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4MGR
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THE CRYSTAL STRUCTURE OF BACILLUS SUBTILIS GABR, AN AUTOREPRESSOR AND PLP- AND GABA-DEPENDENT TRANSCRIPTIONAL ACTIVATOR OF GABT
Descriptor:HTH-type transcriptional regulatory protein GabR, ZINC ION, IMIDAZOLE, ...
Authors:Wu, R., Edayathumangalam, R., Garcia, R., Wang, Y., Wang, W., Kreinbring, C.A., Bach, A., Liao, J., Stone, T., Terwilliger, T., Hoang, Q.Q., Belitsky, B.R., Petsko, G.A., Ringe, D., Liu, D.
Deposit date:2013-08-28
Release date:2013-10-30
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal structure of Bacillus subtilis GabR, an autorepressor and transcriptional activator of gabT.
Proc.Natl.Acad.Sci.USA, 110, 2013
4N0B
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CRYSTAL STRUCTURE OF BACILLUS SUBTILIS GABR, AN AUTOREPRESSOR AND TRANSCRIPTIONAL ACTIVATOR OF GABT
Descriptor:HTH-type transcriptional regulatory protein GabR, ACETYL GROUP, ZINC ION, ...
Authors:Edayathumangalam, R., Wu, R., Garcia, R., Wang, Y., Wang, W., Kreinbring, C.A., Bach, A., Liao, J., Stone, T., Terwilliger, T., Hoang, Q.Q., Belitsky, B.R., Petsko, G.A., Ringe, D., Liu, D.
Deposit date:2013-10-01
Release date:2013-10-30
Last modified:2014-04-02
Method:X-RAY DIFFRACTION (2.705 Å)
Cite:Crystal structure of Bacillus subtilis GabR, an autorepressor and transcriptional activator of gabT.
Proc.Natl.Acad.Sci.USA, 110, 2013
1IAI
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IDIOTYPE-ANTI-IDIOTYPE FAB COMPLEX
Descriptor:IDIOTYPIC FAB 730.1.4 (IGG1) OF VIRUS NEUTRALIZING ANTIBODY, ANTI-IDIOTYPIC FAB 409.5.3 (IGG2A)
Authors:Ban, N., Escobar, C., Garcia, R., Hasel, K., Day, J., Greenwood, A., McPherson, A.
Deposit date:1993-12-28
Release date:1996-03-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of an idiotype-anti-idiotype Fab complex.
Proc.Natl.Acad.Sci.USA, 91, 1994
2BGD
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STRUCTURE-BASED DESIGN OF PROTEIN TYROSINE PHOSPHATASE-1B INHIBITORS
Descriptor:PROTEIN-TYROSINE PHOSPHATASE NON-RECEPTOR TYPE 1, 5-(4-METHOXYBIPHENYL-3-YL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE, CHLORIDE ION, ...
Authors:Black, E., Breed, J., Breeze, A.L., Embrey, K., Garcia, R., Gero, T.W., Godfrey, L., Kenny, P.W., Morley, A.D., Minshull, C.A., Pannifer, A.D., Read, J., Rees, A., Russell, D.J., Toader, D., Tucker, J.
Deposit date:2004-12-21
Release date:2005-05-04
Last modified:2015-09-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure-Based Design of Protein Tyrosine Phosphatase-1B Inhibitors
Bioorg.Med.Chem.Lett., 15, 2005
2BGE
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STRUCTURE-BASED DESIGN OF PROTEIN TYROSINE PHOSPHATASE-1B INHIBITORS
Descriptor:PROTEIN-TYROSINE PHOSPHATASE NON-RECEPTOR TYPE 1, 1,2,5-THIADIAZOLIDIN-3-ONE-1,1-DIOXIDE
Authors:Black, E., Breed, J., Breeze, A.L., Embrey, K., Garcia, R., Gero, T.W., Godfrey, L., Kenny, P.W., Morley, A.D., Minshull, C.A., Pannifer, A.D., Read, J., Rees, A., Russell, D.J., Toader, D., Tucker, J.
Deposit date:2004-12-21
Release date:2005-05-04
Last modified:2015-10-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure-Based Design of Protein Tyrosine Phosphatase-1B Inhibitors
Bioorg.Med.Chem.Lett., 15, 2005
5JH7
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TUBULIN-ERIBULIN COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Doodhi, H., Prota, A.E., Rodriguez-Garcia, R., Xiao, H., Custar, D.W., Bargsten, K., Katrukha, E.A., Hilbert, M., Hua, S., Jiang, K., Grigoriev, I., Yang, C.-P.H., Cox, D., Band Horwitz, S., Kapitein, L.C., Akhmanova, A., Steinmetz, M.O.
Deposit date:2016-04-20
Release date:2016-06-29
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Termination of Protofilament Elongation by Eribulin Induces Lattice Defects that Promote Microtubule Catastrophes.
Curr.Biol., 26, 2016
6FGB
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HUMAN FCRN EXTRA-CELLULAR DOMAIN COMPLEXED WITH FAB FRAGMENT OF ROZANOLIXIZUMAB
Descriptor:IgG receptor FcRn large subunit p51, Beta-2-microglobulin, 1519.g57- Light chain, ...
Authors:Sarkar, K., Ceska, T., Meier, C.
Deposit date:2018-01-10
Release date:2018-08-29
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Generation and characterization of a high affinity anti-human FcRn antibody, rozanolixizumab, and the effects of different molecular formats on the reduction of plasma IgG concentration.
MAbs, 10, 2018
5NR4
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CRYSTAL STRUCTURE OF CLASP2 TOG1 DOMAIN
Descriptor:CLIP-associating protein 2
Authors:Sharma, A., Olieric, N., Weinert, T., Olieric, V., Steinmetz, M.O.
Deposit date:2017-04-21
Release date:2018-05-30
Last modified:2018-07-18
Method:X-RAY DIFFRACTION (1.198 Å)
Cite:CLASP Suppresses Microtubule Catastrophes through a Single TOG Domain.
Dev. Cell, 46, 2018
1AIF
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ANTI-IDIOTYPIC FAB 409.5.3 (IGG2A) FAB FROM MOUSE
Descriptor:ANTI-IDIOTYPIC FAB 409.5.3 (IGG2A) FAB (LIGHT CHAIN), ANTI-IDIOTYPIC FAB 409.5.3 (IGG2A) FAB (HEAVY CHAIN)
Authors:Ban, N., Escobar, C., Hasel, K., Day, J., Greenwood, A., McPherson, A.
Deposit date:1994-11-14
Release date:1997-02-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of an anti-idiotypic Fab against feline peritonitis virus-neutralizing antibody and a comparison with the complexed Fab.
FASEB J., 9, 1995