42kDa repressor
Thesis, University of Leeds, 1997
1MJK
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BU of 1mjk by Molmil
METHIONINE REPRESSOR MUTANT APOREPRESSOR (Q44K) FROM ESCHERICHIA COLI
Descriptor: METHIONINE REPRESSOR, PHOSPHATE ION
Authors:Garvie, C.W, Phillips, S.E.V.
Deposit date:1998-01-16
Release date:1998-05-27
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystallographic studies of the methionine repressor-operator complex and the oc31 42kDa repressor
Thesis, University of Leeds, 1997
1K7A
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BU of 1k7a by Molmil
Ets-1(331-440)+GGAG duplex
Descriptor: C-ets-1 Protein, DNA (5'-D(*CP*AP*CP*AP*TP*CP*TP*CP*CP*GP*GP*CP*AP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*TP*GP*CP*CP*GP*GP*AP*GP*AP*TP*GP*T)-3')
Authors:Garvie, C.W, Hagman, J, Wolberger, C.
Deposit date:2001-10-18
Release date:2002-01-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural studies of Ets-1/Pax5 complex formation on DNA.
Mol.Cell, 8, 2001
1K78
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BU of 1k78 by Molmil
Pax5(1-149)+Ets-1(331-440)+DNA
Descriptor: C-ets-1 Protein, Paired Box Protein Pax5, Pax5/Ets Binding Site on the mb-1 promoter
Authors:Garvie, C.W, Hagman, J, Wolberger, C.
Deposit date:2001-10-18
Release date:2002-01-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural studies of Ets-1/Pax5 complex formation on DNA.
Mol.Cell, 8, 2001
1K79
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BU of 1k79 by Molmil
Ets-1(331-440)+GGAA duplex
Descriptor: C-ets-1 protein, DNA (5'-D(*CP*AP*CP*AP*TP*TP*TP*CP*CP*GP*GP*CP*AP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*TP*GP*CP*CP*GP*GP*AP*AP*AP*TP*GP*T)-3')
Authors:Garvie, C.W, Hagman, J, Wolberger, C.
Deposit date:2001-10-18
Release date:2002-01-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural studies of Ets-1/Pax5 complex formation on DNA.
Mol.Cell, 8, 2001
1MJP
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BU of 1mjp by Molmil
METHIONINE APOREPRESSOR MUTANT (Q44K) COMPLEXED TO THE MINIMAL MET CONSENSUS OPERATOR
Descriptor: CONSENSUS OPERATOR DUPLEX, METHIONINE REPRESSOR
Authors:Garvie, C.W, Phillips, S.E.V.
Deposit date:1998-01-29
Release date:1999-08-02
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Direct and indirect readout in mutant Met repressor-operator complexes.
Structure Fold.Des., 8, 2000
1MJQ
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BU of 1mjq by Molmil
METHIONINE REPRESSOR MUTANT (Q44K) PLUS COREPRESSOR (S-ADENOSYL METHIONINE) COMPLEXED TO AN ALTERED MET CONSENSUS OPERATOR SEQUENCE
Descriptor: METHIONINE REPRESSOR, MUTATED MET CONSENSUS OPERATOR DUPLEX, S-ADENOSYLMETHIONINE
Authors:Garvie, C.W, Phillips, S.E.V.
Deposit date:1998-01-30
Release date:1999-08-02
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Direct and indirect readout in mutant Met repressor-operator complexes.
Structure Fold.Des., 8, 2000
1MDM
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BU of 1mdm by Molmil
INHIBITED FRAGMENT OF ETS-1 AND PAIRED DOMAIN OF PAX5 BOUND TO DNA
Descriptor: C-ETS-1 PROTEIN, PAIRED BOX PROTEIN PAX-5, PAX5/ETS BINDING SITE ON THE MB-1 PROMOTER
Authors:Garvie, C.W, Pufall, M.A, Graves, B.J, Wolberger, C.
Deposit date:2002-08-07
Release date:2002-12-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:STRUCTURAL ANALYSIS OF THE AUTOINHIBITION OF ETS-1 AND ITS ROLE IN PROTEIN PARTNERSHIPS
J.Biol.Chem., 277, 2002
1MD0
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BU of 1md0 by Molmil
CRYSTAL STRUCTURE OF AN INHIBITED FRAGMENT OF Ets-1
Descriptor: C-ets-1 protein
Authors:Garvie, C.W, Pufall, M.A, Graves, B.J, Wolberger, C.
Deposit date:2002-08-06
Release date:2002-12-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Analysis of the Autoinhibition of Ets-1 and Its Role in Protein Partnerships
J.Biol.Chem., 277, 2002
1MJM
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BU of 1mjm by Molmil
METHIONINE APOREPRESSOR MUTANT (Q44K) COMPLEXED TO HALF OF THE CONSENSUS OPERATOR SEQUENCE
Descriptor: HALF CONSENSUS DNA OPERATOR DUPLEX, METHIONINE REPRESSOR
Authors:Garvie, C.W, Phillips, S.E.V.
Deposit date:1998-01-30
Release date:1999-08-02
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Direct and indirect readout in mutant Met repressor-operator complexes.
Structure Fold.Des., 8, 2000
1MJO
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BU of 1mjo by Molmil
METHIONINE HOLOREPRESSOR MUTANT (Q44K) PLUS COREPRESSOR (S-ADENOSYL METHIONINE) COMPLEXED TO THE MINIMAL MET CONSENSUS OPERATOR WITH THE CENTRAL TA STEP MUTATED TO AT
Descriptor: CALCIUM ION, CONSENSUS DNA OPERATOR DUPLEX WITH THE CENTRAL TA STEP MUTATED TO AT, METHIONINE REPRESSOR, ...
Authors:Garvie, C.W, Phillips, S.E.V.
Deposit date:1998-01-28
Release date:1999-08-02
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Direct and indirect readout in mutant Met repressor-operator complexes.
Structure Fold.Des., 8, 2000
1MJ2
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BU of 1mj2 by Molmil
METHIONINE REPRESSOR MUTANT (Q44K) PLUS COREPRESSOR (S-ADENOSYL METHIONINE) COMPLEXED TO A CONSENSUS OPERATOR SEQUENCE
Descriptor: CALCIUM ION, DNA (5'-D(*TP*TP*AP*GP*AP*CP*GP*TP*CP*TP*AP*GP*AP*CP*GP*TP*CP*TP*A)-3'), PROTEIN (METHIONINE REPRESSOR), ...
Authors:Garvie, C.W, Phillips, S.E.V.
Deposit date:1998-01-27
Release date:1999-08-02
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Direct and indirect readout in mutant Met repressor-operator complexes.
Structure Fold.Des., 8, 2000
7LRD
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BU of 7lrd by Molmil
Cryo-EM of the SLFN12-PDE3A complex: Consensus subset model
Descriptor: (4~{R})-3-[4-(diethylamino)-3-[oxidanyl(oxidanylidene)-$l^{4}-azanyl]phenyl]-4-methyl-4,5-dihydro-1~{H}-pyridazin-6-one, MAGNESIUM ION, MANGANESE (II) ION, ...
Authors:Fuller, J.R, Garvie, C.W, Lemke, C.T.
Deposit date:2021-02-16
Release date:2021-06-09
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.22 Å)
Cite:Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase.
Nat Commun, 12, 2021
7LRE
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BU of 7lre by Molmil
Cryo-EM of the SLFN12-PDE3A complex: SLFN12 body refinement
Descriptor: Schlafen family member 12, ZINC ION
Authors:Fuller, J.R, Garvie, C.W, Lemke, C.T.
Deposit date:2021-02-16
Release date:2021-06-09
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase.
Nat Commun, 12, 2021
7LRC
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BU of 7lrc by Molmil
Cryo-EM of the SLFN12-PDE3A complex: PDE3A body refinement
Descriptor: (4~{R})-3-[4-(diethylamino)-3-[oxidanyl(oxidanylidene)-$l^{4}-azanyl]phenyl]-4-methyl-4,5-dihydro-1~{H}-pyridazin-6-one, MAGNESIUM ION, MANGANESE (II) ION, ...
Authors:Fuller, J.R, Garvie, C.W, Lemke, C.T.
Deposit date:2021-02-16
Release date:2021-06-09
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase.
Nat Commun, 12, 2021
2KW3
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BU of 2kw3 by Molmil
Heterotrimeric interaction between RFX5 and RFXAP
Descriptor: DNA-binding protein RFX5, Regulatory factor X-associated protein
Authors:Laird, K.M, Briggs, L.L, Boss, J.M, Summers, M.F, Garvie, C.W.
Deposit date:2010-03-30
Release date:2010-08-25
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the heterotrimeric complex between RFX5 and RFXAP reveals molecular details associated with MHCII gene expression
To be Published
7L28
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BU of 7l28 by Molmil
Crystal structure of the catalytic domain of human PDE3A bound to Trequinsin
Descriptor: (2E)-9,10-dimethoxy-3-methyl-2-[(2,4,6-trimethylphenyl)imino]-2,3,6,7-tetrahydro-4H-pyrimido[6,1-a]isoquinolin-4-one, ACETATE ION, MAGNESIUM ION, ...
Authors:Horner, S.W, Garvie, C.
Deposit date:2020-12-16
Release date:2021-06-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase.
Nat Commun, 12, 2021
7L29
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BU of 7l29 by Molmil
Crystal structure of the catalytic domain of human PDE3A bound to AMP
Descriptor: ACETATE ION, ADENOSINE MONOPHOSPHATE, CALCIUM ION, ...
Authors:Horner, S.W, Garvie, C.
Deposit date:2020-12-16
Release date:2021-06-16
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase.
Nat Commun, 12, 2021
7L27
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BU of 7l27 by Molmil
Crystal structure of the catalytic domain of human PDE3A
Descriptor: ACETATE ION, CALCIUM ION, MAGNESIUM ION, ...
Authors:Horner, S.W, Garvie, C.
Deposit date:2020-12-16
Release date:2021-06-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase.
Nat Commun, 12, 2021
7KWE
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BU of 7kwe by Molmil
Crystal structure of the catalytic domain of human PDE3A bound to DNMDP
Descriptor: (4~{R})-3-[4-(diethylamino)-3-[oxidanyl(oxidanylidene)-$l^{4}-azanyl]phenyl]-4-methyl-4,5-dihydro-1~{H}-pyridazin-6-one, ACETATE ION, MAGNESIUM ION, ...
Authors:Horner, S.W, Garvie, C.
Deposit date:2020-11-30
Release date:2021-06-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase.
Nat Commun, 12, 2021

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