Author results

1PEF
  • Download 1pef
  • View 1pef
Molmil generated image of 1pef
PEPTIDE F (EQLLKALEFLLKELLEKL), AMPHIPHILIC OCTADECAPEPTIDE
Descriptor:PEPTIDE F (EQLLKALEFLLKELLEKL)
Authors:Garavito, R.M., Taylor, K., Yang, N.C.
Deposit date:1995-06-19
Release date:1996-12-07
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A novel, multilayer structure of a helical peptide.
Protein Sci., 5, 1996
2FON
  • Download 2fon
  • View 2fon
Molmil generated image of 2fon
X-RAY CRYSTAL STRUCTURE OF LEACX1, AN ACYL-COA OXIDASE FROM LYCOPERSICON ESCULENTUM (TOMATO)
Descriptor:peroxisomal acyl-CoA oxidase 1A, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Garavito, R.M., Powers, R.A.
Deposit date:2006-01-13
Release date:2006-05-23
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Structure determination and analysis of acyl-CoA oxidase (ACX1) from tomato.
Acta Crystallogr.,Sect.D, 62, 2006
1CQE
  • Download 1cqe
  • View 1cqe
Molmil generated image of 1cqe
PROSTAGLANDIN H2 SYNTHASE-1 COMPLEX WITH FLURBIPROFEN
Descriptor:PROTEIN (PROSTAGLANDIN H2 SYNTHASE-1), N-ACETYL-D-GLUCOSAMINE, B-OCTYLGLUCOSIDE, ...
Authors:Picot, D., Loll, P.J., Mulichak, A.M., Garavito, R.M.
Deposit date:1999-06-15
Release date:1999-06-30
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1.
Nature, 367, 1994
1IGX
  • Download 1igx
  • View 1igx
Molmil generated image of 1igx
CRYSTAL STRUCTURE OF EICOSAPENTANOIC ACID BOUND IN THE CYCLOOXYGENASE CHANNEL OF PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE-1.
Descriptor:Prostaglandin Endoperoxide H Synthase-1, N-ACETYL-D-GLUCOSAMINE, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ...
Authors:Malkowski, M.G., Thuresson, E.D., Smith, W.L., Garavito, R.M.
Deposit date:2001-04-18
Release date:2001-12-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of eicosapentaenoic and linoleic acids in the cyclooxygenase site of prostaglandin endoperoxide H synthase-1.
J.Biol.Chem., 276, 2001
1IGZ
  • Download 1igz
  • View 1igz
Molmil generated image of 1igz
CRYSTAL STRUCTURE OF LINOLEIC ACID BOUND IN THE CYCLOOXYGENASE CHANNEL OF PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE-1.
Descriptor:Prostaglandin Endoperoxide H Synthase-1, N-ACETYL-D-GLUCOSAMINE, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ...
Authors:Malkowski, M.G., Thuresson, E.D., Smith, W.L., Garavito, R.M.
Deposit date:2001-04-18
Release date:2001-12-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of eicosapentaenoic and linoleic acids in the cyclooxygenase site of prostaglandin endoperoxide H synthase-1.
J.Biol.Chem., 276, 2001
1PGE
  • Download 1pge
  • View 1pge
Molmil generated image of 1pge
PROSTAGLANDIN H2 SYNTHASE-1 COMPLEXED WITH P-(2'-IODO-5'-THENOYL)HYDROTROPIC ACID (IODOSUPROFEN)
Descriptor:PROSTAGLANDIN H2 SYNTHASE-1, N-ACETYL-D-GLUCOSAMINE, B-OCTYLGLUCOSIDE, ...
Authors:Loll, P.J., Picot, D., Garavito, R.M.
Deposit date:1995-12-02
Release date:1997-01-11
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Synthesis and use of iodinated nonsteroidal antiinflammatory drug analogs as crystallographic probes of the prostaglandin H2 synthase cyclooxygenase active site.
Biochemistry, 35, 1996
1PGF
  • Download 1pgf
  • View 1pgf
Molmil generated image of 1pgf
PROSTAGLANDIN H2 SYNTHASE-1 COMPLEXED WITH 1-(4-IODOBENZOYL)-5-METHOXY-2-METHYLINDOLE-3-ACETIC ACID (IODOINDOMETHACIN), CIS MODEL
Descriptor:PROSTAGLANDIN H2 SYNTHASE-1, N-ACETYL-D-GLUCOSAMINE, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Loll, P.J., Picot, D., Garavito, R.M.
Deposit date:1995-12-02
Release date:1997-01-11
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Synthesis and use of iodinated nonsteroidal antiinflammatory drug analogs as crystallographic probes of the prostaglandin H2 synthase cyclooxygenase active site.
Biochemistry, 35, 1996
1PGG
  • Download 1pgg
  • View 1pgg
Molmil generated image of 1pgg
PROSTAGLANDIN H2 SYNTHASE-1 COMPLEXED WITH 1-(4-IODOBENZOYL)-5-METHOXY-2-METHYLINDOLE-3-ACETIC ACID (IODOINDOMETHACIN), TRANS MODEL
Descriptor:PROSTAGLANDIN H2 SYNTHASE-1, N-ACETYL-D-GLUCOSAMINE, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Loll, P.J., Picot, D., Garavito, R.M.
Deposit date:1995-12-02
Release date:1997-01-11
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Synthesis and use of iodinated nonsteroidal antiinflammatory drug analogs as crystallographic probes of the prostaglandin H2 synthase cyclooxygenase active site.
Biochemistry, 35, 1996
1FE2
  • Download 1fe2
  • View 1fe2
Molmil generated image of 1fe2
CRYSTAL STRUCTURE OF DIHOMO-GAMMA-LINOLEIC ACID BOUND IN THE CYCLOOXYGENASE CHANNEL OF PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE-1.
Descriptor:PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE-1, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Thuresson, E.D., Malkowski, M.G., Lakkides, K.M., Smith, W.L., Garavito, R.M.
Deposit date:2000-07-20
Release date:2001-05-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Mutational and X-ray crystallographic analysis of the interaction of dihomo-gamma -linolenic acid with prostaglandin endoperoxide H synthases.
J.Biol.Chem., 276, 2001
1PTH
  • Download 1pth
  • View 1pth
Molmil generated image of 1pth
THE STRUCTURAL BASIS OF ASPIRIN ACTIVITY INFERRED FROM THE CRYSTAL STRUCTURE OF INACTIVATED PROSTAGLANDIN H2 SYNTHASE
Descriptor:PROSTAGLANDIN H2 SYNTHASE-1, N-ACETYL-D-GLUCOSAMINE, B-OCTYLGLUCOSIDE, ...
Authors:Loll, P.J., Picot, D., Garavito, R.M.
Deposit date:1995-04-11
Release date:1996-04-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:The structural basis of aspirin activity inferred from the crystal structure of inactivated prostaglandin H2 synthase.
Nat.Struct.Biol., 2, 1995
1BDG
  • Download 1bdg
  • View 1bdg
Molmil generated image of 1bdg
HEXOKINASE FROM SCHISTOSOMA MANSONI COMPLEXED WITH GLUCOSE
Descriptor:HEXOKINASE, ALPHA-D-GLUCOSE, SULFATE ION
Authors:Mulichak, A.M., Garavito, R.M.
Deposit date:1998-05-08
Release date:1999-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The structure of mammalian hexokinase-1.
Nat.Struct.Biol., 5, 1998
1BG3
  • Download 1bg3
  • View 1bg3
Molmil generated image of 1bg3
RAT BRAIN HEXOKINASE TYPE I COMPLEX WITH GLUCOSE AND INHIBITOR GLUCOSE-6-PHOSPHATE
Descriptor:HEXOKINASE, BETA-D-GLUCOSE, ALPHA-D-GLUCOSE-6-PHOSPHATE, ...
Authors:Mulichak, A.M., Garavito, R.M.
Deposit date:1998-06-04
Release date:1999-06-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The structure of mammalian hexokinase-1.
Nat.Struct.Biol., 5, 1998
1DIY
  • Download 1diy
  • View 1diy
Molmil generated image of 1diy
CRYSTAL STRUCTURE OF ARACHIDONIC ACID BOUND IN THE CYCLOOXYGENASE ACTIVE SITE OF PGHS-1
Descriptor:PROSTAGLANDIN H2 SYNTHASE-1, N-ACETYL-D-GLUCOSAMINE, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ...
Authors:Malkowski, M.G., Ginell, S.L., Smith, W.L., Garavito, R.M.
Deposit date:1999-11-30
Release date:2000-09-22
Last modified:2018-05-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:The productive conformation of arachidonic acid bound to prostaglandin synthase.
Science, 289, 2000
1I24
  • Download 1i24
  • View 1i24
Molmil generated image of 1i24
HIGH RESOLUTION CRYSTAL STRUCTURE OF THE WILD-TYPE PROTEIN SQD1, WITH NAD AND UDP-GLUCOSE
Descriptor:SULFOLIPID BIOSYNTHESIS PROTEIN SQD1, SULFATE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Theisen, M.J., Sanda, S.L., Ginell, S.L., Benning, C., Garavito, R.M.
Deposit date:2001-02-05
Release date:2003-07-01
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Characterization of the Active Site of Udp-Sulfoquinovose Synthase: Formation of the Sulfonic Acid Product in the Crystalline State
To be Published
1I2B
  • Download 1i2b
  • View 1i2b
Molmil generated image of 1i2b
CRYSTAL STRUCTURE OF MUTANT T145A SQD1 PROTEIN COMPLEX WITH NAD AND UDP-SULFOQUINOVOSE/UDP-GLUCOSE
Descriptor:SULFOLIPID BIOSYNTHESIS PROTEIN SQD1, SULFATE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Theisen, M.J., Sanda, S.L., Ginell, S.L., Benning, C., Garavito, R.M.
Deposit date:2001-02-07
Release date:2003-07-01
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Characterization of the Active Site of UDP-sulfoquinovose Synthase: Formation of the Sulfonic Acid Product in the Crystalline State
To be Published
1I2C
  • Download 1i2c
  • View 1i2c
Molmil generated image of 1i2c
CRYSTAL STRUCTURE OF MUTANT T145A SQD1 PROTEIN COMPLEX WITH NAD AND UDP-GLUCOSE
Descriptor:SULFOLIPID BIOSYNTHESIS PROTEIN SQD1, SULFATE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Theisen, M.J., Sanda, S.L., Ginell, S.L., Benning, C., Garavito, R.M.
Deposit date:2001-02-07
Release date:2003-07-01
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Characterization of the Active Site of UDP-sulfoquinovose Synthase: Formation of the Sulfonic Acid Product in the Crystalline State.
To be Published
1IIR
  • Download 1iir
  • View 1iir
Molmil generated image of 1iir
CRYSTAL STRUCTURE OF UDP-GLUCOSYLTRANSFERASE GTFB
Descriptor:glycosyltransferase GtfB, SULFATE ION, MAGNESIUM ION
Authors:Mulichak, A.M., Losey, H.C., Walsh, C.T., Garavito, R.M.
Deposit date:2001-04-24
Release date:2001-07-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of the UDP-glucosyltransferase GtfB that modifies the heptapeptide aglycone in the biosynthesis of vancomycin group antibiotics.
Structure, 9, 2001
1N7G
  • Download 1n7g
  • View 1n7g
Molmil generated image of 1n7g
CRYSTAL STRUCTURE OF THE GDP-MANNOSE 4,6-DEHYDRATASE TERNARY COMPLEX WITH NADPH AND GDP-RHAMNOSE.
Descriptor:GDP-D-mannose-4,6-dehydratase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, GUANOSINE-5'-DIPHOSPHATE-RHAMNOSE
Authors:Mulichak, A.M., Bonin, C.P., Reiter, W.-D., Garavito, R.M.
Deposit date:2002-11-14
Release date:2003-01-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure of the MUR1 GDP-mannose 4,6-dehydratase from A. thaliana: Implications for ligand binding and specificity.
Biochemistry, 41, 2002
1N7H
  • Download 1n7h
  • View 1n7h
Molmil generated image of 1n7h
CRYSTAL STRUCTURE OF GDP-MANNOSE 4,6-DEHYDRATASE TERNARY COMPLEX WITH NADPH AND GDP
Descriptor:GDP-D-mannose-4,6-dehydratase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, GUANOSINE-5'-DIPHOSPHATE
Authors:Mulichak, A.M., Bonin, C.P., Reiter, W.-D., Garavito, R.M.
Deposit date:2002-11-14
Release date:2003-01-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structure of the MUR1 GDP-mannose 4,6-dehydratase from A. thaliana: Implications for ligand binding and specificity.
Biochemistry, 41, 2002
1PN3
  • Download 1pn3
  • View 1pn3
Molmil generated image of 1pn3
CRYSTAL STRUCTURE OF TDP-EPI-VANCOSAMINYLTRANSFERASE GTFA IN COMPLEXES WITH TDP AND THE ACCEPTOR SUBSTRATE DVV.
Descriptor:GLYCOSYLTRANSFERASE GTFA, DESVANCOSAMINYL VANCOMYCIN, THYMIDINE-5'-DIPHOSPHATE, ...
Authors:Mulichak, A.M., Losey, H.C., Lu, W., Wawrzak, Z., Walsh, C.T., Garavito, R.M.
Deposit date:2003-06-12
Release date:2003-08-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the Tdp-Epi-Vancosaminyltransferase Gtfa from the Chloroeremomycin Biosynthetic Pathway.
Proc.Natl.Acad.Sci.USA, 100, 2003
1PNV
  • Download 1pnv
  • View 1pnv
Molmil generated image of 1pnv
CRYSTAL STRUCTURE OF TDP-EPI-VANCOSAMINYLTRANSFERASE GTFA IN COMPLEXES WITH TDP AND VANCOMYCIN
Descriptor:GLYCOSYLTRANSFERASE GTFA, VANCOMYCIN, THYMIDINE-5'-DIPHOSPHATE, ...
Authors:Mulichak, A.M., Losey, H.C., Lu, W., Wawrzak, Z., Walsh, C.T., Garavito, R.M.
Deposit date:2003-06-13
Release date:2003-08-12
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the Tdp-Epi-Vancosaminyltransferase Gtfa from the Chloroeremomycin Biosynthetic Pathway.
Proc.Natl.Acad.Sci.USA, 100, 2003
1PRH
  • Download 1prh
  • View 1prh
Molmil generated image of 1prh
THE X-RAY CRYSTAL STRUCTURE OF THE MEMBRANE PROTEIN PROSTAGLANDIN H2 SYNTHASE-1
Descriptor:PROSTAGLANDIN H2 SYNTHASE-1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Picot, D., Loll, P.J., Garavito, R.M.
Deposit date:1994-03-07
Release date:1995-03-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1.
Nature, 367, 1994
1QRR
  • Download 1qrr
  • View 1qrr
Molmil generated image of 1qrr
CRYSTAL STRUCTURE OF SQD1 PROTEIN COMPLEX WITH NAD AND UDP-GLUCOSE
Descriptor:sulfolipid biosynthesis (SQD1) PROTEIN, SULFATE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Mulichak, A.M., Theisen, M.J., Essigmann, B., Benning, C., Garavito, R.M.
Deposit date:1999-06-15
Release date:1999-11-10
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of SQD1, an enzyme involved in the biosynthesis of the plant sulfolipid headgroup donor UDP-sulfoquinovose.
Proc.Natl.Acad.Sci.USA, 96, 1999
1RPN
  • Download 1rpn
  • View 1rpn
Molmil generated image of 1rpn
CRYSTAL STRUCTURE OF GDP-D-MANNOSE 4,6-DEHYDRATASE IN COMPLEXES WITH GDP AND NADPH
Descriptor:GDP-mannose 4,6-dehydratase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, GUANOSINE-5'-DIPHOSPHATE
Authors:Webb, N.A., Mulichak, A.M., Lam, J.S., Rocchetta, H.L., Garavito, R.M.
Deposit date:2003-12-03
Release date:2004-02-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structure of a tetrameric GDP-D-mannose 4,6-dehydratase from a bacterial GDP-D-rhamnose biosynthetic pathway.
Protein Sci., 13, 2004
1RRV
  • Download 1rrv
  • View 1rrv
Molmil generated image of 1rrv
X-RAY CRYSTAL STRUCTURE OF TDP-VANCOSAMINYLTRANSFERASE GTFD AS A COMPLEX WITH TDP AND THE NATURAL SUBSTRATE, DESVANCOSAMINYL VANCOMYCIN.
Descriptor:GLYCOSYLTRANSFERASE GTFD, DESVANCOSAMINYL VANCOMYCIN, POTASSIUM ION, ...
Authors:Mulichak, A.M., Lu, W., Losey, H.C., Walsh, C.T., Garavito, R.M.
Deposit date:2003-12-09
Release date:2004-05-18
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Vancosaminyltransferase Gtfd from the Vancomycin Biosynthetic Pathway: Interactions with Acceptor and Nucleotide Ligands
Biochemistry, 43, 2004
<123>