Author results

2WYL
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APO STRUCTURE OF A METALLO-B-LACTAMASE
Descriptor:L-ASCORBATE-6-PHOSPHATE LACTONASE ULAG, GLYCEROL, FORMYL GROUP
Authors:Garces, F., Fernandez, F.J., Penya-Soler, E., Aguilar, J., Baldoma, L., Coll, M., Badia, J., Vega, M.C.
Deposit date:2009-11-16
Release date:2010-04-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Molecular Architecture of the Mn(2+)Dependent Lactonase Ulag Reveals an Rnase-Like Metallo-Beta-Lactamase Fold and a Novel Quaternary Structure.
J.Mol.Biol., 398, 2010
2WYM
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STRUCTURE OF A METALLO-B-LACTAMASE
Descriptor:L-ASCORBATE-6-PHOSPHATE LACTONASE ULAG, MANGANESE (II) ION, GLYCEROL, ...
Authors:Garces, F., Fernandez, F.J., Penya-Soler, E., Aguilar, J., Baldoma, L., Coll, M., Badia, J., Vega, M.C.
Deposit date:2009-11-16
Release date:2010-04-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular Architecture of the Mn(2+)Dependent Lactonase Ulag Reveals an Rnase-Like Metallo-Beta-Lactamase Fold and a Novel Quaternary Structure.
J.Mol.Biol., 398, 2010
3ZVL
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THE STRUCTURAL BASIS FOR SUBSTRATE RECOGNITION BY MAMMALIAN POLYNUCLEOTIDE KINASE 3' PHOSPHATASE
Descriptor:BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE, GLYCEROL, MAGNESIUM ION, ...
Authors:Garces, F., Pearl, L.H., Oliver, A.W.
Deposit date:2011-07-25
Release date:2011-11-16
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The Structural Basis for Substrate Recognition by Mammalian Polynucleotide Kinase 3' Phosphatase.
Mol.Cell, 44, 2011
3ZVM
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THE STRUCTURAL BASIS FOR SUBSTRATE RECOGNITION BY MAMMALIAN POLYNUCLEOTIDE KINASE 3' PHOSPHATASE
Descriptor:BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE, 5'-D(*GP*TP*CP*AP*CP)-3', ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Garces, F., Pearl, L.H., Oliver, A.W.
Deposit date:2011-07-25
Release date:2011-11-16
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.997 Å)
Cite:The structural basis for substrate recognition by mammalian polynucleotide kinase 3' phosphatase.
Mol. Cell, 44, 2011
3ZVN
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THE STRUCTURAL BASIS FOR SUBSTRATE RECOGNITION BY MAMMALIAN POLYNUCLEOTIDE KINASE 3' PHOSPHATASE
Descriptor:BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE, 5'-D(*GP*TP*CP*AP*CP)-3', MANGANESE (II) ION, ...
Authors:Garces, F., Pearl, L.H., Oliver, A.W.
Deposit date:2011-07-25
Release date:2011-11-16
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The structural basis for substrate recognition by mammalian polynucleotide kinase 3' phosphatase.
Mol. Cell, 44, 2011
4R26
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CRYSTAL STRUCTURE OF HUMAN FAB PGT124, A BROADLY NEUTRALIZING AND POTENT HIV-1 NEUTRALIZING ANTIBODY
Descriptor:PGR124-Light Chain, PGT124-Heavy Chain, GLYCEROL
Authors:Garces, F., Kong, L., Wilson, I.A.
Deposit date:2014-08-08
Release date:2014-10-08
Last modified:2017-06-21
Method:X-RAY DIFFRACTION (2.4969 Å)
Cite:Structural Evolution of Glycan Recognition by a Family of Potent HIV Antibodies.
Cell(Cambridge,Mass.), 159, 2014
4R2G
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CRYSTAL STRUCTURE OF PGT124 FAB BOUND TO HIV-1 JRCSF GP120 CORE AND TO CD4
Descriptor:Surface protein gp160, T-cell surface glycoprotein CD4, PGT124 Light Chain, ...
Authors:Garces, F., Wilson, I.A.
Deposit date:2014-08-11
Release date:2014-10-08
Last modified:2017-06-21
Method:X-RAY DIFFRACTION (3.283 Å)
Cite:Structural Evolution of Glycan Recognition by a Family of Potent HIV Antibodies.
Cell(Cambridge,Mass.), 159, 2014
5CEX
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CRYSTAL STRUCTURE OF FAB 32H+109L, A PUTATIVE PRECURSOR OF THE PGT121 FAMILY OF POTENT HIV-1 ANTIBODIES
Descriptor:Antibody 9H+3L Fab light chain, Antibody 9H+3L Fab heavy chain, TETRAETHYLENE GLYCOL, ...
Authors:Garces, F., Wilson, I.A.
Deposit date:2015-07-07
Release date:2015-12-23
Last modified:2016-01-06
Method:X-RAY DIFFRACTION (2.105 Å)
Cite:Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans.
Immunity, 43, 2015
5BZD
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CRYSTAL STRUCTURE OF PCDN-27A, AN ANTIBODY FROM THE PCDN FAMILY OF HIV-1 ANTIBODIES
Descriptor:5G8 HIV Antibody light chain, 5G8 HIV Antibody heavy chain, GLYCEROL
Authors:Garces, F., WILSON, I.A.
Deposit date:2015-06-11
Release date:2016-05-25
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch
Immunity, 44, 2016
5BZW
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CRYSTAL STRUCTURE OF PCDN-27B, AN ANTIBODY FROM THE PCDN FAMILY OF HIV-1 ANTIBODIES
Descriptor:2B3 HIV Antibody light chain, 2B3 HIV Antibody heavy chain, SULFATE ION, ...
Authors:Garces, F., WILSON, I.A.
Deposit date:2015-06-11
Release date:2016-05-25
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch.
Immunity, 44, 2016
5CEY
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CRYSTAL STRUCTURE OF FAB 9H+3L, A PUTATIVE PRECURSOR OF THE PGT121 FAMILY OF POTENT HIV-1 ANTIBODIES
Descriptor:Antibody 9H+3L Fab light chain, Antibody 9H+3L Fab heavy chain, GLYCEROL, ...
Authors:Wilson, I.A., Garces, F.
Deposit date:2015-07-07
Release date:2015-12-23
Last modified:2016-01-06
Method:X-RAY DIFFRACTION (2.387 Å)
Cite:Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans.
Immunity, 43, 2015
5CEZ
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CRYSTAL STRUCTURE OF THE BG505 SOSIP GP140 HIV-1 ENV TRIMER IN COMPLEX WITH AN EARLY PUTATIVE PRECURSOR OF THE PGT121 FAMILY AT 3.0 ANGSTROM
Descriptor:Envelope glycoprotein gp160, 3H+109L Fab Light Chain, 3H+109L Fab Heavy Chain, ...
Authors:Wilson, I.A., Garces, F.
Deposit date:2015-07-08
Release date:2015-12-23
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (3.031 Å)
Cite:Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans.
Immunity, 43, 2015
5UM8
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CRYSTAL STRUCTURE OF HIV-1 ENVELOPE TRIMER 16055 NFL TD CC (T569G) IN COMPLEX WITH FABS 35022 AND PGT124
Descriptor:glycoprotein gp120, glycoprotein gp41, Fab PGT124 light chain, ...
Authors:Garces, F., Stanfield, R.L., Wilson, I.A.
Deposit date:2017-01-26
Release date:2017-05-24
Last modified:2017-06-21
Method:X-RAY DIFFRACTION (3.935 Å)
Cite:Glycine Substitution at Helix-to-Coil Transitions Facilitates the Structural Determination of a Stabilized Subtype C HIV Envelope Glycoprotein.
Immunity, 46, 2017
5W6D
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CRYSTAL STRUCTURE OF BG505-SOSIP.V4.1-GT1-N137A IN COMPLEX WITH FABS 35022 AND 9H/109L
Descriptor:BG505-SOSIP.v4.1-GT1-N137A gp120, BG505-SOSIP.v4.1-GT1-N137A gp41, 109L FAB light chain, ...
Authors:Garces, F., Stanfield, R.L., Wilson, I.A.
Deposit date:2017-06-16
Release date:2017-07-05
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3.202 Å)
Cite:Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo.
J. Exp. Med., 214, 2017
5NQ6
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CRYSTAL STRUCTURE OF THE INHIBITED FORM OF THE REDOX-SENSITIVE SUFE-LIKE SULFUR ACCEPTOR CSDE FROM ESCHERICHIA COLI AT 2.40 ANGSTROM RESOLUTION
Descriptor:Sulfur acceptor protein CsdE, GLYCEROL, SULFATE ION
Authors:Penya-Soler, E., Aranda, J., Lopez-Estepa, M., Gomez, S., Garces, F., Coll, M., Fernandez, F.J., Vega, M.C.
Deposit date:2017-04-19
Release date:2018-03-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Insights into the inhibited form of the redox-sensitive SufE-like sulfur acceptor CsdE.
PLoS ONE, 12, 2017
4CVQ
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CRYSTAL STRUCTURE OF AN AMINOTRANSFERASE FROM ESCHERICHIA COLI AT 2. 11 ANGSTROEM RESOLUTION
Descriptor:GLUTAMATE-PYRUVATE AMINOTRANSFERASE ALAA, PYRIDOXAL-5'-PHOSPHATE, ACETATE ION, ...
Authors:Penya-Soler, E., Fernandez, F.J., Lopez-Estepa, M., Garces, F., Richardson, A.J., Rudd, K.E., Coll, M., Vega, M.C.
Deposit date:2014-03-28
Release date:2014-07-23
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Structural analysis and mutant growth properties reveal distinctive enzymatic and cellular roles for the three major L-alanine transaminases of Escherichia coli.
PLoS ONE, 9, 2014
5FT4
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CRYSTAL STRUCTURE OF THE CYSTEINE DESULFURASE CSDA FROM ESCHERICHIA COLI AT 1.996 ANGSTROEM RESOLUTION
Descriptor:CYSTEINE DESULFURASE CSDA, PYRIDOXAL-5'-PHOSPHATE, GLYCEROL, ...
Authors:Fernandez, F.J., Arda, A., Lopez-Estepa, M., Aranda, J., Penya-Soler, E., Garces, F., Quintana, J.F., Round, A., Campos-Oliva, R., Bruix, M., Coll, M., Tunon, I., Jimenez-Barbero, J., Vega, M.C.
Deposit date:2016-01-11
Release date:2016-12-21
Last modified:2019-01-02
Method:X-RAY DIFFRACTION (1.996 Å)
Cite:The Mechanism of Sulfur Transfer Across Protein- Protein Interfaces: The Csd Model
Acs Catalysis, 6, 2016
5FT5
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CRYSTAL STRUCTURE OF THE CYSTEINE DESULFURASE CSDA (PERSULFURATED) FROM ESCHERICHIA COLI AT 2.384 ANGSTROEM RESOLUTION
Descriptor:L-CYSTEINE DESULFURASE CSDA, GLYCEROL, DI(HYDROXYETHYL)ETHER, ...
Authors:Fernandez, F.J., Arda, A., Lopez-Estepa, M., Aranda, J., Penya-Soler, E., Garces, F., Quintana, J.F., Round, A., Campos-Oliva, R., Bruix, M., Coll, M., Tunon, I., Jimenez-Barbero, J., Vega, M.C.
Deposit date:2016-01-11
Release date:2016-11-23
Last modified:2019-01-02
Method:X-RAY DIFFRACTION (2.384 Å)
Cite:Mechanism of Sulfur Transfer Across Protein-Protein Interfaces: The Cysteine Desulfurase Model System
Acs Catalysis, 6, 2016
5FT6
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CRYSTAL STRUCTURE OF THE CYSTEINE DESULFURASE CSDA (S-SULFONIC ACID) FROM ESCHERICHIA COLI AT 2.050 ANGSTROEM RESOLUTION
Descriptor:CYSTEINE DESULFURASE CSDA, GLYCEROL, DI(HYDROXYETHYL)ETHER, ...
Authors:Fernandez, F.J., Arda, A., Lopez-Estepa, M., Aranda, J., Penya-Soler, E., Garces, F., Round, A., Campos-Oliva, R., Bruix, M., Coll, M., Tunon, I., Jimenez-Barbero, J., Vega, M.C.
Deposit date:2016-01-11
Release date:2016-11-23
Last modified:2019-01-02
Method:X-RAY DIFFRACTION (2.049 Å)
Cite:Mechanism of Sulfur Transfer Across Protein-Protein Interfaces: The Cysteine Desulfurase Model System
Acs Catalysis, 6, 2016
5FT8
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CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE CYSTEINE DESULFURASE CSDA AND THE SULFUR-ACCEPTOR CSDE IN THE PERSULFURATED STATE AT 2.50 ANGSTROEM RESOLUTION
Descriptor:CYSTEINE DESULFURASE CSDA, SULFUR ACCEPTOR PROTEIN CSDE, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Fernandez, F.J., Arda, A., Lopez-Estepa, M., Aranda, J., Penya-Soler, E., Garces, F., Round, A., Campos-Oliva, R., Bruix, M., Coll, M., Tunon, I., Jimenez-Barbero, J., Vega, M.C.
Deposit date:2016-01-11
Release date:2016-11-23
Last modified:2019-01-02
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mechanism of Sulfur Transfer Across Protein-Protein Interfaces: The Cysteine Desulfurase Model System
Acs Catalysis, 6, 2016
4RNR
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CRYSTAL STRUCTURE OF BROADLY NEUTRALIZING ANTI-HIV ANTIBODY PGT130
Descriptor:PGT130 Heavy Chain, PGT130 Light Chain, N-ACETYL-D-GLUCOSAMINE
Authors:Kong, L., Wilson, I.A.
Deposit date:2014-10-24
Release date:2014-11-19
Last modified:2015-01-28
Method:X-RAY DIFFRACTION (2.758 Å)
Cite:Two Classes of Broadly Neutralizing Antibodies within a Single Lineage Directed to the High-Mannose Patch of HIV Envelope.
J.Virol., 89, 2015
5C7K
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CRYSTAL STRUCTURE BG505 SOSIP GP140 HIV-1 ENV TRIMER BOUND TO BROADLY NEUTRALIZING ANTIBODIES PGT128 AND 8ANC195
Descriptor:Antibody Fab PGT128 heavy chain, Antibody Fab PGT128 light chain, Envelope glycoprotein gp120, ...
Authors:Kong, L., Stanfield, R.L., Wilson, I.A.
Deposit date:2015-06-24
Release date:2015-10-07
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (4.6019 Å)
Cite:Complete epitopes for vaccine design derived from a crystal structure of the broadly neutralizing antibodies PGT128 and 8ANC195 in complex with an HIV-1 Env trimer.
Acta Crystallogr.,Sect.D, 71, 2015
5CD3
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STRUCTURE OF IMMATURE VRC01-CLASS ANTIBODY DRVIA7
Descriptor:DRVIA7 Heavy Chain, DRVIA7 Light Chain
Authors:Kong, L., Wilson, I.A.
Deposit date:2015-07-02
Release date:2016-04-06
Last modified:2018-09-05
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor.
Immunity, 44, 2016
5CD5
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CRYSTAL STRUCTURE OF AN IMMATURE VRC01-CLASS ANTIBODY DRVIA7 FROM A CHINESE DONOR BOUND TO CLADE A/E HIV-1 GP120 CORE
Descriptor:93TH057 HIV-1 gp120 core, DRVIA7 Fab Heavy Chain, DRVIA7 Fab Light Chain, ...
Authors:Kong, L., Wilson, I.A.
Deposit date:2015-07-03
Release date:2016-04-06
Last modified:2018-09-05
Method:X-RAY DIFFRACTION (3.396 Å)
Cite:Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor.
Immunity, 44, 2016
5T3S
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HIV GP140 TRIMER MD39-10MUTA IN COMPLEX WITH FABS PGT124 AND 35022
Descriptor:Envelope glycoprotein gp160, Fab PGT124 light chain, Fab PGT124 heavy chain, ...
Authors:Stanfield, R.L., Wilson, I.A.
Deposit date:2016-08-26
Release date:2016-09-28
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies.
Immunity, 45, 2016
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