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8QY4
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BU of 8qy4 by Molmil
Structure of interleukin 11 (gp130 P496L mutant).
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-11, ...
Authors:Gardner, S, Bubeck, D, Jin, Y.
Deposit date:2023-10-25
Release date:2024-02-21
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Structure of interleukin 11 (gp130 P496L mutant).
To Be Published
8QY5
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BU of 8qy5 by Molmil
Structure of interleukin 6.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-6, ...
Authors:Gardner, S, Bubeck, D, Jin, Y.
Deposit date:2023-10-25
Release date:2024-02-21
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure of interleukin 6.
To Be Published
8QY6
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BU of 8qy6 by Molmil
Structure of interleukin 6 (gp130 P496L mutant).
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-6, ...
Authors:Gardner, S, Bubeck, D, Jin, Y.
Deposit date:2023-10-25
Release date:2024-02-21
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:Structure of interleukin 6 (gp130 P496L mutant).
To Be Published
8BA8
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BU of 8ba8 by Molmil
CryoEM structure of GroEL-ADP.BeF3-Rubisco.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chaperonin GroEL, ...
Authors:Gardner, S, Saibil, H.R.
Deposit date:2022-10-11
Release date:2023-12-27
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis of substrate progression through the bacterial chaperonin cycle.
Proc Natl Acad Sci U S A, 120, 2023
8BA9
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BU of 8ba9 by Molmil
CryoEM structure of GroEL-GroES-ADP.AlF3-Rubisco.
Descriptor: 60 kDa chaperonin, ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, ...
Authors:Gardner, S, Saibil, H.R.
Deposit date:2022-10-11
Release date:2023-12-27
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis of substrate progression through the bacterial chaperonin cycle.
Proc Natl Acad Sci U S A, 120, 2023
8BA7
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BU of 8ba7 by Molmil
CryoEM structure of nucleotide-free GroEL-Rubisco.
Descriptor: Chaperonin GroEL
Authors:Gardner, S, Saibil, H.R.
Deposit date:2022-10-11
Release date:2023-10-25
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structural basis of substrate progression through the bacterial chaperonin cycle.
Proc.Natl.Acad.Sci.USA, 120, 2023
6UL7
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BU of 6ul7 by Molmil
Structure of human ketohexokinase-C in complex with fructose, NO3, and osthole
Descriptor: 7-methoxy-8-(3-methylbut-2-enyl)chromen-2-one, Ketohexokinase, NITRATE ION, ...
Authors:Gasper, W.C, Gardner, S, Allen, K.N, Tolan, D.R.
Deposit date:2019-10-07
Release date:2021-04-07
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of human ketohexokinase-C in complex with fructose, NO3, and osthole
To be Published
7Z0L
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BU of 7z0l by Molmil
IL-27 signalling complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-27 receptor subunit alpha, ...
Authors:Jin, Y, Gardner, S, Bubeck, D.
Deposit date:2022-02-23
Release date:2022-07-27
Last modified:2022-10-19
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural insights into the assembly and activation of the IL-27 signaling complex.
Embo Rep., 23, 2022
6H03
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BU of 6h03 by Molmil
OPEN CONFORMATION OF THE MEMBRANE ATTACK COMPLEX
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C5,Complement C5, ...
Authors:Menny, A, Serna, M, Boyd, C.M, Gardner, S, Joseph, A.P, Topf, M, Bubeck, D.
Deposit date:2018-07-06
Release date:2018-12-19
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (5.6 Å)
Cite:CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers.
Nat Commun, 9, 2018
6H04
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BU of 6h04 by Molmil
Closed conformation of the Membrane Attack Complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C5,Complement C5, ...
Authors:Menny, A, Serna, M, Boyd, C.M, Gardner, S, Joseph, A.P, Topf, M, Bubeck, D.
Deposit date:2018-07-06
Release date:2018-12-19
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (5.6 Å)
Cite:CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers.
Nat Commun, 9, 2018
8B0H
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BU of 8b0h by Molmil
2C9, C5b9-CD59 cryoEM structure
Descriptor: CD59 glycoprotein, Complement C5, Complement component C6, ...
Authors:Couves, E.C, Gardner, S, Bubeck, D.
Deposit date:2022-09-07
Release date:2023-02-22
Last modified:2023-03-01
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis for membrane attack complex inhibition by CD59.
Nat Commun, 14, 2023
8B0G
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BU of 8b0g by Molmil
2C9, C5b9-CD59 structure
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD59 glycoprotein, Complement C5, ...
Authors:Couves, E.C, Gardner, S, Bubeck, D.
Deposit date:2022-09-07
Release date:2023-02-22
Last modified:2023-03-01
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis for membrane attack complex inhibition by CD59.
Nat Commun, 14, 2023
8B0F
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BU of 8b0f by Molmil
CryoEM structure of C5b8-CD59
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Bubeck, D, Couves, E.C, Gardner, S.
Deposit date:2022-09-07
Release date:2023-02-22
Last modified:2023-03-01
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis for membrane attack complex inhibition by CD59.
Nat Commun, 14, 2023
8G0L
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BU of 8g0l by Molmil
Semi-synthetic CoA-alpha-Synuclein Constructs Trap N-terminal Acetyltransferase NatB for Binding Mechanism Studies
Descriptor: Alpha-synuclein, CARBOXYMETHYL COENZYME *A, N-alpha-acetyltransferase 20, ...
Authors:Gardner, S.M, Marmorstein, R.
Deposit date:2023-01-31
Release date:2023-05-03
Method:ELECTRON MICROSCOPY (3.39 Å)
Cite:Semi-synthetic CoA-alpha-Synuclein Constructs Trap N-terminal Acetyltransferase NatB for Binding Mechanism Studies.
Biorxiv, 2023
6P2D
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BU of 6p2d by Molmil
Structure of mouse ketohexokinase-C in complex with fructose and ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Ketohexokinase, beta-D-fructofuranose
Authors:Gasper, W.C, Allen, K.N, Tolan, D.R.
Deposit date:2019-05-21
Release date:2020-06-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.794 Å)
Cite:First Crystal Structure of Mouse Ketohexokinase-C (KHK-C) Confirms Structural Similarity to Human KHK-C and Suggests Alternate Confirmation May Be Linked to Catalysis
To be published
7KJE
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BU of 7kje by Molmil
F96S epi-isozizaene synthase: complex with 3 Mg2+ and neridronate
Descriptor: (6-azanyl-1-oxidanyl-1-phosphono-hexyl)phosphonic acid, MAGNESIUM ION, SULFATE ION, ...
Authors:Ronnebaum, T.A, Gardner, S, Christianson, D.W.
Deposit date:2020-10-26
Release date:2020-12-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:An Aromatic Cluster in the Active Site of epi -Isozizaene Synthase Is an Electrostatic Toggle for Divergent Terpene Cyclization Pathways.
Biochemistry, 59, 2020
8C6I
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BU of 8c6i by Molmil
TMEM2 ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Hohenester, E.
Deposit date:2023-01-11
Release date:2023-02-01
Last modified:2023-06-07
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of the transmembrane protein 2 (TMEM2) ectodomain and its apparent lack of hyaluronidase activity.
Wellcome Open Res, 8, 2023

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PDB entries from 2024-03-27

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